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Biochemical Journal, ISSN 0264-6021, 07/2011, Volume 437, Issue 1, pp. 53 - 61
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 14796 - 13
The short chain dehydrogenase/reductase superfamily (SDR) is a large family of NAD(P) H-dependent enzymes found in all kingdoms of life. SDRs are particularly... 
ROSEUS | REFINEMENT | PROTEIN | PATHWAY | 7-DEOXYLOGANETIC ACID | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | PROGESTERONE 5-BETA-REDUCTASE | STEP | IRIDOID SYNTHASE | Medicinal plants | NADPH | Enzymes | Enzymatic activity | Mutagenesis | Substrate specificity | Site-directed mutagenesis | Progesterone | Citral | Reductase | Structure-function relationships | Life Sciences
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 10/2017, Volume 276, pp. 167 - 173
Carbonyl reduction is an important metabolic pathway for endogenous and xenobiotic substances. The tobacco specific nitrosamine... 
Enzyme inhibition | Sex hormones | 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) | Short-chain dehydrogenases/reductases (SDR) | Carbonyl reduction | Aldo-keto reductases (AKR) | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-HYDROXYSTEROID DEHYDROGENASE | CARCINOGEN NNK | 4-METHYLNITROSAMINO-1-(3-PYRIDYL)-1-BUTANONE NNK | CIGARETTE-SMOKING | PHARMACOLOGY & PHARMACY | HUMAN LIVER | F344 RATS | TOXICOLOGY | LUNG-CANCER RISK | TOBACCO-SPECIFIC NITROSAMINE | N-NITROSAMINES | Inactivation, Metabolic | Aldo-Keto Reductases - genetics | Liver - enzymology | Nitrosamines - metabolism | Humans | Gonadal Hormones - chemistry | Recombinant Proteins - biosynthesis | Carcinogens - metabolism | Recombinant Proteins - isolation & purification | Progesterone - chemistry | Short Chain Dehydrogenase-Reductases - antagonists & inhibitors | Carcinogens - chemistry | Aldo-Keto Reductases - antagonists & inhibitors | Estradiol - metabolism | Tobacco - metabolism | Nitrosamines - chemistry | Recombinant Proteins - chemistry | Short Chain Dehydrogenase-Reductases - genetics | Gonadal Hormones - metabolism | Androstenes - chemistry | Estradiol - chemistry | Aldo-Keto Reductases - metabolism | Progesterone - metabolism | Androstenes - metabolism | Tobacco - chemistry | Short Chain Dehydrogenase-Reductases - metabolism | Testosterone | Enzymes | Analysis | Lung cancer | Physiological aspects | Development and progression | Ethinyl estradiol | Progesterone | Hormones | Oral contraceptives | Nitrosoamines | Estradiol | Index Medicus
Journal Article
Journal Article
Journal Article
Animal Science Journal, ISSN 1344-3941, 11/2018, Volume 89, Issue 11, pp. 1540 - 1548
The spleen is a unique lymphoid organ that plays a key role in immune regulation. Interferon‐tau induces upregulation of interferon‐stimulated gene 15‐kDa... 
prostaglandin synthase | ISG15 | spleen | sheep | pregnancy | CELLS | AGRICULTURE, DAIRY & ANIMAL SCIENCE | PROGESTERONE | UTERUS | BONE-MARROW | TAU | RECEPTOR | MECHANISMS | MATERNAL RECOGNITION | IDENTIFICATION | Up-Regulation | Aldehyde Reductase - genetics | Spleen - immunology | Ubiquitins - genetics | Uterus - metabolism | Pregnancy, Animal - genetics | Cyclooxygenase 2 - genetics | Prostaglandin-E Synthases - genetics | Pregnancy, Animal - immunology | Aldehyde Reductase - metabolism | Female | Placentation - genetics | Sheep - genetics | Cytokines - genetics | Ubiquitins - metabolism | Cyclooxygenase 1 - genetics | Gene Expression | Cytokines - metabolism | Prostaglandin-E Synthases - metabolism | Placentation - physiology | Pregnancy | Animals | Spleen - metabolism | Cyclooxygenase 2 - metabolism | Sheep - metabolism | Cyclooxygenase 1 - metabolism | COX-2 inhibitors | Pregnant women | Prostaglandins E | Genes | Genetic research | Interferon | Biological response modifiers | Spleen | Immunohistochemistry | Estrus | Immune response | Immunoregulation | Paracrine signalling | mRNA | Estrus cycle | Gene expression | Prostaglandin endoperoxide synthase | Proteins | Immune systems | Cords | Prostaglandins | Uterus | Cyclooxygenase-1 | Sheep | Dimers | Prostaglandin E | Autocrine signalling | Reductase | Index Medicus
Journal Article
Journal Article
Reproduction, ISSN 1470-1626, 2018, Volume 155, Issue 3, pp. 251 - 258
In the latter half of gestation in the mare, progesterone concentrations decline to near undetectable levels while other 5 alpha-reduced pregnanes are... 
REPRODUCTIVE BIOLOGY | PROGESTERONE | BLOOD-PLASMA | COWS | DEVELOPMENTAL BIOLOGY | FETAL | PARTURITION | EQUINE | RETAINED PLACENTA | MASS-SPECTROMETRY | 5-ALPHA-DIHYDROPROGESTERONE | DUTASTERIDE | Index Medicus
Journal Article
The New Phytologist, ISSN 0028-646X, 2/2010, Volume 185, Issue 3, pp. 687 - 700
The stereospecific 5β-reduction of progesterone is a required step for cardiac glycoside biosynthesis in foxglove plants. Recently, we have isolated the gene... 
Enzymes | Leaves | Complementary DNA | RNA | Metabolites | Genes | Cardenolides | Biosynthesis | Biochemistry | Plants | heterologous protein induction | plant defense | short‐chain dehydrogenase/reductase (SDR) family | cardenolide biosynthesis | teroid 5β‐reductase | wounding and abiotic stress | Short-chain dehydrogenase/reductase (SDR) family | Cardenolide biosynthesis | Heterologous protein induction | Plant defense | Wounding and abiotic stress | Steroid 5β-reductase | SHOOT CULTURES | SECONDARY METABOLISM | short-chain dehydrogenase/reductase (SDR) family | TISSUE-CULTURES | PROGESTERONE 5-BETA-REDUCTASE | PLANT SCIENCES | SHORT-CHAIN DEHYDROGENASES/REDUCTASES | PURPUREA | DIGITALIS-LANATA EHRH | ENZYME | steroid 5 beta-reductase | OBSCURA | EXPRESSION | Digitalis - genetics | Amino Acid Sequence | Oxidoreductases - metabolism | Oxidoreductases - genetics | Cardenolides - metabolism | RNA, Messenger - genetics | DNA, Complementary - genetics | Digitalis - immunology | Models, Molecular | Molecular Sequence Data | Gene Expression Profiling | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Oxidoreductases - chemistry | Sequence Analysis, DNA | Metabolic Networks and Pathways | Genes, Plant - genetics | Digitalis - enzymology | Cloning, Molecular | Gene Expression Regulation, Plant | Kinetics | Index Medicus
Journal Article