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Haematologica (Roma), ISSN 1592-8721, 2007, Volume 92, Issue 5, pp. 612 - 618
...{at}ospedaliriuniti.bergamo.it Background and Objectives: The molecular analysis of minimal residual disease (MRD) may provide informaton on the risk of recurrence in patients with acute lymphoblastic leukemia... 
ALL | Allogeneic transplantation | MRD | Adult ALL | adult ALL | BONE-MARROW-TRANSPLANTATION | IMMUNOGLOBULIN | TIME QUANTITATIVE PCR | REARRANGEMENTS | CHILDREN | IMATINIB | EXPANSION | Ph | TARGETS | MALIGNANCIES | allogeneic transplantation | FUSION GENE TRANSCRIPTS | HEMATOLOGY | Translocation, Genetic | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Humans | Middle Aged | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - surgery | Male | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Leukemia-Lymphoma, Adult T-Cell - drug therapy | Gene Deletion | Fusion Proteins, bcr-abl - blood | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - blood | Precursor Cell Lymphoblastic Leukemia-Lymphoma - blood | Basic Helix-Loop-Helix Transcription Factors - genetics | Hematopoietic Stem Cell Transplantation | Survival Rate | Combined Modality Therapy | Remission Induction | Adolescent | Survival Analysis | Oncogene Proteins, Fusion - blood | Kinetics | Transplantation Conditioning | Cohort Studies | Piperazines - administration & dosage | Clinical Trials as Topic - statistics & numerical data | Precursor Cell Lymphoblastic Leukemia-Lymphoma - surgery | Risk | Transplantation, Homologous | Neoplasm, Residual | Multicenter Studies as Topic | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - mortality | Polymerase Chain Reaction | Adult | Female | Myeloid-Lymphoid Leukemia Protein - blood | Gene Rearrangement, B-Lymphocyte | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | T-Cell Acute Lymphocytic Leukemia Protein 1 | Leukemia-Lymphoma, Adult T-Cell - genetics | Leukemia-Lymphoma, Adult T-Cell - surgery | Pyrimidines - administration & dosage | Gene Rearrangement, T-Lymphocyte | Leukemia-Lymphoma, Adult T-Cell - mortality | Kaplan-Meier Estimate | Proto-Oncogene Proteins - genetics | Treatment Outcome | Leukemia-Lymphoma, Adult T-Cell - pathology | Imatinib Mesylate | Biomarkers, Tumor - blood | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Leukemia-Lymphoma, Adult T-Cell - blood | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Benzamides
Journal Article
Journal of clinical oncology, ISSN 1527-7755, 2013, Volume 31, Issue 34, pp. 4333 - 4342
Purpose The Group for Research in Adult Acute Lymphoblastic Leukemia (GRAALL) recently reported a significantly better outcome in T-cell acute lymphoblastic leukemia... 
ACTIVATION | THERAPY | NOTCH1 | PRETHYMIC PHENOTYPE | ONCOLOGY | PATHWAY | GENES | PTEN | MUTATIONS | EXPRESSION | F-Box-WD Repeat-Containing Protein 7 | Multivariate Analysis | Predictive Value of Tests | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Humans | Male | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - mortality | Young Adult | Time Factors | DNA Mutational Analysis | Gene Deletion | Cell Cycle Proteins - genetics | Adult | Female | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - therapy | PTEN Phosphohydrolase - genetics | Genetic Predisposition to Disease | Membrane Proteins - genetics | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Proto-Oncogene Proteins - genetics | Disease-Free Survival | Phenotype | GTP Phosphohydrolases - genetics | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - classification | Mutation | Receptor, Notch1 - genetics | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | GTP Phosphohydrolases | ras Proteins | Innate immunity | Life Sciences | F-Box Proteins | Immunology | PTEN Phosphohydrolase | Proto-Oncogene Proteins | Membrane Proteins | Ubiquitin-Protein Ligases | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Receptor, Notch1 | Cell Cycle Proteins
Journal Article
Journal Article
Journal of clinical oncology, ISSN 1527-7755, 2015, Volume 33, Issue 27, pp. 2938 - 2948
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2014, Volume 371, Issue 11, pp. 1005 - 1015
BACKGROUND Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is characterized by a gene-expression profile similar to that of... 
MEDICINE, GENERAL & INTERNAL | MODELS | B-CELL PRECURSOR | INHIBITOR THERAPY | IMATINIB | PEDIATRIC ACUTE LEUKEMIAS | GENE FUSION | EXPRESSION | ETV6-NTRK3 FUSION TRANSCRIPTS | CRLF2 | DELETION | Oligonucleotide Array Sequence Analysis | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Humans | Child, Preschool | Infant | Male | Young Adult | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Heterografts | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - mortality | Adult | Female | DNA, Neoplasm - analysis | Receptors, Cytokine - metabolism | Child | Philadelphia Chromosome | Receptors, Cytokine - genetics | Signal Transduction - genetics | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Animals | Protein Kinase Inhibitors - therapeutic use | Adolescent | Survival Analysis | Mice | Polymorphism, Single Nucleotide | Genome, Human | Protein-Tyrosine Kinases - antagonists & inhibitors | Development and progression | Care and treatment | Genetic aspects | Research | Lymphocytic leukemia | Tyrosine metabolism | Cell proliferation | Tyk2 protein | Leukemia | Genes | Clinical trials | Oncology | Genomes | Kinases | Cell activation | Janus kinase 2 | Xenografts | Teenagers | Children | Adolescents | Protein-tyrosine kinase | Age | Tyrosine | Young adults | Genomic analysis | Acute lymphatic leukemia | Stat5 protein | Lymphatic leukemia | Gene expression | Philadelphia chromosome | Interleukin 7 receptors | Thymic stromal lymphopoietin | Lymphocytes B
Journal Article
Blood, ISSN 1528-0020, 2013, Volume 122, Issue 19, pp. 3298 - 3307
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2015, Volume 373, Issue 16, pp. 1541 - 1552
Journal Article
Cancer, ISSN 0008-543X, 2017, Volume 123, Issue 2, pp. 294 - 302
BACKGROUND Minimal residual disease (MRD) assessment predicts survival for patients with newly diagnosed acute lymphoblastic leukemia... 
relapsed | refractory | inotuzumab | blinatumomab | minimal residual disease | acute lymphoblastic leukemia | ADULT PATIENTS | PROGNOSIS | INOTUZUMAB OZOGAMICIN | ACUTE LYMPHOCYTIC-LEUKEMIA | INDUCTION | TRANSPLANTATION | ONCOLOGY | FLOW-CYTOMETRY | MRD | CLINICAL-SIGNIFICANCE | Neoplasm, Residual - pathology | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Humans | Middle Aged | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | Antineoplastic Agents - therapeutic use | Neoplasm Recurrence, Local - mortality | Neoplasm Recurrence, Local - pathology | Young Adult | Disease-Free Survival | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Stem Cell Transplantation - methods | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - mortality | Adolescent | Aged, 80 and over | Adult | Aged | B-Lymphocytes - pathology | Hematopoietic Stem Cell Transplantation - methods | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Salvage Therapy - methods | Flow cytometry | Cell survival | Acute lymphatic leukemia | Identification methods | Leukemia | Minimal residual disease | Stem cell transplantation | Transplantation | Lymphatic leukemia | Patients | Survival | Doxorubicin | Vincristine | Cytometry | Cyclophosphamide | Salvage | Lymphocytes B | Stem cells | Remission | Adults | Cancer | Acute lymphoblastic leukemia
Journal Article