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Blood, ISSN 0006-4971, 03/2009, Volume 113, Issue 12, pp. 2619 - 2628
Children with Down syndrome (DS) show a spectrum of clinical anomalies, including cognitive impairment, cardiac malformations, and craniofacial dysmorphy.... 
TRANSIENT MYELOPROLIFERATIVE DISORDER | ACUTE LYMPHOBLASTIC-LEUKEMIA | TRANSCRIPTION FACTOR GABP | HEMATOPOIETIC STEM-CELLS | MOUSE MODEL | ACUTE MEGAKARYOBLASTIC LEUKEMIA | ACUTE MYELOID-LEUKEMIA | HIGH CURE RATE | SYNDROME PHENOTYPES | ACUTE MEGAKARYOCYTIC LEUKEMIA | HEMATOLOGY | Liver - pathology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - epidemiology | Humans | Hematopoiesis, Extramedullary - genetics | Liver - embryology | Myeloproliferative Disorders - genetics | Incidence | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Cell Transformation, Neoplastic - genetics | Preleukemia - genetics | Down Syndrome - blood | Down Syndrome - complications | Myeloproliferative Disorders - epidemiology | Preleukemia - epidemiology | Leukemia, Megakaryoblastic, Acute - genetics | Neoplasm Proteins - genetics | Myeloproliferative Disorders - congenital | Disease Models, Animal | Preleukemia - etiology | Genetic Predisposition to Disease | Janus Kinases - genetics | Leukemia, Megakaryoblastic, Acute - etiology | Leukemia, Megakaryoblastic, Acute - epidemiology | Myeloproliferative Disorders - drug therapy | Gene Expression Regulation, Leukemic | Preleukemia - drug therapy | Chromosomes, Human, Pair 21 - genetics | Disease Progression | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Preleukemia - congenital | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Down Syndrome - genetics | GATA1 Transcription Factor - genetics | RNA, Neoplasm - genetics | Myeloproliferative Disorders - etiology | Leukemia, Megakaryoblastic, Acute - drug therapy | Mice | MicroRNAs - genetics | Mutation | Precursor Cell Lymphoblastic Leukemia-Lymphoma - etiology | Review
Journal Article
2003, Hematology/oncology clinics of North America, Volume 17, no. 5., xxii, p. 1095-1275
Book
Journal Article
Leukemia, ISSN 0887-6924, 2012, Volume 26, Issue 6, pp. 1286 - 1292
Journal Article
Blood, ISSN 0006-4971, 2013, Volume 122, Issue 24, pp. 3908 - 3917
Journal Article
Science, ISSN 0036-8075, 1/2008, Volume 319, Issue 5861, pp. 336 - 339
Understanding cancer pathogenesis requires knowledge of not only the specific contributory genetic mutations but also the cellular framework in which they... 
Medical research | Cord blood | B lymphocytes | Blood cells | Leukemia | Stem cells | Childhood | Bone marrow | Reports | Twins | Blood | STEM-CELLS | LESSONS | IDENTIFICATION | MULTIDISCIPLINARY SCIENCES | ADP-ribosyl Cyclase 1 - analysis | Neoplasm Transplantation | Antigens, CD34 - analysis | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Diseases in Twins - genetics | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Humans | Preleukemia - pathology | Child, Preschool | Male | Transplantation, Heterologous | Core Binding Factor Alpha 2 Subunit - analysis | Core Binding Factor Alpha 2 Subunit - physiology | Oncogene Proteins, Fusion - analysis | Oncogene Proteins, Fusion - physiology | Preleukemia - genetics | Recombination, Genetic | Bone Marrow Transplantation | Neoplastic Stem Cells - pathology | Female | Acute Disease | Antigens, CD19 - analysis | Fetal Blood - transplantation | Mice, SCID | Twins, Monozygotic | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Preleukemia - metabolism | Animals | Gene Rearrangement, B-Lymphocyte, Heavy Chain | Oncogene Proteins, Fusion - genetics | Diseases in Twins - metabolism | Precursor Cells, B-Lymphoid - chemistry | Mice, Inbred NOD | Mice | Precursor Cells, B-Lymphoid - physiology | Core Binding Factor Alpha 2 Subunit - genetics | Diseases in Twins - pathology | Apoptosis | Genetic aspects | Research | Lymphocytic leukemia | Carcinogenesis | Leukemia in children | Biomedical research | Cellular biology | Rodents | Genetics | Mutation | Children & youth
Journal Article
Pediatric Clinics of North America, ISSN 0031-3955, 02/2015, Volume 62, Issue 1, pp. 121 - 137
Journal Article
Science, ISSN 0036-8075, 2/2010, Volume 327, Issue 5967, pp. 879 - 883
The LMO2 oncogene causes a subset of human T cell acute lymphoblastic leukemias (T-ALL), including four cases that arose as adverse events in gene therapy... 
Transcription factors | Thymocytes | Transgenic animals | Acute T cell leukemia | Genes | Leukemia | Reports | Mice | Progenitor cells | Hematopoietic stem cells | Oncogenes | CHROMOSOMAL TRANSLOCATIONS | ACTIVATION | HEMATOPOIESIS | SCID-X1 | MULTIDISCIPLINARY SCIENCES | ACUTE LYMPHOBLASTIC-LEUKEMIA | TRANSCRIPTION | T-CELL LEUKEMIA | GENE-THERAPY | PROTEIN RBTN2 | RETROVIRAL INSERTION | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - pathology | T-Lymphocytes - physiology | Up-Regulation | Oligonucleotide Array Sequence Analysis | Humans | Preleukemia - pathology | Gene Expression Profiling | T-Lymphocytes - transplantation | DNA-Binding Proteins - metabolism | Metalloproteins - metabolism | Cell Transformation, Neoplastic - genetics | Preleukemia - genetics | Metalloproteins - genetics | Thymus Gland - pathology | Transcription, Genetic | Cell Differentiation | Proto-Oncogene Proteins | Thymus Gland - metabolism | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | T-Lymphocyte Subsets | Precursor Cells, T-Lymphoid - physiology | LIM Domain Proteins | Down-Regulation | Mice, Transgenic | Gene Expression Regulation, Leukemic | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Preleukemia - metabolism | Adaptor Proteins, Signal Transducing | Animals | Precursor Cells, T-Lymphoid - transplantation | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Development and progression | Thymoma | Properties | Cancer cells | Mutation | Cellular biology | Gene expression | Lymphocytes | Rodents
Journal Article
Science Translational Medicine, ISSN 1946-6234, 08/2012, Volume 4, Issue 149, pp. 149ra118 - 149ra118
Journal Article