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Journal Article
Pediatric Blood & Cancer, ISSN 1545-5009, 01/2015, Volume 62, Issue 1, pp. 91 - 98
Journal Article
2008, 1st ed., ISBN 0470248467, xiii, 1059
This book provides drug safety and toxicology scientists with practical guidance for testing and determining the effectiveness and safety of a new drug... 
Drugs -- Toxicology | Drugs -- Toxicity testing | MEDICAL / Pharmacology | Drugs--Toxicity testing | Drugs--Toxicology | Pharmacokinetics | Drug development | Drugs--Testing | Drugs | Toxicology | Handbooks, manuals, etc | Toxicity testing
Book
Pediatric Blood & Cancer, ISSN 1545-5009, 12/2007, Volume 49, Issue 7, pp. 928 - 940
Journal Article
Pediatric Blood and Cancer, ISSN 1545-5009, 07/2010, Volume 55, Issue 1, pp. 26 - 34
Background. MLN8237 is a small molecule inhibitor of Aurora Kinase A (AURKA) that is currently in early phase clinical testing. AURKA plays a pivotal role in... 
MLN8237 | Preclinical testing | Developmental therapeutics | XENOGRAFT MODELS | CELLS | PROTEIN | preclinical testing | developmental therapeutics | DRUG TARGETS | CANCER MODELS | GENE | ONCOLOGY | IN-VIVO | N-MYC | PEDIATRICS | CHECKPOINT | AGENTS | HEMATOLOGY | Humans | Neoplasms, Experimental - enzymology | Antineoplastic Agents - administration & dosage | Pyrimidines - chemistry | Aurora Kinase A | Dose-Response Relationship, Drug | Neoplasms, Experimental - pathology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Protein Kinase Inhibitors - chemistry | Azepines - chemistry | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Female | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Administration, Oral | Pyrimidines - administration & dosage | Kaplan-Meier Estimate | Aurora Kinases | Pyrimidines - pharmacology | Antineoplastic Agents - chemistry | Mice, SCID | Azepines - pharmacology | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors - administration & dosage | Animals | Mice, Nude | Precursor Cell Lymphoblastic Leukemia-Lymphoma - enzymology | Mice, Inbred NOD | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | Azepines - administration & dosage | Neoplasms, Experimental - drug therapy | Index Medicus | Preclinical Testing | Developmental Therapeutics
Journal Article
Pediatric Blood & Cancer, ISSN 1545-5009, 02/2014, Volume 61, Issue 2, pp. 380 - 382
Journal Article