X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (1209) 1209
animals (1204) 1204
index medicus (1094) 1094
apoptosis (1079) 1079
propidium iodide (885) 885
flow cytometry (733) 733
propidium - metabolism (661) 661
propidium (591) 591
apoptosis - drug effects (495) 495
cell biology (491) 491
mice (482) 482
biochemistry & molecular biology (441) 441
rats (418) 418
male (376) 376
cell line, tumor (352) 352
cells, cultured (341) 341
time factors (336) 336
cell death (331) 331
cell survival - drug effects (289) 289
expression (284) 284
proteins (274) 274
iodides (271) 271
neurosciences (266) 266
research article (260) 260
analysis (259) 259
cell cycle (256) 256
annexin v (254) 254
microbiology (254) 254
dose-response relationship, drug (250) 250
female (249) 249
oncology (249) 249
cancer (247) 247
annexin a5 - metabolism (246) 246
oxidative stress (242) 242
cell survival (236) 236
cells (232) 232
medicine (232) 232
in-vitro (230) 230
fluorescence (226) 226
cell line (223) 223
activation (221) 221
propidium - pharmacology (221) 221
flow cytometry - methods (204) 204
viability (203) 203
research (201) 201
death (194) 194
dna (189) 189
necrosis (188) 188
inhibition (186) 186
cytotoxicity (185) 185
mitochondria (185) 185
multidisciplinary sciences (183) 183
science (173) 173
blotting, western (172) 172
pharmacology & pharmacy (172) 172
fluorescent dyes (168) 168
caspase (167) 167
caspases - metabolism (164) 164
coloring agents (164) 164
cell death - drug effects (163) 163
microscopy, fluorescence (159) 159
gene expression (157) 157
cell proliferation - drug effects (156) 156
reactive oxygen species - metabolism (156) 156
biochemical research methods (153) 153
signal transduction (153) 153
toxicity (153) 153
cell proliferation (152) 152
biophysics (150) 150
staining and labeling (148) 148
biotechnology & applied microbiology (145) 145
biology (143) 143
cell membrane - metabolism (143) 143
rats, sprague-dawley (141) 141
bacteria (140) 140
immunology (137) 137
physiological aspects (134) 134
dna fragmentation (133) 133
polymerase chain reaction (132) 132
caspase-3 (131) 131
kinases (131) 131
phosphorylation (131) 131
propidium - chemistry (130) 130
medicine, research & experimental (128) 128
studies (127) 127
dna - metabolism (126) 126
immunohistochemistry (124) 124
mitochondria - metabolism (122) 122
metabolism (121) 121
proliferation (121) 121
biochemistry (120) 120
cell-death (118) 118
kinetics (118) 118
reactive oxygen species (117) 117
deoxyribonucleic acid--dna (116) 116
fluorescent dyes - metabolism (116) 116
health aspects (116) 116
toxicology (114) 114
biotechnology (113) 113
tumor cells, cultured (113) 113
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e91308
Background/Aims: An increase of ethanol metabolism and hepatic mitochondrial respiration occurs in vivo after a single binge of alcohol. Here, our aim was to... 
OXIDATIVE STRESS | REACTIVE OXYGEN | SWIFT INCREASE | PERMEABILITY TRANSITION INHIBITOR | ACETALDEHYDE ADDUCTS | MULTIDISCIPLINARY SCIENCES | ALCOHOLIC LIVER-DISEASE | PERFUSED-RAT-LIVER | N-METHYL-4-ISOLEUCINE CYCLOSPORINE | STIMULATES GLYCOGENOLYSIS | INDUCED FAT ACCUMULATION | Alcohol Dehydrogenase - metabolism | Ethanol - metabolism | Fatty Liver - metabolism | Oxidative Stress | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Mitochondria, Liver - metabolism | Liver - metabolism | Cytochrome P-450 Enzyme System - metabolism | Male | Hepatocytes - metabolism | Permeability | Hypoxia - metabolism | Mice, Knockout | Dose-Response Relationship, Drug | Mitochondria, Liver - drug effects | Ethanol - pharmacology | Animals | Liver - drug effects | Cation Transport Proteins - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Adenosine Triphosphate - metabolism | Cation Transport Proteins - genetics | Mice | Intracellular Membranes - metabolism | Alcohol, Denatured | Pyridine | Cell death | Cytochrome P-450 | Physiological aspects | Alcohol | Nucleotides | Acetaldehyde | Cytochrome | Rhodamine | Polarization | Phosphorylation | Dehydrogenases | Liver | Fluorescence | Propidium iodide | Activation | Alcohol dehydrogenase | Confocal | Kinases | Dehydrogenase | Aldehyde dehydrogenase | Depolarization | Mitochondria | Fatty liver | Metabolites | Rodents | Gastroenterology | Pyridine nucleotides | Calcein | Pyridines | Liver diseases | Ethanol | Iodides | Histology | Metabolism | Steatosis | DNA nucleotidylexotransferase | NAD | Microscopy | Hepatocytes | In vivo methods and tests | Electron transport | Respiration | Cancer | Apoptosis
Journal Article
Nature Neuroscience, ISSN 1097-6256, 09/2005, Volume 8, Issue 9, pp. 1169 - 1178
Bag1 is a cochaperone for the heat-shock protein Hsp70 that interacts with C-Raf, B-Raf, Akt, Bcl-2, steroid hormone receptors and other proteins. Here we use... 
CHAPERONE ACTIVITY | KINASE RAF-1 | BCL-2 | BCL-2-BINDING PROTEIN | HSP70 | PHOSPHORYLATION | DEATH | APOPTOTIC PROTEIN BAG-1 | NF-KAPPA-B | NEUROSCIENCES | SENSORY NEURONS | Blotting, Southern - methods | Embryo, Mammalian | Homeodomain Proteins - metabolism | Alkaline Phosphatase - metabolism | Electron Transport Complex IV - metabolism | RNA, Messenger - biosynthesis | Membrane Proteins - physiology | Hematopoietic Stem Cells - physiology | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins B-raf - metabolism | Repressor Proteins - metabolism | DNA-Binding Proteins | Fibroblasts - metabolism | Blotting, Western - methods | Motor Neurons - physiology | Immunoprecipitation - methods | Paired Box Transcription Factors | Liver - metabolism | Rats | In Situ Nick-End Labeling - methods | Mice, Knockout | Immunohistochemistry - methods | Propidium | Analysis of Variance | Eye Proteins - metabolism | Liver - cytology | Mice | Transcription Factors | Mutation | Neurofilament Proteins - metabolism | bcl-Associated Death Protein | RNA, Small Interfering - metabolism | Nestin | Spinal Cord - metabolism | Spinal Cord - growth & development | Liver - growth & development | Membrane Proteins - deficiency | Transfection - methods | Isoenzymes - metabolism | HSP70 Heat-Shock Proteins - deficiency | Reverse Transcriptase Polymerase Chain Reaction - methods | Spinal Cord - cytology | Cell Differentiation - physiology | Cell Survival - physiology | Proto-Oncogene Proteins - metabolism | Cells, Cultured | PAX6 Transcription Factor | Nerve Tissue Proteins - metabolism | Proto-Oncogene Proteins c-akt | Animals | Carrier Proteins - metabolism | Cell Count - methods | Intermediate Filament Proteins - metabolism | Physiological aspects | Research | Binding proteins | Neurons | Hematopoietic stem cells
Journal Article
Journal Article
Plant, Cell & Environment, ISSN 0140-7791, 04/2013, Volume 36, Issue 4, pp. 844 - 855
Journal Article
Neoplasia, ISSN 1476-5586, 07/2005, Volume 7, Issue 7, pp. 646 - 657
In this study, we have evaluated the cytotoxic effect of combining two HDAC inhibitors, SAHA and TSA, with TRAIL in human multiple myeloma cell lines. Low... 
apoptosis | multiple myeloma | TRAIL/Apo-2L | histone deacetylase inhibitor | death receptors | Histone deacetylase inhibitor | TRAIL/Apo-2l | Death receptors | Multiple myeloma | Apoptosis | SERINE-PROTEASE OMI/HTRA2 | HUMAN LEUKEMIA-CELLS | SUBEROYLANILIDE HYDROXAMIC ACID | LIGAND-INDUCED APOPTOSIS | ADENOCARCINOMA CELLS | FACTOR-KAPPA-B | MEDIATED APOPTOSIS | INDUCE APOPTOSIS | BREAST-CANCER CELLS | ONCOLOGY | HISTONE DEACETYLASE INHIBITORS | Tumor Necrosis Factor-alpha - metabolism | Up-Regulation | Phosphorylation | Calpain - metabolism | Cell Proliferation | Luciferases - metabolism | Membrane Glycoproteins - metabolism | Annexin A5 - pharmacology | Humans | Gene Expression Regulation, Neoplastic | E2F Transcription Factors | Immunoblotting | NF-kappa B - metabolism | Ribonucleases - metabolism | DNA-Binding Proteins - metabolism | Dose-Response Relationship, Drug | Caspases - metabolism | Flow Cytometry | TNF-Related Apoptosis-Inducing Ligand | Time Factors | Amino Acid Chloromethyl Ketones - pharmacology | Inhibitory Concentration 50 | Propidium - pharmacology | Tumor Suppressor Proteins - metabolism | Down-Regulation | Cell Cycle Proteins - metabolism | Enzyme Inhibitors - pharmacology | Mitochondria - metabolism | Mitochondria - pathology | Multiple Myeloma - metabolism | Subcellular Fractions - metabolism | Cyclin-Dependent Kinase Inhibitor p27 | Transcription Factors - metabolism | Leupeptins - pharmacology | G1 Phase | Multiple Myeloma - pathology | Apoptosis Regulatory Proteins | Membrane Potentials | Cell Line, Tumor | Protein Binding | Histone Deacetylase Inhibitors | Histones - metabolism | Cell Cycle - drug effects | Microscopy, Fluorescence | TRAIL | Apo-2L
Journal Article
Chemical Research in Toxicology, ISSN 0893-228X, 01/2011, Volume 24, Issue 1, pp. 20 - 29
Journal Article
Cell Death and Disease, ISSN 2041-4889, 02/2018, Volume 9, Issue 2, pp. 171 - 12
Journal Article
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 09/2016, Volume 116, pp. 130 - 139
The P2X7 receptor (P2X7R) plays an important role in diverse conditions associated with tissue damage and inflammation, meaning that the human P2X7R (hP2X7R)... 
YO-PRO-1 dye uptake | Virtual screening | hP2X7R antagonists | Patch-clamp recording | Ca2+ imaging | imaging | ACTIVATION | RAT | EFFICACY | SAFETY | DOCKING | CELL-DEATH | P2X RECEPTOR | CHEMISTRY | PHARMACOLOGY & PHARMACY | INHIBITORS | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Purinergic P2X Receptor Antagonists - pharmacology | Thiophenes - metabolism | Structure-Activity Relationship | Hepatocytes - metabolism | Receptors, Purinergic P2X3 - genetics | Receptors, Purinergic P2X7 - genetics | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Adenosine Triphosphate - pharmacology | Hepatocytes - cytology | Indoles - metabolism | Adenosine Triphosphate - metabolism | HEK293 Cells | Amides - metabolism | Indoles - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Single-Cell Analysis | Binding Sites | Hepatocytes - drug effects | Amides - pharmacology | Recombinant Proteins - metabolism | Models, Molecular | Rats | Recombinant Proteins - chemistry | Thiophenes - pharmacology | Adenosine Triphosphate - analogs & derivatives | Patch-Clamp Techniques | Animals | Receptors, Purinergic P2X3 - chemistry | Image Processing, Computer-Assisted | Calcium Signaling - drug effects | Purinergic P2X Receptor Antagonists - chemistry | Receptors, Purinergic P2X3 - metabolism | Small Molecule Libraries | Receptors, Purinergic P2X4 - chemistry | Amides - chemistry | Purinergic P2X Receptor Antagonists - metabolism | Receptors, Purinergic P2X7 - metabolism | Ligands | Receptors, Purinergic P2X7 - chemistry | Adenosine Triphosphate - chemistry | Receptors, Purinergic P2X4 - metabolism | Thiophenes - chemistry | Indoles - chemistry | Microscopy, Fluorescence | Receptors, Purinergic P2X4 - genetics | PI, propidium iodide | zfP2X4R, zebrafish P2X4 receptor | HEK293 cells, human embryonic kidney 293 cells | TNP-ATP, trinitrophenyl-ATP | BzATP, 2,3-O-(4-benzoylbenzoyl)-ATP | BBG, brilliant blue G | rP2X7R, rat P2X7R | P2X7R, P2X7 receptor | hP2X7R, human P2X7R
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, p. e103349
Journal Article