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Journal of Biological Chemistry, ISSN 0021-9258, 12/2005, Volume 280, Issue 52, pp. 42655 - 42668
How genetic and environmental factors interact in Parkinson disease is poorly understood. We have now compared the patterns of vulnerability and rescue of... 
OXIDATIVE DAMAGE | COMPLEX-I | MEMBRANE PERTURBATION | UBIQUITIN-PROTEIN LIGASE | DROSOPHILA MODEL | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODEL | C-ELEGANS | DEFICIENT MICE | HUNTINGTONS-DISEASE | TAUROURSODEOXYCHOLIC ACID | Oncogene Proteins - genetics | Cholagogues and Choleretics - pharmacology | Humans | Molecular Sequence Data | Immunoblotting | Pyridazines - pharmacology | Probucol - pharmacology | Taurochenodeoxycholic Acid - pharmacology | Copper - chemistry | Time Factors | Gene Deletion | Rotenone - pharmacology | Neurons - metabolism | alpha-Synuclein - genetics | Paraquat - pharmacology | Transgenes | Disease Models, Animal | Pyrazoles - pharmacology | Amino Acid Sequence | Parkinson Disease - pathology | Caenorhabditis elegans - metabolism | Electron Transport Complex I - antagonists & inhibitors | Gene Library | Animals, Genetically Modified | Iron - chemistry | Polyenes - pharmacology | Gene Expression Regulation | Oxygen Consumption | Intracellular Signaling Peptides and Proteins | Bile Acids and Salts - metabolism | Ions | Mitochondria - metabolism | Antioxidants - pharmacology | Genetic Techniques | Sequence Homology, Amino Acid | Protein Deglycase DJ-1 | Animals | Mutagenesis | Benzoates - pharmacology | Thiazoles - pharmacology | Mutation | 3-Hydroxybutyric Acid - pharmacology | Ubiquitin-Protein Ligases - genetics | Sodium Azide - pharmacology | Apoptosis | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2001, Volume 276, Issue 17, pp. 13750 - 13755
Journal Article
Journal Article
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 12/2014, Volume 1842, Issue 12, pp. 2517 - 2527
Journal Article
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 12/2016, Volume 1861, Issue 12, pp. 1968 - 1979
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 2010, Volume 323, Issue 2, pp. 246 - 255
The antioxidant and anti-inflammatory compound AGI-1067 (succinobucol) has potential as an oral anti-diabetic agent. AGI-1067 reduces H A1c, improves fasting... 
Oxidative stress | Beta-cell | Cytokines | Calcium | ER stress | Biphasic | Probucol | Inflammation | Glucose sensitivity | Antioxidant | Insulin | Succinobucol | Beta cells | KATP-channel | Glucokinase | Anti-inflammatory | channel | K | SIGNALING PATHWAYS | PHENOLIC ANTIOXIDANTS | ENDOPLASMIC-RETICULUM STRESS | CELL BIOLOGY | DIABETES-MELLITUS | SUCCINOBUCOL AGI-1067 | ENDOCRINOLOGY & METABOLISM | NITRIC-OXIDE | SELECTIVE-INHIBITION | PANCREATIC BETA-CELLS | K-ATP-channel | TRANSCRIPTION FACTOR | Islets of Langerhans - drug effects | Tolbutamide - pharmacology | Antihypertensive Agents - pharmacology | Diazoxide - pharmacology | Gene Expression - drug effects | Calcium - metabolism | Humans | Male | Potassium Channels - metabolism | Probucol - pharmacology | Probucol - analogs & derivatives | Islets of Langerhans - metabolism | Cell Death - drug effects | Insulin Secretion | Islets of Langerhans - physiology | Cytokines - metabolism | Anti-Inflammatory Agents - pharmacology | Mice, Inbred C57BL | Antioxidants - pharmacology | Hypoglycemic Agents - pharmacology | Insulin - metabolism | Animals | Glucose - metabolism | Keto Acids - pharmacology | Mice | Nitric Oxide Synthase Type II - metabolism | Index Medicus | calcium | insulin | anti-oxidant | biphasic | probucol | inflammation | beta-cell | anti-inflammatory | succinobucol | cytokines | oxidative stress | beta cells | glucose sensitivity | glucokinase
Journal Article
中国药理学报:英文版, ISSN 1671-4083, 2014, Volume 35, Issue 12, pp. 1556 - 1565
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2010, Volume 30, Issue 4, pp. 796 - 801
Journal Article
Cardiovascular Research, ISSN 0008-6363, 06/2010, Volume 86, Issue 3, pp. 526 - 534
In this study, we investigated the impact of enhancing cholesterol delivery to mitochondrial sterol 27-hydroxylase, via steroidogenic acute regulatory protein... 
ApoAI | Liver X receptor | Apolipoprotein | Sterol 27-hydroxylase | Atherosclerosis | Cholesterol efflux | ABCA1 | CARDIAC & CARDIOVASCULAR SYSTEMS | apoAI | TRANSPORTER A1 | LIPOID ADRENAL-HYPERPLASIA | BILE-ACID SYNTHESIS | FOAM CELLS | ATP-BINDING CASSETTE | STAR | STEROL 27-HYDROXYLASE CYP27A1 | DEGRADATION | EXPRESSION | Up-Regulation | Homeostasis | Hydrocarbons, Fluorinated - pharmacology | Immunoblotting | Cyclic CMP - analogs & derivatives | Orphan Nuclear Receptors - metabolism | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Probucol - pharmacology | Transfection | ATP-Binding Cassette Transporters - genetics | Biological Transport | Cyclic CMP - pharmacology | Liver X Receptors | ATP-Binding Cassette Transporters - metabolism | Lipid Metabolism - genetics | Lipoproteins, LDL - metabolism | ATP Binding Cassette Transporter 1 | Genes, Reporter | Cell Line | Orphan Nuclear Receptors - agonists | Cholestanetriol 26-Monooxygenase - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Gene Expression Regulation | Apolipoprotein A-I - metabolism | Phosphoproteins - genetics | Cholesterol - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Sulfonamides - pharmacology | Triglycerides - metabolism | Macrophages - metabolism | Animals | Cholestanetriol 26-Monooxygenase - metabolism | Hydroxycholesterols - metabolism | Macrophages - drug effects | Mice | Polyisoprenyl Phosphates - pharmacology | Mutation | ATP-Binding Cassette Transporters - antagonists & inhibitors | Index Medicus
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 3/2016, Volume 53, Issue 2, pp. 1280 - 1295
Journal Article