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Journal of Neuroscience, ISSN 0270-6474, 01/2010, Volume 30, Issue 2, pp. 545 - 555
Marijuana is a widely used drug that impairs memory through interaction between its psychoactive constituent, Delta-9-tetrahydrocannabinol (Delta(9)-THC), and... 
CA1 Region, Hippocampal - cytology | Receptor, Adenosine A1 - physiology | Neurons - cytology | Xanthines - pharmacology | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Receptor, Cannabinoid, CB1 - physiology | Excitatory Postsynaptic Potentials - physiology | Quinoxalines - pharmacology | Neural Inhibition - physiology | Receptor, Cannabinoid, CB1 - agonists | Piperidines - pharmacology | Caffeine - pharmacology | Dronabinol - pharmacology | Electric Stimulation - methods | Pyrazoles - pharmacology | Presynaptic Terminals - drug effects | Mice, Inbred C57BL | Morpholines - pharmacology | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Biophysics | Calcium Channel Blockers - pharmacology | GABA Antagonists - pharmacology | Mice, Knockout | Naphthalenes - pharmacology | Methoxyhydroxyphenylglycol - analogs & derivatives | Methoxyhydroxyphenylglycol - pharmacology | Animals | Analysis of Variance | Phosphinic Acids - pharmacology | Benzoxazines - pharmacology | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology | Adenosine - metabolism | Picrotoxin - pharmacology | Presynaptic Terminals - metabolism | Glutamic Acid - metabolism | Mice | Receptor, Cannabinoid, CB1 - deficiency | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | In Vitro Techniques | Propanolamines - pharmacology | Neural Inhibition - drug effects
Journal Article
Psychopharmacology, ISSN 0033-3158, 12/2012, Volume 224, Issue 3, pp. 363 - 376
Pupillometry can be used to characterize autonomic drug effects.This study was conducted to determine the autonomic effects of... 
Pupil | Neurosciences | Biomedicine | Serotonin | Pupillometry | Pupillary reflex | Norepinephrine | Pharmacology/Toxicology | Psychiatry | MDMA | YOHIMBINE | PSYCHIATRY | 3,4-METHYLENEDIOXYMETHAMPHETAMINE ECSTASY | PHARMACODYNAMICS | CLINICAL PHARMACOKINETICS | NEUROSCIENCES | ALPHA-ADRENOCEPTOR | FLUCTUATIONS | AGONIST CLONIDINE | PAROXETINE | PHARMACOLOGY & PHARMACY | MYDRIASIS | Doxazosin - pharmacology | Autonomic Agents - pharmacokinetics | Humans | Mydriasis - physiopathology | Mydriatics - blood | Miosis - physiopathology | Adrenergic Agonists - pharmacology | Autonomic Agents - pharmacology | Male | N-Methyl-3,4-methylenedioxyamphetamine - blood | Adrenergic alpha-2 Receptor Agonists - pharmacology | Recovery of Function | Mydriatics - pharmacology | Young Adult | N-Methyl-3,4-methylenedioxyamphetamine - pharmacology | Time Factors | Light | Reaction Time - drug effects | Adult | Body Temperature Regulation - drug effects | Clonidine - pharmacology | Female | Mydriatics - pharmacokinetics | Autonomic Agents - blood | Affect - drug effects | Reflex, Pupillary - drug effects | Dopamine Uptake Inhibitors - pharmacology | Miosis - prevention & control | Morpholines - pharmacology | Thiophenes - pharmacology | Randomized Controlled Trials as Topic | Cross-Over Studies | Mydriasis - chemically induced | Duloxetine Hydrochloride | Adrenergic Uptake Inhibitors - pharmacology | Hemodynamics - drug effects | Carbazoles - pharmacology | Propanolamines - pharmacology | Serotonin Uptake Inhibitors - pharmacology | N-Methyl-3,4-methylenedioxyamphetamine - pharmacokinetics | Side effects | Pharmacology | Eyes & eyesight | Index Medicus | Drug abuse | Sympathomimetics | Drug tolerance | clonidine | Duloxetine | Light effects | Parasympathetic nervous system | Reflexes | reboxetine
Journal Article
Nature Neuroscience, ISSN 1097-6256, 03/2005, Volume 8, Issue 3, pp. 354 - 364
Microcircuits composed of principal neuron and interneuron dendrites have an important role in shaping the representation of sensory information in the... 
CALCIUM-CHANNELS | NMDA RECEPTORS | MEMBRANE-POTENTIALS | GABA RELEASE | MITRAL CELLS | DENDRODENDRITIC INHIBITION | GRANULE CELLS | PERIGLOMERULAR CELLS | NEUROSCIENCES | CA1 PYRAMIDAL NEURONS | SYNAPTIC ORGANIZATION | Calcium - metabolism | gamma-Aminobutyric Acid - metabolism | Membrane Potentials - radiation effects | Drug Interactions | Time Factors | Synaptic Transmission - drug effects | Neural Conduction - drug effects | Tetrodotoxin - pharmacology | Nickel - pharmacology | Olfactory Bulb - cytology | Animals, Newborn | Membrane Potentials - drug effects | Dendrites - drug effects | Calcium - pharmacology | Cadmium - pharmacology | Rats | Neural Conduction - physiology | Bicuculline - pharmacology | Chelating Agents - pharmacology | Pyrimidines - pharmacology | Potassium - pharmacology | Rats, Sprague-Dawley | GABA Antagonists - pharmacology | Signal Transduction - drug effects | Calcium Signaling - drug effects | Phosphinic Acids - pharmacology | Dihydropyridines - pharmacology | Neurons - radiation effects | Neural Conduction - radiation effects | Synaptic Transmission - physiology | Calcium Signaling - physiology | Neurons - cytology | Nimodipine - pharmacology | Patch-Clamp Techniques - methods | Diagnostic Imaging - methods | Dose-Response Relationship, Drug | Neural Inhibition - physiology | Neurons - physiology | Neurons - drug effects | Electric Stimulation - methods | Neural Networks (Computer) | Dendrites - metabolism | Synapses - physiology | Calcium Signaling - radiation effects | Valine - analogs & derivatives | 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester - pharmacology | Calcium Channel Blockers - pharmacology | Membrane Potentials - physiology | Dendrites - radiation effects | Animals | Egtazic Acid - pharmacology | Synaptic Transmission - radiation effects | Calcium Channel Agonists - pharmacology | Signal Transduction - physiology | Valine - pharmacology | In Vitro Techniques | Propanolamines - pharmacology | Neural Inhibition - drug effects | Physiological aspects | Olfactory bulb | Cellular signal transduction | Neural circuitry | Research
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 04/2011, Volume 31, Issue 14, pp. 5235 - 5243
R-type calcium channels in postsynaptic spines signal through functional calcium microdomains to regulate a calcium/calmodulin-sensitive potassium channel that... 
DENDRITIC SPINES | TRANSMITTER RELEASE | MUTANT MICE | I ADENYLYL-CYCLASE | CA2+ CHANNELS | EXCITATORY SYNAPSES | CEREBELLAR SYNAPSE | MAMMALIAN BRAIN SLICE | SYNAPTIC PLASTICITY | NEUROSCIENCES | GRANULE CELL | Neural Pathways - drug effects | Calcium - metabolism | Membrane Microdomains - metabolism | Adenosine A1 Receptor Antagonists - pharmacology | Spider Venoms - pharmacology | Xanthines - pharmacology | Neural Pathways - physiology | Patch-Clamp Techniques - methods | Purkinje Cells - physiology | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | omega-Conotoxin GVIA - pharmacology | Long-Term Potentiation - drug effects | Piperidines - pharmacology | Purkinje Cells - cytology | omega-Agatoxin IVA - pharmacology | Long-Term Potentiation - physiology | Tetrodotoxin - pharmacology | Nickel - pharmacology | Electric Stimulation - methods | Pyrazoles - pharmacology | Animals, Newborn | Presynaptic Terminals - drug effects | Rats | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Presynaptic Terminals - physiology | Calcium Channel Blockers - pharmacology | Rats, Sprague-Dawley | GABA Antagonists - pharmacology | Animals | Analysis of Variance | Calcium Signaling - drug effects | Membrane Microdomains - drug effects | Phosphinic Acids - pharmacology | Cerebellum - cytology | In Vitro Techniques | Propanolamines - pharmacology | Calcium Channels, R-Type - metabolism
Journal Article
Learning and Memory, ISSN 1072-0502, 04/2010, Volume 17, Issue 4, pp. 168 - 175
Journal Article
Biological Psychiatry, ISSN 0006-3223, 2010, Volume 67, Issue 9, pp. 831 - 839
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2012, Volume 32, Issue 12, pp. 4017 - 4031
Severe head trauma causes widespread neuronal shear injuries and acute seizures. Shearing of neural processes might contribute to seizures by disrupting the... 
GRAMICIDIN-PERFORATED-PATCH | K-CL COTRANSPORTER | INTRACELLULAR CHLORIDE | NEONATAL-RAT HIPPOCAMPUS | TEMPORAL-LOBE EPILEPSY | CATION-CHLORIDE COTRANSPORTERS | IN-VITRO ISCHEMIA | ELECTROGRAPHIC SEIZURES | EXCITATORY ACTIONS | NEUROSCIENCES | GIANT DEPOLARIZING POTENTIALS | Choline - metabolism | Age Factors | Sodium Potassium Chloride Symporter Inhibitors - pharmacology | Cell Count | Humans | Male | Nerve Net - drug effects | Recombinant Fusion Proteins - metabolism | Caspases - metabolism | Time Factors | Statistics, Nonparametric | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Female | Neurons - metabolism | Imaging, Three-Dimensional | Neurons - drug effects | Hippocampus - growth & development | Action Potentials - drug effects | Luminescent Proteins | Animals, Newborn | Valine - analogs & derivatives | Antigens, Surface - genetics | Rats | gamma-Aminobutyric Acid - pharmacology | Mice, Transgenic | Excitatory Amino Acid Antagonists - pharmacology | Hippocampus - pathology | Nerve Net - pathology | Rats, Sprague-Dawley | Bumetanide - pharmacology | GABA Antagonists - pharmacology | Membrane Glycoproteins - genetics | Action Potentials - physiology | Hippocampus - metabolism | Microscopy, Confocal | Regression Analysis | Animals | Signal Transduction - drug effects | Thioglycolates - pharmacology | Phosphinic Acids - pharmacology | Signal Transduction - physiology | Mice | Thiazoles - pharmacology | Valine - pharmacology | In Vitro Techniques | Propanolamines - pharmacology | Brain Injuries - pathology
Journal Article
Cardiovascular Research, ISSN 0008-6363, 06/2007, Volume 74, Issue 3, pp. 406 - 415
Objectives: Canine atrial cardiomyocytes display a constitutively active, acetylcholine-regulated, time-dependent K current (I ) that contributes to atrial... 
Second-messengers | Signal transduction | Ion-channels | PROTEIN-KINASE-C | CARDIAC & CARDIOVASCULAR SYSTEMS | PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE | signal transduction | RECTIFYING K+ CHANNELS | FORM STABLE COMPLEXES | VENTRICULAR MYOCYTES | GUINEA-PIG | second-messengers | SIGNALING COMPLEX | TRANSIENT OUTWARD CURRENT | ion-channels | ADENYLYL-CYCLASE | XENOPUS-OOCYTES | Maleimides - pharmacology | Adrenergic alpha-Antagonists - pharmacology | Phorbol 12,13-Dibutyrate - pharmacology | Type C Phospholipases - antagonists & inhibitors | Dose-Response Relationship, Drug | Propranolol - pharmacology | Isoquinolines - pharmacology | Phenylephrine - pharmacology | Prazosin - pharmacology | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Clonidine - pharmacology | Indoles - pharmacology | Receptors, Adrenergic, beta-1 - drug effects | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Action Potentials - drug effects | Acetylcholine - pharmacology | Heart Atria | Receptors, Adrenergic, alpha-1 - drug effects | Bee Venoms - pharmacology | Imidazoles - pharmacology | Protein Kinase C - antagonists & inhibitors | Potassium Channels - drug effects | Sulfonamides - pharmacology | Adrenergic Agents - pharmacology | Piperazines - pharmacology | Clonidine - analogs & derivatives | Patch-Clamp Techniques | Animals | Myocytes, Cardiac - drug effects | Isoproterenol - pharmacology | Dogs | Dihydropyridines - pharmacology | Myocytes, Cardiac - metabolism | Adrenergic alpha-Agonists - pharmacology | Propanolamines - pharmacology | Heart cells
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 11/2013, Volume 38, Issue 12, pp. 2484 - 2497
Activation of kappa-opioid receptors (KORs) in monoamine circuits results in dysphoria-like behaviors and stress-induced reinstatement of drug seeking in both... 
norepinephrine | kappa-opioid receptor | cocaine | reinstatement | locus coeruleus | b-adrenergic receptors | AGONIST SALVINORIN | PRESYNAPTIC INHIBITION | PSYCHIATRY | P38 MAPK | NEUROSCIENCES | BED NUCLEUS | PREFRONTAL CORTEX | CORTICOTROPIN-RELEASING-FACTOR | STRIA TERMINALIS | STRESS-INDUCED REINSTATEMENT | AXON TERMINALS | beta-adrenergic receptors | PHARMACOLOGY & PHARMACY | SALVINORIN-A | Naltrexone - analogs & derivatives | Adrenergic beta-1 Receptor Antagonists - pharmacology | Locus Coeruleus - drug effects | Male | Adrenergic alpha-2 Receptor Agonists - pharmacology | Adrenergic beta-Antagonists - pharmacology | Drug-Seeking Behavior | Naltrexone - pharmacology | Propranolol - pharmacology | Clonidine - pharmacology | Receptors, Adrenergic, beta - metabolism | Receptors, Adrenergic, alpha - metabolism | Receptors, Opioid, kappa - antagonists & inhibitors | Conditioning (Psychology) - drug effects | Mice, Inbred C57BL | Receptors, Opioid, kappa - agonists | Receptors, Opioid, kappa - metabolism | 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer - pharmacology | Cocaine - administration & dosage | Cocaine - pharmacology | Animals | Mice | Betaxolol - pharmacology | Propanolamines - pharmacology | Locus Coeruleus - metabolism | Adrenergic receptors | beta adrenergic receptors | kappa opioid receptor | Catecholamines | Neuropharmacology | behavioral Science | Original | β-adrenergic receptors | opioids
Journal Article
Journal of Neurophysiology, ISSN 0022-3077, 12/2005, Volume 94, Issue 6, pp. 4281 - 4289
Long-term depression (LTD) of the parallel fiber-Purkinje cell synapse in the cerebellum is a cellular model system that has been suggested to underlie certain... 
PURKINJE NEURONS | AMPA-RECEPTOR | PHYSIOLOGY | RAT CEREBELLUM | D-ASPARTATE RECEPTORS | NITRIC-OXIDE | METABOTROPIC GLUTAMATE RECEPTORS | NO SYNTHASE | PRESYNAPTIC NMDA | NEUROSCIENCES | CELL SYNAPSE | SYNAPTIC DEPRESSION | Electric Stimulation | 2-Amino-5-phosphonovalerate - pharmacology | Cerebellum - physiology | Purkinje Cells - physiology | N-Methylaspartate - pharmacology | Drug Interactions | Nerve Fibers - physiology | Long-Term Potentiation - drug effects | Time Factors | Long-Term Potentiation - physiology | Cadmium Chloride - pharmacology | Purkinje Cells - radiation effects | Animals, Newborn | Baclofen - pharmacology | Nerve Tissue Proteins - physiology | Synapses - physiology | Enzyme Inhibitors - pharmacology | Nerve Tissue Proteins - radiation effects | Rats | Excitatory Amino Acid Antagonists - pharmacology | Imidazoles - pharmacology | Magnesium - pharmacology | Long-Term Potentiation - radiation effects | Nerve Tissue Proteins - drug effects | Rats, Sprague-Dawley | Receptors, N-Methyl-D-Aspartate - physiology | GABA Antagonists - pharmacology | Nitroarginine - pharmacology | Animals | Phosphinic Acids - pharmacology | Cerebellum - cytology | GABA Agonists - pharmacology | Benzoates - pharmacology | Models, Neurological | In Vitro Techniques | Nitric Oxide - metabolism | Propanolamines - pharmacology | Dose-Response Relationship, Radiation
Journal Article
Journal Article
Cardiovascular Research, ISSN 0008-6363, 02/2006, Volume 69, Issue 3, pp. 736 - 745
Journal Article