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European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 11/2013, Volume 85, Issue 3, pp. 604 - 613
In a number of pulmonary diseases, patients may develop abnormally viscous mucus reducing drug efficacy. To increase budesonide diffusion within lung fluid, we... 
Dry powder inhaler | Budesonide | Nanoporous microparticles | Ambroxol | Calu-3 cells | Andersen cascade impactor | PARTICLES | COMBINATION THERAPY | BARRIER | INHALED CORTICOSTEROIDS | DRY POWDER INHALATION | FORMULATION | IN-VITRO | PHARMACOLOGY & PHARMACY | CELL-CULTURE | Cell Line | Dry Powder Inhalers | Epithelial Cells - metabolism | Bronchodilator Agents - administration & dosage | Humans | Administration, Inhalation | Ambroxol - pharmacokinetics | Permeability | Chemistry, Pharmaceutical | Drug Delivery Systems | Microspheres | Expectorants - pharmacokinetics | Bronchodilator Agents - pharmacokinetics | Expectorants - administration & dosage | Ambroxol - administration & dosage | Drug Compounding | Lung - metabolism | Budesonide - administration & dosage | Porosity | Respiratory Mucosa - metabolism | Diffusion | Bronchi - cytology | Budesonide - pharmacokinetics | Drugs | Respiratory agents | Drug delivery systems | Vehicles | Index Medicus | Ambroxol/pharmacokinetics | Expectorants/administration & dosage | Life Sciences | Budesonide/administration & dosage | Expectorants/pharmacokinetics | Budesonide/pharmacokinetics | Bronchodilator Agents/administration & dosage | Pharmaceutical sciences | Administration | Epithelial Cells/metabolism | Lung/metabolism | Pharmaceutical | Inhalation | Chemistry | Bronchodilator Agents/pharmacokinetics | Bronchi/cytology | Respiratory Mucosa/metabolism | Ambroxol/administration & dosage
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 02/2013, Volume 83, Issue 2, pp. 174 - 183
This work describes the effect of polymeric microcarriers on the intra- nasal uptake of azolmitriptan for brain targeting. Moreover, the suitability of... 
Nasal administration | Microspheres | Brain targeting | Chitosan | Zolmitriptan | In vivo studies | MUCOADHESIVE MICROSPHERES | DELIVERY-SYSTEMS | CHITOSAN-GLUTAMATE | CEREBROSPINAL-FLUID | RAT MODEL | NASAL ABSORPTION | PHARMACOLOGY & PHARMACY | BIOADHESIVE FORMULATIONS | SUBMICRON EMULSION | HEALTHY-VOLUNTEERS | Polymers - administration & dosage | Chemistry, Pharmaceutical - methods | Hypromellose Derivatives - chemistry | Area Under Curve | Drug Carriers - administration & dosage | Oxazolidinones - administration & dosage | Drug Carriers - chemistry | Adhesives - chemistry | Oxazolidinones - chemistry | Adhesives - administration & dosage | Administration, Intranasal - methods | Swine | Nasal Mucosa - drug effects | Powders - administration & dosage | Tryptamines - chemistry | Chitosan - administration & dosage | Hypromellose Derivatives - administration & dosage | Permeability | Migraine Disorders - drug therapy | Brain - drug effects | Powders - chemistry | Glutamic Acid - administration & dosage | Animals | Chitosan - chemistry | Administration, Intravenous - methods | Glutamic Acid - chemistry | Tryptamines - administration & dosage | Glutamate | Index Medicus | Annan hälsovetenskap | Health Science | Hälsovetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Other Health Sciences | Hälsovetenskaper | Health Sciences
Journal Article
Chest, ISSN 0012-3692, 02/2006, Volume 129, Issue 2, pp. 246 - 256
Study objective: To compare a novel asthma management strategy-budesonide/formoterol in a single inhaler for both maintenance therapy and symptom relief-with a... 
Budesonide/formoterol | Inhaled corticosteroids | Asthma | LONG-TERM | SALBUTAMOL | ADULTS | PERSISTENT ASTHMA | asthma | TURBUHALER(R) | FORMOTEROL | RESPIRATORY SYSTEM | TOLERABILITY | EXACERBATIONS | TERBUTALINE | LOW-DOSE BUDESONIDE | budesonide/formoterol | inhaled corticosteroids | CRITICAL CARE MEDICINE | Formoterol Fumarate | Glucocorticoids - administration & dosage | Bronchodilator Agents - administration & dosage | Humans | Middle Aged | Male | Ethanolamines - administration & dosage | Forced Expiratory Volume | Terbutaline - administration & dosage | Aged, 80 and over | Adult | Female | Drug Therapy, Combination | Child | Powders | Asthma - physiopathology | Double-Blind Method | Administration, Inhalation | Asthma - drug therapy | Adolescent | Aged | Budesonide - administration & dosage | Peak Expiratory Flow Rate | Drug Combinations | Nebulizers and Vaporizers | Care and treatment | Patients | Methods | Index Medicus | Abridged Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap | Asthma/drug therapy/physiopathology | Ethanolamines/administration & dosage | Klinisk medicin | MEDICINE | Budesonide/administration & dosage | Aged; 80 and over | Drug Therapy; Combination | Research Support; Non-U.S. Gov't | Lungmedicin och allergi | Invärtesmedicin | Dermatologi och venerologi, klinisk genetik, invärtesmedicin | Respiratory Medicine and Allergy | Bronchodilator Agents/administration & dosage | Lungsjukdomar | Internal medicine | Lung diseases | Dermatology and venerology,clinical genetics, internal medicine | Administration; Inhalation | Clinical Medicine | Terbutaline/administration & dosage | MEDICIN | Glucocorticoids/administration & dosage
Journal Article
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 9/2011, Volume 28, Issue 9, pp. 2157 - 2164
Journal Article
Journal Article
Journal Article
Journal of Chromatography B, ISSN 1570-0232, 01/2018, Volume 1072, pp. 282 - 289
YiQiFuMai powder injection (YQFM), derived from the classical traditional Chinese medicine (TCM) formula Shengmai San, is a modern preparation widely used to... 
UFLC–MS/MS | Chronic heart failure | Pharmacokinetics | YiQiFuMai powder injection | Ginsenosides | BARRIER DYSFUNCTION | CHEMISTRY, ANALYTICAL | PLASMA | BIOCHEMICAL RESEARCH METHODS | INJURY | UFLC-MS/MS | NF-KAPPA-B | Heart failure | Powders | Ionization | Formic acid | Nitriles | Liquid chromatography | Mass spectrometry | Organic acids | Index Medicus
Journal Article
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 12/2007, Volume 176, Issue 11, pp. 1138 - 1145
Rationale: Nitric oxide-independent agonists of soluble guanylate cyclase (sGC) have been developed. Objectives: We tested whether inhalation of novel... 
BAY 41-2272 | BAY 58-2667 | Pulmonary hypertension | BAY 41-8543 | Soluble guanylate cyclase | LARGE POROUS PARTICLES | AUGMENTS | pulmonary hypertension | INHALATION | soluble guanylate cyclase | DELIVERY | INHIBITION | ACTIVATOR | RESPIRATORY SYSTEM | BAY-41-2272 | NITRIC-OXIDE | AWAKE LAMBS | HYPERTENSION | CRITICAL CARE MEDICINE | Oxadiazoles - administration & dosage | Injections, Intravenous | Nitric Oxide - pharmacology | Purinones - administration & dosage | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Oxadiazoles - pharmacology | Lung - metabolism | Pyrazoles - pharmacology | Powders | Pyridines - administration & dosage | Quinoxalines - administration & dosage | Pyrimidines - administration & dosage | Morpholines - administration & dosage | Administration, Inhalation | Morpholines - pharmacology | Phosphodiesterase Inhibitors - pharmacology | Soluble Guanylyl Cyclase | Receptors, Cytoplasmic and Nuclear - agonists | Pyrimidines - pharmacology | Nitric Oxide - administration & dosage | Benzoates - administration & dosage | Particle Size | Phosphodiesterase Inhibitors - administration & dosage | Pyrazoles - administration & dosage | Animals | Cyclic GMP - metabolism | Guanylate Cyclase | Lung - drug effects | Aerosols | Benzoates - pharmacology | Purinones - pharmacology | Sheep | Pulmonary Circulation - drug effects | Pyridines - pharmacology | Vasodilation - drug effects | Drug Combinations | Index Medicus | Abridged Index Medicus | H. Pulmonary Vascular Disease
Journal Article
Phytotherapy Research, ISSN 0951-418X, 12/2018, Volume 32, Issue 12, pp. 2408 - 2416
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2012, Volume 157, Issue 1, pp. 149 - 159
Although few experimental studies have been handled so far to exploit the potential of poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) in the... 
Nanoparticles | PLGA | Dry powders | Antibiotics | Pulmonary delivery |