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Nature immunology, ISSN 1529-2908, 03/2019, Volume 20, Issue 3, pp. 288 - 300
Although tissue-resident memory T cells (TRM cells) have been shown to regulate host protection in infectious disorders, their function in inflammatory bowel... 
Transcription Factors/deficiency | Humans | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Gene Expression Profiling | Immunologic Memory/genetics | Positive Regulatory Domain I-Binding Factor 1/deficiency | Mice, Knockout | CD8-Positive T-Lymphocytes/immunology | Animals | Colitis/genetics | Cytokines/genetics | Chronic Disease | Disease Models, Animal | Inflammatory Bowel Diseases/genetics | PATHOGENESIS | IMMUNITY | ACTIVATION | CYTOKINES | THERAPY | PROTECTION | PROGRAMS | ULCERATIVE-COLITIS | INFECTION | INDUCTION | IMMUNOLOGY | Positive Regulatory Domain I-Binding Factor 1 - genetics | Colitis - genetics | Inflammatory Bowel Diseases - immunology | Transcription Factors - deficiency | Inflammatory Bowel Diseases - metabolism | Inflammatory Bowel Diseases - genetics | CD8-Positive T-Lymphocytes - metabolism | Colitis - immunology | Transcription Factors - immunology | Cytokines - genetics | Immunologic Memory - genetics | Immunologic Memory - immunology | Cytokines - immunology | Positive Regulatory Domain I-Binding Factor 1 - immunology | Cytokines - metabolism | Transcription Factors - genetics | Colitis - metabolism | Positive Regulatory Domain I-Binding Factor 1 - deficiency | CD8-Positive T-Lymphocytes - immunology | Adaptive systems | Memory cells | Inflammatory bowel diseases | Transcription factors | Animal models | Immunological memory | Pathogenesis | Mucosa | Crosstalk | Lymphocytes T | Inflammation | Tissues | CD4 antigen | Inflammatory bowel disease | CD69 antigen | CD103 antigen | Depletion | Intestine | Lymphocytes | Rodents | Colon | Colitis | Immune system
Journal Article
Science Signaling, ISSN 1945-0877, 07/2016, Volume 9, Issue 437, pp. ra73 - ra73
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 08/2016, Volume 6, Issue 1, p. 31266
Journal Article
Journal of Hematology and Oncology, ISSN 1756-8722, 06/2017, Volume 10, Issue 1, pp. 124 - 13
Background: T cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif (ITIM) domain (TIGIT) and programmed cell death protein 1 (PD-1) are... 
T cell exhaustion | TIGIT | PD-1 | Acute myeloid leukemia (AML) | Blimp-1 | TRANSCRIPTION FACTORS | AML PATIENTS | CHRONIC VIRAL-INFECTION | ANTITUMOR | CANCER-THERAPY | MEMORY | ONCOLOGY | DYSFUNCTION | HEMATOLOGY | EXPRESSION | EXHAUSTION | LYMPHOCYTES | Up-Regulation | Positive Regulatory Domain I-Binding Factor 1 - immunology | Leukemia, Myeloid, Acute - pathology | Humans | Middle Aged | Transcriptional Activation | Male | Gene Expression Regulation, Leukemic | Leukemia, Myeloid, Acute - immunology | Young Adult | T-Lymphocytes - metabolism | Adult | Female | T-Lymphocytes - immunology | Aged | T-Lymphocytes - pathology | Receptors, Immunologic - genetics | Programmed Cell Death 1 Receptor - genetics | Cytokines - immunology | Leukemia, Myeloid, Acute - genetics | Physiological aspects | Genetic aspects | Research | T cells | Apoptosis | Flow cytometry | PD-1 protein | Leukemia | Gene regulation | Cytotoxicity | Infections | Lymphocytes T | Cancer therapies | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Human immunodeficiency virus--HIV | Peripheral blood | Bone marrow | University colleges | Tyrosine | Immunoglobulins | Cytokines | Myeloid leukemia | Cloning | siRNA | Promoters | Studies | Lymphocytes B | Plasmids | Cell death | Medical prognosis | Software | Immunoreceptor tyrosine-based inhibition motif | Acute myeloid leukemia | Viral infections
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2015, Volume 195, Issue 2, pp. 488 - 497
The two best-characterized types of CD4(+) regulatory T cells (Tregs) are Foxp3(+) Tregs and Foxp3(-) 2 type 1 regulatory (Tr1) cells. The ability of Foxp3+... 
IMMUNITY | CYTOKINE PRODUCTION | MACROPHAGES | DISEASE | TRANSCRIPTION | COMPONENTS | RECEPTOR | INTERLEUKIN-10 | DIFFERENTIATION | IMMUNOLOGY | C-MAF | Forkhead Transcription Factors - immunology | Antigens, CD - immunology | NLR Family, Pyrin Domain-Containing 3 Protein | Coculture Techniques | Adoptive Transfer | Interleukin-1beta - genetics | Antigens, CD - genetics | T-Lymphocytes, Regulatory - immunology | Adenosine Triphosphate - pharmacology | Inflammasomes - drug effects | Bone Marrow Cells - immunology | T-Lymphocytes, Regulatory - cytology | Bone Marrow Cells - drug effects | Cell Differentiation | Transcription Factors - immunology | Carrier Proteins - immunology | Macrophages - immunology | Proto-Oncogene Proteins c-maf - immunology | Signal Transduction | Bone Marrow Cells - cytology | Mice, Inbred C57BL | Proto-Oncogene Proteins c-maf - genetics | Gene Expression Regulation | Receptors, Aryl Hydrocarbon - genetics | Interleukin-1beta - immunology | Mice, Transgenic | Macrophages - cytology | Transcription Factors - genetics | Forkhead Transcription Factors - genetics | Inflammasomes - genetics | Carrier Proteins - genetics | T-Lymphocytes, Regulatory - drug effects | Animals | Integrin alpha2 - genetics | Inflammasomes - immunology | Interleukin-10 - genetics | Integrin alpha2 - immunology | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Mice | Mice, Inbred BALB C | T-Lymphocytes, Regulatory - transplantation | Interleukin-10 - immunology | Receptors, Aryl Hydrocarbon - immunology | Positive Regulatory Domain I-Binding Factor 1
Journal Article
Immunity, ISSN 1074-7613, 11/2013, Volume 39, Issue 5, pp. 833 - 845
Upon infection, CD8 T cells undergo a stepwise process of early activation, expansion, and differentiation into effector cells. How these phases are... 
RESPONSES | ACTIVATION | VIRUS | IRF4 | TRANSCRIPTION | INFECTION | IMMUNOLOGY | NF-KAPPA-B | EXPRESSION | MTOR | ANTIGEN | CD8-Positive T-Lymphocytes - cytology | Cells, Cultured - cytology | Coculture Techniques | Dendritic Cells - immunology | T-Box Domain Proteins - biosynthesis | Interferon Regulatory Factors - deficiency | Bcl-2-Like Protein 11 | Interferon Regulatory Factors - physiology | Receptors, Antigen, T-Cell - immunology | TOR Serine-Threonine Kinases - physiology | Cell Differentiation | Proto-Oncogene Proteins - antagonists & inhibitors | Specific Pathogen-Free Organisms | Lymphocyte Activation | Mice, Inbred C57BL | Gene Expression Regulation | Interferon Regulatory Factors - genetics | Viral Plaque Assay | Mice, Transgenic | Transcription Factors - biosynthesis | Transcription Factors - genetics | T-Box Domain Proteins - genetics | Interferon Regulatory Factors - immunology | Animals | Membrane Proteins - antagonists & inhibitors | Apoptosis Regulatory Proteins - antagonists & inhibitors | Mice | Orthomyxoviridae Infections - virology | Orthomyxoviridae Infections - immunology | Apoptosis | Cyclin-Dependent Kinase Inhibitor Proteins - antagonists & inhibitors | Positive Regulatory Domain I-Binding Factor 1 | Transcription factors | Peptides | Lymphocytes | Rodents | T cell receptors | Infections | Expansion | Immune system
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 02/2016, Volume 17, Issue 3, pp. 323 - 330
Plasma cell differentiation requires silencing of B cell transcription, while it establishes antibody-secretory function and long-term survival. The... 
B-CELLS | MULTIPLE-MYELOMA | SURVIVAL | MESSENGER-RNA | IRF4 | BONE-MARROW | DIFFERENTIATION | IMMUNOLOGY | TRANSCRIPTION FACTOR | EXPRESSION | XBP-1 | Immunoglobulins - immunology | Activating Transcription Factor 6 - immunology | Gene Expression Profiling | Activating Transcription Factor 6 - genetics | X-Box Binding Protein 1 | Immunoglobulins - metabolism | Flow Cytometry | TOR Serine-Threonine Kinases - genetics | Chromatin Immunoprecipitation | Plasma Cells - metabolism | Transcription Factors - immunology | Microscopy, Electron, Transmission | DNA-Binding Proteins - immunology | Enzyme-Linked Immunosorbent Assay | Unfolded Protein Response - genetics | Gene Expression Regulation | Interferon Regulatory Factors - genetics | Cell Size | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Regulatory Factor X Transcription Factors | Sequence Analysis, DNA | Mice, Knockout | Cell Differentiation - immunology | TOR Serine-Threonine Kinases - immunology | Unfolded Protein Response - immunology | Interferon Regulatory Factors - immunology | Animals | High-Throughput Nucleotide Sequencing | Mice | Plasma Cells - immunology | Positive Regulatory Domain I-Binding Factor 1 | Transcription factors | Immune response | Plasma cells | Genetic aspects | Regulation | Genetic transcription | Properties | Health aspects | mTOR | unfolded protein response | transcription factor | immunoglobulin | plasma cell
Journal Article