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1. Full Text Expression of transient receptor potential ankyrin 1 (TRPA1) in the rat trigeminal sensory afferents and spinal dorsal horn
by Kim, Yun Sook and Son, Jae Youn and Kim, Tae Heon and Paik, Sang Kyoo and Dai, Yi and Noguchi, Koichi and Ahn, Dong Kuk and Bae, Yong Chul
Journal of Comparative Neurology, ISSN 0021-9967, 03/2010, Volume 518, Issue 5, pp. 687 - 698
Transient receptor potential ankyrin 1 (TRPA1), responding to noxious cold and pungent compounds, is implicated in the mediation of nociception, but little is... 
synapse | TRPA1 | trigeminal | primary afferent | Synapse | Primary afferent | Trigeminal | TRPA 1 | CORD | A-DELTA-FIBERS | ION-CHANNEL TRPA1 | NOCICEPTIVE RESPONSES | NEUROSCIENCES | PAIN | ZOOLOGY | SUBNUCLEUS INTERPOLARIS | COLD HYPERSENSITIVITY | SUBSTANTIA-GELATINOSA | NEURONS | NEUROPATHIC RATS | Immunohistochemistry | Trigeminal Nerve - metabolism | Posterior Horn Cells - metabolism | Synaptic Vesicles - metabolism | Calcium Channels - metabolism | Trigeminal Caudal Nucleus - metabolism | Dendrites - ultrastructure | Nerve Fibers, Unmyelinated - ultrastructure | Presynaptic Terminals - ultrastructure | Pain - metabolism | Microscopy, Immunoelectron | Posterior Horn Cells - cytology | Trigeminal Caudal Nucleus - cytology | Axons - ultrastructure | Sensory Receptor Cells - metabolism | Trigeminal Nuclei - metabolism | Afferent Pathways - metabolism | Biomarkers - metabolism | Dendrites - metabolism | Trigeminal Ganglion - cytology | Trigeminal Nuclei - cytology | Synaptic Vesicles - ultrastructure | TRPC Cation Channels | Axons - metabolism | Rats | Trigeminal Ganglion - metabolism | Nociceptors - cytology | Afferent Pathways - cytology | Rats, Sprague-Dawley | Animals | Sensory Receptor Cells - cytology | Nerve Fibers, Unmyelinated - metabolism | Pain - physiopathology | TRPA1 Cation Channel | Brain Mapping | Presynaptic Terminals - metabolism | Ankyrins | Substance P - metabolism | Nociceptors - metabolism | Rhizotomy | Plant Lectins - metabolism | Trigeminal Nerve - cytology
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2. Full Text Endogenous interleukin-1β in neuropathic rats enhances glutamate release from the primary afferents in the spinal dorsal horn through coupling with presynaptic N-methyl-D-aspartic acid receptors
by Yan, Xisheng and Weng, Han-Rong
Journal of Biological Chemistry, ISSN 0021-9258, 10/2013, Volume 288, Issue 42, pp. 30544 - 30557
Excessive activation of glutamate receptors and overproduction of proinflammatory cytokines, including interleukin-1 (IL-1) in the spinal dorsal horn, are key... 
NMDA RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SYNAPTIC-TRANSMISSION | Patch Clamp | SENSORY NEURONS | SUBSTANTIA-GELATINOSA NEURONS | TRANSMITTER RELEASE | Glutamate Receptors Ionotropic (AMPA | Pain | Cell Signaling | NMDA | INFLAMMATORY PAIN | LONG-TERM POTENTIATION | GROWTH-FACTOR | Glia | SCIATIC-NERVE LIGATION | ROOT GANGLION | Posterior Horn Cells - metabolism | Ceramides - metabolism | Signal Transduction | Neuralgia - metabolism | Receptors, N-Methyl-D-Aspartate - metabolism | Rats | Male | Neuralgia - pathology | Rats, Sprague-Dawley | Receptors, Interleukin-1 - metabolism | Animals | Interleukin-1beta - metabolism | Sphingomyelin Phosphodiesterase - metabolism | Posterior Horn Cells - pathology | Glutamic Acid - metabolism | Neuralgia - therapy | Myeloid Differentiation Factor 88 - metabolism | Glutamate Receptors Ionotropic (AMPA, NMDA) | Neurobiology
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3. Full Text TRPV1-Expressing Primary Afferents Generate Behavioral Responses to Pruritogens via Multiple Mechanisms
by Noritaka Imamachi and Goon Ho Park and Hyosang Lee and David J. Anderson and Melvin I. Simon and Allan I. Basbaum and Sang-Kyou Han
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2009, Volume 106, Issue 27, pp. 11330 - 11335
The mechanisms that generate itch are poorly understood at both the molecular and cellular levels despite its clinical importance. To explore the peripheral... 
Receptors | Pain | Neurons | Serotonin receptors | Mental stimulation | Nociceptors | Mice | Histamines | Behavioral neuroscience | Genotypes | Itch | PLCb3 | Scratching | C-FIBER AFFERENTS | itch | scratching | NOCICEPTORS | MULTIDISCIPLINARY SCIENCES | RECEPTOR | MICE LACKING | SPINOTHALAMIC TRACT NEURONS | PAIN | SEROTONIN | SENSATION | HISTAMINE | Posterior Horn Cells - drug effects | Posterior Horn Cells - metabolism | Serotonin - administration & dosage | Temperature | Endothelin-1 - pharmacology | Pain - metabolism | Serotonin - pharmacology | Neurons, Afferent - enzymology | TRPV Cation Channels - metabolism | Behavior, Animal - drug effects | Neurons, Afferent - drug effects | Phospholipase C beta - metabolism | Physical Stimulation | Mice, Inbred C57BL | Endothelin-1 - administration & dosage | Proto-Oncogene Proteins c-fos - metabolism | Mutation - genetics | Injections | Pruritus - metabolism | Animals | Models, Biological | Posterior Horn Cells - pathology | Serotonin - analogs & derivatives | Phospholipase C beta - deficiency | Nociceptors - metabolism | Neurons, Afferent - metabolism | Physiological aspects | Sensory receptors | Pruritus | Research | Biological Sciences
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4. Full Text The Liberation of Fractalkine in the Dorsal Horn Requires Microglial Cathepsin S
by Clark, Anna K and Yip, Ping K and Malcangio, Marzia
Journal of Neuroscience, ISSN 0270-6474, 05/2009, Volume 29, Issue 21, pp. 6945 - 6954
Understanding of the sequence and nature of the events that govern neuron-microglia communication is critical for the discovery of new mechanisms and targets... 
NEUROPATHIC PAIN | NERVE INJURY MODEL | ACTIVATED PROTEIN-KINASE | ROOT GANGLIA | NEUROTROPHIC FACTOR | P2X RECEPTORS | SPINAL MICROGLIA | TACTILE ALLODYNIA | LYSOSOMAL CYSTEINE PROTEASES | NEUROSCIENCES | RAT MODEL | Enzyme-Linked Immunosorbent Assay - methods | Microglia - metabolism | Posterior Horn Cells - drug effects | Electric Stimulation - adverse effects | Posterior Horn Cells - metabolism | Capsaicin - pharmacology | Chemokine CX3CL1 - metabolism | Sciatica - cerebrospinal fluid | Male | Phosphopyruvate Hydratase - metabolism | Rhizotomy - methods | RNA, Messenger - metabolism | Sulfones - pharmacology | DNA-Binding Proteins - metabolism | Lumbosacral Region | Spinal Cord - pathology | Behavior, Animal - drug effects | p38 Mitogen-Activated Protein Kinases - metabolism | Calcitonin Gene-Related Peptide - metabolism | Cathepsins - antagonists & inhibitors | Disease Models, Animal | Microglia - drug effects | Sciatica - pathology | Interleukin-1beta - cerebrospinal fluid | Rats | Behavior, Animal - physiology | Chemokine CX3CL1 - genetics | Functional Laterality | Gene Expression Regulation - drug effects | Animals | Analysis of Variance | Cathepsins - genetics | Cathepsins - metabolism | Lipopolysaccharides - pharmacology | In Vitro Techniques
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5. Full Text Persistent Inflammation Induces GluR2 Internalization via NMDA Receptor-Triggered PKC Activation in Dorsal Horn Neurons
by Park, Jang-Su and Voitenko, Nana and Petralia, Ronald S and Guan, Xiaowei and Xu, Ji-Tian and Steinberg, Jordan P and Takamiya, Kogo and Sotnik, Andrij and Kopach, Olga and Huganir, Richard L and Tao, Yuan-Xiang
Journal of Neuroscience, ISSN 0270-6474, 03/2009, Volume 29, Issue 10, pp. 3206 - 3219
Spinal cord GluR2-lacking AMPA receptors (AMPARs) contribute to nociceptive hypersensitivity in persistent pain, but the molecular mechanisms underlying this... 
GLUTAMATE-RECEPTOR | PROTEIN-KINASE | PDZ DOMAIN | LONG-TERM DEPRESSION | KINASE-C-ALPHA | CA2+-PERMEABLE AMPA RECEPTORS | SPINAL-CORD | LAMINAE-I-III | SYNAPTIC PLASTICITY | NEUROSCIENCES | COMPLETE FREUNDS-ADJUVANT | Inflammation - pathology | Posterior Horn Cells - metabolism | Receptors, N-Methyl-D-Aspartate - metabolism | Rats | Male | Rats, Sprague-Dawley | Inflammation - metabolism | Animals | Time Factors | Mice, Mutant Strains | Protein Kinase C - metabolism | Posterior Horn Cells - pathology | Female | Posterior Horn Cells - enzymology | Mice | Enzyme Activation - physiology | Receptors, AMPA - metabolism
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6. Full Text VPS26A-SNX27 interaction-dependent MGLUR5 recycling in dorsal horn neurons mediates neuropathic pain in rats
by Lin, Tzer-Bin and Lai, Cheng-Yuan and Hsieh, Ming-Chun and Wang, Hsueh-Hsiao and Cheng, Jen-Kun and Chau, Yat-Pang and Chen, Gin-Den and Peng, Hsien-Yu
Journal of Neuroscience, ISSN 0270-6474, 11/2015, Volume 35, Issue 44, pp. 14943 - 14955
Retromer, which crucially contributes to endosomal sorting machinery through the retrieval and recycling of signaling receptors away from degradation, has been... 
Allodynia | SNX27 | VPS26 | MGluR5 | Retromer | Neuropathic pain | RECRUITMENT | RECOGNITION | PHOSPHORYLATION | PDZ DOMAIN | TRAFFICKING | SYNAPTIC PLASTICITY | NEUROSCIENCES | neuropathic pain | allodynia | retromer | SPINAL NERVE LIGATION | DEGRADATION | RECEPTORS | mGluR5 | Posterior Horn Cells - metabolism | Vesicular Transport Proteins - metabolism | Neuralgia - metabolism | Rats | Male | Neuralgia - pathology | Receptor, Metabotropic Glutamate 5 - metabolism | Rats, Sprague-Dawley | Nerve Tissue Proteins - metabolism | Pain Measurement - methods | Animals | Posterior Horn Cells - pathology | Protein Binding - physiology
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7. Full Text Functional heterogeneity of calretinin‐expressing neurons in the mouse superficial dorsal horn: implications for spinal pain processing
by Smith, K. M and Boyle, K. A and Madden, J. F and Dickinson, S. A and Jobling, P and Callister, R. J and Hughes, D. I and Graham, B. A
The Journal of Physiology, ISSN 0022-3751, 10/2015, Volume 593, Issue 19, pp. 4319 - 4339
Neurons in the superficial dorsal horn (SDH) of the spinal cord play an important role in nociceptive, thermal, itch and light touch sensations. Excitatory... 
SUBSTANTIA-GELATINOSA NEURONS | LAMINA-II | INHIBITORY INTERNEURONS | GREEN FLUORESCENT PROTEIN | IN-VITRO | PRIMARY AFFERENTS | PHYSIOLOGY | ELECTROPHYSIOLOGICAL FEATURES | PATCH-CLAMP ANALYSIS | EXCITATORY INTERNEURONS | NEUROSCIENCES | TRANSGENIC MICE | Posterior Horn Cells - metabolism | Calbindin 2 - metabolism | Mice, Inbred C57BL | Male | Mice, Transgenic | Animals | Calbindin 2 - physiology | Membrane Potentials | Pain - physiopathology | Female | Mice | Calbindin 2 - genetics | Posterior Horn Cells - physiology | Neurons | Genetic engineering | Protein binding | Population | Spinal cord | Rodents | Neuroscience ‐ Cellular | Molecular | Research Paper
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8. Full Text Delayed activation of spinal microglia contributes to the maintenance of bone cancer pain in female Wistar rats via P2X7 receptor and IL-18
by Yang, Yan and Li, Hui and Li, Ting-Ting and Luo, Hao and Gu, Xi-Yao and Lü, Ning and Ji, Ru-Rong and Zhang, Yu-Qiu
Journal of Neuroscience, ISSN 0270-6474, 2015, Volume 35, Issue 20, pp. 7950 - 7963
Accumulating evidence suggests that activation of spinal microglia contributes to the development of inflammatory and neuropathic pain. However, the role of... 
Female rats | Neuron-glial interaction | Bone cancer pain | P2X7 receptor | IL-18 | Microglia | female rats | neuron-glial interaction | bone cancer pain | microglia | NEUROSCIENCES | Microglia - metabolism | Posterior Horn Cells - metabolism | Rats, Wistar | Minocycline - pharmacology | Neuralgia - metabolism | Adenosine Triphosphate - cerebrospinal fluid | Rats | Bone Neoplasms - complications | Neuralgia - drug therapy | Receptors, Purinergic P2X7 - genetics | Animals | Microglia - physiology | Excitatory Postsynaptic Potentials | Miniature Postsynaptic Potentials | Minocycline - therapeutic use | Neuralgia - etiology | Receptors, Purinergic P2X7 - metabolism | Female | p38 Mitogen-Activated Protein Kinases - metabolism | Neuralgia - physiopathology | Posterior Horn Cells - physiology | Interleukin-18 - genetics | Interleukin-18 - metabolism
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9. Full Text Ionotropic and Metabotropic Receptors, Protein Kinase A, Protein Kinase C, and Src Contribute to C-Fiber-Induced ERK Activation and cAMP Response Element-Binding Protein Phosphorylation in Dorsal Horn Neurons, Leading to Central Sensitization
by Kawasaki, Yasuhiko and Kohno, Tatsuro and Zhuang, Zhi-Ye and Brenner, Gary J and Wang, Haibin and Van Der Meer, Catrien and Befort, Katia and Woolf, Clifford J and Ji, Ru-Rong
Journal of Neuroscience, ISSN 0270-6474, 09/2004, Volume 24, Issue 38, pp. 8310 - 8321
Molecular mechanisms underlying C-fiber stimulation-induced ERK ( extracellular signal-regulated kinase) activation in dorsal horn neurons and its contribution... 
CREB | Pain | Capsaicin | C-fiber | Spinal cord slices | Dorsal horn | ERK | RAT SPINAL-CORD | pain | NMDA RECEPTOR | dorsal horn | INFLAMMATORY PAIN HYPERSENSITIVITY | MAP KINASE | NEUROTROPHIC FACTOR | spinal cord slices | INTRADERMAL INJECTION | SYNAPTIC PLASTICITY | NEUROSCIENCES | NUCLEAR TRANSLOCATION | TRANSCRIPTION FACTOR CREB | capsaicin | LONG-TERM POTENTIATION | Hyperalgesia - chemically induced | Receptors, Glutamate - metabolism | Posterior Horn Cells - metabolism | Electric Stimulation | Extracellular Signal-Regulated MAP Kinases - drug effects | Male | Substance P - pharmacology | Extracellular Signal-Regulated MAP Kinases - metabolism | N-Methylaspartate - pharmacology | Brain-Derived Neurotrophic Factor - pharmacology | Protein Kinase C - metabolism | src-Family Kinases - metabolism | Posterior Horn Cells - enzymology | Phosphorylation - drug effects | Organ Culture Techniques | Cyclic AMP-Dependent Protein Kinases - metabolism | Nerve Fibers, Unmyelinated - enzymology | Hyperalgesia - metabolism | Rats | Pain Measurement - drug effects | Enzyme Activation - drug effects | Rats, Sprague-Dawley | Stimulation, Chemical | Animals | Nerve Fibers, Unmyelinated - metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Hyperalgesia - etiology | Enzyme Activation - physiology | Plasticity | Development | Repair
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10. Full Text Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents
by Burma, Nicole E and Bonin, Robert P and Leduc-Pessah, Heather and Baimel, Corey and Cairncross, Zoe F and Mousseau, Michael and Shankara, Jhenkruthi Vijaya and Stemkowski, Patrick L and Baimoukhametova, Dinara and Bains, Jaideep S and Antle, Michael C and Zamponi, Gerald W and Cahill, Catherine M and Borgland, Stephanie L and De Koninck, Yves and Trang, Tuan
Nature Medicine, ISSN 1078-8956, 03/2017, Volume 23, Issue 3, pp. 355 - 360
Opiates are essential for treating pain, but termination of opiate therapy can cause a debilitating withdrawal syndrome in chronic users. To alleviate or avoid... 
MEDICINE, RESEARCH & EXPERIMENTAL | CHRONIC PAIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | PORE FORMATION | DORSAL-HORN | VENTRAL TEGMENTAL AREA | DEPENDENCE | CELL BIOLOGY | HEMICHANNELS | ATP RELEASE | OPIOID WITHDRAWAL | BEHAVIORS | Connexins - antagonists & inhibitors | Microglia - metabolism | Posterior Horn Cells - drug effects | Posterior Horn Cells - metabolism | Substance Withdrawal Syndrome - etiology | Coculture Techniques | Narcotics - adverse effects | Substance Withdrawal Syndrome - metabolism | Apyrase - pharmacology | Adenosine Triphosphate - metabolism | Nociception - drug effects | Substance Withdrawal Syndrome - genetics | Behavior, Animal - drug effects | Neurons - metabolism | Cell Culture Techniques | Neurons - drug effects | Mefloquine - pharmacology | Nerve Tissue Proteins - antagonists & inhibitors | Microglia - drug effects | Probenecid - pharmacology | Connexins - genetics | Narcotic Antagonists - adverse effects | Rats | Nerve Tissue Proteins - genetics | Blotting, Western | Connexins - metabolism | Nerve Tissue Proteins - metabolism | Animals | Naloxone - pharmacology | Mice | Morphine - adverse effects | Care and treatment | Drug withdrawal symptoms | Physiological aspects | Morphine | Models | Properties | Membrane proteins
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11. Full Text Loss of GABAergic interneurons in laminae I-III of the spinal cord dorsal horn contributes to reduced GABAergic tone and neuropathic pain after spinal cord injury
by Meisner, Jason G and Marsh, Adam D and Marsh, Daniel R
Journal of Neurotrauma, ISSN 0897-7151, 04/2010, Volume 27, Issue 4, pp. 729 - 737
In this study we explore if loss of GABAergic inhibitory interneurons in the superficial dorsal horn of the spinal cord contributes to reduced GABAergic tone... 
Allodynia | Glutamate decarboxylase | GABA transporter | Thermal hyperalgesia | γ-aminobutyric acid | thermal hyperalgesia | RAT | TACTILE ALLODYNIA | gamma-aminobutyric acid | NEUROSCIENCES | CLINICAL NEUROLOGY | PERIPHERAL-NERVE INJURY | allodynia | GREEN FLUORESCENT PROTEIN | 2 FORMS | ANION GRADIENT | CONTUSION INJURY | GABA | NEURONS | GLUTAMATE-DECARBOXYLASE | glutamate decarboxylase | CRITICAL CARE MEDICINE | Pain Threshold - physiology | Posterior Horn Cells - metabolism | Spinal Cord Injuries - complications | Cell Count | Caspase 3 - metabolism | Nerve Degeneration - physiopathology | Neuralgia - metabolism | Apoptosis - genetics | Male | Green Fluorescent Proteins - genetics | Promoter Regions, Genetic - genetics | Nerve Degeneration - metabolism | GABA Plasma Membrane Transport Proteins - metabolism | Neuralgia - etiology | Neuralgia - physiopathology | Nipecotic Acids - pharmacology | GABA Uptake Inhibitors | Disease Models, Animal | Neural Inhibition - genetics | Green Fluorescent Proteins - metabolism | Spinal Cord Injuries - metabolism | Glutamate Decarboxylase - genetics | Mice, Transgenic | Down-Regulation - genetics | Interneurons - pathology | Animals | Interneurons - metabolism | gamma-Aminobutyric Acid - deficiency | GABA Agonists - pharmacology | Posterior Horn Cells - pathology | Glutamate Decarboxylase - metabolism | Mice | Spinal Cord Injuries - physiopathology | Nerve Degeneration - etiology | Pain Measurement | Neural Inhibition - drug effects | Physiological aspects | Care and treatment | Spinal cord injuries | Neurons | Patient outcomes | Neurotransmitters | Pain | Cellular biology
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12. Full Text Heteromeric α/β glycine receptors regulate excitability in parvalbumin‐expressing dorsal horn neurons through phasic and tonic glycinergic inhibition
by Gradwell, M. A and Boyle, K. A and Callister, R. J and Hughes, D. I and Graham, B. A
The Journal of Physiology, ISSN 0022-3751, 12/2017, Volume 595, Issue 23, pp. 7185 - 7202
Spinal parvalbumin‐expressing interneurons have been identified as a critical source of inhibition to regulate sensory thresholds by gating mechanical inputs... 
inhibition | pain | glycine receptors | extrasynaptic receptors | dorsal horn | Nociception | Posterior Horn Cells - drug effects | Posterior Horn Cells - metabolism | Parvalbumins - metabolism | Male | Glycine Agents - pharmacology | Animals | Glycine - pharmacology | Receptors, GABA - metabolism | Parvalbumins - genetics | Female | Mice | Mice, Inbred BALB C | Receptors, Glycine - metabolism | Inhibitory Postsynaptic Potentials | Posterior Horn Cells - physiology | Receptors, Glycine - genetics | Research Paper | Neuroscience ‐ Cellular | Molecular
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13. Full Text Loss of Inhibitory Interneurons in the Dorsal Spinal Cord and Elevated Itch in Bhlhb5 Mutant Mice
by Ross, Sarah E and Mardinly, Alan R and McCord, Alejandra E and Zurawski, Jonathan and Cohen, Sonia and Jung, Cynthia and Hu, Linda and Mok, Stephanie I and Shah, Anar and Savner, Erin M and Tolias, Christos and Corfas, Gabriel and Corfas, Roman and Chen, Suzhen and Inquimbert, Perrine and Xu, Yi and McInnes, Roderick R and Rice, Frank L and Ma, Qiufu and Woolf, Clifford J and Greenberg, Michael E
Neuron, ISSN 0896-6273, 03/2010, Volume 65, Issue 6, pp. 886 - 898
Itch is the least well understood of all the somatic senses, and the neural circuits that underlie this sensation are poorly defined. Here we show that the... 
DEVBIO | MOLNEURO | Devbio | Molneuro | PERIPHERAL-NERVE INJURY | SCRATCHING BEHAVIOR | RESPONSES | CENTRAL SENSITIZATION | HORN | SPINOTHALAMIC TRACT NEURONS | GABAERGIC INHIBITION | PAIN HYPERSENSITIVITY | FORMALIN TEST | RECEPTORS | NEUROSCIENCES | Basic Helix-Loop-Helix Transcription Factors - physiology | Posterior Horn Cells - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Spinal Cord - metabolism | Pruritus - genetics | Interneurons - pathology | Mice, Neurologic Mutants | Mice, Knockout | Pruritus - physiopathology | Neural Inhibition - physiology | Animals | Interneurons - metabolism | Spinal Cord - pathology | Posterior Horn Cells - pathology | Mice | Pruritus - pathology | Gene Knock-In Techniques - methods | Basic Helix-Loop-Helix Transcription Factors - deficiency | Cell Survival - physiology | Neurosciences | Molecular genetics | Developmental biology | Neurons | Children's hospitals | Studies | Spinal cord | Transcription factors | Pain | Rodents | Skin | Behavior
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14. Full Text Involvement of spinal IL-6 trans-signaling in the induction of hyperexcitability of deep dorsal horn neurons by spinal tumor necrosis factor-alpha
by König, Christian and Morch, Eric and Eitner, Annett and Möller, Christian and Turnquist, Brian and Schaible, Hans-Georg and Ebersberger, Andrea
Journal of Neuroscience, ISSN 0270-6474, 09/2016, Volume 36, Issue 38, pp. 9782 - 9791
During peripheral inflammation, both spinal TNF-alpha and IL-6 are released within the spinal cord and support the generation of inflammation-evoked spinal... 
Central sensitization | Electrophysiology | Soluble IL-6 receptor | Inflammation | Cytokine | Microglia | cytokine | CORD | CHRONIC PAIN | GLIAL ACTIVATION | central sensitization | RECEPTOR | SOLUBLE IL-6 | NEUROSCIENCES | NEUROPATHIC PAIN | MECHANICAL STIMULI | electrophysiology | soluble IL-6 receptor | BRAIN ISCHEMIA | inflammation | INTERLEUKIN-6 MESSENGER-RNA | TNF-ALPHA | microglia | Microglia - metabolism | Posterior Horn Cells - drug effects | Posterior Horn Cells - metabolism | Spinal Cord - drug effects | Spinal Cord - metabolism | Rats, Wistar | Minocycline - pharmacology | Male | Glial Fibrillary Acidic Protein - metabolism | Time Factors | Ubiquitin Thiolesterase - metabolism | Microfilament Proteins - metabolism | Spinal Cord - cytology | Interleukin-6 - metabolism | Action Potentials - drug effects | Calcium-Binding Proteins - metabolism | Physical Stimulation | Cytokine Receptor gp130 - metabolism | Microglia - drug effects | Rats | Tumor Necrosis Factor-alpha - pharmacology | Animals | Signal Transduction - drug effects | Cell Line, Tumor | Mice
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15. Full Text Imaging large-scale cellular activity in spinal cord of freely behaving mice
by Sekiguchi, Kohei J and Shekhtmeyster, Pavel and Merten, Katharina and Arena, Alexander and Cook, Daniela and Hoffman, Elizabeth and Ngo, Alexander and Nimmerjahn, Axel
Nature communications, ISSN 2041-1723, 04/2016, Volume 7, Issue 1, p. 11450
Sensory information from mechanoreceptors and nociceptors in the skin plays key roles in adaptive and protective motor behaviours. To date, very little is... 
Motor Activity - physiology | Posterior Horn Cells - metabolism | Spinal Cord - metabolism | Calcium - metabolism | Mice, Inbred C57BL | Mechanoreceptors - physiology | Nociceptors - physiology | Mice, Transgenic | Microscopy, Confocal | Astrocytes - physiology | Animals | Posterior Horn Cells - cytology | Spinal Cord - physiology | Neurons - physiology | Neurons - metabolism | Spinal Cord - cytology | Posterior Horn Cells - physiology | Astrocytes - metabolism
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