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Journal of Controlled Release, ISSN 0168-3659, 01/2015, Volume 197, pp. 48 - 57
Journal Article
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 07/2014, Volume 103, Issue 7, pp. 2072 - 2087
The present study aims at elucidating the intricate nature of the drug release and absorption following intramuscular (i.m.) injection of sustained-release... 
apparent terminal half-life in plasma | sustained release | weight-normalized apparent drug clearance | polarized light microscopy | histopathology | intramuscular | PBPK | observed maximum drug plasma concentration | physiologically based pharmacokinetic | ORO | AUC | PLM | PPP | nanoparticles | haematoxylin and eosin | inflammation | muscle | TMAX | pharmacokinetics | paliperidone | active pharmaceutical ingredient | laser diffraction | Oil Red O | transmission electron microscopy | time of occurrence of observed maximum drug plasma concentration | scanning electron microscopy | Dv,50 | biocompatibility | polystyrene | T1/2 | i.m | s.c | prodrugs | paliperidone palmitate | area under the (plasma concentration vs. time) curve | subcutaneously | disposition | long-acting injectable | LAI | median equivalent sphere diameter | API | SEM | TEM | CMAX | CL/F | DRUG | PHAGOCYTOSIS | CHEMISTRY, MEDICINAL | MICROSPHERES | PHARMACEUTICALS | MACROPHAGES | CHEMISTRY, MULTIDISCIPLINARY | IN-VITRO | TISSUE-RESPONSE | PHARMACOLOGY & PHARMACY | PARTICLE-SIZE | ABSORPTION | EXPRESSION | Immunohistochemistry | Prodrugs - administration & dosage | Inflammation - pathology | Rats, Wistar | Male | Muscle, Skeletal - metabolism | Prodrugs - chemistry | Nanoparticles | Tissue Distribution | Inflammation - metabolism | Palmitates - administration & dosage | Surface Properties | Suspensions | Isoxazoles - pharmacokinetics | Microscopy, Electron, Transmission | Paliperidone Palmitate | Palmitates - chemistry | Injections, Intramuscular | Isoxazoles - chemistry | Isoxazoles - administration & dosage | Particle Size | Animals | Prodrugs - pharmacokinetics | Models, Biological | Palmitates - pharmacokinetics | Muscle, Skeletal - pathology | Delayed-Action Preparations | Pharmacists | Antipsychotic drugs | Index Medicus
Journal Article
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 05/2008, Volume 325, Issue 2, pp. 400 - 408
Journal Article
International Journal of Nanomedicine, ISSN 1176-9114, 03/2013, Volume 8, Issue 1, pp. 877 - 887
Purpose: The aim of this report was to introduce a novel "core-membrane" microgel drug-delivery device for spontaneously pulsed release without any external... 
Polyelectrolyte | Pulsed drug delivery | Chitosan-alginate | Layer-by-layer | Microgels | chitosan-alginate | IN-VITRO RELEASE | HYDROGELS | DESIGN | layer-by-layer | polyelectrolyte | DEXTRAN | DEVICE | NANOSCIENCE & NANOTECHNOLOGY | PULSATILE DELIVERY | BEADS | microgels | PHARMACOLOGY & PHARMACY | MICROCAPSULES | PROTEINS | pulsed drug delivery | Polyamines - administration & dosage | Fluorescein-5-isothiocyanate - pharmacokinetics | Hexuronic Acids - administration & dosage | Dextrans - chemistry | Male | Polystyrenes - chemistry | Dextrans - pharmacokinetics | Technology, Pharmaceutical | Fluorescein-5-isothiocyanate - chemistry | Polystyrenes - administration & dosage | Gels - chemistry | Glucuronic Acid - administration & dosage | Glucuronic Acid - chemistry | Polyamines - chemistry | Fluorescein-5-isothiocyanate - administration & dosage | Gels - administration & dosage | Chitosan - administration & dosage | Fluorescein-5-isothiocyanate - analogs & derivatives | Hexuronic Acids - chemistry | Pressure | Alginates - administration & dosage | Animals | Chitosan - chemistry | Alginates - chemistry | Mice | Delayed-Action Preparations | Dextrans - administration & dosage | Drug Delivery Systems - methods | Microtechnology | Drugs | Drug delivery systems | Polyelectrolytes | Chitin | Research | Coatings | Health aspects | Vehicles | Index Medicus | Original Research
Journal Article
Nanomedicine: Nanotechnology, Biology, and Medicine, ISSN 1549-9634, 2015, Volume 11, Issue 5, pp. 1227 - 1236
Abstract We are investigating an imaging agent that detects early-stage primary colorectal cancer on the mucosal surface in real time under colonoscopic... 
Internal Medicine | Toxicity study | Good Laboratory Practice | Colonoscopic imaging agent | Nanosphere | Colorectal cancer | IMMOBILIZED FLUORESCENT NANOSPHERES | THOMSEN-FRIEDENREICH ANTIGEN | DRUG | MEDICINE, RESEARCH & EXPERIMENTAL | NANOSCIENCE & NANOTECHNOLOGY | AMPHOTERICIN-B | DELIVERY | CURRENT STATE | NANOPARTICLES | HYDROPHILIC POLYMERIC CHAINS | EARLY COLORECTAL-CANCER | NANOTECHNOLOGY | Cricetulus | Peanut Agglutinin - administration & dosage | Rectum - pathology | Humans | Nanospheres - chemistry | Colon - drug effects | Body Weight - drug effects | Coumarins - chemistry | Male | Thiazoles - administration & dosage | Polystyrenes - toxicity | Colorectal Neoplasms - diagnosis | Polystyrenes - chemistry | Rectum - drug effects | Polystyrenes - administration & dosage | Colonoscopy | Acetamides - toxicity | Fluorescent Dyes - administration & dosage | Coumarins - toxicity | CHO Cells | Caco-2 Cells | Fluorescent Dyes - chemistry | Peanut Agglutinin - chemistry | Colon - pathology | Coumarins - administration & dosage | Rats | Nanospheres - toxicity | Peanut Agglutinin - toxicity | Eating - drug effects | Thiazoles - toxicity | Acetamides - chemistry | Animals | Polyvinyls - administration & dosage | Fluorescent Dyes - toxicity | Thiazoles - chemistry | Drinking - drug effects | Polyvinyls - toxicity | Polyvinyls - chemistry | Acetamides - administration & dosage | Nanospheres - administration & dosage | Imaging systems | Index Medicus
Journal Article
Journal Article
Journal Article
ACS Nano, ISSN 1936-0851, 07/2013, Volume 7, Issue 7, pp. 5858 - 5869
Journal Article