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Journal Article
PloS one, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, pp. e0180154 - e0180154
Ion channels regulate a variety of physiological processes and represent an important class of drug target... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cricetulus | High-Throughput Screening Assays - instrumentation | NAV1.3 Voltage-Gated Sodium Channel - genetics | NAV1.1 Voltage-Gated Sodium Channel - genetics | NAV1.5 Voltage-Gated Sodium Channel - metabolism | NAV1.1 Voltage-Gated Sodium Channel - metabolism | NAV1.4 Voltage-Gated Sodium Channel - metabolism | Kv1.3 Potassium Channel - genetics | NAV1.2 Voltage-Gated Sodium Channel - metabolism | NAV1.3 Voltage-Gated Sodium Channel - metabolism | Patch-Clamp Techniques - methods | Kv1.3 Potassium Channel - deficiency | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | Sodium Channels - metabolism | NAV1.7 Voltage-Gated Sodium Channel - genetics | NAV1.5 Voltage-Gated Sodium Channel - genetics | Drug Evaluation, Preclinical | Transgenes | Potassium Channel Blockers - pharmacology | CHO Cells | High-Throughput Screening Assays - methods | Gene Expression | NAV1.4 Voltage-Gated Sodium Channel - genetics | NAV1.2 Voltage-Gated Sodium Channel - genetics | Rats | Sodium Channel Blockers - pharmacology | Membrane Potentials - physiology | Animals | T-Lymphocytes - cytology | NAV1.6 Voltage-Gated Sodium Channel - metabolism | NAV1.7 Voltage-Gated Sodium Channel - metabolism | NAV1.6 Voltage-Gated Sodium Channel - genetics | Sodium Channels - genetics | Primary Cell Culture | Patch-Clamp Techniques - instrumentation | Ion channels | Information management | Drug discovery | T cells | Modules | Electrophysiology | Patching | Lymphocytes T | Boundaries | Assaying | Channels | Step voltage | Immunology | Pain | Lymphocytes | Sodium channels (voltage-gated) | Physiology | Potassium channels (voltage-gated) | Gold | Platforms | Data points | Automation | Cloning | Pharmacology | Sodium | Antigen-presenting cells | Ligands | Mutation | Recording | Potassium | Index Medicus
Journal Article
by Perry, John R. B and Day, Felix and Elks, Cathy E and Sulem, Patrick and Thompson, Deborah J and Ferreira, Teresa and He, Chunyan and Chasman, Daniel I and Esko, Tõnu and Thorleifsson, Gudmar and Albrecht, Eva and Ang, Wei Q and Corre, Tanguy and Cousminer, Diana L and Feenstra, Bjarke and Franceschini, Nora and Ganna, Andrea and Johnson, Andrew D and Kjellqvist, Sanela and Lunetta, Kathryn L and McMahon, George and Nolte, Ilja M and Paternoster, Lavinia and Porcu, Eleonora and Smith, Albert V and Stolk, Lisette and Teumer, Alexander and Tšernikova, Natalia and Tikkanen, Emmi and Ulivi, Sheila and Wagner, Erin K and Amin, Najaf and Bierut, Laura J and Byrne, Enda M and Hottenga, Jouke-Jan and Koller, Daniel L and Mangino, Massimo and Pers, Tune H and Yerges-Armstrong, Laura M and Hua Zhao, Jing and Andrulis, Irene L and Anton-Culver, Hoda and Atsma, Femke and Bandinelli, Stefania and Beckmann, Matthias W and Benitez, Javier and Blomqvist, Carl and Bojesen, Stig E and Bolla, Manjeet K and Bonanni, Bernardo and Brauch, Hiltrud and Brenner, Hermann and Buring, Julie E and Chang-Claude, Jenny and Chanock, Stephen and Chen, Jinhui and Chenevix-Trench, Georgia and Collée, J. Margriet and Couch, Fergus J and Couper, David and Coviello, Andrea D and Cox, Angela and Czene, Kamila and D’adamo, Adamo Pio and Davey Smith, George and De Vivo, Immaculata and Demerath, Ellen W and Dennis, Joe and Devilee, Peter and Dieffenbach, Aida K and Dunning, Alison M and Eiriksdottir, Gudny and Eriksson, Johan G and Fasching, Peter A and Ferrucci, Luigi and Flesch-Janys, Dieter and Flyger, Henrik and Foroud, Tatiana and Franke, Lude and Garcia, Melissa E and García-Closas, Montserrat and Geller, Frank and de Geus, Eco E. J and Giles, Graham G and Gudbjartsson, Daniel F and Gudnason, Vilmundur and Guénel, Pascal and Guo, Suiqun and Hall, Per and Hamann, Ute and Haring, Robin and Hartman, Catharina A and Heath, Andrew C and Hofman, Albert and Hooning, Maartje J and Hopper, John L and Hu, Frank B and Hunter, David J and Karasik, David and Kiel, Douglas P and ... and Australian Ovarian Cancer Study and kConFab and Early Growth Genetics (EGG) Consortium and The GENICA Network and The InterAct Consortium and The LifeLines Cohort Study and kConFabt LifeLines Cohort Study and InterAct Consortium and Australian Ovarian Canc Study and Early Growth Genetics EGG Consorti and GENICA Network and LifeLines Cohort Study
Nature (London), ISSN 1476-4687, 07/2014, Volume 514, Issue 7520, pp. 92 - 97
Journal Article
PloS one, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, pp. e0133037 - e0133037
.... Genetic variation is identified and associated with 30-35% of cases of Brugada Syndrome, with nearly 20-25... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Brugada Syndrome - genetics | Brugada Syndrome - diagnosis | Genetic Testing | Cytoskeletal Proteins - genetics | Humans | Middle Aged | Male | Calsequestrin - genetics | Death, Sudden, Cardiac | Genetic Variation | A Kinase Anchor Proteins - genetics | gamma Catenin | Desmoplakins - genetics | Clinical Decision-Making | Adult | Female | Retrospective Studies | NAV1.5 Voltage-Gated Sodium Channel - genetics | Arrhythmias, Cardiac - genetics | Desmoglein 2 - genetics | Penetrance | Potassium Channels, Inwardly Rectifying - genetics | Sequence Analysis, DNA | Ryanodine Receptor Calcium Release Channel - genetics | Pedigree | Ankyrins - genetics | High-Throughput Nucleotide Sequencing | Cohort Studies | Cardiac arrhythmia | Copy number | Genes | Insertion | Ryanodine receptors | Genetic screening | Gene sequencing | Complexity | Proteins | Defibrillators | Genetic analysis | Electrocardiography | Potassium channels (voltage-gated) | Heart diseases | Ion channels (cyclic nucleotide-gated) | Potassium channels (inwardly-rectifying) | Decision making | Data processing | Genetic diversity | Patients | Coronary artery disease | Substrates | Diseases | Genetic variance | KCNQ1 protein | Mutation | Variation | Index Medicus | Malalties | Heart | Aspectes genètics | Arítmia | Arrhythmia | Cor | Genetic aspects
Journal Article
Nature genetics, ISSN 1546-1718, 03/2009, Volume 41, Issue 4, pp. 399 - 406
Journal Article