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1. Full Text Advance in Dietary Polyphenols as α-Glucosidases Inhibitors: A Review on Structure-Activity Relationship Aspect
by Xiao, Jianbo and Kai, Guoyin and Yamamoto, Koichiro and Chen, Xiaoqing
Critical Reviews in Food Science and Nutrition, ISSN 1040-8398, 01/2013, Volume 53, Issue 8, pp. 818 - 836
The dietary polyphenols as α-glucosidases inhibitors have attracted great interest among researchers. The aim of this review is to give an overview of the... 
Polyphenols | α-glucosidase | flavonoids | structure-activity relationship | Glycoside Hydrolase Inhibitors | Coumaric Acids - administration & dosage | Chalcone - chemistry | Stilbenes - administration & dosage | Coumaric Acids - chemistry | Humans | Catechin - administration & dosage | Tannins - chemistry | Stilbenes - chemistry | Structure-Activity Relationship | Hydrogenation | Anthocyanins - administration & dosage | Proanthocyanidins - chemistry | Proanthocyanidins - administration & dosage | Chalcone - administration & dosage | Hydroxylation | Glycosylation | Tannins - administration & dosage | Anthocyanins - chemistry | Diet | Polyphenols - chemistry | Methylation | Polyphenols - administration & dosage | Catechin - chemistry | alpha-Glucosidases - metabolism
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2. Full Text Dietary agents for prevention and treatment of lung cancer
by Khan, Naghma and Mukhtar, Hasan
Cancer Letters, ISSN 0304-3835, 2015, Volume 359, Issue 2, pp. 155 - 164
Highlights • Lung cancer has the highest cancer-related deaths in the United States. • Dietary modification could be an attractive approach for the prevention... 
Hematology, Oncology and Palliative Medicine | Prevention | Dietary agents | Treatment | Lung cancer | PHENETHYL ISOTHIOCYANATE | CARCINOMA CELLS | FACTOR-KAPPA-B | CELL-GROWTH | BENZYL ISOTHIOCYANATE | ONCOLOGY | SIGNALING PATHWAY | NUTRIENT MIXTURE | A/J MICE | TUMOR-GROWTH | GREEN TEA POLYPHENOL | Lung Neoplasms - drug therapy | Administration, Oral | Humans | Isothiocyanates - administration & dosage | Catechin - administration & dosage | Curcumin - administration & dosage | Adenocarcinoma - drug therapy | Indoles - administration & dosage | Plant Extracts - administration & dosage | Antineoplastic Agents, Phytogenic - administration & dosage | Adenocarcinoma - prevention & control | Animals | Lung Neoplasms - prevention & control | Anticarcinogenic Agents - administration & dosage | Flavonoids - administration & dosage | Catechin - analogs & derivatives | Polyphenols - administration & dosage | Respiratory agents | Care and treatment | Cancer | Tea | Kinases | Rodents | Tumors | lung cancer | treatment | prevention
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3. Full Text Evaluation of the Anti-inflammatory, Analgesic and Antipyretic Activities of the Natural Polyphenol Chlorogenic Acid
by dos Santos, Michel David and Almeida, Maria Camila and Lopes, Norberto Peporine and de Souza, Glória Emília Petto
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2006, Volume 29, Issue 11, pp. 2236 - 2240
Phenolic compounds are numerous and ubiquitous in the plant kingdom, being particularly present in health-promoting foods. Epidemiological evidences suggest... 
anti-inflammatory | lipopolysaccharide (LPS) | analgesic | formalin | carrageenin | chlorogenic acid | Formalin | Chlorogenic acid | Analgesic | Carrageenin | Anti-inflammatory | Lipopolysaccharide (LPS) | OXIDATIVE STRESS | DIETARY POLYPHENOLS | PHENOLIC-ACIDS | CAFFEIC ACID | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | RED WINE | FORMALIN TEST | NF-KAPPA-B | PROSTAGLANDIN E | CARRAGEENAN-INDUCED INFLAMMATION | Inflammation - chemically induced | Rats, Wistar | Lipopolysaccharides - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Pain - chemically induced | Fever - chemically induced | Flavonoids - therapeutic use | Dose-Response Relationship, Drug | Hindlimb - physiopathology | Time Factors | Formaldehyde - administration & dosage | Flavonoids - administration & dosage | Polyphenols | Molecular Structure | Formaldehyde - toxicity | Carrageenan - toxicity | Chlorogenic Acid - administration & dosage | Disease Models, Animal | Edema - prevention & control | Analgesics - therapeutic use | Drug Evaluation, Preclinical - methods | Lipopolysaccharides - toxicity | Pain - prevention & control | Administration, Oral | Analgesics - administration & dosage | Rats | Analgesics, Non-Narcotic - administration & dosage | Analgesics, Non-Narcotic - therapeutic use | Animals | Analgesics - chemistry | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Phenols - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Hindlimb - pathology | Chlorogenic Acid - therapeutic use | Fever - prevention & control | Hindlimb - drug effects | Phenols - administration & dosage | Phenols - chemistry | Inflammation - prevention & control | Edema - chemically induced | Chlorogenic Acid - chemistry | Flavonoids - chemistry | Analgesics, Non-Narcotic - chemistry | Carrageenan - administration & dosage
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4. Full Text Skin penetration behavior of lipid-core nanocapsules for simultaneous delivery of resveratrol and curcumin
by Friedrich, Rossana B and Kann, Birthe and Coradini, Karine and Offerhaus, Herman L and Beck, Ruy C.R and Windbergs, Maike
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 10/2015, Volume 78, pp. 204 - 213
Polyphenols, which are secondary plant metabolites, gain increasing research interest due to their therapeutic potential. Among them, resveratrol and curcumin... 
Skin penetration | Co-encapsulation | Cellular uptake | Curcumin | Resveratrol | Lipid-core nanocapsules | METIS-311680 | IR-97567 | ENCAPSULATION | PHOTOSTABILITY | TOXICITY | COMBINATION | FORMULATION | NANOPARTICLES | IN-VITRO | SPECTROSCOPY | ANTIOXIDANT | PHARMACOLOGY & PHARMACY | PERMEATION | Stilbenes - administration & dosage | Nanocapsules - administration & dosage | Curcumin - chemistry | Humans | Drug Carriers - administration & dosage | Oils - administration & dosage | Stilbenes - chemistry | Curcumin - administration & dosage | Nanocapsules - chemistry | Drug Carriers - chemistry | Hexoses - administration & dosage | Polyesters - administration & dosage | Grape Seed Extract - administration & dosage | Oils - chemistry | Cell Survival - drug effects | Cells, Cultured | Skin Absorption | Grape Seed Extract - chemistry | Polyesters - chemistry | Fibroblasts - drug effects | Polyphenols - chemistry | Drug Liberation | In Vitro Techniques | Polyphenols - administration & dosage | Hexoses - chemistry | Skin
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5. Full Text Formulation of a medical food cocktail for Alzheimer's disease: Beneficial effects on cognition and neuropathology in a mouse model of the disease
by Parachikova, Anna and Green, Kim N and Hendrix, Curt and Laferla, Frank M
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, p. e14015
Background: Dietary supplements have been extensively studied for their beneficial effects on cognition and AD neuropathology. The current study examines the... 
CURCUMIN | MEMORY DEFICITS | AMYLOID-BETA | PIPERINE | BIOLOGY | RATS | TEA POLYPHENOL (-)-EPIGALLOCATECHIN-3-GALLATE | RECOGNITION MEMORY | MICE | TRANSGENIC MODEL | TAU-PATHOLOGY | Memory - drug effects | Thioctic Acid - administration & dosage | Humans | Cerebral Cortex - pathology | Catechin - administration & dosage | Immunoblotting | Hippocampus - drug effects | Benzodioxoles - administration & dosage | Curcumin - administration & dosage | Folic Acid - administration & dosage | Vitamin B Complex - administration & dosage | Cerebral Cortex - physiopathology | Amyloid beta-Protein Precursor - metabolism | Cognition - physiology | Cerebral Cortex - drug effects | Acetylcysteine - administration & dosage | Alzheimer Disease - physiopathology | Piperidines - administration & dosage | Brain - physiopathology | Mice, Inbred C57BL | Alzheimer Disease - drug therapy | Ascorbic Acid - administration & dosage | Mice, Transgenic | Hippocampus - pathology | Cognition - drug effects | Maze Learning - drug effects | Mice, Inbred Strains | Brain - drug effects | Polyunsaturated Alkamides - administration & dosage | Amyloid beta-Protein Precursor - genetics | Animals | Brain - pathology | Alkaloids - administration & dosage | Catechin - analogs & derivatives | Mice | Alzheimer Disease - genetics | Dietary Supplements | Hippocampus - physiopathology | Vitamins - administration & dosage | Oligomers | Advertising executives | Catechin | Analysis | Dietary supplements | Acetylcysteine | Models | Genetic engineering | Research | Alzheimer's disease | Folic acid | Lipoic acid | Neurosciences | Memory | Cognitive ability | Neurobiology | Medical services | Cytotoxicity | Cognition | Antioxidants | Proteins | Learning | Ischemia | Transgenic animals | Rodents | Curcumin | Behavior | Neurological disorders | Food | Neurodegenerative diseases | Cortex | Ingredients | Transgenic mice | Studies | Pathology | Epigallocatechin gallate | Diet | β-Amyloid | Alzheimers disease | Hippocampus | Dementia
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6. Full Text Oral administration of the flavanol (−)‐epicatechin bolsters endogenous protection against focal ischemia through the Nrf2 cytoprotective pathway
by Leonardo, Christopher C and Agrawal, Megha and Singh, Nilendra and Moore, J. Russell and Biswal, Shyam and Doré, Sylvain
European Journal of Neuroscience, ISSN 0953-816X, 12/2013, Volume 38, Issue 11, pp. 3659 - 3668
Consumption of flavan‐3‐ols, notably (−)‐epicatechin (EC), has been highly recommended in complementary and alternative medicine (CAM) due to reports that... 
mouse | behavior | neuroinflammation | stroke | cultured neurons | Neuroinflammation | Cultured neurons | Stroke | Behavior | Mouse | RATS | NEUROSCIENCES | DAMAGE | BIOAVAILABILITY | POLYPHENOLS | ANTIOXIDANT DEFENSE | IN-VIVO | COCOA | CEREBRAL-ISCHEMIA | TRANSCRIPTION FACTOR | Neuroprotective Agents - therapeutic use | Infarction, Middle Cerebral Artery - physiopathology | Infarction, Middle Cerebral Artery - prevention & control | Oxidative Stress | Catechin - administration & dosage | Male | Infarction, Middle Cerebral Artery - metabolism | Neuroglia - drug effects | Neuroprotective Agents - pharmacology | Neurons - physiology | Catechin - therapeutic use | Neurons - metabolism | Catechin - pharmacology | Neurons - drug effects | Neuroprotective Agents - administration & dosage | Movement | Administration, Oral | Cell Survival | Mice, Inbred C57BL | Cells, Cultured | Neuroglia - physiology | Animals | NF-E2-Related Factor 2 - metabolism | Neuroglia - metabolism | Mice | Antioxidants | Glucose metabolism | Ischemia | Analysis | Alternative medicine | Glucose | Dextrose | Animal models
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7. Full Text Distribution of [3H] trans-resveratrol in rat tissues following oral administration
by El-Mohsen, Manal Abd and Bayele, Henry and Kuhnle, Gunter and Gibson, Glenn and Debnam, Edward and Srai, S. Kaila and Rice-Evans, Catherine and Spencer, Jeremy P. E
British Journal of Nutrition, ISSN 0007-1145, 1/2006, Volume 96, Issue 1, pp. 62 - 70
Resveratrol has been widely investigated for its potential health properties, although little is known about its metabolism in vivo. Here we investigated the... 
Polyphenol | Metabolism | Radioactive | Distribution | Resveratrol | WINE | ACID | radioactive | HUMANS | polyphenol | distribution | BIOAVAILABILITY | POLYPHENOLS | NUTRITION & DIETETICS | TRANS-RESVERATROL | metabolism | ABSORPTION | resveratrol | DERIVATIVES | Chromatography, High Pressure Liquid - methods | Stilbenes - administration & dosage | Enzyme Inhibitors - metabolism | Administration, Oral | Glucuronides - analysis | Lung - chemistry | Rats | Male | Stilbenes - metabolism | Tritium | Rats, Sprague-Dawley | Liver - chemistry | Spleen - chemistry | Enzyme Inhibitors - administration & dosage | Tissue Distribution | Absorption | Animals | Enzyme Inhibitors - pharmacokinetics | Myocardium - metabolism | Stilbenes - pharmacokinetics | Kidney - chemistry | Brain Chemistry
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8. Full Text Distribution of [ 14C]- trans-resveratrol, a cancer chemopreventive polyphenol, in mouse tissues after oral administration
by Vitrac, Xavier and Desmoulière, Alexis and Brouillaud, Brigitte and Krisa, Stéphanie and Deffieux, Gérard and Barthe, Nicole and Rosenbaum, Jean and Mérillon, Jean-Michel
Life Sciences, ISSN 0024-3205, 2003, Volume 72, Issue 20, pp. 2219 - 2233
Trans-resveratrol, a phenolic compound present in wine, has been reported to be a potential cancer chemopreventive agent. However, although it has numerous... 
Red wine | Whole-body autoradiography | Bioavailability | MEDICINE, RESEARCH & EXPERIMENTAL | whole-body autoradiography | red wine | CIS-RESVERATROL 3,4',5-TRIHYDROXYSTILBENE | RATS | SMALL-INTESTINE | CORONARY HEART-DISEASE | VINIFERA CELL-CULTURES | GRAPEVINE-DERIVED POLYPHENOL | EPITHELIAL-CELLS | bioavailability | GROWTH | TRANS-RESVERATROL | PHARMACOLOGY & PHARMACY | RED-WINE | Stilbenes - administration & dosage | Administration, Oral | Biological Availability | Male | Chromatography, High Pressure Liquid | Anticarcinogenic Agents - pharmacokinetics | Tissue Distribution | Autoradiography | Animals | Anticarcinogenic Agents - administration & dosage | Resveratrol | Stilbenes - pharmacokinetics | Mice | Mice, Inbred BALB C | Carbon Radioisotopes
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9. Full Text Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis
by Panahi, Yunes and Hosseini, Mahboobeh Sadat and Khalili, Nahid and Naimi, Effat and Majeed, Muhammed and Sahebkar, Amirhossein
Clinical Nutrition, ISSN 0261-5614, 2015, Volume 34, Issue 6, pp. 1101 - 1108
Summary Background Oxidative stress and inflammation have been proposed as emerging components of metabolic syndrome (MetS). Curcuminoids are natural... 
Gastroenterology and Hepatology | Turmeric | Cardiovascular disease | Antioxidant | Curcuma longa | Randomized controlled trial | C-REACTIVE PROTEIN | OXIDATIVE STRESS | MYOCARDIAL-INFARCTION | RISK | ENDOTHELIAL FUNCTION | IN-VITRO | NUTRITION & DIETETICS | INFLAMMATION | DOUBLE-BLIND | CLINICAL-PRACTICE | ASSOCIATION | Blood Pressure | Meta-Analysis as Topic | Alkaloids - pharmacokinetics | Humans | Middle Aged | Superoxide Dismutase - blood | Biological Availability | Male | Benzodioxoles - administration & dosage | Curcumin - administration & dosage | Metabolic Syndrome - drug therapy | C-Reactive Protein - metabolism | Benzodioxoles - pharmacokinetics | Inflammation - drug therapy | Malondialdehyde - blood | Adult | Anti-Inflammatory Agents - administration & dosage | Anti-Inflammatory Agents - pharmacokinetics | Female | Piperidines - pharmacokinetics | Databases, Factual | Body Mass Index | Piperidines - administration & dosage | Double-Blind Method | Curcumin - pharmacokinetics | Polyunsaturated Alkamides - administration & dosage | Antioxidants - administration & dosage | Alkaloids - administration & dosage | Polyunsaturated Alkamides - pharmacokinetics | Oxidative Stress - drug effects | Antioxidants - pharmacokinetics | Dietary Supplements | Antioxidants | Polyphenols | Anti-inflammatory drugs | Analysis
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10. Full Text Continuous administration of polyphenols from aqueous rooibos ( Aspalathus linearis) extract ameliorates dietary-induced metabolic disturbances in hyperlipidemic mice
by Beltrán-Debón, R and Rull, A and Rodríguez-Sanabria, F and Iswaldi, I and Herranz-López, M and Aragonès, G and Camps, J and Alonso-Villaverde, C and Menéndez, J.A and Micol, V and Segura-Carretero, A and Joven, J
Phytomedicine, ISSN 0944-7113, 2011, Volume 18, Issue 5, pp. 414 - 424
The incidence of obesity and related metabolic diseases is increasing globally. Current medical treatments often fail to halt the progress of such... 
Macrophage recruitment | Obesity | Aspalathus linearis | Hyperlipidemia | Polyphenols | Hepatic steatosis | LDLr-deficient mice | CHEMISTRY, MEDICINAL | PHENOLIC-COMPOUNDS | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | PLANT SCIENCES | TEA | INTEGRATIVE & COMPLEMENTARY MEDICINE | PHARMACOLOGY & PHARMACY | RUTIN | Plant Extracts - chemistry | AMP-Activated Protein Kinases - metabolism | Liver - enzymology | Cholesterol, Dietary - administration & dosage | Plant Extracts - pharmacology | Cholesterol - blood | Polyphenols - pharmacology | Diet, High-Fat - adverse effects | Male | AMP-Activated Protein Kinases - drug effects | Plant Extracts - administration & dosage | Liver - drug effects | Weight Gain - drug effects | Disease Models, Animal | Aspalathus - chemistry | Liver - metabolism | Mice, Inbred C57BL | Fatty Liver - prevention & control | Mice, Transgenic | Energy Intake - drug effects | 3T3-L1 Cells | Enzyme Activation - drug effects | Eating - drug effects | Animals | Polyphenols - chemistry | Adipose Tissue, White - enzymology | Triglycerides - blood | Mice | Polyphenols - administration & dosage | Adipose Tissue, White - drug effects | Fatty Liver - etiology | Care and treatment | Research | Health aspects | Rooibos tea
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11. Health benefits of resveratrol administration
by Galiniak, Sabina and Aebisher, David and Bartusik-Aebisher, Dorota
Acta biochimica Polonica, ISSN 0001-527X, 02/2019, Volume 66, Issue 1, pp. 13 - 21
Resveratrol is a polyphenol that is abundant in grape skin and seeds. Food sources of resveratrol include wine, berries, and peanuts. This compound has many... 
LIFE-SPAN | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SELF-RENEWAL | DIABETIC-NEPHROPATHY | polyphenol | ANTIOXIDANT PROPERTIES | glycation | NEUROPATHIC PAIN | TRANS-RESVERATROL | MITOCHONDRIAL DYSFUNCTION | resveratrol | oxidative stress | GLYCATION END-PRODUCTS
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12. Full Text Apple Procyanidin Oligomers Absorption in Rats after Oral Administration:  Analysis of Procyanidins in Plasma Using the Porter Method and High-Performance Liquid Chromatography/Tandem Mass Spectrometry
by Shoji, Toshihiko and Masumoto, Saeko and Moriichi, Nina and Akiyama, Hiroshi and Kanda, Tomomasa and Ohtake, Yasuyuki and Goda, Yukihiro
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 02/2006, Volume 54, Issue 3, pp. 884 - 892
In this study, we investigated the absorption of apple procyanidins, namely, apple condensed tannins (ACTs), in rats using the Porter method and... 
Procyanidin trimers | Absorption | HPLC/MS/MS | Procyanidin dimers | Apple procyanidins | CELLS | C-14-LABELED CONDENSED TANNINS | PROANTHOCYANIDINS | absorption | procyanidin trimers | FOOD SCIENCE & TECHNOLOGY | GASTROINTESTINAL-TRACT | MOUSE | EXCRETION | POLYPHENOLS | METABOLISM | AGRICULTURE, MULTIDISCIPLINARY | procyanidin dimers | apple procyanidins | MALUS-PUMILA | CHEMISTRY, APPLIED | GRAPE SEED EXTRACT | Proanthocyanidins - administration & dosage | Animals | Flavonols - analysis | Fruit - chemistry | Malus - chemistry | Mass Spectrometry | Rats | Proanthocyanidins - pharmacokinetics | Chromatography, High Pressure Liquid | Proanthocyanidins - blood | Dimerization
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13. Full Text Habitual intake of flavonoid subclasses and incident hypertension in adults
by Cassidy, Aedín and O'Reilly, Éilis J and Kay, Colin and Sampson, Laura and Franz, Mary and Forman, J.P and Curhan, Gary and Rimm, Eric B
American Journal of Clinical Nutrition, ISSN 0002-9165, 02/2011, Volume 93, Issue 2, pp. 338 - 347
Background: Dietary flavonoids have beneficial effects on blood pressure in intervention settings, but there is limited information on habitual intake and risk... 
UNITED-STATES | NADPH OXIDASE | NUTRITION & DIETETICS | NITRIC-OXIDE SYNTHASE | FOOD FREQUENCY QUESTIONNAIRE | FLAVANOL-RICH COCOA |