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Journal of Pharmaceutical Sciences, ISSN 0022-3549, 12/1974, Volume 63, Issue 12, pp. 1842 - 1848
Rats were treated chronically with increasing doses of trifluoperazine, prochlorperazine, fluphenazine, or perphenazine per os, and drug metabolites were... 
Phenothiazines (trifluoperazine fluphenazine, prochlorperazine, perphenazine)–isolation of drugs and metabolites in rat tissue, identification by mass spectrometry, synthesis | Trifluoperazine and metabolites–isolated from rat tissue, identified by mass spectrometry, synthesis | Piperazine-substituted phenothiazines–isolation and identification of rat tissue metabolites, ethylenediamine derivatives | Metabolism of phenothiazines–isolation and identification of drug and metabolites from rat tissue | Prochlorperazine and metabolites–isolated from rat tissue, identified by mass spectrometry, synthesis | Perphenazine and metabolites–isolated from rat tissue, identified by mass spectrometry, synthesis | Mass spectroscopy–identification, metabolites of trifluoperazine, fluphenazine, prochlorperazine, and perphenazine | Fluphenazine and metabolites– isolated from rat and dog tissues, identified by mass spectrometry, synthesis | Trifluoperazine and metabolites—isolated from rat tissue, identified by mass spectrometry, synthesis | Perphenazine and metabolites—isolated from rat tissue, identified by mass spectrometry, synthesis | Prochlorperazine and metabolites—isolated from rat tissue, identified by mass spectrometry, synthesis | Phenothiazines (trifluoperazine, fluphenazine, prochlorperazine, perphenazine)‐isolation of drugs and metabolites in rat tissue, identification by mass spectrometry, synthesis | Fluphenazine and metabolites—isolated from rat and dog tissues, identified by mass spectrometry, synthesis | Metabolism of phenothiazines—isolation and identification of drug and metabolites from rat tissue | Mass spectroscopy—identification, metabolites of trifluoperazine, fluphenazine, prochlorperazine, and perphenazine | Piperazine‐substituted phenothiazines—isolation and identification of rat tissue metabolites, ethylenediamine derivatives
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 06/1983, Volume 72, Issue 6, pp. 702 - 703
The propylpiperazine side chain of prochlorperazine was labeled with two, four, or six deuterium atoms by lithium aluminum deuteride reduction of the... 
Prochlorperazine—deuterium-labeled synthesis | Deuterium label—prochlorperazine synthesis | Prochlorperazine—deuterium‐labeled synthesis | Deuterium | Prochlorperazine | Isotope Labeling - methods
Journal Article
ONCOLOGY NURSING FORUM, ISSN 0190-535X, 05/2009, Volume 36, Issue 3, pp. 345 - 352
Purpose/Objectives: To synthesize the research to determine whether oral delta-9-tetrahycirocannabinol (THC) and smoked marijuana are effective treatments for... 
ONCOLOGY | PROCHLORPERAZINE | NURSING | RECEIVING CANCER-CHEMOTHERAPY | COMBINATION | CANNABINOIDS | DRONABINOL | Complications and side effects | Chemotherapy | Usage | Care and treatment | Marijuana | Nausea | Health aspects | Tetrahydrocannabinol | Risk factors | Cancer
Journal Article
Journal Article
Journal Article
Annals of Clinical Biochemistry, ISSN 0004-5632, 5/2018, Volume 55, Issue 3, pp. 385 - 393
Background Oral prochlorperazine, a dopamine D2 receptor antagonist, is largely metabolized to sulphoxide, 7-hydroxylate and N-desmethylate by cytochrome P450s... 
prolactin | cytochrome P450 | metabolites | Prochlorperazine | gene polymorphisms | antiemetic effect | OMEPRAZOLE | POLYMORPHISM | CHINESE POPULATION | MUTANT ALLELES | PHARMACOKINETICS | JAPANESE POPULATION | DOPAMINE | CYP2D6 GENE | MEDICAL LABORATORY TECHNOLOGY | EXPRESSION | DRUG-METABOLISM
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 7, p. e22274
Approximately half of estrogen receptor (ER) positive breast tumors will fail to respond to endocrine therapy. Here we used an integrative bioinformatics... 
APOPTOSIS | ANTIESTROGENS | CANCER CELLS | GENE | MOLECULE | MULTIDISCIPLINARY SCIENCES | CONNECTIVITY MAP | ESTROGEN | CARCINOMAS | INDUCTION | SIGNATURE | Biological Phenomena - genetics | Breast Neoplasms - classification | Small Molecule Libraries - pharmacology | Computational Biology - methods | Prochlorperazine - pharmacology | Oligonucleotide Array Sequence Analysis | Biological Phenomena - drug effects | Humans | Cyclins - genetics | Databases, Genetic | Gene Expression Profiling | E2F Transcription Factors - metabolism | Drug Resistance, Neoplasm - genetics | Breast Neoplasms - genetics | Cyclins - metabolism | Phenothiazines - pharmacology | Tamoxifen - pharmacology | Cell Line, Tumor | Female | Cell Proliferation - drug effects | Gene Expression Regulation, Neoplastic - drug effects | E2F Transcription Factors - genetics | Genes, Neoplasm - genetics | Drug Resistance, Neoplasm - drug effects | Analysis | Genes | Estrogen | Development and progression | Breast cancer | DNA binding proteins | Genetic transcription | Tamoxifen | Health aspects | Computational biology | Cell proliferation | Bioengineering | Transcription factors | Genomics | Estrogens | Estrogen receptors | Cytotoxicity | Autophagy | Cancer therapies | DNA repair | Datasets | Psychotropic drugs | E2F protein | Cell cycle | Physiology | Bioinformatics | Growth factors | Deoxyribonucleic acid--DNA | Integrated approach | Phenothiazines | Biophysics | Tumor cell lines | Gene expression | DNA microarrays | Medical prognosis | Data sets | Cell lines | Breast | Hypoxia | Tumors | Cancer | Apoptosis | Deoxyribonucleic acid | DNA
Journal Article
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