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1. Bone structural changes after gastric bypass surgery evaluated by HR-pQCT: A two-year longitudinal study
by Shanbhogue, Vikram V and Støving, René Klinkby and Frederiksen, Katrine Hartmund and Hanson, Stine and Brixen, Kim and Gram, Jeppe and Jørgensen, Niklas Rye and Hansen, Stinus
European journal of endocrinology, ISSN 0804-4643, 06/2017, Volume 176, Issue 6, pp. 685 - 693
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Postoperative Complications - etiology | Obesity, Morbid - surgery | Humans | Leptin - metabolism | Middle Aged | Postoperative Complications - metabolism | Male | Tomography, X-Ray Computed | Luteinizing Hormone - metabolism | Osteoporosis - etiology | Peptides - metabolism | Osteoporosis - metabolism | Parathyroid Hormone - metabolism | Osteoporosis - diagnostic imaging | Adiponectin - metabolism | Adult | Female | Follicle Stimulating Hormone - metabolism | Peptide Fragments - metabolism | Bone Density | Bone Diseases, Metabolic - diagnostic imaging | Collagen Type I - metabolism | Lumbar Vertebrae - diagnostic imaging | Bone Diseases, Metabolic - etiology | Tibia - diagnostic imaging | Gastric Bypass - adverse effects | Procollagen - metabolism | Absorptiometry, Photon | Bone Diseases, Metabolic - metabolism | Hip Joint - diagnostic imaging | Insulin - metabolism | Weight Loss | Vitamin D - analogs & derivatives | Vitamin D - metabolism | Bone Remodeling | Longitudinal Studies | Postoperative Complications - diagnostic imaging | Radius - diagnostic imaging | Dual energy X-ray absorptiometry | Radius | Spine | Body weight | Gastric bypass | Body weight loss | Bone turnover | Metabolism | Bone surgery | Insulin | Hip | Osteoporosis | Bone mass | Fractures | Computed tomography | Tibia | Leptin | Bone mineral density | Gastrointestinal surgery | Bone loss | Bone strength
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2. Full Text Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
by Xu, Wei and Yang, Hui and Liu, Ying and Yang, Ying and Wang, Ping and Kim, Se-Hee and Ito, Shinsuke and Yang, Chen and Wang, Pu and Xiao, Meng-Tao and Liu, Li-xia and Jiang, Wen-qing and Liu, Jing and Zhang, Jin-ye and Wang, Bin and Frye, Stephen and Zhang, Yi and Xu, Yan-hui and Lei, Qun-ying and Guan, Kun-Liang and Zhao, Shi-min and Xiong, Yue
Cancer cell, ISSN 1535-6108, 2011, Volume 19, Issue 1, pp. 17 - 30
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Dioxygenases - metabolism | Histone Demethylases - antagonists & inhibitors | Gene Expression - genetics | Caenorhabditis elegans Proteins - chemistry | Humans | Ketoglutaric Acids - chemistry | Glioma - genetics | F-Box Proteins | Oxidoreductases, N-Demethylating - antagonists & inhibitors | Ketoglutaric Acids - pharmacology | Cytosine - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Glutarates - chemistry | Oxidoreductases, N-Demethylating - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Glioma - enzymology | Endostatins - metabolism | Models, Molecular | Isocitrate Dehydrogenase - genetics | Histone Demethylases - metabolism | Dioxygenases - antagonists & inhibitors | Amino Acid Substitution - physiology | Procollagen-Proline Dioxygenase - genetics | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Glutarates - pharmacology | Histones - metabolism | Jumonji Domain-Containing Histone Demethylases - metabolism | Caenorhabditis elegans - enzymology | Cytosine - analogs & derivatives | Gene Expression - drug effects | Caenorhabditis elegans Proteins - metabolism | Isocitrate Dehydrogenase - antagonists & inhibitors | Glioma - metabolism | Procollagen-Proline Dioxygenase - metabolism | DNA-Binding Proteins - metabolism | Mixed Function Oxygenases | Biocatalysis - drug effects | Jumonji Domain-Containing Histone Demethylases - antagonists & inhibitors | Jumonji Domain-Containing Histone Demethylases - chemistry | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Ketoglutaric Acids - metabolism | Oxalates - pharmacology | Binding, Competitive | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Catalytic Domain | Proto-Oncogene Proteins - genetics | Hypoxia-Inducible Factor-Proline Dioxygenases | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Animals | 5-Methylcytosine - metabolism | Caenorhabditis elegans Proteins - antagonists & inhibitors | Glutarates - metabolism | Index Medicus
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3. Full Text Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism
by De Bock, Katrien and Moons, Lieve and Lafuste, Peggy and Tjwa, Marc and Gnaiger, Erich and Fraisl, Peter and Pugh, Chris and Deroose, Christophe and Grosfeld, Alexandra and Wijeyekoon, Bhathiya and Harten, Sarah K and Van Noten, Pieter and Carmeliet, Peter and Van Hecke, Paul and Vandendriessche, Thierry and Aragonés, Julián and Silasi-Mansat, Robert and Dewerchin, Mieke and Schneider, Martin and Mortelmans, Luc and Buyse, Johan and Diez-Juan, Antonio and Willam, Carsten and Maxwell, Patrick and Van Geyte, Katie and Gorus, Frans and Zacchigna, Serena and Dirkx, Ruud and Nuyts, Johan and Jordan, Benedicte and Salmon, Phil and Harris, Robert A and Lemieux, Hélène and Van Veldhoven, Paul and Bishop, Tammie and Ratcliffe, Peter and Jeoung, Nam Ho and Baes, Myriam and Hespel, Peter and Schuit, Frans and Lupu, Florea and Dresselaers, Tom and Mazzone, Massimiliano and Lambrechts, Diether and Gallez, Bernard and Sluse, Francis and Navet, Rachel
Nature genetics, ISSN 1061-4036, 02/2008, Volume 40, Issue 2, pp. 170 - 180
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Immunohistochemistry | Embryo, Mammalian | Glutamates - metabolism | Muscle, Skeletal - metabolism | Tomography, X-Ray Computed | Mitochondria - ultrastructure | Oxygen Consumption - physiology | Hypoxia - metabolism | Nuclear Magnetic Resonance, Biomolecular | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Basal Metabolism | Energy Metabolism - genetics | Energy Metabolism - physiology | Fibroblasts - metabolism | Carbon Dioxide - metabolism | Oxidation-Reduction | Mitochondria - metabolism | Carbon Isotopes - metabolism | Homozygote | Animals | Procollagen-Proline Dioxygenase - deficiency | Procollagen-Proline Dioxygenase - genetics | Models, Biological | Oxygen Consumption - genetics | Glucose - metabolism | Carbon Radioisotopes - metabolism | Mice | Physiological aspects | Glucose metabolism | Hypoxia | Research | Hydroxylases | Genetics | Oxygen | Metabolism | Index Medicus
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4. Full Text Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF-kappa B/IL-8 Pathway that Drives Tumor Angiogenesis
by Vegran, Frederique and Boidot, Romain and Michiels, Carine and Sonveaux, Pierre and Feron, Olivier
Cancer research (Chicago, Ill.), ISSN 0008-5472, 04/2011, Volume 71, Issue 7, pp. 2550 - 2560
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Tumors | Reactive Oxygen Species - metabolism | Humans | Cell Growth Processes - physiology | NF-kappa B - metabolism | I-kappa B Proteins - metabolism | Breast Neoplasms - metabolism | Procollagen-Proline Dioxygenase - metabolism | Lactic Acid - pharmacokinetics | Monocarboxylic Acid Transporters - metabolism | Ketoglutaric Acids - pharmacology | Muscle Proteins - metabolism | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Interleukin-8 - metabolism | Ketoglutaric Acids - metabolism | Lactic Acid - pharmacology | Colorectal Neoplasms - metabolism | Colorectal Neoplasms - blood supply | Signal Transduction | Interleukin-8 - biosynthesis | Hypoxia-Inducible Factor-Proline Dioxygenases | Breast Neoplasms - blood supply | Symporters - metabolism | Breast Neoplasms - pathology | Cell Line, Tumor | Neovascularization, Pathologic - metabolism | Colorectal Neoplasms - pathology | Index Medicus
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5. Full Text An association between abnormal bone turnover, systemic inflammation, and osteoporosis in patients with chronic pancreatitis: A case-matched study
by Duggan, Sinead N and Purcell, Christina and Kilbane, Mark and O'Keane, Myra and McKenna, Malachi and Gaffney, Peter and Ridgway, Paul F and Boran, Gerard and Conlon, Kevin C
The American journal of gastroenterology, ISSN 0002-9270, 02/2015, Volume 110, Issue 2, pp. 336 - 345
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Prospective Studies | Humans | Middle Aged | Male | Case-Control Studies | Femur Neck - diagnostic imaging | Inflammation - metabolism | C-Reactive Protein - metabolism | Osteoporosis - metabolism | Bone Diseases, Metabolic - complications | Parathyroid Hormone - metabolism | Bone and Bones - metabolism | Osteoporosis - diagnostic imaging | Bone Resorption - metabolism | Adult | Female | Interleukin-6 - metabolism | Gonadal Steroid Hormones - metabolism | Peptide Fragments - metabolism | Bone Density | Bone Diseases, Metabolic - diagnostic imaging | Collagen Type I - metabolism | Lumbar Vertebrae - diagnostic imaging | Osteocalcin - metabolism | Procollagen - metabolism | Absorptiometry, Photon | Bone Diseases, Metabolic - metabolism | Pancreatitis, Chronic - complications | Thyroid Hormones - metabolism | Osteoporosis - complications | Vitamin D - analogs & derivatives | Vitamin D - metabolism | Pancreatitis, Chronic - metabolism | Osteogenesis | Smoking | Index Medicus
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6. Full Text Insulin Resistance Is Associated With Smaller Cortical Bone Size in Nondiabetic Men at the Age of Peak Bone Mass
by Verroken, Charlotte and Zmierczak, Hans-Georg and Goemaere, Stefan and Kaufman, Jean-Marc and Lapauw, Bruno
The journal of clinical endocrinology and metabolism, ISSN 0021-972X, 06/2017, Volume 102, Issue 6, pp. 1807 - 1815
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Body Composition | Radius - pathology | Humans | Leptin - metabolism | Middle Aged | Male | Tomography, X-Ray Computed | Cortical Bone - pathology | Tibia - pathology | Tandem Mass Spectrometry | Testosterone - metabolism | Peptides - metabolism | Parathyroid Hormone - metabolism | Chromatography, Liquid | Adiponectin - metabolism | Adult | Muscle Strength | Estradiol - metabolism | Peptide Fragments - metabolism | Bone Density | Collagen Type I - metabolism | Osteocalcin - metabolism | Insulin Resistance | Tibia - diagnostic imaging | Organ Size | Sex Hormone-Binding Globulin - metabolism | Procollagen - metabolism | Absorptiometry, Photon | Insulin - metabolism | Muscle, Skeletal - diagnostic imaging | Vitamin D - analogs & derivatives | Vitamin D - metabolism | Muscle, Skeletal - pathology | Blood Glucose - metabolism | Cortical Bone - diagnostic imaging | Insulin-Like Growth Factor I - metabolism | Radius - diagnostic imaging | Serum Albumin - metabolism | Radius | Sex | Homeostasis | Population studies | Bone (trabecular) | Body composition | Adiponectin | Computed tomography | Body composition (biology) | Bone (cortical) | Age | Bone composition | Dual energy X-ray absorptiometry | Diabetes mellitus | Health risks | Muscles | Excavation | Bone turnover | Insulin | Geometry | Bone mass | Leptin | Body size | Men | Insulin resistance | Bone mineral density | Index Medicus | Abridged Index Medicus
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7. Full Text Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
by Kaelin, William G and Ratcliffe, Peter J
Molecular cell, ISSN 1097-2765, 05/2008, Volume 30, Issue 4, pp. 393 - 402
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Reactive Oxygen Species - metabolism | Isoenzymes - genetics | Humans | Enzyme Stability | Gene Expression Regulation | Repressor Proteins - genetics | Transcription Factors - genetics | Hypoxia-Inducible Factor 1 - metabolism | Iron - metabolism | Oxygen - metabolism | Ascorbic Acid - metabolism | Citric Acid Cycle | Hypoxia-Inducible Factor 1 - genetics | Procollagen-Proline Dioxygenase - metabolism | Mixed Function Oxygenases | Transcription Factors - metabolism | Animals | Procollagen-Proline Dioxygenase - genetics | Isoenzymes - metabolism | Asparagine - metabolism | Signal Transduction - physiology | Transcription, Genetic | Nitric Oxide - metabolism | Repressor Proteins - metabolism | Physiological aspects | Hydroxylases | Metabolites | Hydroxylation | Nitric oxide | Index Medicus
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8. Full Text High fat diet feeding results in gender specific steatohepatitis and inflammasome activation
by Michal Ganz Timea Csak Gyongyi Szabo
World journal of gastroenterology : WJG, ISSN 1007-9327, 2014, Volume 20, Issue 26, pp. 8525 - 8534
steatohepatitis | Gender | Non-alcoholic | differences | Gender differences | Inflammasome | Non-alcoholic steatohepatitis | High fat diet | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Non-alcoholic Fatty Liver Disease - pathology | Liver - pathology | Inflammasomes - metabolism | Actins - metabolism | Diet, High-Fat - adverse effects | Non-alcoholic Fatty Liver Disease - etiology | Caspase 1 - metabolism | Male | Alanine Transaminase - blood | Insulin - blood | RNA, Messenger - metabolism | Actins - genetics | DNA-Binding Proteins - metabolism | Liver - immunology | Collagen Type I - genetics | Time Factors | Interleukin-1beta - metabolism | Inflammation Mediators - metabolism | Liver Cirrhosis - metabolism | Female | Chemokine CCL2 - metabolism | Weight Gain | Liver Cirrhosis - etiology | Procollagen - genetics | Collagen Type I - metabolism | Fructose - adverse effects | Non-alcoholic Fatty Liver Disease - genetics | Liver - metabolism | Mice, Inbred C57BL | Non-alcoholic Fatty Liver Disease - immunology | Insulin Resistance | Chemokine CCL2 - genetics | Non-alcoholic Fatty Liver Disease - metabolism | Procollagen - metabolism | DNA-Binding Proteins - genetics | Inflammasomes - genetics | Animals | Inflammasomes - immunology | Sex Factors | Triglycerides - blood | Liver Cirrhosis - pathology | Dietary Sucrose - adverse effects | Blood Glucose - metabolism | Index Medicus | Original
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9. Full Text O-Glycosylated Cell Wall Proteins Are Essential in Root Hair Growth
by Silvia M. Velasquez and Martiniano M. Ricardi and Javier Gloazzo Dorosz and Paula V. Fernandez and Alejandro D. Nadra and Laercio Pol-Fachin and Jack Egelund and Sascha Gille and Jesper Harholt and Marina Ciancia and Hugo Verli and Markus Pauly and Antony Bacic and Carl Erik Olsen and Peter Ulvskov and Bent Larsen Petersen and Chris Somerville and Norberto D. Iusem and Jose M. Estevez
Science (American Association for the Advancement of Science), ISSN 0036-8075, 6/2011, Volume 332, Issue 6036, pp. 1401 - 1403
Enzymes | Cell growth | Phenotypes | Polysaccharides | Cell walls | RESEARCH ARTICLES | Hair cells | Root hairs | Biochemistry | Plants | Plant cells | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Plant physiology and development | Arabidopsis - growth & development | Genes, Plant | Proline - metabolism | Glycoproteins - metabolism | Pentosyltransferases - metabolism | Procollagen-Proline Dioxygenase - metabolism | Arabidopsis Proteins - metabolism |