X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (4460) 4460
Publication (678) 678
Newsletter (187) 187
Book Chapter (106) 106
Book Review (92) 92
Newspaper Article (33) 33
Book / eBook (24) 24
Conference Proceeding (19) 19
Dissertation (13) 13
Magazine Article (8) 8
Trade Publication Article (4) 4
Web Resource (2) 2
Government Document (1) 1
Report (1) 1
Streaming Video (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (2505) 2505
index medicus (2165) 2165
humans (1998) 1998
prion protein (1547) 1547
prions (1471) 1471
mice (1370) 1370
biochemistry & molecular biology (1156) 1156
neurosciences (1129) 1129
proteins (1050) 1050
nervous system diseases (831) 831
prions - metabolism (791) 791
prion (755) 755
cell biology (710) 710
alzheimers-disease (655) 655
scrapie (637) 637
alzheimer's disease (601) 601
creutzfeldt-jakob-disease (588) 588
animal diseases (574) 574
research (566) 566
neurodegeneration (526) 526
brain (509) 509
prion diseases (491) 491
prions - genetics (486) 486
neurons (445) 445
analysis (440) 440
creutzfeldt-jakob disease (437) 437
cellular prion protein (432) 432
neurodegenerative diseases (431) 431
prp (407) 407
female (406) 406
expression (403) 403
physiological aspects (388) 388
biology (386) 386
disease (385) 385
protein folding (374) 374
male (369) 369
prion diseases - metabolism (365) 365
protein binding (361) 361
multidisciplinary sciences (359) 359
prions - chemistry (342) 342
prpc proteins - metabolism (340) 340
article (333) 333
pathology (328) 328
neurology (327) 327
mice, inbred c57bl (324) 324
research article (324) 324
brain - metabolism (321) 321
protein (321) 321
neurons - metabolism (320) 320
mutation (311) 311
transgenic mice (298) 298
signal transduction (297) 297
apoptosis (292) 292
gene expression (291) 291
cells (287) 287
medicine (282) 282
oxidative stress (280) 280
nervous system (270) 270
cells, cultured (265) 265
peptides (265) 265
brain - pathology (261) 261
immunology (260) 260
pathogenesis (255) 255
clinical neurology (252) 252
amino acid sequence (251) 251
biophysics (248) 248
molecular sequence data (247) 247
in-vitro (246) 246
mice, transgenic (246) 246
life sciences (244) 244
disease models, animal (243) 243
mice, knockout (243) 243
neurotoxicity (242) 242
genetic aspects (241) 241
health aspects (241) 241
prion diseases - pathology (231) 231
cell line (227) 227
prion disease (225) 225
prpsc proteins - metabolism (225) 225
biochemistry (223) 223
in-vivo (221) 221
amyloid (220) 220
oligomers (219) 219
bovine spongiform encephalopathy (218) 218
central-nervous-system (213) 213
science (209) 209
alzheimer disease - metabolism (208) 208
mental disorders (206) 206
rats (206) 206
binding (204) 204
amyloid beta-peptides - metabolism (198) 198
alpha-synuclein (196) 196
parkinsons-disease (196) 196
review (193) 193
protein conformation (192) 192
alzheimers disease (191) 191
development and progression (188) 188
infectious diseases (182) 182
medical research (181) 181
cancer (180) 180
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (4757) 4757
French (7) 7
Japanese (6) 6
Spanish (4) 4
German (3) 3
Portuguese (3) 3
Polish (2) 2
Chinese (1) 1
Italian (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature, ISSN 0028-0836, 08/2016, Volume 536, Issue 7617, pp. 464 - 468
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 02/2007, Volume 402, Issue 1, pp. 17 - 23
PrPC (cellular prion protein) is located at the surface of neuronal cells in detergent-insoluble lipid rafts, yet is internalized by clathrin-dependent... 
Receptor-associated protein (RAP) | Clathrin | Low-density lipoprotein receptor-related protein-1 (LRP1) | Prion | dependent endocytosis | Amyloid precursor protein (APP) | receptor-associated protein (RAP) | clathrin | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | Cu2+ dependent endocytosis | low-density lipoprotein receptor-related protein-1 (LRP1) | AMYLOID PRECURSOR PROTEIN | amyloid precursor protein (APP) | INTERNALIZATION | METABOLISM | LIPID RAFTS | SURFACE | prion | GENE FAMILY | DEGRADATION | BINDING | UROKINASE | Receptors, LDL - genetics | Humans | Low Density Lipoprotein Receptor-Related Protein-1 - metabolism | Receptors, LDL - metabolism | Low Density Lipoprotein Receptor-Related Protein-1 - genetics | Clathrin - metabolism | Endocytosis | Animals | Amyloid beta-Protein Precursor - metabolism | Copper - metabolism | Ligands | Mice | Neuroblastoma - metabolism | Neurons - metabolism | PrPC Proteins - metabolism | Tumor Cells, Cultured | PrPC Proteins - genetics | LDL-Receptor Related Protein-Associated Protein - metabolism | Microscopy, Fluorescence | RNA, Small Interfering - metabolism | Cu2+-dependent endocytosis | uPA, urokinase-type plasminogen activator | GPI, glycosyl-phosphatidylinositol | uPAR, uPA receptor | Accelerated Publication | RAP, receptor-associated protein | LRP, LDL receptor-related protein | PAI-1, plasminogen activator inhibitor-1 | PrPSc, infectious form of the prion protein | siRNA, small interfering RNA | HSPG, heparin sulfate proteoglycan | HRP, horseradish peroxidase | KPI, Kunitz-type protease inhibitor | LDL, low-density lipoprotein | APP, amyloid precursor protein | PrPC, cellular form of the prion protein
Journal Article
Frontiers in Aging Neuroscience, ISSN 1663-4365, 2014, Volume 6, Issue MAY, p. 93
Accumulation and aggregation of amyloid-beta (A beta) peptides in the brain trigger the development of progressive neurodegeneration and dementia associated... 
LRP1 | Apolipoprotein E | amyloid-β | signaling pathway | clearance | endocytosis | degradation | Alzheimer's disease | COMMON VARIANTS | HUMAN APOLIPOPROTEIN-E | PLASMA-MEMBRANE | NEUROSCIENCES | GERIATRICS & GERONTOLOGY | amyloid-beta | PRION PROTEIN | IN-VITRO | IDENTIFIES VARIANTS | APOPTOTIC CELLS | apolipoprotein E | A-BETA | PRECURSOR PROTEIN | GENOME-WIDE ASSOCIATION
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 02/2017, Volume 483, Issue 4, pp. 1143 - 1147
Soluble oligomers of amyloid-beta (Aβo) are implicated by biochemical and genetic evidence as a trigger for Alzheimer's disease (AD) pathophysiology. A key... 
Cellular prion protein | Alzheimer's disease | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEMORY IMPAIRMENT | KINASE | METABOTROPIC GLUTAMATE | SYNAPTIC PLASTICITY | INHIBITION | BIOPHYSICS | ASSEMBLIES | IN-VIVO | A-BETA | FYN | MICE | Animals | Signal Transduction | Humans | Amyloid beta-Peptides - metabolism | Protein Binding | Mice | PrPC Proteins - metabolism | Index Medicus
Journal Article
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 01/2011, Volume 25, Issue 1, pp. 265 - 279
The prion protein (PrPC) is highly expressed in the nervous system, and its abnormal conformer is associated with prion diseases. PrPC is anchored to cell... 
signal transduction | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | G-coupled protein receptors | PROMOTING DOMAIN | KDI-DOMAIN | TRAFFICKING | IDENTIFICATION | GPI-anchored proteins | STRESS-INDUCIBLE PROTEIN-1 | CELL BIOLOGY | INTERNALIZATION | CELLULAR PRION | CALCIUM | BIOLOGY | multiprotein complexes | neurotrophic signals | DIFFERENTIATION
Journal Article
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, ISSN 0022-3069, 10/2006, Volume 65, Issue 10, pp. 964 - 975
Prion diseases are characterized by neuronal loss, astrocytic gliosis, spongiform change, and abnormal protease-resistant prion protein (PrPres) deposition.... 
CELLS | bovine spongiform encephalopathy | ALZHEIMERS-DISEASE | Creutzfeldt-Jakob disease | ADENOSINE-A1-RECEPTOR | PATHOLOGY | NEUROSCIENCES | NEUROPROTECTION | CLINICAL NEUROLOGY | PRION PROTEIN | MULTIPLE-SCLEROSIS | bovine-PrP transgenic mice | adenosine receptor | prion | RAT HIPPOCAMPUS | BRAIN | MODULATION | TRANSGENIC MICE
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2016, Volume 291, Issue 33, pp. 17112 - 17121
The dysfunction and loss of synapses in Alzheimer disease are central to dementia symptoms. We have recently demonstrated that pathological Amyloid oligomer... 
metabotropic glutamate receptor (mGluR) | pyk2 | Alzheimer disease | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEMORY IMPAIRMENT | SYNAPTIC PLASTICITY | calmodulin-dependent protein kinase II (CaMKII) | BETA OLIGOMERS | amyloid | OPERATED CALCIUM-ENTRY | Ca2 | HOMER-PROTEINS | A-BETA | NEURONS | prion | MICE | FYN | TRANSGENIC MOUSE MODEL | homer
Journal Article
Biochemical and biophysical research communications, ISSN 0006-291X, 2/2017, Volume 483, Issue 4, pp. 1143 - 1147
Soluble oligomers of amyloid-beta (Aβo) are implicated by biochemical and genetic evidence as a trigger for Alzheimer’s disease (AD) pathophysiology. A key... 
Prnp = prion gene name | Alzheimer’s disease | cellular prion protein | PrPC = cellular prion protein | Aβo = amyloid-beta oligomers | Aβ = amyloid-beta
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 02/2017, Volume 483, Issue 4, p. 1143
Soluble oligomers of amyloid-beta (A[beta]o) are implicated by biochemical and genetic evidence as a trigger for Alzheimer's disease (AD) pathophysiology. A... 
Oligomers | Medical colleges | Neurosciences | Analysis | Prions | Cellular signal transduction | Glutamate | Mediation | Alzheimer's disease | Neurons
Journal Article
Frontiers in Cellular Neuroscience, ISSN 1662-5102, 07/2019, Volume 13
The pathological features of Alzheimer’s disease (AD) include senile plaques induced by amyloid-β (Aβ) protein deposits, neurofibrillary tangles formed by... 
Brain | Disease | Pathogenesis | Cognitive ability | Proteins | Pathology | Neurotoxicity | Hypotheses | Neurofibrillary tangles | Senile plaques | Tau protein | Prion protein | Alzheimer's disease | Binding sites | amyloid-β | receptor | cellular prion protein | Alzheimer’s disease | oligomers
Journal Article