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1. Full Text T-Lymphoblastic Leukemia/Lymphoma
by You, M. James and Medeiros, L. Jeffrey and Hsi, Eric D
American Journal of Clinical Pathology, ISSN 0002-9173, 09/2015, Volume 144, Issue 3, pp. 411 - 422
Objectives To review important concepts from the 2013 Society for Hematopathology/European Association for Haematopathology Workshop session on T-acute... 
Genetics | Immunophenotype | Early T-cell precursor | T-ALL | MALIGNANCY | NOTCH1 | PEDIATRIC LEUKEMIA | LYMPHOMA | THYMOMA | MUTATIONS | PATHOLOGY | EXPRESSION | Lymphoma, T-Cell - immunology | Animals | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - diagnosis | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Humans | Cytogenetic Analysis - methods | Pathology, Molecular - methods | Immunophenotyping | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - immunology | Lymphoma, T-Cell - genetics | Translocation, Genetic - genetics
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2. Full Text Early T-cell precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) in adolescents and adults: A high-risk subtype
by Jain, Nitin and Lamb, Audrey V and O'Brien, Susan and Ravandi, Farhad and Konopleva, Marina and Jabbour, Elias and Zuo, Zhuang and Jorgensen, Jeffrey and Lin, Pei and Pierce, Sherry and Thomas, Deborah and Rytting, Michael and Borthakur, Gautam and Kadia, Tapan and Cortes, Jorge and Kantarjian, Hagop M and Khoury, Joseph D
Blood, ISSN 0006-4971, 04/2016, Volume 127, Issue 15, pp. 1863 - 1869
Early T-cell precursor (ETP) acute lymphoblastic leukemia/lymphoma (ALL/LBL) is a recently recognized high-risk T lymphoblastic leukemia/lymphoma (T-ALL/LBL)... 
Recurrence | Prognosis | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Proportional Hazards Models | Immunophenotyping | Male | Treatment Outcome | Remission Induction | Young Adult | Disease-Free Survival | CD3 Complex - genetics | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - diagnosis | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Adolescent | Adult | Female | Aged | Cell Differentiation | Antigens, CD1 - genetics | Precursor Cells, T-Lymphoid - immunology | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - therapy | 100 | Clinical Trials and Observations
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3. Full Text Childhood acute lymphoblastic leukemia: Progress through collaboration
by Pui, Ching-Hon and Yang, Jun J and Hunger, Stephen P and Pieters, Rob and Schrappe, Martin and Biondi, Andrea and Vora, Ajay and Baruchel, André and Silverman, Lewis B and Schmiegelow, Kjeld and Escherich, Gabriele and Horibe, Keizo and Benoit, Yves C.M and Izraeli, Shai and Yeoh, Allen Eng Juh and Liang, Der-Cherng and Downing, James R and Evans, William E and Relling, Mary V and Mullighan, Charles G
Journal of Clinical Oncology, ISSN 0732-183X, 09/2015, Volume 33, Issue 27, pp. 2938 - 2948
Purpose To review the impact of collaborative studies on advances in the biology and treatment of acute lymphoblastic leukemia (ALL) in children and... 
KINASE INHIBITOR THERAPY | ASPARAGINASE ANTIBODIES | ONCOLOGY | B-CELL PRECURSOR | DOWN-SYNDROME | TREATMENT RESPONSE | GENOME-WIDE | BFM STUDY-GROUP | T-CELL | MINIMAL RESIDUAL DISEASE | CHILDRENS ONCOLOGY GROUP | Predictive Value of Tests | Genetic Testing | History, 21st Century | Humans | Child, Preschool | Infant | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy | Time Factors | Child | Infant, Newborn | Precision Medicine | Pediatrics - trends | Genetic Predisposition to Disease | History, 20th Century | Survivors | Cooperative Behavior | Treatment Outcome | International Cooperation | Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Interdisciplinary Communication | Phenotype | Medical Oncology - trends | Adolescent | Age of Onset | Diffusion of Innovation | Biomarkers, Tumor - genetics | Index Medicus | Pedi2 | Review
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4. Full Text Minimal residual disease diagnostics in acute lymphoblastic leukemia: Need for sensitive, fast, and standardized technologies
by Dongen, Jacques and Velden, Vincent and Brüggemann, Monika and Orfao, Alberto
Blood, ISSN 0006-4971, 06/2015, Volume 125, Issue 26, pp. 3996 - 4009
textabstractMonitoring of minimal residual disease (MRD) has become routine clinical practice in frontline treatment of virtually all childhood acute... 
MRD-STUDY-GROUP | POLYMERASE-CHAIN-REACTION | RECEPTOR GENE REARRANGEMENTS | CHILDHOOD T-CELL | TIME QUANTITATIVE PCR | RANDOMIZED CONTROLLED-TRIAL | FLOW-CYTOMETRY | STEM-CELL TRANSPLANTATION | HEMATOLOGY | CHILDRENS ONCOLOGY GROUP | PRECURSOR-B-ALL | Flow Cytometry - methods | Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis | High-Throughput Nucleotide Sequencing - methods | Humans | Neoplasm, Residual - diagnosis | Review Series | Acute Lymphoblastic Leukemia
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5. Full Text Phase I/Phase II study of blinatumomab in pediatric patients with relapsed/refractory acute lymphoblastic leukemia
by Von Stackelberg, Arend and Locatelli, Franco and Zugmaier, Gerhard and Handgretinger, Rupert and Trippett, Tanya M and Rizzari, Carmelo and Bader, Peter and O'brien, Maureen M and Brethon, Benôit and Bhojwani, Deepa and Schlegel, Paul Gerhardt and Borkhardt, Arndt and Rheingold, Susan R and Cooper, Todd Michael and Zwaan, Christian M and Barnette, Phillip and Messina, Chiara and Michel, Ǵerard and Dubois, Steven G and Hu, Kuolung and Zhu, Min and Whitlock, James A and Gore, Lia
Journal of Clinical Oncology, ISSN 0732-183X, 12/2016, Volume 34, Issue 36, pp. 4381 - 4389
Purpose Blinatumomab is a bispecific T-cell engager antibody construct targeting CD19 on B-cell lympho-blasts. We evaluated the safety, pharmacokinetics,... 
RELAPSE | ACTIVATION | THERAPY | ONCOLOGY | CD19 | TERM-FOLLOW-UP | ANTIBODY | MINIMAL RESIDUAL DISEASE | T-CELLS | REMISSION | CHILDREN | Single-Blind Method | Drug Administration Schedule | Follow-Up Studies | Humans | Child, Preschool | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | Treatment Outcome | Antineoplastic Agents - therapeutic use | Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis | Dose-Response Relationship, Drug | Antibodies, Bispecific - therapeutic use | Disease-Free Survival | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Maximum Tolerated Dose | Antineoplastic Agents - adverse effects | Adolescent | Survival Analysis | Infusions, Intravenous | Child
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6. Full Text High Frequency and Poor Outcome of Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia in Adults
by Roberts, Kathryn G and Gu, Zhaohui and Payne-Turner, Debbie and McCastlain, Kelly and Harvey, Richard C and Chen, I-Ming and Pei, Deqing and Iacobucci, Ilaria and Valentine, Marcus and Pounds, Stanley B and Shi, Lei and Li, Yongjin and Zhang, Jinghui and Cheng, Cheng and Rambaldi, Alessandro and Tosi, Manuela and Spinelli, Orietta and Radich, Jerald P and Minden, Mark D and Rowe, Jacob M and Luger, Selina and Litzow, Mark R and Tallman, Martin S and Wiernik, Peter H and Bhatia, Ravi and Aldoss, Ibrahim and Kohlschmidt, Jessica and Mrózek, Krzysztof and Marcucci, Guido and Bloomfield, Clara D and Stock, Wendy and Kornblau, Stephen and Kantarjian, Hagop M and Konopleva, Marina and Paietta, Elisabeth and Willman, Cheryl L and Mullighan, Charles G
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, ISSN 0732-183X, 02/2017, Volume 35, Issue 4, pp. 394 - 401
Purpose Philadelphia chromosome (Ph) -like acute lymphoblastic leukemia (ALL) is a high-risk subtype of childhood ALL characterized by kinase-activating... 
KINASE INHIBITOR THERAPY | PH-LIKE | HYPER-CVAD | FUSION | ONCOLOGY | TYROSINE KINASE | ACUTE LYMPHOCYTIC-LEUKEMIA | REGIMEN | CLASSIFICATION | DASATINIB | MURINE XENOGRAFT MODELS | Prognosis | Age Factors | Humans | Middle Aged | Kaplan-Meier Estimate | Male | Treatment Outcome | Gene Expression Profiling | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - therapy | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Young Adult | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - diagnosis | Aged, 80 and over | Adult | Female | Aged | Translational Oncology | ORIGINAL REPORTS
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7. Full Text Improved Survival for Children and Adolescents With Acute Lymphoblastic Leukemia Between 1990 and 2005: A Report From the Children's Oncology Group
by Stephen P. Hunger and Xiaomin Lu and Meenakshi Devidas and Bruce M. Camitta and Paul S. Gaynon and Naomi J. Winick and Gregory H. Reaman and William L. Carroll
Journal of Clinical Oncology, ISSN 0732-183X, 05/2012, Volume 30, Issue 14, pp. 1663 - 1669
Purpose To examine population-based improvements in survival and the impact of clinical covariates on outcome among children and adolescents with acute... 
YOUNG-ADULTS | CANCER CLINICAL-TRIALS | PROGNOSTIC-FACTORS | GENE | ONCOLOGY | INFANTS | STEM-CELL TRANSPLANTATION | MINIMAL RESIDUAL DISEASE | EXPRESSION | B-PROGENITOR | RISK CLASSIFICATION | Multivariate Analysis | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Prognosis | Age Factors | United States | Humans | Child, Preschool | National Cancer Institute (U.S.) | Male | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | Cause of Death | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Time Factors | Female | Retrospective Studies | Child | Severity of Illness Index | Risk Assessment | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | Clinical Trials as Topic | Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis | Disease Progression | Disease-Free Survival | Adolescent | Sex Factors | Survival Analysis | Cohort Studies | Index Medicus | ORIGINAL REPORTS | Bone4 | Bone1
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8. Full Text Standardized flow cytometry for highly sensitive MRD measurements in B-cell acute lymphoblastic leukemia
by Theunissen, Prisca and Mejstrikova, Ester and Sedek, Lukasz and Van Der Sluijs-Gelling, Alita J and Gaipa, Giuseppe and Bartels, Marius and Sobral da Costa, Elaine and Kotrová, Michaela and Novakova, Michaela and Sonneveld, Edwin and Buracchi, Chiara and Bonaccorso, Paola and Oliveira, Elen and Te Marvelde, Jeroen G and Szczepanski, Tomasz and Lhermitte, Ludovic and Hrusak, Ondrej and Lecrevisse, Quentin and Grigore, Georgiana Emilia and Froňková, Eva and Trka, Jan and Brüggemann, Monika and Orfao, Alberto and Van Dongen, Jacques J. M and Van Der Velden, Vincent H. J and EuroFlow Consortium
Blood, ISSN 0006-4971, 01/2017, Volume 129, Issue 3, pp. 347 - 357
A fully-standardized EuroFlow 8-color antibody panel and laboratory procedure was stepwise designed to measure minimal residual disease (MRD) in B-cell... 
IG/TCR GENE REARRANGEMENTS | BONE-MARROW | IMMUNOGLOBULIN | TARGETS | MONOCLONAL-ANTIBODY | TIME QUANTITATIVE PCR | PROGNOSTIC-SIGNIFICANCE | HEMATOLOGY | MINIMAL RESIDUAL DISEASE | CHILDHOOD | EXPRESSION | Flow Cytometry - methods | Humans | Middle Aged | Child, Preschool | Infant | Male | Young Adult | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - diagnosis | Flow Cytometry - standards | Gene Rearrangement | Neoplasm, Residual - diagnosis | Sensitivity and Specificity | Adolescent | Adult | Female | Receptors, Antigen, B-Cell - genetics | Aged | Child | Real-Time Polymerase Chain Reaction | Infant, Newborn | Lymphoid Neoplasia
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9. Full Text Oncogenetics and minimal residual disease are independent outcome predictors in adult patients with acute lymphoblastic leukemia
by Beldjord, Kheira and Chevret, Sylvie and Asnafi, Vahid and Huguet, Françoise and Boulland, Marie-Laure and Leguay, Thibaut and Thomas, Xavier and Cayuela, Jean-Michel and Grardel, Nathalie and Chalandon, Yves and Boissel, Nicolas and Schaefer, Beat and Delabesse, Eric and Cavé, Hélène and Chevallier, Patrice and Buzyn, Agnes̀ and Fest, Thierry and Reman, Oumedaly and Vernant, Jean-Paul and Lhéritier, Veŕonique and Béńe, Marie C and Lafage, Marina and Macintyre, Elizabeth and Ifrah, Norbert and Dombret, Hervé and GRAALL and Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL)
Blood, ISSN 0006-4971, 06/2014, Volume 123, Issue 24, pp. 3739 - 3749
With intensified pediatric-like therapy and genetic disease dissection, the field of adult acute lymphoblastic leukemia (ALL) has evolved recently. In this new... 
YOUNG-ADULTS | NOTCH1/FBXW7 MUTATIONS | PROTOCOLS | B-CELL PRECURSOR | ADOLESCENTS | IKZF1 | HEMATOLOGY | EXPRESSION | DELETIONS | STANDARD | RISK CLASSIFICATION | Recurrence | Prognosis | Humans | Middle Aged | Male | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis | Neoplasm, Residual | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Young Adult | Multicenter Studies as Topic | DNA Mutational Analysis | Adolescent | Survival Analysis | Adult | Female | Biomarkers, Tumor - genetics | Retrospective Studies | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Index Medicus | Abridged Index Medicus
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10. Full Text Outcome of relapsed adult lymphoblastic leukemia depends on response to salvage chemotherapy, prognostic factors, and performance of stem cell transplantation
by Gökbuget, Nicola and Stanze, Daniel and Beck, Joachim and Diedrich, Helmut and Horst, Heinz-August and Hüttmann, Andreas and Kobbe, Guido and Kreuzer, Karl-Anton and Leimer, Lothar and Reichle, Albrecht and Schaich, Markus and Schwartz, Stefan and Serve, Hubert and Starck, Michael and Stelljes, Matthias and Stuhlmann, Reingard and Viardot, Andreas and Wendelin, Knut and Freund, Mathias and Hoelzer, Dieter and German Multictr Study Grp Adult and German Multicenter Study Group for Adult Acute Lymphoblastic Leukemia
Blood, ISSN 0006-4971, 09/2012, Volume 120, Issue 10, pp. 2032 - 2041
Despite improvements in first-line therapies, published results on the treatment of relapsed adult acute lymphoblastic leukemia (ALL) show that prognosis is... 
TRIALS | THERAPY | STANDARD-RISK | ACUTE LYMPHOCYTIC-LEUKEMIA | DISEASE | NELARABINE | PHASE-II | HEMATOLOGY | Recurrence | Age Factors | Biomarkers, Tumor - analysis | Humans | Middle Aged | Salvage Therapy | Male | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | Survival Rate | Treatment Outcome | Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis | Antineoplastic Agents - administration & dosage | Remission Induction | Stem Cell Transplantation | Fusion Proteins, bcr-abl - analysis | Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy | Adolescent | Adult | Female | Retrospective Studies
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