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1. Full Text Efficacy of HPV-based screening for prevention of invasive cervical cancer: follow-up of four European randomised controlled trials
by Ronco, Guglielmo, Dr and Dillner, Joakim, Prof and Elfström, K Miriam, MPH and Tunesi, Sara, PhD and Snijders, Peter J F, Prof and Arbyn, Marc, MD and Kitchener, Henry, Prof and Segnan, Nereo, MD and Gilham, Clare, MSc and Giorgi-Rossi, Paolo, PhD and Berkhof, Johannes, PhD and Peto, Julian, Prof and Meijer, Chris J L M, Prof and Int HPV Screening Working Grp and International HPV screening working group
Lancet, The, ISSN 0140-6736, 2014, Volume 383, Issue 9916, pp. 524 - 532
Summary Background In four randomised trials, human papillomavirus (HPV)-based screening for cervical cancer was compared with cytology-based cervical... 
Internal Medicine | LIQUID-BASED CYTOLOGY | RECRUITMENT | WOMEN | TESTS | MEDICINE, GENERAL & INTERNAL | HIGH-RISK | PERSISTENCE | IMPLEMENTATION | HUMAN-PAPILLOMAVIRUS DNA | INTRAEPITHELIAL NEOPLASIA | POBASCAM | Early Detection of Cancer - standards | Precancerous Conditions - epidemiology | Early Detection of Cancer - methods | Follow-Up Studies | Humans | Middle Aged | Neoplasm Invasiveness - prevention & control | Papillomavirus Infections - epidemiology | Uterine Cervical Neoplasms - epidemiology | Uterine Cervical Neoplasms - prevention & control | Europe - epidemiology | Incidence | Randomized Controlled Trials as Topic | Young Adult | Multicenter Studies as Topic | Papillomavirus Infections - prevention & control | Cytological Techniques | Cervical Intraepithelial Neoplasia - prevention & control | Adult | Female | Cervical Intraepithelial Neoplasia - epidemiology | Precancerous Conditions - prevention & control | Colposcopy - standards | Prevention | Diagnosis | Papillomavirus infections | Cervical cancer | Studies | Human papillomavirus | Medical screening | Index Medicus | Abridged Index Medicus
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2. Full Text Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
by Kang, Tae-Won and Yevsa, Tetyana and Woller, Norman and Hoenicke, Lisa and Wuestefeld, Torsten and Dauch, Daniel and Hohmeyer, Anja and Gereke, Marcus and Rudalska, Ramona and Potapova, Anna and Iken, Marcus and Vucur, Mihael and Weiss, Siegfried and Heikenwalder, Mathias and Khan, Sadaf and Gil, Jesus and Bruder, Dunja and Manns, Michael and Schirmacher, Peter and Tacke, Frank and Ott, Michael and Luedde, Tom and Longerich, Thomas and Kubicka, Stefan and Zender, Lars
Nature, ISSN 0028-0836, 11/2011, Volume 479, Issue 7374, pp. 547 - 551
Upon the aberrant activation of oncogenes, normal cells can enter the cellular senescence program, a state of stable cell-cycle arrest, which represents an... 
MODELS | RAS | PATHWAY | MULTIDISCIPLINARY SCIENCES | MOUSE | MICE | SUPPRESSION | EXPRESSION | FIBROBLASTS | P53 | Carcinoma, Hepatocellular - prevention & control | Humans | Hepatocytes - pathology | Hepatocytes - metabolism | CD4-Positive T-Lymphocytes - immunology | Cellular Senescence - immunology | Hepatocytes - cytology | Liver - immunology | Carcinoma, Hepatocellular - genetics | Liver Neoplasms - pathology | Precancerous Conditions - pathology | Carcinoma, Hepatocellular - immunology | Genes, ras - genetics | Liver Neoplasms - prevention & control | Cellular Senescence - genetics | Liver Neoplasms - genetics | Antigens, Neoplasm - immunology | Liver Neoplasms - immunology | Hepatocytes - immunology | Mice, SCID | Immunologic Surveillance - immunology | Precancerous Conditions - genetics | Disease Progression | Cancer Vaccines - immunology | Animals | Precancerous Conditions - immunology | Carcinoma, Hepatocellular - pathology | Liver - cytology | Mice | Precancerous Conditions - prevention & control | Phagocytosis | Aging | Liver cancer | Research | Liver cells | Health aspects | Abnormalities | Lymphocytes | Cancer | Immune system | Index Medicus
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3. Full Text Cross-protective efficacy of HPV-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by non-vaccine oncogenic HPV types: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial
by Wheeler, Cosette M, Dr, Prof and Castellsagué, Xavier, PhD and Garland, Suzanne M, Prof and Szarewski, Anne, PhD and Paavonen, Jorma, Prof and Naud, Paulo, Prof and Salmerón, Jorge, Prof and Chow, Song-Nan, Prof and Apter, Dan, MD and Kitchener, Henry, Prof and Teixeira, Júlio C, MD and Skinner, S Rachel, PhD and Jaisamrarn, Unnop, Prof and Limson, Genara, Prof and Romanowski, Barbara, Prof and Aoki, Fred Y, Prof and Schwarz, Tino F, Prof and Poppe, Willy A J, Prof and Bosch, F Xavier, PhD and Harper, Diane M, MD and Huh, Warner, MD and Hardt, Karin, PhD and Zahaf, Toufik, PhD and Descamps, Dominique, MD and Struyf, Frank, MD and Dubin, Gary, MD and Lehtinen, Matti, Prof and HPV PATRICIA Study Grp and HPV PATRICIA Study Group
Lancet Oncology, The, ISSN 1470-2045, 2012, Volume 13, Issue 1, pp. 100 - 110
Summary Background We evaluated the efficacy of the human papillomavirus HPV-16/18 AS04-adjuvanted vaccine against non-vaccine oncogenic HPV types in the... 
Hematology, Oncology and Palliative Medicine | UNITED-STATES | AGED 16-26 YEARS | ONCOLOGY | PARTICLE VACCINE | NEOPLASIA | MAJOR CAPSID PROTEIN | YOUNG-WOMEN | CANCER | HUMAN-PAPILLOMAVIRUS INFECTION | LESIONS | EPITOPES | South America | Cervical Intraepithelial Neoplasia - pathology | Human papillomavirus 18 - immunology | Adjuvants, Immunologic - administration & dosage | Humans | Lipid A - analogs & derivatives | DNA, Viral - analysis | Uterine Cervical Neoplasms - pathology | Aluminum Hydroxide - administration & dosage | Human papillomavirus 16 - immunology | North America | Papillomavirus Infections - diagnosis | Young Adult | Neoplasm Grading | Precancerous Conditions - diagnosis | Precancerous Conditions - virology | Time Factors | Adult | Female | Papillomavirus Infections - virology | Precancerous Conditions - pathology | Human papillomavirus 18 - genetics | Papillomavirus Vaccines - administration & dosage | Lipid A - administration & dosage | Uterine Cervical Neoplasms - diagnosis | Double-Blind Method | Europe | Uterine Cervical Neoplasms - prevention & control | Cervical Intraepithelial Neoplasia - diagnosis | Treatment Outcome | Cervical Intraepithelial Neoplasia - virology | Cross Reactions | Antigens, Viral - immunology | Asia | Papillomavirus Infections - prevention & control | Adolescent | Cervical Intraepithelial Neoplasia - prevention & control | Uterine Cervical Neoplasms - virology | Precancerous Conditions - prevention & control | Australia | Human papillomavirus 16 - genetics | Prevention | Medical colleges | Analysis | Oncology, Experimental | Clinical trials | Cross infection | Vaccines | Nosocomial infections | Research | Papillomavirus infections | Cancer | Index Medicus
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4. Full Text The benefit of mass eradication of Helicobacter pylori infection: a community-based study of gastric cancer prevention
by Lee, Yi-Chia and Chen, Tony Hsiu-Hsi and Chiu, Han-Mo and Shun, Chia-Tung and Chiang, Hung and Liu, Tzeng-Ying and Wu, Ming-Shiang and Lin, Jaw-Town
Gut, ISSN 0017-5749, 05/2013, Volume 62, Issue 5, pp. 676 - 682
Objective To evaluate the benefit of mass eradication of Helicobacter pylori infection in reducing premalignant gastric lesions. Design Mass eradication of H... 
COST-EFFECTIVENESS ANALYSIS | DESIGN | TAIWAN | ENDOSCOPIC RESECTION | MARKOV MODEL | RISK | CLASSIFICATION | THERAPIES | RANDOMIZED CONTROLLED-TRIAL | GASTROENTEROLOGY & HEPATOLOGY | CARCINOMA | Metaplasia - microbiology | Recurrence | Prevalence | Follow-Up Studies | Humans | Middle Aged | Peptic Ulcer - prevention & control | Helicobacter pylori - drug effects | Male | Multiphasic Screening | Incidence | Anti-Bacterial Agents - therapeutic use | Peptic Ulcer - microbiology | Helicobacter Infections - drug therapy | Adult | Female | Helicobacter Infections - diagnosis | Drug Therapy, Combination | Odds Ratio | Anti-Ulcer Agents - therapeutic use | Risk Factors | Breath Tests | Helicobacter Infections - epidemiology | Treatment Outcome | Clarithromycin - therapeutic use | Stomach Neoplasms - microbiology | Algorithms | Stomach Neoplasms - prevention & control | Taiwan - epidemiology | Metaplasia - prevention & control | Precancerous Conditions - microbiology | Precancerous Conditions - prevention & control | Prevention | Helicobacter infections | Research | Stomach cancer | Disease prevention | Studies | Surveillance | Disease | Ulcers | Mortality | Sanitation | Infections | Endoscopy | Index Medicus | Abridged Index Medicus | molecular oncology | colonic neoplasms | colorectal adenomas | cancer prevention | gastric lymphoma | helicobacter pylori - pathogenesis | cancer registries | oesophageal cancer | colonic polyps | chemoprevention | Helicobacter Pylori | colorectal cancer screening | endoscopic polypectomy | colonoscopy | colorectal neoplasia | gastric cancer | meta-analysis | endoscopy | gastro-oesophageal reflux disease | endoscopic procedures | colorectal neoplasm | cancer epidemiology | 1506 | gastrointestinal neoplasia | statistics
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5. Full Text Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final analysis of a double-blind, randomised study in young women
by Paavonen, J, Prof and Naud, P, Prof and Salmerón, J, Prof and Wheeler, CM, Prof and Chow, S-N, Prof and Apter, D, MD and Kitchener, H, Prof and Castellsague, X, MD and Teixeira, JC, MD and Skinner, SR, PhD and Hedrick, J, MD and Jaisamrarn, U, MD and Limson, G, Prof and Garland, S, Prof and Szarewski, A, PhD and Romanowski, B, Prof and Aoki, FY, Prof and Schwarz, TF, Prof and Poppe, WAJ, Prof and Bosch, FX, MD and Jenkins, D, Prof and Hardt, K, PhD and Zahaf, T, PhD and Descamps, D, MD and Struyf, F, MD and Lehtinen, M, Prof and Dubin, G, MD and HPV PATRICIA Study Grp and HPV PATRICIA Study Group
Lancet, The, ISSN 0140-6736, 2009, Volume 374, Issue 9686, pp. 301 - 314
Summary Background The human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine was immunogenic, generally well tolerated, and effective against HPV-16 or... 
Internal Medicine | UNITED-STATES | AGED 16-26 YEARS | CONTROLLED-TRIAL | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | PARTICLE VACCINE | NEOPLASIA | FOLLOW-UP | CANCER PREVENTION | CROSS-PROTECTION | LESIONS | Mass Vaccination | Papillomavirus Infections - complications | Sexual Behavior | Double-Blind Method | Humans | Uterine Cervical Neoplasms - prevention & control | Treatment Outcome | Vaginal Smears | Cervical Intraepithelial Neoplasia - virology | Human papillomavirus 18 | Young Adult | Human papillomavirus 16 | Precancerous Conditions - virology | Adolescent | Cervical Intraepithelial Neoplasia - prevention & control | Uterine Cervical Neoplasms - virology | Adult | Female | Papillomavirus Infections - virology | Papillomavirus Vaccines - immunology | Precancerous Conditions - prevention & control | Safety | Neoplasm Staging | Prevention | Papillomavirus infections | Research | Human papillomavirus | Immunization | Biomedical research | Womens health | Autoimmune diseases | Cervical cancer | Public health | Index Medicus | Abridged Index Medicus
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6. Full Text Efficacy of a bivalent HPV 16/18 vaccine against anal HPV 16/18 infection among young women: a nested analysis within the Costa Rica Vaccine Trial
by Kreimer, Aimée R, Dr and González, Paula, MD and Katki, Hormuzd A, PhD and Porras, Carolina, MS and Schiffman, Mark, MD and Rodriguez, Ana Cecilia, MD and Solomon, Diane, MD and Jiménez, Silvia, MS and Schiller, John T, PhD and Lowy, Douglas R, MD and van Doorn, Leen-Jan, PhD and Struijk, Linda, PhD and Quint, Wim, PhD and Chen, Sabrina, BS and Wacholder, Sholom, PhD and Hildesheim, Allan, PhD and Herrero, Rolando, MD and CVT Vaccine Grp and CVT Vaccine Group
Lancet Oncology, The, ISSN 1470-2045, 2011, Volume 12, Issue 9, pp. 862 - 870
Summary Background Anal cancer remains rare (incidence of about 1·5 per 100 000 women yearly), but rates are increasing in many countries. Human papillomavirus... 
Hematology, Oncology and Palliative Medicine | BROAD-SPECTRUM | QUADRIVALENT VACCINE | ASSAY | ONCOLOGY | PARTICLE VACCINE | PREVENTION | HUMAN-PAPILLOMAVIRUS | CANCER | CARCINOMA | PCR | EPIDEMIOLOGY | Human papillomavirus 18 - immunology | Precancerous Conditions - epidemiology | Adjuvants, Immunologic - administration & dosage | Prevalence | Humans | Lipid A - analogs & derivatives | Uterine Cervical Neoplasms - epidemiology | Anus Neoplasms - prevention & control | Anus Neoplasms - virology | Aluminum Hydroxide - administration & dosage | Human papillomavirus 16 - immunology | Young Adult | Precancerous Conditions - virology | Time Factors | Adult | Female | Immunization Schedule | Papillomavirus Infections - virology | Anus Neoplasms - epidemiology | Papillomavirus Vaccines - administration & dosage | Lipid A - administration & dosage | Double-Blind Method | Risk Assessment | Papillomavirus Infections - epidemiology | Risk Factors | Uterine Cervical Neoplasms - prevention & control | Treatment Outcome | Chi-Square Distribution | Papillomavirus Infections - prevention & control | Adolescent | Costa Rica - epidemiology | Uterine Cervical Neoplasms - virology | Precancerous Conditions - prevention & control | Clinical trials | Research | Vaccines | Papillomavirus infections | Oncology, Experimental | Cancer | Index Medicus
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7. Full Text Traditional Chinese medicine (Xiaoai Jiedu Decoction) as an adjuvant treatment for prevention new colorectal adenomatous polyp occurrence in post-polypectomy: Study protocol for a randomized controlled trial
by Zhou, Qing and Chen, Yu-Gen and Xiao, Jun and Chen, Ting-Ting and Liu, Jian-Rong and Zhou, Wan and Li, Wei-Zhong and Wang, Yan and Zhang, Bei-Ping and Lin, Jiang and Meng, Fan-Dong and Gong, Biao and Zheng, Guo-Ying and Han, Shu-Tang and Cheng, Hai-Bo
Medicine, ISSN 0025-7974, 08/2019, Volume 98, Issue 31, pp. e16680 - e16680
Colorectal Adenomatous Polyp (CAP) was one precursor of colorectal cancer (CRC) and having a high chance of developing into CRC. There was a lack of conclusive... 
Adenomatous Polyps - prevention & control | Multicenter Studies as Topic | Double-Blind Method | Medicine, Chinese Traditional | Humans | Colorectal Neoplasms - prevention & control | Precancerous Conditions - prevention & control | Drugs, Chinese Herbal - therapeutic use | Randomized Controlled Trials as Topic | COLONOSCOPY | MEDICINE, GENERAL & INTERNAL | SURVEILLANCE | Chinese herbal medicine | RISK | Xiaoai Jiedu decoction | colorectal adenomatous polyp | CANCER | randomized controlled trial | Prevention | Care and treatment | Usage | Relapse | Rectal polyps | Medicine, Chinese | Postoperative care | Methods | Diseases | Index Medicus | Abridged Index Medicus
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8. Full Text Fifteen-year effects of helicobacter pylori, garlic, and vitamin treatments on gastric cancer incidence and mortality
by Ma, Jun-Ling and Zhang, Lian and Brown, Linda M and Li, Ji-You and Shen, Lin and Pan, Kai-Feng and Liu, Wei-Dong and Hu, Yuanreng and Han, Zhong-Xiang and Crystal-Mansour, Susan and Pee, David and Blot, William J and Fraumeni, Joseph F and You, Wei-Cheng and Gail, Mitchell H
Journal of the National Cancer Institute, ISSN 0027-8874, 03/2012, Volume 104, Issue 6, pp. 488 - 492
In the Shandong Intervention Trial, 2 weeks of antibiotic treatment for Helicobacter pylori reduced the prevalence of precancerous gastric lesions, whereas 7.3... 
SUPPLEMENTATION | LINXIAN | GENERAL-POPULATION | FACTORIAL TRIAL | ONCOLOGY | CHINA | RISK | LESIONS | REDUCE | Precancerous Conditions - epidemiology | Follow-Up Studies | Humans | Middle Aged | Helicobacter pylori - drug effects | Male | Vitamins - pharmacology | Incidence | Anti-Bacterial Agents - therapeutic use | Helicobacter Infections - drug therapy | Adult | Female | Stomach Neoplasms - epidemiology | Odds Ratio | Omeprazole - therapeutic use | Helicobacter Infections - epidemiology | Proportional Hazards Models | Logistic Models | Factor Analysis, Statistical | China - epidemiology | Stomach Neoplasms - microbiology | Confounding Factors (Epidemiology) | Stomach Neoplasms - prevention & control | Amoxicillin - therapeutic use | Ascorbic Acid - pharmacology | Gastrointestinal Agents - therapeutic use | Aged | Garlic | Precancerous Conditions - microbiology | Precancerous Conditions - prevention & control | Dietary Supplements | Stomach Neoplasms - mortality | Vitamins - administration & dosage | Vitamin E - pharmacology | Care and treatment | Usage | Patient outcomes | Distribution | Helicobacter infections | Research | Stomach cancer | Health aspects | Vitamins | Clinical trials | Antibiotics | Mortality | Medical treatment | Gastroenterology | Cancer | Index Medicus | Brief Communication
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9. Full Text Meta-analysis: Can Helicobacter pylori eradication treatment reduce the risk for gastric cancer?
by Fuccio, Lorenzo and Zagari, Rocco Maurizio and Eusebi, Leonardo Henry and Laterza, Liboria and Cennamo, Vincenzo and Ceroni, Liza and Grilli, Diego and Bazzoli, Franco
Annals of Internal Medicine, ISSN 0003-4819, 07/2009, Volume 151, Issue 2, pp. 121 - 128
Background: Helicobacter pylori infection is associated with gastric cancer, but the effect of eradication treatment on gastric cancer risk is not well... 
MEDICINE, GENERAL & INTERNAL | INTESTINAL METAPLASIA | SYDNEY SYSTEM | CLINICAL-TRIALS | DOUBLE-BLIND | PREVENTION | FOLLOW-UP | INFECTION | RANDOMIZED CONTROLLED-TRIAL | PATHOLOGICAL-CHANGES | STOMACH-CANCER | Stomach - pathology | Humans | Middle Aged | Risk Factors | Male | Stomach Neoplasms - pathology | Treatment Outcome | Helicobacter Infections - pathology | Anti-Bacterial Agents - therapeutic use | Helicobacter pylori | Helicobacter Infections - drug therapy | Stomach Neoplasms - prevention & control | Adult | Female | Precancerous Conditions - pathology | Research Design - standards | Aged | Precancerous Conditions - prevention & control | Prevention | Complications and side effects | Care and treatment | Helicobacter infections | Research | Stomach cancer | Risk factors | Stomach | Bacteria | Medical treatment | Clinical outcomes | Meta-analysis | Cancer | Index Medicus | Abridged Index Medicus
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