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Research and Practice in Thrombosis and Haemostasis, ISSN 2475-0379, 10/2019, Volume 3, Issue 4, pp. 599 - 606
Factor XII (FXII) becomes a serine protease when blood is exposed to artificial medical surfaces or when pathologic surfaces arise in disease states leading to... 
C1 inhibitor | high‐molecular‐weight kininogen | contact activation | prekallikrein | factor XII | urokinase plasminogen activator receptor | Proteins | Medical equipment | Hypotheses | Wound healing | Dendritic cells | Neutrophils | Hemophilia | Bone marrow | Defense mechanisms | Inflammation | Thrombosis
Journal Article
Thrombosis Research, ISSN 0049-3848, 2019, Volume 182, pp. 89 - 94
AbstractIntroductionHigh molecular weight kininogen (HK) and prekallikrein (PK) are proteins in the kallikrein/kinin system of the coagulation cascade. They... 
Hematology, Oncology, and Palliative Medicine | Heart failure | Cardiovascular disease | Ischemic stroke | Prekallikrein | Prospective study | High molecular weight kininogen
Journal Article
Stroke, ISSN 0039-2499, 08/2019, Volume 50, Issue 8, pp. 2181 - 2186
BACKGROUND AND PURPOSE—Hypercoagulable states in migraine patients may play a role in the pathophysiology underlying the association between migraine and... 
SYSTEM | ACTIVATION | blood coagulation | history | PREVALENCE | MIGRAINE | CLINICAL NEUROLOGY | DISEASE | THROMBOPHILIA | PERIPHERAL VASCULAR DISEASE | risk | headache | prekallikrein | YOUNG-WOMEN | BURDEN | AURA | BLOOD
Journal Article
Communications in Statistics - Theory and Methods, ISSN 0361-0926, 06/2019, Volume 48, Issue 12, pp. 2982 - 3004
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 6/2019, Volume 53, Issue 3, pp. 267 - 271
Method development for determining prekallikrein activator in medicinal preparations of human immunoglobulins and albumin found that the adequacy of... 
human albumin preparations | human immunoglobulin preparations for intravenous injection | Pharmacy | prekallikrein activator | Pharmacology/Toxicology | Organic Chemistry | specific safety | CHEMISTRY, MEDICINAL | PHARMACOLOGY & PHARMACY | STANDARD | Albumin | Kallikrein | Usage | Methods
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 05/2019, Volume 119, Issue 5, pp. 834 - 843
Abstract The kallikrein/kinin system, an intravascular biochemical pathway that includes several proteins involved in the contact activation system of... 
Stroke, Systemic or Venous Thromboembolism | ACTIVATION | DESIGN | THROMBOSIS | ATHEROSCLEROSIS RISK | pulmonary embolus | FACTOR-XI | prospective study | INFLAMMATION | high molecular weight kininogen | COAGULATION | PERIPHERAL VASCULAR DISEASE | COHORT | MICE | prekallikrein | HEMATOLOGY | venous thrombosis
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 05/2019, Volume 17, Issue 5, pp. 759 - 770
Journal Article
Journal of Structural Biology, ISSN 1047-8477, 05/2019, Volume 206, Issue 2, pp. 170 - 182
Plasma kallikrein (pKal) is a serine protease responsible for cleaving high-molecular-weight kininogen to produce the pro-inflammatory peptide, bradykinin.... 
Binding mode | Serine protease | Small molecule | Inhibition | Plasma kallikrein | SYSTEM | DOMAIN | HEREDITARY ANGIOEDEMA | MOLECULAR-WEIGHT KININOGEN | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | PROPHYLAXIS | BIOPHYSICS | FACTOR-XI | BINDING-SITE | SERINE-PROTEASE | ZYMOGEN | PREKALLIKREIN | Kallikrein | Structure | Bradykinin | Analysis | Crystals
Journal Article
Standartnye Obrazcy, ISSN 2077-1177, 04/2019, Volume 14, Issue 3-4, pp. 33 - 41
Human immunoglobulin and human albumin products can negatively affect patients’ health. The residual content of haemagglutinins, anti-D antibodies,... 
anti-A and anti-B haemagglutinins | quality control | human albumin products | prekallikrein activator | reference materials | hemagglutination methods | human immunoglobulin products | complement fixation test | chromogenic assay | anti-D antibodies | anticomplementary activity | specific safety
Journal Article
Nucleic Acid Therapeutics, ISSN 2159-3337, 04/2019, Volume 29, Issue 2, pp. 82 - 91
Kallikrein is the key contact system mediator responsible for the conversion of high-molecular-weight kininogen into the inflammatory vasodilator peptide... 
hereditary angioedema | antisense oligonucleotide | plasma prekallikrein
Journal Article
BLOOD, ISSN 0006-4971, 03/2019, Volume 133, Issue 10, pp. 1152 - 1163
The plasma proteins factor XII (FXII) and prekallikrein (PK) undergo reciprocal activation to the proteases FXIIa and kallikrein by a process that is enhanced... 
KALLIKREIN | PATHOGENESIS | PLASMA PREKALLIKREIN | THROMBOSIS | MUTATION | COAGULATION | UPDATE | CONTACT ACTIVATION | HEMATOLOGY | PLASMINOGEN | DELETION
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 01/2019, Volume 17, Issue 1, pp. 157 - 168
Journal Article
Virulence, ISSN 2150-5594, 12/2018, Volume 9, Issue 1, pp. 248 - 261
Streptococcus gallolyticus subsp. gallolyticus, formerly classified as S. bovis biotype I, is an increasing cause of bacteremia and infective endocarditis in... 
bradykinin | pili | endocarditis | contact system | Streptococcus gallolyticus | Pili | Bradykinin | Contact system | Endocarditis | INFECTIOUS DISEASES | HUMAN NEUTROPHILS | PROTEIN | KININOGENS | MICROBIOLOGY | IMMUNOLOGY | IDENTIFICATION | PYOGENES | INFECTIVE ENDOCARDITIS | BOVIS/STREPTOCOCCUS-EQUINUS COMPLEX | EXPRESSION | INNATE IMMUNITY
Journal Article
Ochsner Journal, ISSN 1524-5012, 12/2018, Volume 18, Issue 4, pp. 423 - 424
Prekallikrein deficiency is an extremely rare disorder in which functional prekallikrein in the plasma is reduced or absent. We present the case of a... 
Prekallikrein deficiency | Prekallikrein | Factor XIIa | prekallikrein deficiency | prekallikrein | Case Reports and Clinical Observations
Journal Article
Blood Reviews, ISSN 0268-960X, 11/2018, Volume 32, Issue 6, pp. 433 - 448
Journal Article