X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (1680) 1680
procollagen-proline dioxygenase - metabolism (1226) 1226
animals (1116) 1116
humans (886) 886
male (437) 437
procollagen-proline dioxygenase - genetics (413) 413
biochemistry & molecular biology (366) 366
rats (352) 352
mice (343) 343
hypoxia (305) 305
collagen - biosynthesis (300) 300
procollagen-proline dioxygenase - antagonists & inhibitors (295) 295
female (288) 288
hypoxia-inducible factor 1, alpha subunit - metabolism (269) 269
cell biology (247) 247
cells, cultured (236) 236
hydroxylation (233) 233
hypoxia-inducible factor-proline dioxygenases (232) 232
collagen - metabolism (209) 209
collagen (193) 193
cell line (182) 182
hypoxia-inducible factor (178) 178
expression (177) 177
oxygen - metabolism (165) 165
prolyl hydroxylase (153) 153
hif-1-alpha (136) 136
kinetics (131) 131
rna, messenger - metabolism (127) 127
hydroxylases (126) 126
hydroxyproline - metabolism (126) 126
amino acid sequence (124) 124
chick embryo (124) 124
time factors (124) 124
molecular sequence data (123) 123
gene expression (122) 122
procollagen-proline dioxygenase - chemistry (122) 122
proline - metabolism (122) 122
hypoxia-inducible factor 1, alpha subunit - genetics (121) 121
oxygen (121) 121
proteins (117) 117
gene-expression (112) 112
adult (110) 110
hif (110) 110
hif-alpha (109) 109
cell line, tumor (108) 108
prolyl 4-hydroxylase (108) 108
enzymes (106) 106
enzyme inhibitors - pharmacology (105) 105
signal transduction (102) 102
abridged index medicus (101) 101
protein (101) 101
fibroblasts - metabolism (100) 100
middle aged (100) 100
research (99) 99
protein binding (97) 97
cells (96) 96
transcription factors - metabolism (96) 96
cancer (91) 91
oncology (90) 90
article (88) 88
gene expression regulation (88) 88
hypoxia-inducible factor 1, alpha subunit (88) 88
angiogenesis (86) 86
physiological aspects (85) 85
cell hypoxia (84) 84
disease models, animal (84) 84
rna, messenger - genetics (82) 82
hypoxia-inducible factor 1 - metabolism (79) 79
immunohistochemistry (79) 79
hypoxia - metabolism (75) 75
procollagen-proline dioxygenase (74) 74
procollagen-proline dioxygenase - physiology (73) 73
apoptosis (71) 71
liver - metabolism (71) 71
activation (70) 70
inhibition (70) 70
mice, inbred c57bl (69) 69
mutation (69) 69
factor-i (68) 68
blotting, western (67) 67
procollagen-proline dioxygenase - biosynthesis (67) 67
dna-binding proteins - metabolism (66) 66
hydroxylase (66) 66
multidisciplinary sciences (66) 66
physiology (66) 66
mice, knockout (65) 65
basic helix-loop-helix transcription factors - metabolism (64) 64
endothelial growth-factor (64) 64
liver - enzymology (64) 64
aged (63) 63
ascorbic acid - pharmacology (63) 63
family (63) 63
nuclear proteins - metabolism (63) 63
procollagen-proline dioxygenase - analysis (62) 62
proline hydroxylation (62) 62
rats, sprague-dawley (62) 62
binding sites (60) 60
procollagen-lysine, 2-oxoglutarate 5-dioxygenase - metabolism (60) 60
protein structure, tertiary (59) 59
analysis (58) 58
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1654) 1654
Japanese (17) 17
German (15) 15
French (14) 14
Chinese (11) 11
Polish (4) 4
Russian (4) 4
Spanish (2) 2
Czech (1) 1
Italian (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cancer Cell, ISSN 1535-6108, 2011, Volume 19, Issue 1, pp. 17 - 30
and mutations occur frequently in gliomas and acute myeloid leukemia, leading to simultaneous loss and gain of activities in the production of α-ketoglutarate... 
BREAST-CANCER | TRANSCRIPTIONAL ACTIVITY | IDH2 MUTATIONS | ONCOLOGY | PROLYL HYDROXYLATION | INTEGRATED GENOMIC ANALYSIS | 2-OXOGLUTARATE OXYGENASES | ACUTE MYELOID-LEUKEMIA | HIF-ALPHA | HISTONE DEMETHYLATION | FAMILY | CELL BIOLOGY | Dioxygenases - metabolism | Histone Demethylases - antagonists & inhibitors | Gene Expression - genetics | Caenorhabditis elegans Proteins - chemistry | Humans | Ketoglutaric Acids - chemistry | Glioma - genetics | F-Box Proteins | Oxidoreductases, N-Demethylating - antagonists & inhibitors | Ketoglutaric Acids - pharmacology | Cytosine - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Glutarates - chemistry | Oxidoreductases, N-Demethylating - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Glioma - enzymology | Endostatins - metabolism | Models, Molecular | Isocitrate Dehydrogenase - genetics | Histone Demethylases - metabolism | Dioxygenases - antagonists & inhibitors | Amino Acid Substitution - physiology | Procollagen-Proline Dioxygenase - genetics | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Glutarates - pharmacology | Histones - metabolism | Jumonji Domain-Containing Histone Demethylases - metabolism | Caenorhabditis elegans - enzymology | Cytosine - analogs & derivatives | Gene Expression - drug effects | Caenorhabditis elegans Proteins - metabolism | Isocitrate Dehydrogenase - antagonists & inhibitors | Glioma - metabolism | Procollagen-Proline Dioxygenase - metabolism | DNA-Binding Proteins - metabolism | Mixed Function Oxygenases | Biocatalysis - drug effects | Jumonji Domain-Containing Histone Demethylases - antagonists & inhibitors | Jumonji Domain-Containing Histone Demethylases - chemistry | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Ketoglutaric Acids - metabolism | Oxalates - pharmacology | Binding, Competitive | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Catalytic Domain | Proto-Oncogene Proteins - genetics | Hypoxia-Inducible Factor-Proline Dioxygenases | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Animals | 5-Methylcytosine - metabolism | Caenorhabditis elegans Proteins - antagonists & inhibitors | Glutarates - metabolism | Index Medicus
Journal Article
Journal Article
Nature, ISSN 0028-0836, 03/2012, Volume 483, Issue 7390, pp. 484 - 488
Journal Article
Cell, ISSN 0092-8674, 2001, Volume 107, Issue 1, pp. 43 - 54
HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. Recent studies have defined posttranslational modification by... 
UBIQUITINATION | SYNTHASE | CAENORHABDITIS-ELEGANS | GENE | MECHANISM | INDUCIBLE FACTOR 1-ALPHA | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-SUPPRESSOR PROTEIN | HYPOXIA | EXPRESSION | BINDING | CELL BIOLOGY | Humans | Helminth Proteins - chemistry | Homeostasis | Molecular Sequence Data | Chromatography, High Pressure Liquid | Hypoxia-Inducible Factor 1, alpha Subunit | Oxygen - metabolism | Procollagen-Proline Dioxygenase - metabolism | DNA-Binding Proteins - metabolism | Caenorhabditis elegans - physiology | 2,2'-Dipyridyl - metabolism | Nuclear Proteins - genetics | Helminth Proteins - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | Caenorhabditis elegans Proteins | Hydroxylation | Hypoxia-Inducible Factor 1 | Protein Structure, Secondary | Gene Expression Regulation - genetics | Ligases - metabolism | Rats | Nuclear Proteins - metabolism | Helminth Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Transcription Factors - metabolism | Ubiquitin-Protein Ligases | Sequence Alignment | Animals | Protein Isoforms | Indicators and Reagents | Von Hippel-Lindau Tumor Suppressor Protein | HeLa Cells | Tumor Suppressor Proteins | Enzymes | Oxygen | Physiological aspects | Regulation | Physiological transport | Genetic regulation | dioxygenase | EGL-9 protein | HIF complex | prolyl hydroxylase | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 11/2011, Volume 479, Issue 7371, pp. 122 - 126
Journal Article
Journal Article
Cancer Cell, ISSN 1535-6108, 10/2011, Volume 20, Issue 4, pp. 524 - 537
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2007, Volume 282, Issue 7, pp. 4524 - 4532
The stability and transcriptional activity of the hypoxia-inducible factors (HIFs) are regulated by two oxygen-dependent events that are catalyzed by three HIF... 
Gene Expression Regulation, Enzymologic - drug effects | Transcription, Genetic - drug effects | Vascular Endothelial Growth Factor A - biosynthesis | Fibroblasts - enzymology | Fumarate Hydratase - chemistry | Mixed Function Oxygenases - metabolism | Fumarate Hydratase - deficiency | Mixed Function Oxygenases - chemistry | Succinate Dehydrogenase - chemistry | Procollagen-Proline Dioxygenase - metabolism | Dose-Response Relationship, Drug | Fumarate Hydratase - metabolism | Neoplasms - chemistry | Neoplasms - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Hypoxia-Inducible Factor 1, alpha Subunit - chemistry | Erythropoietin - biosynthesis | Fibroblasts - chemistry | Cell Line | Enzyme Inhibitors - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Citric Acid Cycle - drug effects | Neoplasms - enzymology | Mixed Function Oxygenases - antagonists & inhibitors | Fibroblasts - pathology | Succinate Dehydrogenase - deficiency | p300-CBP Transcription Factors - metabolism | Citric Acid Cycle - genetics | Procollagen-Proline Dioxygenase - genetics | Gene Expression Regulation, Enzymologic - genetics | Succinate Dehydrogenase - metabolism | Mixed Function Oxygenases - genetics | Neoplasms - pathology | Procollagen-Proline Dioxygenase - chemistry | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 2005, Volume 7, Issue 1, pp. 77 - 85
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2012, Volume 122, Issue 12, pp. 4635 - 4644
Iron demand in bone marrow increases when erythropoiesis is stimulated by hypoxia via increased erythropoietin (EPO) synthesis in kidney and liver. Hepcidin, a... 
PEPTIDE HEPCIDIN | MEDICINE, RESEARCH & EXPERIMENTAL | DIFFERENTIATION FACTOR 15 | IRON HOMEOSTASIS | INEFFECTIVE ERYTHROPOIESIS | DOWN-REGULATION | CHUVASH POLYCYTHEMIA | MICE | ANEMIA | BETA-THALASSEMIA | EXPRESSION | Erythropoiesis | Humans | Hepatocytes - metabolism | Antimicrobial Cationic Peptides - metabolism | Procollagen-Proline Dioxygenase - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Hepcidins | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Antimicrobial Cationic Peptides - genetics | Von Hippel-Lindau Tumor Suppressor Protein - metabolism | Gene Expression | Basic Helix-Loop-Helix Transcription Factors - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Liver - metabolism | Gene Expression Regulation | Hypoxia-Inducible Factor-Proline Dioxygenases | Erythropoietin - physiology | Mice, Knockout | Animals | Growth Differentiation Factor 15 - blood | Procollagen-Proline Dioxygenase - genetics | Cell Line, Tumor | Liver - cytology | Mice | Erythropoietin | Physiological aspects | Hypoxia | Research | Properties | Biological control systems | Index Medicus | Abridged Index Medicus | Adaptations | Hypoxia-inducible factors | Liver | Iron | Kidney | Serum levels | Hepatocytes | Intestine | Bone marrow | Differentiation | Hepcidin
Journal Article
Journal Article
Science, ISSN 0036-8075, 6/2011, Volume 332, Issue 6036, pp. 1401 - 1403
Root hairs are single cells that develop by tip growth and are specialized in the absorption of nutrients. Their cell walls are composed of polysaccharides and... 
Enzymes | Cell growth | Phenotypes | Polysaccharides | Cell walls | RESEARCH ARTICLES | Hair cells | Root hairs | Biochemistry | Plants | Plant cells | MOLECULAR CHARACTERIZATION | MUTANTS | EXTENSIN | CODES | MULTIDISCIPLINARY SCIENCES | GENES | REQUIRES | ARABIDOPSIS | IDENTIFICATION | PROLYL 4-HYDROXYLASE | TOBACCO | Arabidopsis - growth & development | Genes, Plant | Proline - metabolism | Glycoproteins - metabolism | Pentosyltransferases - metabolism | Procollagen-Proline Dioxygenase - metabolism | Arabidopsis Proteins - metabolism | Pentosyltransferases - chemistry | Plant Proteins - chemistry | Arabinose - metabolism | Gene Expression Regulation, Plant | Polysaccharides - chemistry | Plant Proteins - metabolism | Glycosyltransferases - genetics | Glycoproteins - chemistry | Plant Roots - growth & development | Arabidopsis Proteins - genetics | Plant Roots - metabolism | Hydroxylation | Protein Structure, Secondary | Hydroxyproline - metabolism | Glycosylation | Plant Roots - cytology | Arabidopsis - metabolism | Arabidopsis - genetics | Glycosyltransferases - metabolism | Phenotype | Arabidopsis Proteins - chemistry | Procollagen-Proline Dioxygenase - genetics | Models, Biological | Cell Wall - metabolism | Protein Conformation | Protein Processing, Post-Translational | Mutation | Carbohydrate Conformation | Hair | Physiological aspects | Glycoproteins | Genetic aspects | Growth | Self assembly | Roots | Genetics | Elongation | Walls | Blockage | Index Medicus
Journal Article