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Neurobiology of aging, ISSN 0197-4580, 2020, Volume 86, pp. 156 - 161
Presenilin 1 (PS1), the catalytic component of gamma secretase, associates with synaptotagmin 1 (Syt-1... 
Aging | Gamma secretase | Neuroscience | Synaptotagmin 1 | Presenilin 1 | Alzheimer's disease | ALZHEIMERS-DISEASE | SYNAPSE | SENSOR | NEUROSCIENCES | GERIATRICS & GERONTOLOGY | MEMORY | CORTEX | CA2 | CALCIUM
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 12/2010, Volume 107, Issue 50, pp. 21435 - 21440
Journal Article
Redox biology, ISSN 2213-2317, 2015, Volume 4, Issue C, pp. 6 - 13
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2000, Volume 97, Issue 11, pp. 6138 - 6143
Journal Article
Journal Article
Journal Article
Frontiers in molecular neuroscience, ISSN 1662-5099, 2017, Volume 10, p. 291
... the presenilin 1 mutation A246E. Mitophagy impairment was observed due to a diminished autophagy degradation phase associated with lysosomal anomalies, thus causing the accumulation of dysfunctional mitochondria labeled by Parkin... 
Fibroblasts | Presenilin 1 mutation | IPSC derived neurons | Alzheimer’s disease | Mitophagy | OXIDATIVE STRESS | HOMEOSTASIS | MITOCHONDRIA | P62/SQSTM1 | ACIDIFICATION | presenilin 1 mutation | AUTOPHAGY | NEUROSCIENCES | iPSC derived neurons | PARKIN | mitophagy | fibroblasts | DEGRADATION | DYSFUNCTION | Alzheimer's disease | EXPRESSION | Peptides | Cloning | Acidification | Kinases | Patients | Autophagy | Mitochondria | Presenilin 1 | Penicillin | Stem cells | Mutation | Recycling | Adapter proteins | Pluripotency | Phagocytosis
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 11/2013, Volume 288, Issue 44, pp. 32050 - 32063
Journal Article
Pharmaceutical research, ISSN 1573-904X, 2018, Volume 36, Issue 1, pp. 1 - 8
The study aim was to evaluate the effect of Alzheimer’s disease (AD) and inflammatory insult on the function of L-type amino acid transporter 1 (Lat1... 
Biochemistry, general | alzheimer’s disease | blood-brain barrier | L-type amino acid transporter | Biomedicine | Pharmacy | Medical Law | Pharmacology/Toxicology | Biomedical Engineering and Bioengineering | CNS drug delivery | alzheimer's disease | AUGMENTATION | GABAPENTIN | CHEMISTRY, MULTIDISCIPLINARY | LAT1 | DRUG EFFICACY | PHARMACOKINETICS | PHARMACOLOGY & PHARMACY | INHIBITOR | EXPRESSION | Lipopolysaccharides - toxicity | Large Neutral Amino Acid-Transporter 1 - metabolism | Mice, Inbred C57BL | Astrocytes - pathology | Encephalitis - pathology | Presenilin-1 - genetics | Mice, Transgenic | Imidazoles - pharmacology | RNA, Messenger - metabolism | Blood-Brain Barrier - drug effects | Alzheimer Disease - pathology | Blood-Brain Barrier - metabolism | Blood-Brain Barrier - pathology | Amyloid beta-Protein Precursor - genetics | Animals | Mice | Pyridines - pharmacology | Encephalitis - chemically induced | Large Neutral Amino Acid-Transporter 1 - physiology | Mutation | Primary Cell Culture | Alzheimer Disease - genetics | Astrocytes - metabolism | Disease Models, Animal | Drugs | Drug delivery systems | RNA | Amino acids | Genetic aspects | Genetic engineering | Alzheimer's disease | Mitogens | Central nervous system agents | Vehicles | L-leucine | mRNA | Leucine | LAT1 protein | Lipopolysaccharides | Proteins | Blood-brain barrier | Protein folding | Rodents | Carbon 14 |