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DRUG DISCOVERY TODAY, ISSN 1359-6446, 10/2017, Volume 22, Issue 10, pp. 1557 - 1564
Progranulin is a cysteine-rich secreted protein with diverse pleiotropic actions and participates in several processes, such as inflammation or tumorigenesis.... 
BREAST-CANCER | INSULIN-RESISTANCE | ACROGRANIN | PHARMACOLOGY & PHARMACY | CELL-PROLIFERATION | GRANULIN-EPITHELIN PRECURSOR | GROWTH-FACTOR | TNF-ALPHA | EXPRESSION | PLASMA PROGRANULIN | GP88 PROGRANULIN
Journal Article
Cancer Letters, ISSN 0304-3835, 11/2019, Volume 465, pp. 24 - 35
Progranulin (PGRN) is a growth factor with significant biological effects in different types of cancer. However, its role in melanoma progression has not been... 
Natural killer cell | Progranulin | Immune response | CCL5 | Melanoma | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2018, Volume 115, Issue 12, pp. E2849 - E2858
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 12/2018, Volume 72, pp. 171 - 176
There is an unmet need for markers that can stratify different forms and subtypes of dementia. Because of similarities in clinical presentation, it can be... 
Amyloid β-38 | Progranulin | Frontotemporal dementia | Alzheimer's disease | Orexin | C9orf72
Journal Article
Brain, ISSN 0006-8950, 2011, Volume 134, Issue 9, pp. 2565 - 2581
Journal Article
Molecular Genetics and Metabolism, ISSN 1096-7192, 07/2019
Journal Article
Journal of Neuropathology & Experimental Neurology, ISSN 0022-3069, 05/2019, Volume 78, Issue 5, pp. 406 - 415
Abstract Progranulin (PGRN) plays critical roles in inflammation, tumorigenesis, and neurodegeneration. PGRN levels in blood and cerebrospinal fluid (CSF) are... 
Biomarker | Progranulin | Cerebrospinal fluid | Monoclonal antibody | Brain disorders | Double antibody sandwich ELISA (DAS-ELISA) | GRANULIN | EPITHELIN PRECURSOR | ALZHEIMERS-DISEASE | GUIDELINES | SERUM | PATHOLOGY | CEREBROSPINAL-FLUID | NEUROSCIENCES | CLINICAL NEUROLOGY | CASE DEFINITIONS | PLASMA | MONOCLONAL-ANTIBODIES | GROWTH-FACTOR PROGRANULIN
Journal Article
11/2012
Corticobasal Syndrome (CBS) is a rare movement and cognitive disorder. There is significant heterogeneity observed in it clinical presentation, neuroimaging,... 
mutation | movement disorder | Progranulin | 0564 | brain SPECT | dementia | corticobasal syndrome | apraxia | heterogeneity
Dissertation
NeuroImage: Clinical, ISSN 2213-1582, 2018, Volume 19, pp. 497 - 506
Mutations in the progranulin ( ) gene are a major source of inherited frontotemporal degeneration (FTD) spectrum disorders associated with TDP-43... 
Neuroimaging | Presymptomatic | Frontotemporal lobar degeneration | Progranulin | Longitudinal | Magnetic resonance imaging | BRAIN ATROPHY | DEMENTIA | MAGNETIC-RESONANCE IMAGES | FTLD | AMYOTROPHIC-LATERAL-SCLEROSIS | MODEL | VOXEL-BASED MORPHOMETRY | BEHAVIORAL VARIANT | DIFFUSION | Index Medicus
Journal Article
by Deerlin, V.M. Van and Sleiman, P.M.A and Martinez-Lage, M and Chen-Plotkin, A and Wang, L.S and Graff-Radford, N.R and Dickson, D.W and Rademakers, R and Boeve, B.F and Grossman, M and Arnold, S.E and Mann, D.M.A and Pickering-Brown, S.M and Seelaar, H and Heutink, P and Swieten, van, J.C and Murrell, J.R and Ghetti, B and Spina, S and Grafman, J and Hodges, J and Spillantini, M.G and Gilman, S and Lieberman, A.P and Kaye, J.A and Woltjer, R.L and Bigio, E.H and Mesulam, M and Al-Sarraj, S and Troakes, C and Rosenberg, R.N and White, C.L and Ferrer, I and Llado, A and Neumann, M and Kretzschmar, H.A and Hulette, C.M and Welsh-Bohmer, K.A and Miller, B.L and Alzualde, A and Munain, de, A.L and Mckee, A.C and Gearing, M and Levey, A.I and Lah, J.J and Hardy, J and Rohrer, J.D and Lashley, T and Mackenzie, I.R.A and Feldman, H.H and Hamilton, R.L and Dekosky, S.T and Zee, van der, J and Kumar-Singh, S and Broeckhoven, C. Van and Mayeux, R and Vonsattel, J.P.G and Troncoso, J.C and Kril, J.J and Kwok, J.B.J and Halliday, G.M and Bird, T.D and Ince, P.G and Shaw, P.J and Cairns, N.J and Morris, J.C and McLean, C.A and deCarli, C and Ellis, W.G and Freeman, S.H and Frosch, M.P and Growdon, J.H and Perl, D.P and Sano, M and Bennett, D.A and Schneider, J.A and Beach, T.G and Reiman, E.M and Woouff, B.K and Cummings, J and Vinters, H.V and Miller, C.A and Chui, H.C and Alafuzoff, I and Hartikainen, P and Seilhean, D and Galasko, D and Masliah, E and Cotman, C.W and Tunon, M.T and Martinez, M.C.C and Munoz, D.G and Carroll, S.L and Marson, D and Riederer, P.F and Bogdanovic, N and Schellenberg, G.D and Hakonarson, H and Trojanowski, J.Q. and others
Nature Genetics, ISSN 1061-4036, 2010, Volume 42, Issue 3, pp. 234 - U34
Frontotemporal lobar degeneration (FTLD) is the second most common cause of presenile dementia. The predominant neuropathology is FTLD with TAR DNA-binding... 
GENOTYPE DATA | DEMENTIA | FAMILIES | DISEASE | GENETICS & HEREDITY | CONSENSUS | GLOBAL GENE-EXPRESSION | MUTATIONS | PROGRANULIN | ONSET | GENOME-WIDE ASSOCIATION
Journal Article
JOURNAL OF ALZHEIMERS DISEASE, ISSN 1387-2877, 2015, Volume 44, Issue 1, pp. 277 - 282
Mutations in progranulin gene (GRN) are a common cause of autosomal dominant frontotemporal lobar degeneration and are associated with a wide phenotypic... 
mutation | PROGRANULIN MUTATIONS | haploinsufficiency | progranulin (GRN) | Deletion | frontotemporal dementia | NEUROSCIENCES
Journal Article
Human Pathology, ISSN 0046-8177, 2014, Volume 45, Issue 9, pp. 1893 - 1899
Journal Article
Journal of Reproduction and Development, ISSN 0916-8818, 2016
Progranulin (PGRN) is a multifunctional growth factor with functions in neuroprotection, anti-inflammation, and neural progenitor cell proliferation. These... 
Estrogen receptor α | Progranulin | Astrocyte
Journal Article
Alzheimer's Research and Therapy, ISSN 1758-9193, 08/2018, Volume 10, Issue 1, pp. 79 - 79
J