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Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 32, pp. 13168 - 13185
Cytochrome P450 (P450, CYP) 17A1 plays a critical role in steroid metabolism, catalyzing both the 17 alpha-hydroxylation of pregnenolone and progesterone and... 
HUMAN P450C17 | ACTIVE-SITE | ENZYMES | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROSTATE-CANCER | 17-ALPHA-HYDROXYLASE-17,20-LYASE CYP17 | INHIBITOR | MICROSOMAL CYTOCHROME-P-450 | ORTERONEL TAK-700 | ISOLATED 17,20-LYASE DEFICIENCY | Steroid 17-alpha-Hydroxylase - antagonists & inhibitors | NADPH-Ferrihemoprotein Reductase - genetics | Stereoisomerism | Humans | Imidazoles - chemistry | Cytochrome P-450 Enzyme Inhibitors - metabolism | Cytochromes b5 - metabolism | Androstenedione - metabolism | Cytochromes b5 - genetics | Pregnenolone - metabolism | Progesterone - chemistry | Biocatalysis - drug effects | Dehydroepiandrosterone - chemistry | Cytochrome P-450 Enzyme Inhibitors - chemistry | Dehydroepiandrosterone - metabolism | Naphthalenes - metabolism | Binding Sites | 17-alpha-Hydroxypregnenolone - metabolism | Imidazoles - metabolism | Naphthalenes - chemistry | Recombinant Proteins - metabolism | NADPH-Ferrihemoprotein Reductase - metabolism | Oxidation-Reduction | Models, Molecular | Rats | Recombinant Proteins - chemistry | Imidazoles - pharmacology | Naphthalenes - pharmacology | Cytochrome P-450 Enzyme Inhibitors - pharmacology | Animals | Progesterone - metabolism | Androstenedione - chemistry | Ligands | Pregnenolone - chemistry | Protein Conformation | Steroid 17-alpha-Hydroxylase - genetics | 17-alpha-Hydroxypregnenolone - chemistry | Steroid 17-alpha-Hydroxylase - metabolism | Kinetics | Steroid 17-alpha-Hydroxylase - chemistry | pre-steady-state kinetics | steroid metabolism | oxidation-reduction (redox) | steroidogenesis | cytochrome P450 | Enzymology | steady-state kinetics | enzyme kinetics
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2014, Volume 289, Issue 47, pp. 32952 - 32964
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Journal of The American Society for Mass Spectrometry, ISSN 1044-0305, 9/2012, Volume 23, Issue 9, pp. 1558 - 1568
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