X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (598) 598
humans (575) 575
mice (516) 516
precursor cells, b-lymphoid - metabolism (404) 404
immunology (243) 243
hematology (236) 236
precursor cells, b-lymphoid - cytology (207) 207
precursor cells, b-lymphoid - immunology (206) 206
female (203) 203
expression (192) 192
male (183) 183
oncology (172) 172
mice, inbred c57bl (168) 168
flow cytometry (165) 165
cell biology (160) 160
b-lymphocytes - metabolism (155) 155
cells, cultured (154) 154
differentiation (152) 152
leukemia (145) 145
cell differentiation (142) 142
gene expression (142) 142
signal transduction (126) 126
b cells (123) 123
apoptosis (122) 122
mice, knockout (122) 122
cell proliferation (119) 119
cell line (114) 114
acute lymphoblastic-leukemia (111) 111
biochemistry & molecular biology (109) 109
genetic aspects (109) 109
research (109) 109
bone-marrow (106) 106
b-lymphocytes - immunology (105) 105
precursor cells, b-lymphoid - pathology (105) 105
abridged index medicus (104) 104
hemic and lymphatic diseases (104) 104
mice, transgenic (104) 104
cancer (103) 103
bone marrow (102) 102
precursor cell lymphoblastic leukemia-lymphoma - genetics (101) 101
proteins (100) 100
adult (96) 96
lymphocytes (94) 94
child (92) 92
precursor cells, b-lymphoid - drug effects (92) 92
b-lymphocytes - cytology (91) 91
precursor cell lymphoblastic leukemia-lymphoma - metabolism (90) 90
activation (88) 88
multidisciplinary sciences (88) 88
precursor cell lymphoblastic leukemia-lymphoma - pathology (88) 88
cell line, tumor (82) 82
genes (81) 81
lymphocytes b (80) 80
analysis (79) 79
adolescent (77) 77
gene (77) 77
mutation (75) 75
research article (75) 75
stem cells (74) 74
middle aged (71) 71
receptor (71) 71
acute lymphocytic leukemia (70) 70
child, preschool (70) 70
health aspects (67) 67
transcription factors (66) 66
precursor cells, b-lymphoid - physiology (63) 63
cell differentiation - genetics (62) 62
medicine, research & experimental (61) 61
cell differentiation - immunology (60) 60
physiological aspects (60) 60
reverse transcriptase polymerase chain reaction (60) 60
rodents (60) 60
transcription (60) 60
bone marrow cells - metabolism (59) 59
immunophenotyping (59) 59
blotting, western (58) 58
hematopoietic stem cells - metabolism (57) 57
medicine (57) 57
kinases (56) 56
lymphopoiesis (56) 56
biology (55) 55
dna-binding proteins - genetics (55) 55
dna-binding proteins - metabolism (55) 55
precursor b-cell lymphoblastic leukemia-lymphoma - pathology (55) 55
proliferation (55) 55
gene-expression (53) 53
phosphorylation (53) 53
b-lymphocytes - pathology (52) 52
cell cycle (52) 52
hematopoietic stem-cells (52) 52
aged (51) 51
gene expression profiling (51) 51
hematopoietic stem cells - cytology (51) 51
immunoglobulins (51) 51
precursors (51) 51
vj recombination (51) 51
cell lineage (50) 50
gene expression regulation (49) 49
genetics & heredity (49) 49
identification (49) 49
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature (London), ISSN 1476-4687, 2017, Volume 542, Issue 7642, pp. 479 - 483
B-lymphoid transcription factors, such as PAX5 and IKZF1, are critical for early B-cell development(1,2... 
ENERGY STRESS | ACTIVATION | GENE | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | ACUTE LYMPHOBLASTIC-LEUKEMIA | HEMATOPOIETIC STEM-CELLS | REGULATORY NETWORK | DIFFERENTIATION | MINIMAL RESIDUAL DISEASE | EXPRESSION | Glucocorticoids - therapeutic use | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Receptor, Cannabinoid, CB2 - agonists | Humans | Gene Expression Regulation, Neoplastic | Receptors, Glucocorticoid - metabolism | PAX5 Transcription Factor - deficiency | Carrier Proteins - agonists | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Chromatin Immunoprecipitation | Adenosine Triphosphate - metabolism | Cell Death | Pyruvic Acid - metabolism | Female | Ikaros Transcription Factor - metabolism | Energy Metabolism - genetics | B-Lymphocytes - metabolism | PAX5 Transcription Factor - metabolism | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | AMP-Activated Protein Kinases - antagonists & inhibitors | Carcinogenesis - genetics | PAX5 Transcription Factor - genetics | Mice, Transgenic | Citric Acid Cycle | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Transcription Factors - metabolism | B-Lymphocytes - drug effects | Receptor, Cannabinoid, CB2 - metabolism | Animals | Carrier Proteins - metabolism | Sequence Analysis, RNA | Glucocorticoids - pharmacology | Glucose - metabolism | Mice | Physiological aspects | Transcription factors | B cells | Proteins | Metabolites | Rodents | Cloning | Leukemia | Glucose | Kinases | Metabolism | Gene expression | Apoptosis
Journal Article
Blood, ISSN 1528-0020, 2012, Volume 119, Issue 2, pp. 494 - 502
Journal Article
Genes and Development, ISSN 0890-9369, 11/2016, Volume 30, Issue 22, pp. 2486 - 2499
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2012, Volume 209, Issue 13, pp. 2467 - 2483
.... We report here that, in the adult mouse, Bcl11a is expressed in most hematopoietic cells and is highly enriched in B cells, early T cell progenitors, common lymphoid progenitors (CLPs... 
B-CELL DEVELOPMENT | RECEPTOR-DEFICIENT MICE | LINEAGE COMMITMENT | E2A PROTEINS | MEDICINE, RESEARCH & EXPERIMENTAL | GENE REARRANGEMENTS | MULTIPOTENT PROGENITORS | CRITICAL ROLES | HEMATOPOIETIC STEM-CELLS | TRANSCRIPTION | IMMUNOLOGY | MOUSE BONE-MARROW | Proto-Oncogene Proteins c-mdm2 - genetics | Apoptosis - drug effects | Precursor Cells, B-Lymphoid - metabolism | Lymphopoiesis - genetics | Precursor Cells, B-Lymphoid - immunology | Precursor Cells, B-Lymphoid - drug effects | Mice, 129 Strain | Adaptive Immunity - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Lymphopoiesis - physiology | Mice, Mutant Strains | Nuclear Proteins - deficiency | Precursor Cells, T-Lymphoid - metabolism | Precursor Cells, T-Lymphoid - cytology | Cell Differentiation | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-mdm2 - metabolism | Carrier Proteins - immunology | Adaptive Immunity - physiology | Down-Regulation | Mice, Inbred C57BL | Tumor Suppressor Protein p53 - metabolism | Mice, Transgenic | Nuclear Proteins - metabolism | Binding Sites - genetics | Gene Knockout Techniques | Nuclear Proteins - immunology | Carrier Proteins - genetics | Proto-Oncogene Proteins c-bcl-2 - pharmacology | Animals | Carrier Proteins - metabolism | Precursor Cells, B-Lymphoid - cytology | Mice | Precursor Cells, T-Lymphoid - immunology | Proto-Oncogene Proteins c-bcl-2 - genetics
Journal Article
Nature, ISSN 0028-0836, 05/2015, Volume 521, Issue 7552, pp. 357 - 361
B cells are selected for an intermediate level of B-cell antigen receptor (BCR) signalling strength... 
MOTIFS | RECEPTOR | ACTIVATION | MULTIDISCIPLINARY SCIENCES | IN-VIVO | DELETION | Protein-Tyrosine Kinases - metabolism | Receptors, Antigen, B-Cell - deficiency | Humans | Precursor Cells, B-Lymphoid - metabolism | Inositol Polyphosphate 5-Phosphatases | Intracellular Signaling Peptides and Proteins - metabolism | Precursor Cells, B-Lymphoid - drug effects | Receptors, Antigen, B-Cell - metabolism | Antigens, CD - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Precursor Cells, B-Lymphoid - pathology | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Gene Deletion | Female | B-Lymphocytes - pathology | Cell Death - drug effects | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Syk Kinase | B-Lymphocytes - metabolism | Disease Models, Animal | Phosphoric Monoester Hydrolases - antagonists & inhibitors | Enzyme Activation - drug effects | Mice, SCID | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Xenograft Model Antitumor Assays | B-Lymphocytes - drug effects | Fusion Proteins, bcr-abl - genetics | Tyrosine - metabolism | Animals | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Signal Transduction - drug effects | Cell Transformation, Neoplastic | Intracellular Signaling Peptides and Proteins - agonists | Cell Line, Tumor | Mice, Inbred NOD | Receptors, Antigen, B-Cell - genetics | Mice | Amino Acid Motifs - genetics | Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases | Phosphoric Monoester Hydrolases - metabolism | Receptors, Immunologic - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - deficiency | Receptors, Immunologic - metabolism | Drug Resistance, Neoplasm - drug effects | Physiological aspects | Acute lymphocytic leukemia | B cells | Signal transduction | Rodents | Leukemia | Mutation | Drug resistance | Kinases | Cells
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2010, Volume 11, Issue 7, pp. 635 - 643
Journal Article
Cancer cell, ISSN 1535-6108, 2013, Volume 24, Issue 3, pp. 289 - 304
... cells and plasma cells and that contributes to clinical PI resistance. Xbp1s− tumor B cells and pre-plasmablasts survive therapeutic PI, preventing cure... 
BORTEZOMIB RESISTANCE | OVEREXPRESSION | DEXAMETHASONE | BLIMP-1 | UNFOLDED PROTEIN RESPONSE | ONCOLOGY | FACTOR XBP-1 | MECHANISMS | DIFFERENTIATION | CANCER | GENOME | CELL BIOLOGY | eIF-2 Kinase - metabolism | Humans | Precursor Cells, B-Lymphoid - metabolism | Transcription Factors - deficiency | Pyrazines - therapeutic use | Boronic Acids - therapeutic use | DNA-Binding Proteins - deficiency | X-Box Binding Protein 1 | Plasma Cells - pathology | DNA-Binding Proteins - metabolism | Multiple Myeloma - drug therapy | Precursor Cells, B-Lymphoid - pathology | Plasma Cells - metabolism | Membrane Proteins - metabolism | Protein-Serine-Threonine Kinases - metabolism | Cell Survival - drug effects | Bortezomib | Endoribonucleases - metabolism | Proteasome Inhibitors - pharmacology | Signal Transduction | Immunophenotyping | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Multiple Myeloma - metabolism | Regulatory Factor X Transcription Factors | Proteasome Inhibitors - therapeutic use | Transcription Factors - metabolism | Activating Transcription Factor 6 - metabolism | Drug Resistance, Neoplasm - genetics | Endoplasmic Reticulum Stress | Mutation | Pyrazines - pharmacology | Multiple Myeloma - genetics | Boronic Acids - pharmacology | Immunoglobulins | Care and treatment | Multiple myeloma | Genetic research | Health aspects | Tumors | Cancer
Journal Article
Journal Article
Journal Article