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Diabetes, ISSN 0012-1797, 11/2012, Volume 61, Issue 11, pp. 2881 - 2892
Macrophages are multifunctional immune cells that may either drive or modulate disease pathogenesis depending on their activation phenotype. Autoimmune type 1... 
ACTIVATION | TOLERANCE | QUANTIFICATION | INFLAMMATION | IN-VIVO | MOUSE | ENDOCRINOLOGY & METABOLISM | REGULATORY T-CELLS | ANTIGENS | IL-10 | BETA | Prediabetic State - metabolism | Macrophages - transplantation | Cell Proliferation | Lymph Nodes - pathology | Diabetes Mellitus, Type 1 - prevention & control | Diabetes Mellitus, Type 1 - metabolism | RNA, Messenger - metabolism | Prediabetic State - therapy | Cell Tracking | Insulin-Secreting Cells - metabolism | Prediabetic State - immunology | Interleukin-10 - metabolism | Female | Prediabetic State - pathology | Diabetes Mellitus, Type 1 - immunology | Macrophages - immunology | Immunotherapy, Adoptive | Interferon-gamma Release Tests | Interleukin-4 - metabolism | Cells, Cultured | Diabetes Mellitus, Type 1 - pathology | Gene Expression Regulation | Lymph Nodes - metabolism | Pancreas - pathology | Mice, Transgenic | Lymph Nodes - immunology | Pancreas - metabolism | Pancreas - immunology | Insulin-Secreting Cells - immunology | Macrophage Activation | Macrophages - metabolism | Animals | Mice, Inbred NOD | Mice | Insulin-Secreting Cells - pathology | Transforming Growth Factor beta - metabolism | Research | Macrophages | Type 1 diabetes | Analysis | Index Medicus | Abridged Index Medicus | Immunology and Transplantation | Basic Medicine | Immunologi inom det medicinska området | Medical and Health Sciences | Medicin och hälsovetenskap | Immunology in the medical area | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Diabetes, ISSN 0012-1797, 02/2013, Volume 62, Issue 2, pp. 543 - 550
Journal Article
Journal Article
Diabetes, ISSN 0012-1797, 11/2012, Volume 61, Issue 11, pp. 2893 - 2905
For autoimmune conditions like type 1 diabetes to progress, self-reactive CD8(+) T cells would need to interact with peptide-antigen cross-presented on the... 
MHC CLASS-I | ANTIBODY PREVENTS | AUTOIMMUNE | NOD MICE | DENDRITIC CELLS | BETA-CELLS | ENDOCRINOLOGY & METABOLISM | IDENTIFICATION | DIABETOGENIC T-CELLS | LYMPHOCYTE DEPLETION | TRANSGENIC MICE | Prediabetic State - metabolism | Autoantigens - metabolism | CD8-Positive T-Lymphocytes - pathology | Cell Proliferation | Lymph Nodes - pathology | Coculture Techniques | Diabetes Mellitus, Type 1 - metabolism | CD4-Positive T-Lymphocytes - pathology | Autoantigens - adverse effects | CD4-Positive T-Lymphocytes - immunology | Antigen-Presenting Cells - pathology | Bone Marrow Transplantation - immunology | Antigen Presentation | Islets of Langerhans - metabolism | Prediabetic State - immunology | CD8-Positive T-Lymphocytes - metabolism | Female | Lymph Nodes - drug effects | Prediabetic State - pathology | B-Lymphocytes - pathology | Diabetes Mellitus, Type 1 - immunology | B-Lymphocytes - metabolism | Antigen-Presenting Cells - metabolism | Islets of Langerhans - pathology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Diabetes Mellitus, Type 1 - pathology | Islets of Langerhans - immunology | Pancreas - pathology | Lymph Nodes - immunology | Pancreas - metabolism | Pancreas - immunology | Antigen-Presenting Cells - immunology | Disease Progression | Mice, Knockout | Animals | B-Lymphocytes - immunology | Mice, Inbred NOD | Mice | CD8-Positive T-Lymphocytes - immunology | Chimera | Physiological aspects | Development and progression | B cells | Research | Diabetes | Analysis | Index Medicus | Abridged Index Medicus | Immunology and Transplantation
Journal Article
The Journal of Immunology, ISSN 0022-1767, 07/2001, Volume 167, Issue 2, pp. 1081 - 1089
B cells can serve dual roles in modulating T cell immunity through their potent capacity to present Ag and induce regulatory tolerance. Although B cells are... 
RESPONSES | DENDRITIC CELLS | TOLERANCE | FAS-LIGAND | IN-VIVO | DISEASE | CD4(+) T-CELLS | ANTIGEN-PRESENTING CELLS | IMMUNOLOGY | PEPTIDE | LYMPHOCYTES | T-Lymphocyte Subsets - immunology | Th1 Cells - pathology | Cell Communication - immunology | Spleen - immunology | Diabetes Mellitus, Type 1 - prevention & control | B-Lymphocyte Subsets - transplantation | Membrane Glycoproteins - biosynthesis | B-Lymphocyte Subsets - cytology | Adoptive Transfer | Th1 Cells - immunology | fas Receptor - metabolism | Antigen-Presenting Cells - pathology | Lymphocyte Activation - immunology | Leukocytes, Mononuclear - immunology | Prediabetic State - immunology | B-Lymphocyte Subsets - immunology | Female | Prediabetic State - pathology | Diabetes Mellitus, Type 1 - immunology | Lymphocyte Transfusion | Islets of Langerhans - pathology | Cell Separation | Diabetes Mellitus, Type 1 - pathology | Prediabetic State - prevention & control | Islets of Langerhans - immunology | Spleen - cytology | Mice, SCID | Antigen-Presenting Cells - immunology | Fas Ligand Protein | Animals | Apoptosis - immunology | T-Lymphocyte Subsets - pathology | B-Lymphocyte Subsets - metabolism | Down-Regulation - immunology | Autoantigens - immunology | Lipopolysaccharides - pharmacology | Leukocytes, Mononuclear - cytology | Ligands | Mice, Inbred NOD | Mice | Transforming Growth Factor beta - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2017, Volume 12, Issue 5, pp. e0178000 - e0178000
Type 2 diabetes mellitus (DM) is associated with the down modulation of Th1, Th2 and Th17 responses in latent Mycobacterium tuberculosis infection but the role... 
DIABETES-MELLITUS | INDIVIDUALS | CYTOKINES | T-CELL RESPONSES | MULTIDISCIPLINARY SCIENCES | HUMANS | IMPAIRED FASTING GLUCOSE | TH1 | CD8(+) T | Humans | Middle Aged | Antigens, Bacterial - immunology | Mycobacterium tuberculosis - immunology | Male | Th2 Cells - immunology | Latent Tuberculosis - immunology | Prediabetic State - complications | Th1 Cells - immunology | Case-Control Studies | CD4-Positive T-Lymphocytes - immunology | Prediabetic State - immunology | Latent Tuberculosis - complications | Th17 Cells - immunology | Adult | Female | Aged | CD8-Positive T-Lymphocytes - immunology | Cytokines - immunology | Complications and side effects | Tuberculosis | Immune response | Mycobacterium tuberculosis | Physiological aspects | Development and progression | Genetic aspects | Research | Prediabetic state | Cell culture | Peptides | CD8 antigen | Lung | Tissue culture | Cytotoxicity | Biochemistry | Glucose | Assaying | Blood | Risk factors | Alterations | Human immunodeficiency virus--HIV | Hemoglobin | Cross sections | Spleen | Antigens | Cytokines | Abnormalities | Cultures | Pools | Metabolism | Insulin | Interleukin 17 | Radiography | Urea | Dilution | Nephropathy | Interleukin 10 | Aerosols | Skin | Mice | Metabolic disorders | Biotechnology | Animal models | Transforming growth factor-b | Amino acids | Population studies | Viruses | Lymphocytes T | Infections | Immunology | Interleukin 2 | Lymphocytes | Modulation | Mathematical models | Age | Geographical distribution | Creatinine | Alanine | Complications | Diabetes mellitus | Blood cells | Immune response (cell-mediated) | Inflammation | CD4 antigen | Immune systems | Falling | Diabetes | Index Medicus | Human immunodeficiency virus | Risk | HIV
Journal Article
Journal Article
Journal Article
Diabetologia, ISSN 0012-186X, 7/2012, Volume 55, Issue 7, pp. 1937 - 1943
Seroconversion to islet autoantibodies precedes type 1 diabetes. This study aimed to identify periods of high seroconversion incidence, which could be targeted... 
Islet autoantibody | Medicine & Public Health | Human Physiology | Type 1 diabetes | Metabolic Diseases | Internal Medicine | Incidence | Islet autoantibody. type 1 diabetes | GLUTAMIC-ACID DECARBOXYLASE | DENDRITIC CELLS | APPEARANCE | GERMAN BABYDIAB | RISK | THYROID AUTOIMMUNITY | ANTIBODY STANDARDIZATION PROGRAM | SCHOOLCHILDREN | ENDOCRINOLOGY & METABOLISM | T-CELLS | PROGRESSION | Diabetes Mellitus, Type 1 - epidemiology | Prediabetic State - genetics | Autoantibodies - blood | Humans | Child, Preschool | Infant | Male | HLA-D Antigens - immunology | Polymerase Chain Reaction | Prediabetic State - immunology | Female | Diabetes Mellitus, Type 1 - immunology | Child | Prediabetic State - epidemiology | Genetic Predisposition to Disease | Child of Impaired Parents | HLA-D Antigens - genetics | Diabetes Mellitus, Type 1 - genetics | Genotype | Disease Progression | Germany - epidemiology | Autoantibodies - immunology | Adolescent | Age of Onset | Longitudinal Studies | Cohort Studies | Viral antibodies | Autoimmunity | Autoantibodies | Antibodies | Diabetes | Research | Juvenile offenders | Glutamate | Environmental health | Index Medicus | Risk groups | Diabetes mellitus | Glutamate decarboxylase | zinc transporter | Insulin | Seroconversion | Progeny | Histocompatibility antigen HLA | Children | Islets of Langerhans | Age | Genotypes | Thyroid
Journal Article