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Immunity, ISSN 1074-7613, 08/2016, Volume 45, Issue 2, pp. 333 - 345
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2010, Volume 107, Issue 30, pp. 13402 - 13407
The programmed death-1 (PD-1) costimulatory receptor inhibits T and B cell responses and plays a crucial role in peripheral tolerance. PD-1 has recently been... 
T lymphocytes | Lungs | Cytokines | Mycobacterium tuberculosis | B lymphocytes | Pulmonary tuberculosis | Aerosols | Ligands | Infections | Chemokines | Infection | Co-inhibitory | Costimulatory | MYCOBACTERIUM-TUBERCULOSIS | LISTERIA-MONOCYTOGENES | IMMUNE-RESPONSE | costimulatory | infection | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | IMMUNORECEPTOR | PATHWAY | co-inhibitory | T-CELLS | PD-1 EXPRESSION | INNATE IMMUNITY | Immunohistochemistry | Tumor Necrosis Factor-alpha - metabolism | Oligonucleotide Array Sequence Analysis | Mycobacterium tuberculosis - immunology | Male | Tuberculosis - microbiology | Gene Expression Profiling | Host-Pathogen Interactions - immunology | Necrosis | Flow Cytometry | T-Lymphocytes - metabolism | Apoptosis Regulatory Proteins - deficiency | Mycobacterium tuberculosis - physiology | Apoptosis Regulatory Proteins - genetics | Pneumonia - immunology | Female | Lung - metabolism | B-Lymphocytes - pathology | T-Lymphocytes - pathology | B-Lymphocytes - metabolism | Interleukin-1 - metabolism | Apoptosis Regulatory Proteins - immunology | Lung - pathology | Tuberculosis - mortality | Mice, Inbred C57BL | Antigens, Surface - genetics | Survival Rate | Pneumonia - microbiology | Mice, Knockout | Tuberculosis - immunology | Interleukin-17 - metabolism | Animals | B-Lymphocytes - immunology | Lymphocyte Count | Programmed Cell Death 1 Receptor | T-Lymphocytes - immunology | Mice | Pneumonia - metabolism | Antigens, Surface - immunology | Lung - immunology | Tuberculosis | Viral genetics | Development and progression | Genetic aspects | Research | Health aspects | Apoptosis | Cell proliferation | PD-1 protein | Lung | Chronic infection | Inflammation | Leukocytes (neutrophilic) | Lymphocytes T | Immunity | Immunological tolerance | Interleukin 17 | Interleukin 6 | DNA microarrays | Lymphocytes B | Interleukin 1 | Tumor necrosis factor-a | Biological Sciences
Journal Article
Human Reproduction, ISSN 0268-1161, 04/2016, Volume 31, Issue 4, pp. 700 - 711
Abstract STUDY QUESTION Are the immune regulatory molecules programmed cell death-1 (PD-1) and T-cell immunoglobulin mucin-3 (Tim-3) involved in regulating... 
CD4+T | miscarriage | Th2 bias | pregnancy | trophoblast | PD-1 | Tim-3 | ALLOGRAFT-REJECTION | IMMUNITY | PROTECTION | THYMIC STROMAL LYMPHOPOIETIN | OBSTETRICS & GYNECOLOGY | REPRODUCTIVE BIOLOGY | COSTIMULATORY PATHWAYS | CD4(+)T | DIFFERENTIATION | PDL1 | EXHAUSTION | FETOMATERNAL TOLERANCE | Abortion, Habitual - pathology | Fetal Resorption - prevention & control | Coculture Techniques | Humans | Hepatitis A Virus Cellular Receptor 2 - metabolism | Abortion, Habitual - immunology | Fetal Resorption - metabolism | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Th2 Cells - immunology | CD4-Positive T-Lymphocytes - pathology | Abortion, Habitual - metabolism | Pregnancy Trimester, First | Programmed Cell Death 1 Receptor - blood | Th2 Cells - drug effects | Abortion, Induced | CD4-Positive T-Lymphocytes - immunology | Hepatitis A Virus Cellular Receptor 2 - antagonists & inhibitors | Abortion, Habitual - blood | Antibodies, Neutralizing - therapeutic use | Female | Fetal Resorption - pathology | Maternal-Fetal Exchange - drug effects | Th2 Cells - pathology | Immune Tolerance - drug effects | Decidua - immunology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Hepatitis A Virus Cellular Receptor 2 - blood | Programmed Cell Death 1 Receptor - metabolism | Antibodies, Neutralizing - pharmacology | Decidua - pathology | Fetal Resorption - immunology | Th2 Cells - metabolism | Decidua - metabolism | Pregnancy | Tocolytic Agents - pharmacology | Tocolytic Agents - therapeutic use | Animals | Cell Proliferation - drug effects | Mice | Decidua - drug effects | CD4-Positive T-Lymphocytes - drug effects | Crosses, Genetic
Journal Article
Journal Article
Journal Article
Journal Article
Annals of Oncology, ISSN 0923-7534, 02/2016, Volume 27, Issue 2, pp. 300 - 305
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 03/2017, Volume 35, Issue 7, pp. 709 - 717
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 01/2017, Volume 23, Issue 1, pp. 149 - 158
Purpose: Humanized mouse models using NOD/Shi-scid-IL2r gamma(null) (NOG) and NOD/LtSz-scid IL2r gamma(null) (NSG) mouse are associated with several... 
LUNG-CANCER PATIENTS | IMMUNE-SYSTEM | ANTI-PD-1 ANTIBODY | ONCOLOGY | ADVANCED MELANOMA | HEMATOPOIETIC STEM-CELLS | PANCREATIC-CANCER | IN-VIVO | MICE | MODEL | NIVOLUMAB | Immunohistochemistry | Neoplasms - metabolism | Leukocytes, Mononuclear - metabolism | Humans | Programmed Cell Death 1 Receptor - antagonists & inhibitors | T-Lymphocytes, Cytotoxic - drug effects | Neoplasms - genetics | Leukocytes, Mononuclear - immunology | Leukocytes, Mononuclear - transplantation | Killer Cells, Natural - immunology | Lymphocytes, Tumor-Infiltrating - metabolism | Cytokines - genetics | Disease Models, Animal | T-Lymphocytes, Cytotoxic - immunology | Cytokines - metabolism | Immunophenotyping | Histocompatibility Antigens Class I - genetics | Lymphocytes, Tumor-Infiltrating - drug effects | Mice, SCID | Antineoplastic Agents, Immunological - pharmacology | Mice, Knockout | Neoplasms - drug therapy | Animals | T-Lymphocytes, Cytotoxic - metabolism | Survival Analysis | Mice, Inbred NOD | Killer Cells, Natural - drug effects | Mice | Histocompatibility Antigens Class II - genetics | Killer Cells, Natural - metabolism | Neoplasms - pathology | Lymphocytes, Tumor-Infiltrating - immunology | Animal models | Severe combined immunodeficiency | PD-1 protein | CD8 antigen | Glioblastoma | Stem cell transplantation | Leukocytes (mononuclear) | Transplantation | Lymphocytes T | CD45 antigen | Anticancer properties | Lymphocytes | Immunotherapy | Xenografts | Peripheral blood mononuclear cells | Natural killer cells | Spleen | Incubation | Lymphoma | Major histocompatibility complex | Experimental design | Stem cells | Monoclonal antibodies | Antitumor activity | Histocompatibility | Tumors | Cancer | Apoptosis
Journal Article