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The Journal of clinical investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 2046 - 2058
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Up-Regulation | Receptors, Immunologic - physiology | Receptors, Virus - biosynthesis | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Neoplasm Proteins - antagonists & inhibitors | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Programmed Cell Death 1 Receptor - physiology | Receptors, Virus - genetics | Receptors, Immunologic - antagonists & inhibitors | Receptors, Immunologic - biosynthesis | Programmed Cell Death 1 Receptor - biosynthesis | CD8-Positive T-Lymphocytes - metabolism | Lymphocytes, Tumor-Infiltrating - metabolism | Interleukin-2 Receptor beta Subunit - genetics | Neoplasm Proteins - genetics | Antibodies, Monoclonal - immunology | Antigen-Presenting Cells - metabolism | Antigens, Neoplasm - immunology | Lymphocyte Activation | Neoplasm Proteins - biosynthesis | Antibodies, Monoclonal - pharmacology | Immunophenotyping | Interleukin-2 Receptor beta Subunit - biosynthesis | Melanoma - pathology | Antigen-Presenting Cells - immunology | Melanoma - immunology | Antigens, Differentiation, T-Lymphocyte - genetics | Cell Line, Tumor | T-Cell Antigen Receptor Specificity | Immunologic Memory | Antigens, Differentiation, T-Lymphocyte - biosynthesis | CD8-Positive T-Lymphocytes - immunology | Receptors, Immunologic - genetics | Programmed Cell Death 1 Receptor - genetics | Cytokines - biosynthesis | Lymphocytes, Tumor-Infiltrating - immunology | Index Medicus | Abridged Index Medicus | Oncology | Immunology | Dermatology | Therapeutics
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 03/2013, Volume 123, Issue 3, pp. 1044 - 1065
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Phosphorylation | Humans | Transcriptome | MicroRNAs - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Programmed Cell Death 1 Receptor - physiology | Signal Transduction - immunology | ZAP-70 Protein-Tyrosine Kinase - metabolism | Cell Line | HLA-A2 Antigen - immunology | Immunotherapy, Adoptive | Antigens, Neoplasm - immunology | Lymphocyte Activation | Programmed Cell Death 1 Receptor - metabolism | Membrane Proteins - immunology | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | Receptors, Antigen, T-Cell, alpha-beta - genetics | CD8-Positive T-Lymphocytes - physiology | CD8-Positive T-Lymphocytes - enzymology | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Down-Regulation - immunology | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - antagonists & inhibitors | Antimony Sodium Gluconate - pharmacology | Protein Binding | MicroRNAs - genetics | Protein Processing, Post-Translational | Receptors, Antigen, T-Cell, alpha-beta - metabolism | CD8-Positive T-Lymphocytes - immunology | Programmed Cell Death 1 Receptor - genetics | Antigen receptors, T cell | Receptors | Phosphatases | Physiological aspects | Cellular immunity | Genetic aspects | Research | Gene expression | T cells | Index Medicus | Abridged Index Medicus
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 2016, Volume 139, Issue 1, pp. 335 - 346.e3
Allergy and Immunology | natural killer cell degranulation | cytomegalovirus | immune checkpoint | ovarian carcinoma | natural killer cell cytokine production | Natural killer cells | CD57+ natural killer cells | tumor escape | natural killer cell proliferation | programmed death receptor | natural killer cells | CD57 | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Phenotype | Cell Proliferation | Cell Degranulation | Humans | Killer Cells, Natural - immunology | Female | Programmed Cell Death 1 Receptor - immunology | Killer Cells, Natural - physiology | Cytokines - immunology | Ovarian Neoplasms - immunology | T cells | Killer cells | Antigens | Ovarian cancer | Immunoglobulins | Blood & organ donations | Cytokines | Lymphocytes | Cytotoxicity | Ligands | T cell receptors | Viral infections | Tumors | Cancer | Index Medicus | Abridged Index Medicus | Life Sciences | Killer Cells, Natural | Programmed Cell Death 1 Receptor | Ovarian Neoplasms
Journal Article
Journal of hepatology, ISSN 0168-8278, 2014, Volume 61, Issue 6, pp. 1212 - 1219
Gastroenterology and Hepatology | Inhibitory receptors | Virus-specific CD8+ T cells | T cell differentiation | T cell exhaustion | Inactive carrier | HBV | PD-1 | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Hepatitis B - metabolism | Humans | Middle Aged | Cells, Cultured | Hepatitis B - pathology | Programmed Cell Death 1 Receptor - metabolism | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Hepatitis B virus - physiology | CD8-Positive T-Lymphocytes - physiology | Antibodies - pharmacology | Hepatitis B - physiopathology | Signal Transduction - drug effects | CD8-Positive T-Lymphocytes - drug effects | Adult | Female | Signal Transduction - physiology | Aged | Alanine Transaminase - metabolism | Hepatitis B e Antigens - blood | Cell Differentiation - physiology | Programmed Cell Death 1 Receptor - drug effects | Viral Load - physiology | T cells | Cell differentiation | Hepatitis B | Index Medicus
Journal Article
Nature medicine, ISSN 1078-8956, 08/2019, Volume 25, Issue 8, pp. 1251 - 1259
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | T Cell Transcription Factor 1 - physiology | Carcinoma, Squamous Cell - drug therapy | Sequence Analysis, RNA | Humans | Immunotherapy | Carcinoma, Basal Cell - drug therapy | Programmed Cell Death 1 Receptor - antagonists & inhibitors | T-Lymphocytes - immunology | Carcinoma, Basal Cell - immunology | Carcinoma, Squamous Cell - immunology | Receptors, Antigen, T-Cell - physiology | Lymphocytes, Tumor-Infiltrating - immunology | Cancer patients | Care and treatment | Usage | Research | T cells | Phenotypes | Squamous cell carcinoma | Tumor-infiltrating lymphocytes | Transcription | PD-1 protein | CD8 antigen | T cell receptors | Lymphocytes T | Ribonucleic acid--RNA | Gene sequencing | T-cell receptor | Receptors | Cell activation | Immune checkpoint | Lymphocytes | Exhaustion | Expansion | Tumors | Index Medicus
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PD-L1 inhibits acute and chronic pain by suppressing nociceptive neuron activity via PD-1
Nature neuroscience, ISSN 1097-6256, 07/2017, Volume 20, Issue 7, pp. 917 - 926
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Hyperalgesia - chemically induced | Melanoma - blood | Pain Threshold - physiology | Phosphorylation | Synaptic Transmission - physiology | Humans | Male | Sodium Channels - physiology | Programmed Cell Death 1 Receptor - physiology | Neurons - physiology | Programmed Cell Death 1 Receptor - biosynthesis | Pain Threshold - drug effects | Female | Synaptic Transmission - drug effects | Neuralgia - physiopathology | Neurons - drug effects | Melanoma - physiopathology | B7-H1 Antigen - physiology | Cricetinae | Cells, Cultured | Ganglia, Spinal - physiology | Rats | Mice, Knockout | Analgesia | Animals | B7-H1 Antigen - blood | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | B7-H1 Antigen - pharmacology | Potassium Channels, Tandem Pore Domain - physiology | Mice | Primary Cell Culture | Ganglia, Spinal - drug effects | Programmed Cell Death 1 Receptor - genetics | Ganglia, Spinal - metabolism
Journal Article
Leukemia, ISSN 0887-6924, 02/2016, Volume 30, Issue 2, pp. 484 - 491
Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Tumor Escape - drug effects | B7-H1 Antigen - physiology | Antibodies, Bispecific - pharmacology | Leukemia, Myeloid, Acute - pathology | Sialic Acid Binding Ig-like Lectin 3 - analysis | Humans | Programmed Cell Death 1 Receptor - analysis | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Leukemia, Myeloid, Acute - immunology | Programmed Cell Death 1 Receptor - physiology | Animals | B7-H1 Antigen - antagonists & inhibitors | Leukemia, Myeloid, Acute - drug therapy | T-Lymphocytes - immunology | B7-H1 Antigen - analysis | Mice | Gene expression | Cellular proteins | Health aspects | Genetic aspects | Regulation | Immune response | T cells | Index Medicus
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 02/2016, Volume 44, Issue 2, pp. 274 - 286
Life Sciences & Biomedicine | Immunology | Science & Technology | Maleimides - administration & dosage | RNA, Small Interfering - genetics | Maleimides - adverse effects | Lymphocytic Choriomeningitis - immunology | Aminophenols - adverse effects | Lymphocytic choriomeningitis virus - physiology | Rhadinovirus - physiology | Cytotoxicity, Immunologic - drug effects | T-Lymphocytes, Cytotoxic - immunology | Cytotoxicity, Immunologic - genetics | Gene Expression Regulation - genetics | T-Lymphocytes, Cytotoxic - virology | Mice, Inbred C57BL | Cells, Cultured | Programmed Cell Death 1 Receptor - metabolism | Glycogen Synthase Kinase 3 - metabolism | Viral Load - genetics | T-Box Domain Proteins - genetics | T-Box Domain Proteins - metabolism | Gene Expression Regulation - drug effects | Animals | Glycogen Synthase Kinase 3 - genetics | CD8-Positive T-Lymphocytes - virology | Mice | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | Viral Load - drug effects | Programmed Cell Death 1 Receptor - genetics | Aminophenols - administration & dosage | Herpesviridae Infections - immunology | Peptides | Lymphocytes | Efficiency | Viruses | T cell receptors | Kinases | Experiments | Lymphoma | Viral infections | Index Medicus
Journal Article