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1. Full Text Drug Delivery with PEGylated MoS2 Nano‐sheets for Combined Photothermal and Chemotherapy of Cancer
by Liu, Teng and Wang, Chao and Gu, Xing and Gong, Hua and Cheng, Liang and Shi, Xiaoze and Feng, Liangzhu and Sun, Baoquan and Liu, Zhuang
Advanced Materials, ISSN 0935-9648, 06/2014, Volume 26, Issue 21, pp. 3433 - 3440
MoS2 nanosheets functionalized with poly­ethylene glycol are for the first time used as a multifunctional drug delivery system with high drug loading... 
MoS2 nanosheet | combination therapy | drug delivery | 2D nanostructure | photothermal therapy | GRAPHENE OXIDE | CELLS | PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | METAL DICHALCOGENIDE NANOSHEETS | NANOSCIENCE & NANOTECHNOLOGY | TUMOR VASCULATURE | CHEMISTRY, MULTIDISCIPLINARY | NANOPARTICLES | THERAPY | NANOGRAPHENE | CHEMISTRY | NANOTUBES | Molybdenum - chemistry | Drug Carriers - adverse effects | Porphyrins - administration & dosage | Humans | Polyethylene Glycols - adverse effects | Polyethylene Glycols - chemistry | Antineoplastic Agents - administration & dosage | Porphyrins - pharmacokinetics | Radiation-Sensitizing Agents - pharmacokinetics | Drug Carriers - chemistry | Phototherapy - methods | Molybdenum - adverse effects | Radiation-Sensitizing Agents - administration & dosage | Disulfides - chemistry | Camptothecin - administration & dosage | Female | Nanostructures - adverse effects | Antineoplastic Agents - pharmacokinetics | Camptothecin - analogs & derivatives | Doxorubicin - administration & dosage | Camptothecin - pharmacokinetics | Cell Survival - drug effects | KB Cells | Disulfides - adverse effects | Combined Modality Therapy | Disulfides - chemical synthesis | Doxorubicin - pharmacokinetics | Mammary Neoplasms, Experimental - therapy | Pilot Projects | Animals | Cell Line, Tumor | Nanostructures - chemistry | Mice | Mice, Inbred BALB C | Polyethylene Glycols - chemical synthesis | HeLa Cells | Drugs | Chemotherapy | Drug delivery systems | Vehicles | Cancer
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2. Full Text Combined chemotherapy and photodynamic therapy using a nanohybrid based on layered double hydroxides to conquer cisplatin resistance
by Wang, Zhigang and Ma, Rong and Yan, Li and Chen, Xianfeng and Zhu, Guangyu
Chemical communications (Cambridge, England), ISSN 1359-7345, 07/2015, Volume 51, Issue 58, pp. 11587 - 11590
A nanohybrid is assembled by ratiometrically co-loading Pt(IV) prodrugs and photosensitizers into layered double hydroxide nanoparticles. The nanohybrid shows... 
Prodrugs - administration & dosage | Cell Survival - drug effects | Porphyrins - administration & dosage | Humans | Drug Resistance, Neoplasm | Antineoplastic Agents - administration & dosage | Hydroxides - pharmacology | Porphyrins - pharmacology | Photochemotherapy | Photosensitizing Agents - administration & dosage | Photosensitizing Agents - pharmacology | Cell Line, Tumor | Hydroxides - administration & dosage | Antineoplastic Agents - pharmacology | Nanoparticles - administration & dosage | Platinum Compounds - administration & dosage | Platinum Compounds - pharmacology | Prodrugs - pharmacology
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3. Full Text Drug-induced co-assembly of albumin/catalase as smart nano-theranostics for deep intra-tumoral penetration, hypoxia relieve, and synergistic combination therapy
by Chen, Jiawen and Chen, Qian and Liang, Chao and Feng, Liangzhu and Dong, Ziliang and Song, Guosheng and Song, Xuejiao and Liu, Zhuang
Journal of Controlled Release, ISSN 0168-3659, 10/2017, Volume 263, pp. 79 - 89
The abnormal tumor microenvironment (TME) featured with hypoxia, acidosis, dense extracellular matrix and increased tumor interstitial fluid pressure is... 
Albumin | Deep penetration | Hypoxia relieve | Self-assembly | Combination therapy | PHOTODYNAMIC THERAPY | CHEMISTRY, MULTIDISCIPLINARY | CANCER-THERAPY | OXYGEN | NANOPARTICLES | GUIDED PHOTOTHERMAL THERAPY | MICROENVIRONMENT | PHARMACOLOGY & PHARMACY | HYDROGEN-PEROXIDE | ENZYME ENCAPSULATION | RADIOTHERAPY | Neoplasms - metabolism | Porphyrins - administration & dosage | Catalase - therapeutic use | Theranostic Nanomedicine | Nanoparticles - chemistry | Porphyrins - chemistry | Serum Albumin - administration & dosage | Tumor Microenvironment | Hydrogen Peroxide - chemistry | Radiation-Sensitizing Agents - therapeutic use | Paclitaxel - chemistry | Antineoplastic Agents, Phytogenic - administration & dosage | Neoplasms - therapy | Radiation-Sensitizing Agents - administration & dosage | Nanoparticles - therapeutic use | Female | Radiation-Sensitizing Agents - chemistry | Antineoplastic Agents, Phytogenic - therapeutic use | Paclitaxel - administration & dosage | Serum Albumin - chemistry | Porphyrins - therapeutic use | Antineoplastic Agents, Phytogenic - chemistry | Combined Modality Therapy | Paclitaxel - therapeutic use | Serum Albumin - therapeutic use | Catalase - administration & dosage | Animals | Mice, Nude | Cell Line, Tumor | Hypoxia | Nanoparticles - administration & dosage | Neoplasms - pathology | Catalase - chemistry | Chemotherapy | Pharmaceutical industry | Cancer | Enzymes
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4. Full Text Porphyrin dye into biopolymeric chitosan films for localized photodynamic therapy of cancer
by Ferreira, D.P and Ferreira, I.C.F.R and Conceição, D.S and Calhelha, R.C and Sousa, T and Socoteanu, Radu and Vieira Ferreira, L.F
Carbohydrate Polymers, ISSN 0144-8617, 10/2016, Volume 151, pp. 160 - 171
Porphyrins and some of its derivatives are well known and widely used as photosensitizers (PSs) for Photodynamic Therapy of Cancer (PDT). The present study... 
HeLa cells | PEG | Chitosan | Porphyrin | Gelatin | Photochemistry | MOLECULAR-INTERACTIONS | POLYMER SCIENCE | PHOTOSENSITIZERS | CONTROLLED-RELEASE | CHEMISTRY, ORGANIC | DELIVERY | HeLa Cells | CHEMISTRY, APPLIED | LIPOPHILIC PORPHYRIN | POLYETHYLENE-GLYCOL | DERIVATIVES | MORPHOLOGY | Cell Survival - drug effects | Porphyrins - administration & dosage | Coloring Agents - administration & dosage | Gelatin - administration & dosage | Photosensitizing Agents - chemistry | Humans | Porphyrins - chemistry | Chitosan - administration & dosage | Drug Carriers - administration & dosage | Fluorescence | Polyethylene Glycols - chemistry | Photochemotherapy | Drug Carriers - chemistry | Polyethylene Glycols - administration & dosage | Neoplasms - drug therapy | Photosensitizing Agents - administration & dosage | Chitosan - chemistry | Light | Drug Liberation | Gelatin - chemistry | Coloring Agents - chemistry | Care and treatment | Health aspects | Nanotechnology | Porphyrins | Cancer | Index Medicus
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5. Full Text Comparison between intravesical and oral administration of 5‐aminolevulinic acid in the clinical benefit of photodynamic diagnosis for nonmuscle invasive bladder cancer
by Inoue, Keiji and Fukuhara, Hideo and Shimamoto, Tsutomu and Kamada, Masayuki and Iiyama, Tatsuo and Miyamura, Mitsuhiko and Kurabayashi, Atsushi and Furihata, Mutsuo and Tanimura, Masanobu and Watanabe, Hironobu and Shuin, Taro
Cancer, ISSN 0008-543X, 02/2012, Volume 118, Issue 4, pp. 1062 - 1074
BACKGROUND: This study was undertaken to evaluate the clinical value of photodynamic diagnosis (PDD) with intravesical and oral instillation of... 
5‐aminolevulinic acid | nonmuscle invasive bladder cancer | photodynamic diagnosis | intravesical recurrence | administration route | 5-aminolevulinic acid | INDUCED PROTOPORPHYRIN-IX | AMINOLEVULINIC ACID | ENDOSCOPIC DETECTION | INSTILLATION | RELEVANT REDUCTION | TUMORS | INDUCED FLUORESCENCE DIAGNOSIS | ONCOLOGY | TRANSITIONAL-CELL CARCINOMA | RECURRENCE | TRANSURETHRAL RESECTION | Neoplasm Invasiveness - diagnosis | Prognosis | Administration, Oral | Urinary Bladder Neoplasms - diagnosis | Humans | Middle Aged | Fluorescence | Male | Urinary Bladder Neoplasms - surgery | Aminolevulinic Acid - administration & dosage | Photosensitizing Agents - administration & dosage | Neoplasm Invasiveness - pathology | Sensitivity and Specificity | Survival Analysis | Urinary Bladder Neoplasms - pathology | Aged, 80 and over | Adult | Female | Aged | Retrospective Studies | Administration, Intravesical | Cystectomy - methods | Usage | Carcinoma in situ | Diagnosis | Research | Drug therapy | Photochemotherapy | Bladder cancer | Health aspects | Porphyrins | Cancer
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6. Full Text Enhanced blood suspensibility and laser-Activated tumor-specific drug release of theranostic mesoporous silica nanoparticles by functionalizing with erythrocyte membranes
by Su, Jinghan and Sun, Huiping and Meng, Qingshuo and Zhang, Pengcheng and Yin, Qi and Li, Yaping
Theranostics, ISSN 1838-7640, 2017, Volume 7, Issue 3, pp. 523 - 537
Mesoporous silica nanoparticles (MSNs), with their large surface area and tunable pore sizes, have been widely applied for anticancer therapeutic cargos... 
Drug release | Mesoporous silica nanoparticles | RBC-mimetic | Fluorescence imaging | Metastasis | MEDICINE, RESEARCH & EXPERIMENTAL | CELL-MEMBRANE | SHELL | PHOTODYNAMIC THERAPY | GENE DELIVERY | GOLD NANORODS | PENETRATION | CHEMOTHERAPY | BREAST-CANCER | POLYMERIC NANOPARTICLES | RESISTANCE | Silicon Dioxide - administration & dosage | Porphyrins - administration & dosage | Erythrocyte Membrane - radiation effects | Drug Carriers - administration & dosage | Drug Liberation - radiation effects | Antineoplastic Agents - administration & dosage | Porphyrins - pharmacokinetics | Breast Neoplasms - drug therapy | Doxorubicin - pharmacokinetics | Photosensitizing Agents - administration & dosage | Animals | Lasers | Photosensitizing Agents - pharmacokinetics | Antineoplastic Agents - pharmacokinetics | Mice | Nanoparticles - administration & dosage | Breast Neoplasms - diagnostic imaging | Disease Models, Animal | Doxorubicin - administration & dosage
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7. Full Text Early and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damage
by Gauter-Fleckenstein, Benjamin and Fleckenstein, Katharina and Owzar, Kouros and Jiang, Chen and Rebouças, Júlio S and Batinic-Haberle, Ines and Vujaskovic, Zeljko
Free Radical Biology and Medicine, ISSN 0891-5849, 04/2010, Volume 48, Issue 8, pp. 1034 - 1043
Chronic production of reactive oxygen and nitrogen species is an underlying mechanism of irradiation (IR)-induced lung injury. The purpose of this study was to... 
Oxidative stress | Free radicals | Manganese porphyrin | Radioprotector | Radiation | MnTE-2-PyP | Lung injury | INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTECTS LUNGS | CHRONIC OXIDATIVE STRESS | MnTE-2-PyP5 | ANGIOTENSIN-CONVERTING ENZYME | CATALYTIC METALLOPORPHYRIN ANTIOXIDANT | REACTIVE OXYGEN | ENDOCRINOLOGY & METABOLISM | IONIZING-RADIATION | SUPEROXIDE-DISMUTASE | NORMAL TISSUE-INJURY | Animals | Radiation Pneumonitis - pathology | Time Factors | Metalloporphyrins - administration & dosage | Rats, Inbred F344 | Antioxidants - administration & dosage | Radiation-Protective Agents - pharmacology | Rats | Female | Respiration | Radiation Pneumonitis - drug therapy | radioprotector | lung injury | radiation | oxidative stress | manganese porphyrin
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8. Full Text Dermal administration of manganese porphyrin by iontophoresis
by Ito, Fuminori and Imamura, Shinya and Asayama, Shoichiro and Kanamura, Kiyoshi and Kawakami, Hiroyoshi
Materials Science & Engineering C, ISSN 0928-4931, 08/2014, Volume 41, pp. 349 - 353
The present study describes a technique for dermal administration of cationic manganese porphyrin (Mn-porphyrin), an antioxidant with superoxide dismutase... 
Iontophoresis | Hairless mouse | Superoxide dismutase | Dermal administration | Mn-porphyrin | Permeation test | MATERIALS SCIENCE, BIOMATERIALS | SUPEROXIDE-DISMUTASE | Antioxidants - chemistry | Antioxidants - metabolism | Porphyrins - chemistry | Mice, Hairless | Administration, Cutaneous | Manganese - chemistry | Animals | Time Factors | Mice | In Vitro Techniques | Spectrophotometry | Antioxidants - analysis | Skin - pathology | Antioxidants | Skin | Superoxide | Manganese | Porphyrins | Diffusion barriers | Barriers | Surface chemistry | Sod | Chemical compounds
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9. Full Text Hyaluronan-decorated polymer nanoparticles targeting the CD44 receptor for the combined photo/chemo-therapy of cancer
by Maiolino, Sara and Moret, Francesca and Conte, Claudia and Fraix, Aurore and Tirino, Pasquale and Ungaro, Francesca and Sortino, Salvatore and Reddi, Elena and Quaglia, Fabiana
Nanoscale, ISSN 2040-3364, 03/2015, Volume 7, Issue 13, pp. 5643 - 5653
In the attempt to develop novel concepts in designing targeted nanoparticles for combination therapy of cancer, we propose here CD44-targeted... 
Cell Survival - drug effects | Porphyrins - administration & dosage | Coated Materials, Biocompatible - chemical synthesis | Nanocapsules - administration & dosage | Photochemotherapy - methods | Humans | Hyaluronic Acid - chemistry | Coated Materials, Biocompatible - administration & dosage | Treatment Outcome | Hyaluronic Acid - pharmacokinetics | Breast Neoplasms - drug therapy | Nanocapsules - chemistry | Nanocapsules - ultrastructure | Antibiotics, Antineoplastic - administration & dosage | Photosensitizing Agents - administration & dosage | Antibiotics, Antineoplastic - chemistry | MCF-7 Cells | Breast Neoplasms - pathology | Hyaluronan Receptors - metabolism | Cell Line, Tumor | Polymers - chemistry | Combined Modality Therapy - methods | Diffusion | Doxorubicin - administration & dosage
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10. Full Text Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury
by Rabbani, Zahid N., M.D and Batinic-Haberle, Ines, Ph.D and Anscher, Mitchell S., M.D and Huang, Jie, M.D and Day, Brian J., Ph.D and Alexander, Elaine, M.D., Ph.D and Dewhirst, Mark W., D.V.M., Ph.D and Vujaskovic, Zeljko, M.D., Ph.D
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2007, Volume 67, Issue 2, pp. 573 - 580
Purpose: To determine whether administration of a catalytic antioxidant, Mn(III) tetrakis(N,N′-diethylimidazolium-2-yl) porphyrin, AEOL 10150, with superoxide... 
Radiology | Hematology, Oncology and Palliative Medicine | Superoxide dismutase mimetic | Rat | AEOL 10150 | Pulmonary toxicity | Radiation | INDUCED PULMONARY FIBROSIS | OXIDATIVE STRESS | rat | MANGANESE PORPHYRINS | BONE-MARROW | superoxide dismutase mimetic | pulmonary toxicity | INTRATRACHEAL INJECTION | DIFFERENTIAL RADIOPROTECTION | ONCOLOGY | radiation | HUMAN-DIPLOID FIBROBLASTS | GENE-THERAPY | MICE | EXTRACELLULAR-SUPEROXIDE DISMUTASE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Macrophages - physiology | Cell Count | Rats, Inbred F344 | Radiation-Protective Agents - administration & dosage | Rats | Deoxyguanosine - analysis | Random Allocation | Radiation Injuries, Experimental - prevention & control | Animals | Radiation Injuries - prevention & control | Metalloporphyrins - administration & dosage | Antioxidants - administration & dosage | Female | Lung - radiation effects | Deoxyguanosine - analogs & derivatives | Antioxidants | Porphyrins | OXIDATION | COLLAGEN | INJURIES | SUPEROXIDE DISMUTASE | ANTIOXIDANTS | MACROPHAGES | LUNGS | PORPHYRINS | RATS | RADIATION DOSES | TOXICITY | HISTOLOGY | BIOLOGICAL STRESS | DAMAGE | IRRADIATION | ANOXIA | RESPIRATION | DRUGS | CHRONIC INTAKE | RADIOLOGY AND NUCLEAR MEDICINE | BLOOD | AEOL10150
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11. Full Text Multimodal image-guided surgical and photodynamic interventions in head and neck cancer: From primary tumor to metastatic drainage
by Muhanna, Nidal and Cui, Liyang and Chan, Harley and Burgess, Laura and Jin, Cheng S and MacDonald, Thomas D and Huynh, Elizabeth and Wang, Fan and Chen, Juan and Irish, Jonathan C and Zheng, Gang
Clinical Cancer Research, ISSN 1078-0432, 02/2016, Volume 22, Issue 4, pp. 961 - 970
Purpose: The low survival rate of head and neck cancer (HNC) patients is attributable to late disease diagnosis and high recurrence rate. Current HNC staging... 
SENTINEL NODE BIOPSY | THERAPY | ONCOLOGY | LYMPH-NODES | SQUAMOUS-CELL CARCINOMA | SMOKING | EMISSION-TOMOGRAPHY | SHOULDER MORBIDITY | TOBACCO | Porphyrins - administration & dosage | Rabbits | Dimyristoylphosphatidylcholine - administration & dosage | Humans | Head and Neck Neoplasms - drug therapy | Carcinoma, Squamous Cell - surgery | Combined Modality Therapy | Lymphatic Metastasis | Antineoplastic Agents - administration & dosage | Photochemotherapy | Head and Neck Neoplasms - pathology | Photosensitizing Agents - administration & dosage | Xenograft Model Antitumor Assays | Animals | Carcinoma, Squamous Cell - drug therapy | Cholesterol Esters - administration & dosage | Surgery, Computer-Assisted | Cell Line, Tumor | Photosensitizing Agents - pharmacokinetics | Carcinoma, Squamous Cell - secondary | Antineoplastic Agents - pharmacokinetics | Nanoparticles - administration & dosage | Head and Neck Neoplasms - surgery | Apoptosis
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12. Full Text Photodynamic detection of canine mammary gland tumours after oral administration of 5‐aminolevulinic acid
by Osaki, T and Yokoe, I and Ogura, S and Takahashi, K and Murakami, K and Inoue, K and Ishizuka, M and Tanaka, T and Li, L and Sugiyama, A and Azuma, K and Murahata, Y and Tsuka, T and Ito, N and Imagawa, T and Okamoto, Y
Veterinary and Comparative Oncology, ISSN 1476-5810, 09/2017, Volume 15, Issue 3, pp. 731 - 739
5‐Aminolevulinic acid (5‐ALA) is widely used in photodynamic detection (PDD) and therapy. We evaluated the pharmacokinetics of 5‐ALA‐induced porphyrins and its... 
mammary gland tumour | 5‐aminolevulinic acid | protoporphyrin IX | dog | 5-aminolevulinic acid | INDUCED PROTOPORPHYRIN-IX | DIAGNOSIS | PORPHYRINS | THERAPY | FLUORESCENCE | ALA | AMINOLEVULINIC-ACID | PHOTOSENSITIZATION | VETERINARY SCIENCES | CARCINOMA | INVASIVE BLADDER-CANCER | Photosensitizing Agents - administration & dosage | Photosensitizing Agents - pharmacology | Animals | Spectrometry, Fluorescence - veterinary | Mammary Neoplasms, Animal - diagnosis | Administration, Oral | Aminolevulinic Acid - pharmacology | Dogs | Female | Porphyrins - metabolism | Dog Diseases - diagnosis | Aminolevulinic Acid - administration & dosage | Tumors
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13. Full Text Multifunctional theranostic contrast agent for photoacoustics- and ultrasound-based tumor diagnosis and ultrasound-stimulated local tumor therapy
by Moon, Hyungwon and Kang, Jeeun and Sim, Changbeom and Kim, Hyuncheol and Kim, Jamin and Lee, Hohyeon and Chang, Jin Ho
Journal of Controlled Release, ISSN 0168-3659, 11/2015, Volume 218, pp. 63 - 71
Biomedical imaging-guided cancer therapy should have capabilities of both accurate tumor diagnosis and high therapeutic efficacy for the personalized... 
Ultrasound-triggered release | Ultrasound | Theranostics | Photoacoustics | Local tumor treatment | TOMOGRAPHY | DRUG-DELIVERY | CAVITATION | ANTITUMOR-ACTIVITY | MICROBUBBLES | CANCER | CHEMISTRY, MULTIDISCIPLINARY | NANOPARTICLES | ALBUMIN-BOUND PACLITAXEL | IN-VIVO | PHARMACOLOGY & PHARMACY | PULSE-INVERSION | Neoplasms - metabolism | Porphyrins - administration & dosage | Theranostic Nanomedicine | Nanoparticles - chemistry | Humans | Porphyrins - chemistry | Serum Albumin - administration & dosage | Contrast Media - pharmacokinetics | Acoustics | Neoplasms - diagnosis | Paclitaxel - pharmacokinetics | Paclitaxel - chemistry | Antineoplastic Agents, Phytogenic - administration & dosage | Neoplasms - therapy | Lasers | Contrast Media - administration & dosage | Microbubbles | Female | Paclitaxel - administration & dosage | Serum Albumin - chemistry | Antineoplastic Agents, Phytogenic - pharmacokinetics | Cell Survival - drug effects | Antineoplastic Agents, Phytogenic - chemistry | Animals | Tumor Burden - drug effects | Cell Line, Tumor | Contrast Media - chemistry | Mice, Inbred BALB C | Nanoparticles - administration & dosage | Neoplasms - pathology | Chemotherapy | Ultrasound imaging | Contrast media | Cancer | Tumors
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14. Full Text Novel theranostic nanoporphyrins for photodynamic diagnosis and trimodal therapy for bladder cancer
by Lin, Tzu-Yin and Li, Yuanpei and Liu, Qiangqiang and Chen, Jui-Lin and Zhang, Hongyong and Lac, Diana and Zhang, Hua and Ferrara, Katherine W and Wachsmann-Hogiu, Sebastian and Li, Tianhong and Airhart, Susan and deVere White, Ralph and Lam, Kit S and Pan, Chong-Xian
Biomaterials, ISSN 0142-9612, 2016, Volume 104, pp. 339 - 351
Abstract The overall prognosis of bladder cancer has not been improved over the last 30 years and therefore, there is a great medical need to develop novel... 
Advanced Basic Science | Dentistry | Photothermal therapy | Photodynamic therapy | Bladder cancer | Nanotechnology | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | TUMOR | CALMETTE-GUERIN THERAPY | PROSTATE-CANCER | IN-VIVO | 5-AMINOLEVULINIC ACID | RECURRENCE | PYROPHEOPHORBIDE-A | TRANSURETHRAL RESECTION | CELL-CARCINOMA | MULTIFUNCTIONAL MICELLES | Porphyrins - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Nanoparticles - chemistry | Photochemotherapy - methods | Humans | Mice, Inbred C57BL | Treatment Outcome | Urinary Bladder Neoplasms - drug therapy | Peptides, Cyclic - administration & dosage | Photosensitizing Agents - administration & dosage | Phototherapy - methods | Animals | Theranostic Nanomedicine - methods | Microscopy, Fluorescence - methods | Urinary Bladder Neoplasms - pathology | Cell Line, Tumor | Combined Modality Therapy - methods | Mice | Nanoparticles - administration & dosage | Molecular Targeted Therapy - methods | Doxorubicin - administration & dosage | Anthracyclines | Chemotherapy | Analysis | Fluorescence | Development and progression | Photochemotherapy | Health aspects | Biomedical engineering | Cancer | nanotechnology | photodynamic therapy | photothermal therapy
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15. Full Text Targeting phosphatidylinositol 3-kinase signaling pathway for therapeutic enhancement of vascular-targeted photodynamic therapy
by Kraus, Daniel and Palasuberniam, Pratheeba and Chen, Bin
Molecular Cancer Therapeutics, ISSN 1535-7163, 11/2017, Volume 16, Issue 11, pp. 2422 - 2431
Vascular-targeted photodynamic therapy (PDT) selectively disrupts vascular function by inducing oxidative damages to the vasculature, particularly endothelial... 
CARCINOMA XENOGRAFTS | PROSTATE | PD-BACTERIOPHEOPHORBIDE TOOKAD | VERTEPORFIN | PI3K | ONCOLOGY | PANCREATIC-CANCER | TUMOR-CELLS | DRUG-RESISTANCE | PHASE I/II | INHIBITOR | Porphyrins - administration & dosage | Apoptosis - drug effects | Humans | Imidazoles - administration & dosage | Neoplasm Recurrence, Local - drug therapy | Thiazoles - administration & dosage | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Quinolines - administration & dosage | Photochemotherapy | Neovascularization, Pathologic - pathology | Neoplasm Recurrence, Local - pathology | Neoplasms - genetics | Verteporfin | Aminopyridines - administration & dosage | Morpholines - administration & dosage | Combined Modality Therapy | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Neoplasms - drug therapy | Phosphatidylinositol 3-Kinases - genetics | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors - administration & dosage | Animals | Signal Transduction - drug effects | Neovascularization, Pathologic - drug therapy | Cell Line, Tumor | Neoplasm Recurrence, Local - genetics | Neovascularization, Pathologic - genetics | Cell Proliferation - drug effects | Mice | Oxidative Stress - drug effects | Endothelial Cells - pathology | Neoplasms - pathology | Endothelial Cells - drug effects | TOR protein | Cell proliferation | Cell survival | Photodynamic therapy | Bcl-2 protein | Regrowth | Activation | Lethality | Kinases | Synergism | Mcl-1 protein | Endothelial cells | 1-Phosphatidylinositol 3-kinase | Angiogenesis | Signal transduction | Signaling | Cell activation | Inhibitors | Inhibition | Prostate | Cancer | Apoptosis
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