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Journal of allergy and clinical immunology, ISSN 0091-6749, 2017, Volume 139, Issue 1, pp. 335 - 346.e3
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 2015, Volume 125, Issue 5, pp. 2046 - 2058
T cell Ig and ITIM domain (TIGIT) is an inhibitory receptor expressed by activated T cells, Tregs, and NI( cells... 
MEDICINE, RESEARCH & EXPERIMENTAL | ADHESION MOLECULE | LIGANDS | DNAM-1 | INHIBITORY RECEPTORS | CHRONIC VIRAL-INFECTION | NECTIN-2 CD112 | UP-REGULATION | PVR CD155 | EXPRESSION | POLIOVIRUS RECEPTOR CD155 | Up-Regulation | Receptors, Immunologic - physiology | Receptors, Virus - biosynthesis | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Neoplasm Proteins - antagonists & inhibitors | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Programmed Cell Death 1 Receptor - physiology | Receptors, Virus - genetics | Receptors, Immunologic - antagonists & inhibitors | Receptors, Immunologic - biosynthesis | Programmed Cell Death 1 Receptor - biosynthesis | CD8-Positive T-Lymphocytes - metabolism | Lymphocytes, Tumor-Infiltrating - metabolism | Interleukin-2 Receptor beta Subunit - genetics | Neoplasm Proteins - genetics | Antibodies, Monoclonal - immunology | Antigen-Presenting Cells - metabolism | Antigens, Neoplasm - immunology | Lymphocyte Activation | Neoplasm Proteins - biosynthesis | Antibodies, Monoclonal - pharmacology | Immunophenotyping | Interleukin-2 Receptor beta Subunit - biosynthesis | Melanoma - pathology | Antigen-Presenting Cells - immunology | Melanoma - immunology | Antigens, Differentiation, T-Lymphocyte - genetics | Cell Line, Tumor | T-Cell Antigen Receptor Specificity | Immunologic Memory | Antigens, Differentiation, T-Lymphocyte - biosynthesis | CD8-Positive T-Lymphocytes - immunology | Receptors, Immunologic - genetics | Programmed Cell Death 1 Receptor - genetics | Cytokines - biosynthesis | Lymphocytes, Tumor-Infiltrating - immunology | Oncology | Immunology | Dermatology | Therapeutics
Journal Article
Cancer, ISSN 0008-543X, 2017, Volume 123, Issue 17, pp. 3291 - 3304
.... Gene expression, immunohistochemistry for programmed cell death protein (PD‐1) and programmed death‐ligand 1 (PD‐L1), and T‐cell receptor Vβ... 
leiomyosarcoma | sarcoma | pleomorphic | programmed death‐ligand 1 (PD‐L1) | T‐cell receptors | immunotherapy | liposarcoma | gene expression | programmed cell death protein (PD‐1) | T-cell receptors | programmed cell death protein (PD-1) | programmed death-ligand 1 (PD-L1) | NY-ESO-1 | PAZOPANIB | DOXORUBICIN | CANCER | TRIAL | ONCOLOGY | EUROPEAN-ORGANIZATION | BLOCKADE | LYMPHOCYTES | Immunohistochemistry | Prognosis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Sarcoma - therapy | Young Adult | Neoplasm Invasiveness - pathology | Sarcoma - mortality | Aged, 80 and over | Adult | Female | Clone Cells | Retrospective Studies | Sarcoma - genetics | Soft Tissue Neoplasms - genetics | Databases, Factual | Soft Tissue Neoplasms - therapy | Soft Tissue Neoplasms - mortality | Combined Modality Therapy | Sarcoma - pathology | Disease-Free Survival | Analysis of Variance | T-Lymphocytes - cytology | Soft Tissue Neoplasms - pathology | Survival Analysis | T-Lymphocytes - immunology | Aged | Biopsy, Needle | Neoplasm Staging | Programmed Cell Death 1 Receptor - genetics | Cluster Analysis | Cohort Studies | Care and treatment | Sarcoma | Cell death | Analysis | Research | Diagnosis | Gene expression | PD-1 protein | Lymphocytes T | Paraffin | Formaldehyde | Metastases | Gene sequencing | T-cell receptor | Immunotherapy | Immune system | Antigen presentation | Antigens | Immune response | Synovial sarcoma | Mortality | Soft tissue sarcoma | Autoantigens | Inflammation | T cell receptors | Patients | Immune checkpoint | Immunogenicity | PD-L1 protein | Liposarcoma | Ligands | Infiltration | Cancer | Tumors | Apoptosis | Original
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2013, Volume 288, Issue 17, pp. 11771 - 11785
PD-1, a receptor expressed by T cells, B cells, and monocytes, is a potent regulator of immune responses and a promising therapeutic target... 
SECONDARY STRUCTURE DETERMINATION | NMR ASSIGNMENT | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-TERMINAL DOMAIN | TISSUE INHIBITOR | QUANTITATIVE-ANALYSIS | MOLECULAR-BASIS | HCV INFECTION | T-CELLS | PD-1 EXPRESSION | Surface Plasmon Resonance | Cell Communication - immunology | Programmed Cell Death 1 Receptor - chemistry | B7-1 Antigen - genetics | Humans | Programmed Cell Death 1 Ligand 2 Protein - metabolism | Structure-Activity Relationship | B7-H1 Antigen - chemistry | Programmed Cell Death 1 Ligand 2 Protein - chemistry | T-Lymphocytes - metabolism | B7-1 Antigen - chemistry | Nuclear Magnetic Resonance, Biomolecular | Antigen-Presenting Cells - metabolism | Protein Structure, Secondary | B7-1 Antigen - immunology | Programmed Cell Death 1 Ligand 2 Protein - genetics | Programmed Cell Death 1 Receptor - metabolism | B7-1 Antigen - metabolism | Antigen-Presenting Cells - immunology | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Programmed Cell Death 1 Ligand 2 Protein - immunology | Antigen-Presenting Cells - chemistry | B7-H1 Antigen - metabolism | Models, Immunological | Animals | T-Lymphocytes - chemistry | Protein Binding | T-Lymphocytes - immunology | Mice | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | Nuclear Magnetic Resonance | Signaling | Thermodynamics | Receptors | Immunology | Surface Plasmon Resonance (SPR) | Cell Surface Protein | Complex Formation | Affinity
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 1, p. e55818
...), expression of programmed death receptor ligand 1/programmed death receptor 1 (PD-L1/PD-1), arginase 1 and soluble CD25... 
INTERLEUKIN-2-RECEPTOR | B7-H1 PD-L1 | ARGINASE | TUMOR BURDEN | SAFETY | MULTIDISCIPLINARY SCIENCES | IMATINIB | ANTIBODY | PHASE-I | CANCER | CLINICAL-SIGNIFICANCE | Antigens, CD34 - metabolism | Humans | Middle Aged | Arginase - metabolism | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Young Adult | Lymphocyte Activation - immunology | T-Lymphocytes - metabolism | Myeloid Cells - immunology | Adult | Female | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - immunology | Interleukin-2 Receptor alpha Subunit - blood | Programmed Cell Death 1 Receptor - metabolism | Gene Expression Regulation, Leukemic | B7-H1 Antigen - metabolism | Interleukin-2 Receptor alpha Subunit - metabolism | Adolescent | Cell Line, Tumor | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Myeloid Cells - metabolism | T-Lymphocytes - immunology | Aged | Programmed Cell Death 1 Receptor - genetics | Medical research | Care and treatment | Immunotherapy | Medicine, Experimental | Development and progression | Interferon | Chronic myeloid leukemia | T cells | Risk factors | Cancer | Cell proliferation | Disease | PD-1 protein | Laboratories | Leukemia | Science | Clinical trials | Risk | Arginase | Lymphocytes T | Kinases | Suppressor cells | Ethics | Immunology | Interleukin 2 | Lymphocytes | Cell cycle | CD25 antigen | Protein-tyrosine kinase | Immune system | Tyrosine | CD34 antigen | Myeloid cells | Cytokines | Hematology | Myeloid leukemia | Mortality | Blood banks | Patients | Studies | Pathology | Hospitals | Medical prognosis | PD-L1 protein | Stem cells | Ligands | Death | Lymphomas | Apoptosis
Journal Article
Journal of thoracic oncology, ISSN 1556-0864, 2015, Volume 10, Issue 6, pp. 910 - 923
Epidermal growth factor receptor (EGFR) mutation status was reported to be associated with programmed death-ligand 1 (PD-L1) expression... 
PD-L1 | NSCLC | PD-1 | EGFR | Tyrosine kinase inhibitors | LUNG | CELLS | B7-H1 EXPRESSION | DEATH-LIGAND 1 | MELANOMA | ONCOLOGY | PATHWAY | IMMUNOTHERAPY | RESPIRATORY SYSTEM | POOR-PROGNOSIS | GROWTH | INHIBITORS | Tumor Escape - drug effects | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Sequence Deletion | Up-Regulation | Exons | Humans | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Molecular Targeted Therapy | Receptor, Epidermal Growth Factor - metabolism | T-Lymphocytes - pathology | Lung Neoplasms - genetics | Receptor, Epidermal Growth Factor - immunology | Lung Neoplasms - enzymology | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Programmed Cell Death 1 Receptor - metabolism | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Carcinoma, Non-Small-Cell Lung - immunology | B7-H1 Antigen - metabolism | Lung Neoplasms - immunology | Apoptosis - immunology | B7-H1 Antigen - antagonists & inhibitors | Interferon-gamma - immunology | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | T-Lymphocytes - immunology | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | Interferon-gamma - biosynthesis
Journal Article
Cytotherapy (Oxford, England), ISSN 1465-3249, 2018, Volume 20, Issue 10, pp. 1259 - 1266
...). When activated, T cells express associated “checkpoint” receptors. Binding of co-inhibitory ligands and receptors may directly contribute to T-cell functional exhaustion... 
Advanced Basic Science | Other | immune evasion | chimeric antigen receptor–T cells | adoptive cell therapy | cancer immunotherapy | immune checkpoint blockade | MEDICINE, RESEARCH & EXPERIMENTAL | AUGMENTS | SOLID TUMORS | EFFICACY | PD-1 BLOCKADE | ACUTE MYELOID-LEUKEMIA | chimeric antigen receptor-T cells | CELL & TISSUE ENGINEERING | CELL BIOLOGY | B-CELL | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | CAR-T-CELLS | HEMATOLOGY | ANTIGEN RECEPTOR | EXHAUSTION | T-Lymphocytes - physiology | Humans | Hepatitis A Virus Cellular Receptor 2 - metabolism | Tumor Microenvironment | CD28 Antigens - genetics | Cytotoxicity Tests, Immunologic - methods | Hepatitis A Virus Cellular Receptor 2 - immunology | Leukemia, Myeloid, Acute - therapy | Immunotherapy, Adoptive - methods | Receptors, Antigen, T-Cell - metabolism | Leukemia, Myeloid, Acute - pathology | Lymphocyte Activation | Programmed Cell Death 1 Receptor - metabolism | CD28 Antigens - immunology | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | B7-H1 Antigen - metabolism | Genetic Engineering | Interleukin-3 Receptor alpha Subunit - genetics | Receptors, Chimeric Antigen - immunology | K562 Cells | Cell Line, Tumor | Receptors, Chimeric Antigen - genetics | T-Lymphocytes - immunology | Programmed Cell Death 1 Receptor - immunology
Journal Article