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Blood, ISSN 0006-4971, 2013, Volume 122, Issue 17, pp. 3062 - 3073
Programmed death 1 (PD-1) and its ligands, PD-L1 and PD-L2, play an important role in the maintenance of peripheral tolerance. We explored the role of PD-1... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | BONE-MARROW-TRANSPLANTATION | T-CELL-ACTIVATION | GASTROINTESTINAL-TRACT | ENDOTHELIAL-CELLS | IN-VIVO | TNF-ALPHA | HEMATOLOGY | PD-1 | GAMMA-DEPENDENT MECHANISM | LYMPHOCYTES | Glucose Transport Proteins, Facilitative - metabolism | Liver - pathology | Cell Proliferation | Spleen - immunology | Programmed Cell Death 1 Ligand 2 Protein - metabolism | Intestines - metabolism | Graft vs Host Disease - metabolism | CD4-Positive T-Lymphocytes - pathology | Graft vs Host Disease - immunology | Intestines - immunology | CD4-Positive T-Lymphocytes - immunology | Liver - immunology | Glucose Transport Proteins, Facilitative - immunology | Graft vs Host Disease - mortality | Bone Marrow Transplantation | Apoptosis Regulatory Proteins - genetics | Glucose Transport Proteins, Facilitative - genetics | Spleen - pathology | Transplantation Tolerance - immunology | Acute Disease | Apoptosis Regulatory Proteins - immunology | Intestines - pathology | Programmed Cell Death 1 Ligand 2 Protein - genetics | Liver - metabolism | CD4-Positive T-Lymphocytes - metabolism | Gene Expression Regulation | Oxidative Phosphorylation | Programmed Cell Death 1 Receptor - metabolism | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Apoptosis Regulatory Proteins - metabolism | Graft vs Host Disease - pathology | Programmed Cell Death 1 Ligand 2 Protein - immunology | B7-H1 Antigen - metabolism | Animals | Spleen - metabolism | Peripheral Tolerance - immunology | Survival Analysis | Glycolysis | Mice | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | Index Medicus | Abridged Index Medicus | Transplantation
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2014, Volume 20, Issue 19, pp. 5064 - 5074
Journal Article
Cancer Science, ISSN 1347-9032, 11/2016, Volume 107, Issue 11, pp. 1696 - 1704
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2015, Volume 372, Issue 4, pp. 311 - 319
Journal Article
Cell Reports, ISSN 2211-1247, 05/2017, Volume 19, Issue 6, pp. 1189 - 1201
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2013, Volume 288, Issue 17, pp. 11771 - 11785
PD-1, a receptor expressed by T cells, B cells, and monocytes, is a potent regulator of immune responses and a promising therapeutic target. The structure and... 
RHEUMATOID-ARTHRITIS | SECONDARY STRUCTURE DETERMINATION | NMR ASSIGNMENT | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-TERMINAL DOMAIN | TISSUE INHIBITOR | QUANTITATIVE-ANALYSIS | MOLECULAR-BASIS | T-CELLS | PD-1 EXPRESSION | Surface Plasmon Resonance | Cell Communication - immunology | Programmed Cell Death 1 Receptor - chemistry | B7-1 Antigen - genetics | Humans | Programmed Cell Death 1 Ligand 2 Protein - metabolism | Structure-Activity Relationship | B7-H1 Antigen - chemistry | Programmed Cell Death 1 Ligand 2 Protein - chemistry | T-Lymphocytes - metabolism | B7-1 Antigen - chemistry | Nuclear Magnetic Resonance, Biomolecular | Antigen-Presenting Cells - metabolism | Protein Structure, Secondary | B7-1 Antigen - immunology | Programmed Cell Death 1 Ligand 2 Protein - genetics | Programmed Cell Death 1 Receptor - metabolism | B7-1 Antigen - metabolism | Antigen-Presenting Cells - immunology | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Programmed Cell Death 1 Ligand 2 Protein - immunology | Antigen-Presenting Cells - chemistry | B7-H1 Antigen - metabolism | Models, Immunological | Animals | T-Lymphocytes - chemistry | Protein Binding | T-Lymphocytes - immunology | Mice | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | Index Medicus | Nuclear Magnetic Resonance | Signaling | Thermodynamics | Receptors | Immunology | Surface Plasmon Resonance (SPR) | Cell Surface Protein | Complex Formation | Affinity | Naturvetenskap | Natural Sciences
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 08/2016, Volume 34, Issue 23, pp. 2698 - 2704
Purpose Cancer cells can exploit the programmed death-1 (PD-1) immune checkpoint pathway to avoid immune surveillance by modulating T-lymphocyte activity. In... 
MULTIPLE-MYELOMA | B-CELL LYMPHOMA | B7-H1 PD-L1 | RESPONSE CRITERIA | ONCOLOGY | ADVANCED MELANOMA | ANTIBODY | BLOCKADE | EXPRESSION | CANCER | IPILIMUMAB | T-Lymphocytes - physiology | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Programmed Cell Death 1 Ligand 2 Protein - metabolism | Male | Antineoplastic Agents - administration & dosage | Lymphoma, B-Cell - genetics | Young Adult | Mycosis Fungoides - pathology | Multiple Myeloma - drug therapy | Antineoplastic Agents - adverse effects | Pneumonia - chemically induced | T-Lymphocytes - drug effects | Aged, 80 and over | Biomarkers, Tumor - metabolism | Adult | Female | Mycosis Fungoides - genetics | Lymphoma, B-Cell - drug therapy | Programmed Cell Death 1 Ligand 2 Protein - genetics | Treatment Outcome | Chromosomes, Human, Pair 9 | Lymphoma, T-Cell - genetics | B7-H1 Antigen - genetics | Mycosis Fungoides - drug therapy | Retreatment | B7-H1 Antigen - metabolism | Lymphoma, T-Cell - drug therapy | Multiple Myeloma - pathology | Antibodies, Monoclonal - administration & dosage | Lymphocyte Activation - drug effects | Chromosome Aberrations | Lymphoma, B-Cell - pathology | Lymphoma, T-Cell - pathology | Aged | Biomarkers, Tumor - genetics | Cell Proliferation - drug effects | Multiple Myeloma - genetics | Index Medicus | ORIGINAL REPORTS | Pedi11
Journal Article
Immunity, ISSN 1074-7613, 08/2016, Volume 45, Issue 2, pp. 333 - 345
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2016, Volume 113, Issue 48, pp. E7769 - E7777
Journal Article