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Toxicology and Applied Pharmacology, ISSN 0041-008X, 2004, Volume 201, Issue 3, pp. 226 - 294
Experience with dose response and mechanisms of toxicity has shown that multiple mechanisms may exist for a single agent along the continuum of the full... 
Mechanisms of toxicity | Dose response | Formaldehyde | Zinc | Progesterone/hydroxyflutamide | Propylene oxide | Dose-dependent transitions | Peroxisome proliferator-activated receptor | Acetaminophen | Vinylidene chloride | Butadiene, ethylene glycol | Methylene chloride | Vinyl acetate | Vinyl chloride | Manganese | Progesterone/ hydroxyflutamide | ACETAMINOPHEN-INDUCED HEPATOTOXICITY | propylene oxide | ACTIVATED RECEPTOR-GAMMA | dose-dependent transitions | mechanisms of toxicity | vinylidene chloride | manganese | butadiene | INDUCED HEPATIC-NECROSIS | dose response | ethylene glycol | methylene chloride | PHARMACOLOGY & PHARMACY | TOXICOLOGY | peroxisome proliferator-activated receptor | vinyl acetate | zinc | SISTER-CHROMATID EXCHANGES | SPRAGUE-DAWLEY RATS | MANGANESE OXIDE AEROSOL | formaldehyde | CHRONIC INHALATION TOXICITY | PROTEIN CROSS-LINKS | acetaminophen | vinyl chloride | GLUTATHIONE-S-TRANSFERASE | PARA-BENZOQUINONE IMINE | progesterone/hydroxyflutamide | Analgesics, Non-Narcotic - pharmacokinetics | Progesterone - administration & dosage | Humans | Acetaminophen - administration & dosage | Epoxy Compounds - pharmacokinetics | Dichloroethylenes - toxicity | Manganese - pharmacokinetics | Methylene Chloride - administration & dosage | Analgesics, Non-Narcotic - toxicity | Manganese - administration & dosage | Dichloroethylenes - pharmacokinetics | Dichloroethylenes - administration & dosage | Formaldehyde - toxicity | Androgen Antagonists - toxicity | Ethylene Glycol - toxicity | Butadienes - toxicity | Androgen Antagonists - pharmacokinetics | Progesterone - pharmacokinetics | Oxidation-Reduction | Acetaminophen - toxicity | Vinyl Compounds - administration & dosage | Zinc - toxicity | Androgen Antagonists - administration & dosage | Flutamide - administration & dosage | Vinyl Compounds - toxicity | Zinc - administration & dosage | Peroxisome Proliferator-Activated Receptors - physiology | Drug-Related Side Effects and Adverse Reactions - chemically induced | Flutamide - toxicity | Drug-Related Side Effects and Adverse Reactions - metabolism | Vinyl Compounds - pharmacokinetics | Dose-Response Relationship, Drug | Methylene Chloride - toxicity | Zinc - pharmacokinetics | Epoxy Compounds - administration & dosage | Formaldehyde - administration & dosage | Ethylene Glycol - administration & dosage | Formaldehyde - pharmacokinetics | Ethylene Glycol - pharmacokinetics | Butadienes - pharmacokinetics | Flutamide - analogs & derivatives | Analgesics, Non-Narcotic - administration & dosage | Epoxy Compounds - toxicity | Animals | Butadienes - administration & dosage | Progesterone - toxicity | Methylene Chloride - pharmacokinetics | Acetaminophen - pharmacokinetics | Flutamide - pharmacokinetics | Manganese Poisoning - metabolism
Journal Article
Journal Article
Toxicological Sciences, ISSN 1096-6080, 2002, Volume 66, Issue 1, pp. 69 - 81
The U.S. Environmental Protection Agency has proposed that in vitro assays for estrogen receptor (ER)- and androgen receptor (AR)-mediated actions be included... 
Endocrine screening | Procymidone | Vinclozolin | Linuron | p′,p-DDE | Androgen receptor | Glucocorticoid receptor | HPTE | Antiandrogen | Stable cell line | glucocorticoid receptor | ACTIVATION | stable cell line | PROGESTERONE | REPRODUCTIVE MALFORMATIONS | MEDROXYPROGESTERONE ACETATE | MECHANISMS | vinclozolin | p ',p-DDE | procymidone | PROGESTINS | HYDROXYFLUTAMIDE | BREAST-CANCER CELLS | androgen receptor | antiandrogen | PHARMACOLOGY | ESTROGEN | TOXICOLOGY | endocrine screening | linuron | Androgen Receptor Antagonists | Receptors, Glucocorticoid - antagonists & inhibitors | Corticosterone - pharmacology | Luciferases - metabolism | Gene Expression - drug effects | Humans | Receptors, Androgen - metabolism | Estrogen Antagonists - pharmacology | Receptors, Glucocorticoid - metabolism | Promoter Regions, Genetic - genetics | Recombinant Fusion Proteins - metabolism | Recombinant Fusion Proteins - drug effects | Luciferases - genetics | Receptors, Glucocorticoid - agonists | Dose-Response Relationship, Drug | Dexamethasone - pharmacology | Plasmids - genetics | Molecular Structure | Progesterone - pharmacology | Estradiol - pharmacology | Luciferases - drug effects | Tumor Cells, Cultured - drug effects | Androgen Antagonists - pharmacology | Tumor Cells, Cultured - metabolism | Androgens | Glucocorticoids - pharmacology | Recombinant Fusion Proteins - genetics | Mammary Tumor Virus, Mouse - genetics | Pesticides - pharmacology
Journal Article
Journal Article
Journal of Reproduction and Fertility, ISSN 0022-4251, 1993, Volume 99, Issue 2, pp. 467 - 470
Journal Article
Journal Article
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, ISSN 0008-4212, 09/1991, Volume 69, Issue 9, pp. 1288 - 1293
Serum and ovarian progesterone levels and in vitro production of progesterone by preovulatory follicles were measured on proestrus in pregnant mare's serum... 
LUTEINIZING HORMONE | PHYSIOLOGY | PROGESTERONE | GRANULOSA-CELLS | HORMONE-RELEASING HORMONE | LUTEINIZING-HORMONE | HYDROXYFLUTAMIDE | ANTIANDROGEN | HUMAN CHORIONIC GONADOTROPIN | OVULATION | SURGE | STIMULATORY ACTION | PHARMACOLOGY & PHARMACY | IMMATURE RATS | ANDROGENS | GONADOTROPIN | ESTROUS-CYCLE
Journal Article
JOURNAL OF REPRODUCTION AND FERTILITY, ISSN 0022-4251, 11/1993, Volume 99, Issue 2, pp. 467 - 470
Hydroxyflutamide is a potent nonsteroidal anti-androgenic drug extensively used in laboratory investigations. Our present studies were aimed at determining... 
REPRODUCTIVE BIOLOGY | PRIMED IMMATURE RATS | PROGESTERONE | ANTIANDROGEN | INVITRO | GROWTH-FACTORS | OVULATION | SURGE | INTERFERENCE | BINDING | LUTEINIZING-HORMONE
Journal Article
Journal of Reproduction and Fertility, ISSN 0022-4251, 1989, Volume 85, Issue 1, pp. 309 - 316
In Exp. 1, PMSG was injected to 26-day-old prepubertal rats to induce ovulations. On Day 2 (2 days later, the equivalent of the day of pro-oestrus) they... 
REPRODUCTIVE BIOLOGY | Gonadotropins, Equine - pharmacology | Animals | Anilides - pharmacology | Flutamide - analogs & derivatives | Rats | Female | Ovulation - drug effects | Luteinizing Hormone - metabolism | Rats, Inbred Strains | Progesterone - pharmacology | Flutamide - pharmacology | Sexual Maturation
Journal Article
by X Zhang and B A Croy
Biology of Reproduction, ISSN 0006-3363, 09/1996, Volume 55, Issue 3, pp. 519 - 524
Journal Article
Journal Article