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Nature, ISSN 0028-0836, 04/2011, Volume 472, Issue 7342, pp. 221 - 227
Journal Article
by Xu, SW and Jin, ZG
TRENDS IN BIOCHEMICAL SCIENCES, ISSN 0968-0004, 07/2019, Volume 44, Issue 7, pp. 561 - 564
Hutchinson-Gilford progeria syndrome (HGPS) is an ultrarare and fatal disease with features of premature aging and cardiovascular diseases (atherosclerosis,... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | Progeria | Heart attack | Atherosclerosis | Myocardial infarction | Cerebral infarction | Stroke | Genetic disorders | Medical treatment | Cardiovascular disease | Pathology | Arteriosclerosis | Aging | Cardiovascular diseases | Heart diseases
Journal Article
Nature Communications, ISSN 2041-1723, 2015, Volume 6, Issue 1, pp. 6494 - 6494
Journal Article
Nature Genetics, ISSN 1061-4036, 08/2009, Volume 41, Issue 8, pp. 891 - 898
Although DNA damage is considered a driving force for aging, the nature of the damage that arises endogenously remains unclear. Replicative stress, a source of... 
CHROMOSOME INSTABILITY | GENE ATR | DNA-DAMAGE RESPONSE | HEMATOPOIETIC STEM-CELLS | GENETICS & HEREDITY | LEADS | CHECKPOINT | DEFICIENT MICE | ATAXIA-TELANGIECTASIA | AGE | P53 | Abnormalities, Multiple - pathology | Embryo, Mammalian - drug effects | Protein-Serine-Threonine Kinases - deficiency | Fibroblasts - enzymology | Apoptosis - drug effects | DNA Replication - drug effects | Humans | Aging - drug effects | Brain - enzymology | Embryo, Mammalian - metabolism | DNA-Binding Proteins - metabolism | Aging - genetics | Progeria - embryology | DNA-Activated Protein Kinase - metabolism | Progeria - pathology | Embryo, Mammalian - enzymology | Stress, Physiological - drug effects | Abnormalities, Multiple - genetics | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | DNA Repair - drug effects | Embryo, Mammalian - pathology | Progeria - enzymology | Cell Cycle Proteins - metabolism | Tumor Suppressor Protein p53 - metabolism | Nuclear Proteins - metabolism | Ataxia Telangiectasia Mutated Proteins | Fibroblasts - pathology | Tumor Suppressor Protein p53 - deficiency | Syndrome | Aging - pathology | Phenotype | Animals | Fibroblasts - drug effects | Alleles | Abnormalities, Multiple - enzymology | Brain - pathology | Mice | Protein Kinase Inhibitors - pharmacology | DNA Damage | Embryonic development | Usage | Control | Animal models in research | DNA damage | Causes of | Physiological aspects | Genetic aspects | Research | Proteins | Dwarfism | Studies | Genotype & phenotype | Cell cycle | Kinases | Molecular biology | Cancer | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, pp. 5744 - 5744
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2014, Volume 35, Issue 9, pp. 2147 - 2160
Journal Article
Human molecular genetics, ISSN 0964-6906, 2004, Volume 13, Issue 20, pp. 2493 - 2503
Journal Article
Aging Cell, ISSN 1474-9718, 02/2019, Volume 18, Issue 1, pp. e12852 - n/a
Hutchinson‐Gilford Progeria Syndrome (HGPS) is a devastating premature aging disease. Mouse models have been instrumental for understanding HGPS mechanisms and... 
CANCER CACHEXIA | KAPPA-B ACTIVATION | FARNESYLTRANSFERASE INHIBITOR | DEFECTS | ACID | MOUSE MODEL | DISEASE | SATELLITE CELLS | STARVATION | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | Medicine, Experimental | Medical research | Starvation | Progeria | Analysis | Atherosclerosis | Animal models | Phenotypes | Life span | Etiology | Arteriosclerosis | Aging | Lethality | Cachexia | Morbidity | High fat diet | Original Paper | Original Papers
Journal Article