X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (1228) 1228
Publication (327) 327
Book Review (6) 6
Book Chapter (3) 3
Dissertation (3) 3
Book / eBook (1) 1
Conference Proceeding (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (1084) 1084
male (615) 615
pro-opiomelanocortin - metabolism (609) 609
index medicus (568) 568
pro-opiomelanocortin - genetics (539) 539
mice (517) 517
rats (446) 446
endocrinology & metabolism (411) 411
hormones, hormone substitutes, and hormone antagonists (386) 386
neurosciences (331) 331
humans (314) 314
female (303) 303
endocrine system (288) 288
hypothalamus - metabolism (276) 276
food-intake (266) 266
digestive, oral, and skin physiology (256) 256
arcuate nucleus (241) 241
neurons - metabolism (234) 234
proopiomelanocortin (233) 233
hypothalamus (231) 231
nervous system (230) 230
leptin (220) 220
obesity (219) 219
neurons (203) 203
rats, sprague-dawley (190) 190
pro-opiomelanocortin (184) 184
rna, messenger - metabolism (181) 181
article (180) 180
mice, inbred c57bl (179) 179
intermedin (170) 170
brain (164) 164
agouti-related protein (152) 152
beta-endorphin (151) 151
gene-expression (150) 150
gene expression (146) 146
pomc (143) 143
body-weight (142) 142
neuropeptide-y (140) 140
hypothalamus - drug effects (135) 135
neuropeptide y - metabolism (134) 134
messenger-rna (125) 125
arcuate nucleus of hypothalamus - metabolism (124) 124
expression (124) 124
mice, knockout (121) 121
pro-opiomelanocortin - biosynthesis (121) 121
cell biology (116) 116
physiological aspects (116) 116
physiology (113) 113
pro-opiomelanocortin - physiology (112) 112
neuropeptide y (110) 110
melanocyte-stimulating hormone (108) 108
neurons - drug effects (108) 108
mice, transgenic (107) 107
biochemistry & molecular biology (102) 102
neuropeptide y - genetics (102) 102
research article (101) 101
eating - drug effects (97) 97
food intake (96) 96
rats, wistar (95) 95
research (95) 95
body weight (93) 93
energy homeostasis (93) 93
central-nervous-system (91) 91
rodents (91) 91
homeostasis (89) 89
pituitary gland - metabolism (89) 89
neurons - physiology (87) 87
agouti-related protein - metabolism (86) 86
in situ hybridization (85) 85
multidisciplinary sciences (84) 84
hypothalamus - cytology (83) 83
obesity - metabolism (82) 82
paraventricular nucleus (81) 81
acth (80) 80
leptin - metabolism (80) 80
rna, messenger - analysis (79) 79
rna, messenger - genetics (79) 79
alpha-msh - metabolism (78) 78
insulin (78) 78
signal transduction (78) 78
corticotropin-releasing hormone (77) 77
receptor (76) 76
receptors (76) 76
eating - physiology (75) 75
gene expression regulation - drug effects (75) 75
peptides (75) 75
pharmacology & pharmacy (74) 74
abridged index medicus (73) 73
energy metabolism - physiology (72) 72
time factors (72) 72
immunohistochemistry (70) 70
energy metabolism (69) 69
melanocortin (69) 69
adrenocorticotropic hormone - metabolism (68) 68
body weight - drug effects (66) 66
cells, cultured (66) 66
rat (66) 66
gene expression regulation (65) 65
dose-response relationship, drug (64) 64
hypothalamus - physiology (64) 64
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Biochemistry, ISSN 0006-2960, 06/2010, Volume 49, Issue 22, pp. 4583 - 4600
The melanocortin-4 receptor (MC4R) is a G-protein-coupled receptor (GPCR) that is expressed in the central nervous system and has a role in regulating feeding... 
GENE-MUTATIONS | ALPHA-MELANOTROPIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-SURFACE EXPRESSION | INVERSE AGONIST | MC4R MUTATIONS | MOLECULAR-CLONING | FUNCTIONAL-CHARACTERIZATION | TETRAPEPTIDE AC-HIS-DPHE-ARG-TRP-NH2 | STIMULATING HORMONE | CHILDHOOD OBESITY | Protein Binding - genetics | alpha-MSH - pharmacology | gamma-MSH - pharmacology | Humans | Molecular Sequence Data | Male | Receptor, Melanocortin, Type 4 - biosynthesis | Obesity - genetics | Pro-Opiomelanocortin - physiology | alpha-MSH - metabolism | beta-MSH - pharmacology | beta-MSH - metabolism | Protein Binding - drug effects | Agouti-Related Protein - antagonists & inhibitors | Amino Acid Sequence | Cell Line | Receptor, Melanocortin, Type 4 - antagonists & inhibitors | gamma-MSH - metabolism | Mutagenesis, Site-Directed | Receptor, Melanocortin, Type 4 - agonists | Receptor, Melanocortin, Type 4 - genetics | Pro-Opiomelanocortin - antagonists & inhibitors | Agouti-Related Protein - metabolism | Obesity - metabolism | Polymorphism, Genetic | Binding, Competitive - drug effects | Gene Expression Regulation - drug effects | Agouti-Related Protein - biosynthesis | Agouti-Related Protein - physiology | Pro-Opiomelanocortin - agonists | Pro-Opiomelanocortin - biosynthesis | alpha-MSH - physiology | Binding, Competitive - genetics | Ligands | alpha-MSH - analogs & derivatives | Antagonists (Biochemistry) | Proteins | Gene mutations | Analysis | Chemical properties | Single nucleotide polymorphisms | Structure
Journal Article
Endocrinology, ISSN 0013-7227, 01/2018, Volume 159, Issue 1, pp. 119 - 131
Critical windows of development are often more sensitive to endocrine disruption. The murine pituitary gland has two critical windows of development: embryonic... 
MOUSE PITUITARY | IN-VITRO | FEMALE RATS | PERINATAL EXPOSURE | ESTROGEN-RECEPTOR-ALPHA | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | HPA AXIS | SEX-DIFFERENCES | BRAIN | GLAND | Neurons - pathology | Receptors, Estrogen - metabolism | Transcription Factor Pit-1 - metabolism | Pituitary Gland - metabolism | Benzhydryl Compounds - toxicity | Phenols - toxicity | Male | Dose-Response Relationship, Drug | Transcription Factor Pit-1 - genetics | Female | Neurons - metabolism | Neurons - drug effects | Pro-Opiomelanocortin - genetics | Sexual Development - drug effects | Transcription Factor Pit-1 - antagonists & inhibitors | Organ Culture Techniques | Animals, Newborn | Pituitary Gland - pathology | Gene Expression Regulation, Developmental - drug effects | Receptors, Estrogen - antagonists & inhibitors | Pro-Opiomelanocortin - antagonists & inhibitors | Random Allocation | Sex Characteristics | Mice, Inbred Strains | Organ Specificity | Endocrine Disruptors - toxicity | Pro-Opiomelanocortin - metabolism | Organ Size - drug effects | Animals | Receptors, Estrogen - chemistry | Pituitary Gland - drug effects | Endocrine disruptors | Neonates | Estrogens | Menopause | Sex | Pituitary (anterior) | Exposure | Males | Gene expression | Dosage | Estradiol | Embryonic growth stage | Proteins | Bisphenol A | Organic chemistry | Sex hormones | Embryogenesis | Pit1 protein | Pituitary | Phenols | Pituitary gland | Disruption | Females
Journal Article
Neuron, ISSN 0896-6273, 02/2012, Volume 73, Issue 3, pp. 511 - 522
AgRP neuron activity drives feeding and weight gain whereas that of nearby POMC neurons does the opposite. However, the role of excitatory glutamatergic input... 
POMC NEURONS | GLUCOSE-HOMEOSTASIS | OBESITY | ENERGY-EXPENDITURE | WEIGHT HOMEOSTASIS | SK CHANNELS | ARCUATE NUCLEUS | HYPOTHALAMIC NEURONS | NEUROSCIENCES | TERM SYNAPTIC PLASTICITY | NEUROPEPTIDE-Y | Membrane Potentials - genetics | Age Factors | Nerve Tissue Proteins - deficiency | 2-Amino-5-phosphonovalerate - pharmacology | Male | Neurons - cytology | Green Fluorescent Proteins - genetics | Neuropeptide Y - genetics | Excitatory Postsynaptic Potentials - drug effects | Eating - physiology | Time Factors | Body Composition - drug effects | Dendritic Spines - drug effects | Body Composition - genetics | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Female | Agouti-Related Protein - deficiency | Energy Metabolism - genetics | Neurons - drug effects | Pro-Opiomelanocortin - genetics | Excitatory Postsynaptic Potentials - genetics | Membrane Potentials - drug effects | Brain - cytology | Fasting | Gene Expression Regulation - genetics | Dendritic Spines - physiology | Proto-Oncogene Proteins c-fos - metabolism | Mice, Transgenic | Excitatory Amino Acid Antagonists - pharmacology | Agouti-Related Protein - metabolism | Nerve Tissue Proteins - genetics | GABA Antagonists - pharmacology | Gene Expression Regulation - drug effects | Carrier Proteins - genetics | Eating - drug effects | Patch-Clamp Techniques | Animals | Picrotoxin - pharmacology | Receptors, N-Methyl-D-Aspartate - deficiency | Mice | In Vitro Techniques | RNA, Messenger | Energy Metabolism - drug effects | Neuropeptide Y | Methyl aspartate | Messenger RNA | Neurons | RNA | Genetic engineering | Kinases | Rodents | Food
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/2010, Volume 30, Issue 4, pp. 1560 - 1565
Leptin can exert its potent appetite-suppressing effects via activation of hypothalamic proopiomelanocortin (POMC) neurons. It depolarizes POMC neurons via... 
RECEPTOR POTENTIAL CHANNELS | PHOSPHOLIPASE-C-GAMMA | NEUROSCIENCES | BRAIN | CATION CHANNEL | Flufenamic Acid - pharmacology | TRPC Cation Channels - drug effects | Calcium Signaling - physiology | Leptin - metabolism | Lanthanum - pharmacology | Male | Neurons - cytology | Green Fluorescent Proteins - genetics | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Ion Channel Gating - physiology | Janus Kinase 2 - metabolism | Female | Appetite - physiology | Leptin - pharmacology | Neurons - metabolism | Neurons - drug effects | TRPC Cation Channels - genetics | Janus Kinase 2 - antagonists & inhibitors | Organ Culture Techniques | Membrane Potentials - drug effects | Boron Compounds - pharmacology | Phospholipase C gamma - metabolism | Appetite - drug effects | Mice, Transgenic | Imidazoles - pharmacology | Calcium Channel Blockers - pharmacology | Membrane Potentials - physiology | Pro-Opiomelanocortin - metabolism | Patch-Clamp Techniques | Animals | Hypothalamus - metabolism | Hypothalamus - cytology | Signal Transduction - drug effects | Calcium Signaling - drug effects | Staining and Labeling | TRPC Cation Channels - metabolism | Signal Transduction - physiology | Mice | Phospholipase C gamma - antagonists & inhibitors | Ion Channel Gating - drug effects | Brief Communications
Journal Article
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 01/2009, Volume 34, Issue 2, pp. 424 - 435
Pituitary adenylate cyclase-activating polypeptide ( PACAP) and the proopiomelanocortin (POMC)-derived peptide, alpha-melanocyte-stimulating hormone... 
POMC | Melanocortin | PAC1-R | PACAP | Food intake | Glucose homeostasis | PAC1 RECEPTOR | PSYCHIATRY | ARCUATE NUCLEUS | NEUROSCIENCES | ANOREXIGENIC ACTION | glucose homeostasis | BODY-WEIGHT | CORTICOTROPIN-RELEASING-FACTOR | HYPERPHAGIC RESPONSE | MESSENGER-RNA | VASOACTIVE INTESTINAL POLYPEPTIDE | FEEDING-BEHAVIOR | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | melanocortin | food intake | Pituitary Adenylate Cyclase-Activating Polypeptide - antagonists & inhibitors | Melanocyte-Stimulating Hormones - pharmacology | Receptor, Melanocortin, Type 3 - metabolism | Male | Peptide Fragments - pharmacology | Receptor, Melanocortin, Type 4 - metabolism | RNA, Messenger - metabolism | Eating - physiology | Dose-Response Relationship, Drug | Neuropeptide Y - metabolism | Vasoactive Intestinal Peptide - pharmacology | Arcuate Nucleus of Hypothalamus - drug effects | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Neurons - metabolism | Corticosterone - blood | Hypothalamus - drug effects | Neurons - drug effects | Pro-Opiomelanocortin - genetics | Receptor, Melanocortin, Type 4 - antagonists & inhibitors | Blood Glucose - analysis | Arcuate Nucleus of Hypothalamus - metabolism | Mice, Knockout | Pro-Opiomelanocortin - metabolism | Eating - drug effects | Animals | Hypothalamus - metabolism | Receptor, Melanocortin, Type 3 - antagonists & inhibitors | Mice | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics | Life Sciences | Neurons and Cognition
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 08/2016, Volume 311, Issue 2, pp. H433 - H444
Hypothalamic arcuate nucleus (ARCN) stimulation elicited increases in sympathetic nerve activity (IBATSNA) and temperature (T-BAT) of interscapular brown... 
Glutamate receptors | Bat nerve activity | Melanocortin receptors | Dorsomedial nucleus | Interscapular brown adipose tissue | Proopiomelanocortin | Paraventricular nucleus | Brown adipose tissue temperature | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | bat nerve activity | interscapular brown adipose tissue | RAT | brown adipose tissue temperature | RECEPTOR MESSENGER-RNA | BRAIN-STEM | SYSTEM REGULATION | PREOPTIC AREA | SYMPATHETIC OUTFLOW | NEUROPEPTIDE-Y | ARTERIAL-PRESSURE | FEEDING-BEHAVIOR | NEURONS | proopiomelanocortin | PERIPHERAL VASCULAR DISEASE | dorsomedial nucleus | melanocortin receptors | glutamate receptors | paraventricular nucleus | Immunohistochemistry | Muscimol - pharmacology | Paraventricular Hypothalamic Nucleus - physiology | Temperature | Neural Inhibition | Rats, Wistar | Sympathetic Nervous System - drug effects | 2-Amino-5-phosphonovalerate - pharmacology | Dorsomedial Hypothalamic Nucleus - physiology | Male | alpha-MSH - metabolism | N-Methylaspartate - pharmacology | Quinoxalines - pharmacology | Thermogenesis - physiology | Adipose Tissue, Brown - innervation | Sympathetic Nervous System - physiology | GABA-A Receptor Agonists - pharmacology | Arcuate Nucleus of Hypothalamus - drug effects | Dorsomedial Hypothalamic Nucleus - drug effects | Receptor, Melanocortin, Type 4 - antagonists & inhibitors | Microinjections | Rats | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Arcuate Nucleus of Hypothalamus - physiology | Vesicular Glutamate Transport Proteins - metabolism | Pro-Opiomelanocortin - metabolism | Paraventricular Hypothalamic Nucleus - drug effects | Animals | Receptor, Melanocortin, Type 3 - antagonists & inhibitors | Stilbamidines | 2-Amino-5-phosphonovalerate - analogs & derivatives | Adipose Tissue, Brown - drug effects | Glutamic Acid - metabolism | Thermogenesis - drug effects | Fluorescent Dyes | Physiological aspects | Nervous system, Sympathetic | Metabotropic glutamate receptors | Brown adipose tissue | Cardiovascular Neurohormonal Regulation
Journal Article