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Journal Article
Immunity, ISSN 1074-7613, 08/2016, Volume 45, Issue 2, pp. 358 - 373
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 06/2015, Volume 10, Issue 6, pp. 910 - 923
Epidermal growth factor receptor (EGFR) mutation status was reported to be associated with programmed death-ligand 1 (PD-L1) expression. However, the molecular... 
PD-L1 | NSCLC | PD-1 | EGFR | Tyrosine kinase inhibitors | LUNG | CELLS | B7-H1 EXPRESSION | DEATH-LIGAND 1 | MELANOMA | ONCOLOGY | PATHWAY | IMMUNOTHERAPY | RESPIRATORY SYSTEM | POOR-PROGNOSIS | GROWTH | INHIBITORS | Tumor Escape - drug effects | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Sequence Deletion | Up-Regulation | Exons | Humans | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Molecular Targeted Therapy | Receptor, Epidermal Growth Factor - metabolism | T-Lymphocytes - pathology | Lung Neoplasms - genetics | Receptor, Epidermal Growth Factor - immunology | Lung Neoplasms - enzymology | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Programmed Cell Death 1 Receptor - metabolism | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Carcinoma, Non-Small-Cell Lung - immunology | B7-H1 Antigen - metabolism | Lung Neoplasms - immunology | Apoptosis - immunology | B7-H1 Antigen - antagonists & inhibitors | Interferon-gamma - immunology | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | T-Lymphocytes - immunology | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | Interferon-gamma - biosynthesis | Index Medicus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2015, Volume 212, Issue 2, pp. 139 - 148
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2013, Volume 288, Issue 17, pp. 11771 - 11785
PD-1, a receptor expressed by T cells, B cells, and monocytes, is a potent regulator of immune responses and a promising therapeutic target. The structure and... 
RHEUMATOID-ARTHRITIS | SECONDARY STRUCTURE DETERMINATION | NMR ASSIGNMENT | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-TERMINAL DOMAIN | TISSUE INHIBITOR | QUANTITATIVE-ANALYSIS | MOLECULAR-BASIS | T-CELLS | PD-1 EXPRESSION | Surface Plasmon Resonance | Cell Communication - immunology | Programmed Cell Death 1 Receptor - chemistry | B7-1 Antigen - genetics | Humans | Programmed Cell Death 1 Ligand 2 Protein - metabolism | Structure-Activity Relationship | B7-H1 Antigen - chemistry | Programmed Cell Death 1 Ligand 2 Protein - chemistry | T-Lymphocytes - metabolism | B7-1 Antigen - chemistry | Nuclear Magnetic Resonance, Biomolecular | Antigen-Presenting Cells - metabolism | Protein Structure, Secondary | B7-1 Antigen - immunology | Programmed Cell Death 1 Ligand 2 Protein - genetics | Programmed Cell Death 1 Receptor - metabolism | B7-1 Antigen - metabolism | Antigen-Presenting Cells - immunology | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Programmed Cell Death 1 Ligand 2 Protein - immunology | Antigen-Presenting Cells - chemistry | B7-H1 Antigen - metabolism | Models, Immunological | Animals | T-Lymphocytes - chemistry | Protein Binding | T-Lymphocytes - immunology | Mice | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | Index Medicus | Nuclear Magnetic Resonance | Signaling | Thermodynamics | Receptors | Immunology | Surface Plasmon Resonance (SPR) | Cell Surface Protein | Complex Formation | Affinity | Naturvetenskap | Natural Sciences
Journal Article
Cancer Research, ISSN 0008-5472, 06/2013, Volume 73, Issue 12, pp. 3591 - 3603
Tumor progression is facilitated by regulatory T cells (Treg) and restricted by effector T cells. In this study, we document parallel regulation of CD8(+) T... 
DISTINCT MECHANISMS | ONCOLOGY | PROGRAMMED DEATH-1 | IMMUNE ESCAPE | MYELOID-LEUKEMIA | SYNGENEIC MOUSE MODEL | REGULATORY T | GROWTH-FACTOR | CHRONIC VIRAL-INFECTION | ANTITUMOR-ACTIVITY | HUMAN OVARIAN-CANCER | T-Lymphocytes, Regulatory - metabolism | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antibodies, Blocking - pharmacology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Neoplasms, Experimental - pathology | Flow Cytometry | T-Lymphocytes - metabolism | Neoplasms, Experimental - immunology | CD8-Positive T-Lymphocytes - metabolism | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Cytokines - immunology | Cytokines - metabolism | Cancer Vaccines - administration & dosage | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Neoplasms, Experimental - therapy | CTLA-4 Antigen - metabolism | Lymphocytes, Tumor-Infiltrating - transplantation | Programmed Cell Death 1 Receptor - metabolism | Combined Modality Therapy | CTLA-4 Antigen - immunology | B7-H1 Antigen - immunology | Cancer Vaccines - immunology | B7-H1 Antigen - metabolism | Animals | Antibodies, Blocking - immunology | T-Lymphocytes - immunology | Mice | Mice, Inbred BALB C | Programmed Cell Death 1 Receptor - immunology | CD8-Positive T-Lymphocytes - immunology | CTLA-4 Antigen - antagonists & inhibitors | Lymphocytes, Tumor-Infiltrating - immunology | Tumor Burden - immunology | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2016, Volume 126, Issue 9, pp. 3447 - 3452
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2015, Volume 372, Issue 4, pp. 311 - 319
Journal Article