X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (1074) 1074
animals (989) 989
apoptosis (971) 971
index medicus (859) 859
propidium iodide (766) 766
flow cytometry (605) 605
apoptosis - drug effects (563) 563
propidium (553) 553
mice (405) 405
cell biology (366) 366
propidium - metabolism (366) 366
rats (362) 362
cell line, tumor (349) 349
biochemistry & molecular biology (336) 336
cell survival - drug effects (326) 326
cells, cultured (321) 321
propidium - pharmacology (318) 318
male (310) 310
cell death (287) 287
time factors (286) 286
iodides (285) 285
pharmacology & pharmacy (275) 275
dose-response relationship, drug (263) 263
cancer (260) 260
cytotoxicity (235) 235
expression (235) 235
analysis (232) 232
cell cycle (229) 229
in-vitro (229) 229
neurosciences (229) 229
annexin v (228) 228
oncology (217) 217
proteins (217) 217
activation (208) 208
oxidative stress (207) 207
female (200) 200
research article (196) 196
inhibition (192) 192
cell proliferation - drug effects (181) 181
microbiology (181) 181
cell line (176) 176
cell death - drug effects (175) 175
toxicity (175) 175
coloring agents (174) 174
medicine (172) 172
cells (171) 171
necrosis (170) 170
annexin a5 - metabolism (169) 169
mitochondria (168) 168
viability (168) 168
death (167) 167
fluorescence (155) 155
caspase (154) 154
blotting, western (149) 149
dna (147) 147
antineoplastic agents - pharmacology (146) 146
multidisciplinary sciences (143) 143
cell survival (142) 142
research (140) 140
fluorescent dyes (139) 139
cell cycle - drug effects (136) 136
toxicology (136) 136
caspases - metabolism (135) 135
flow cytometry - methods (134) 134
reactive oxygen species - metabolism (133) 133
enzyme inhibitors - pharmacology (131) 131
science (131) 131
signal transduction (126) 126
neurons - drug effects (124) 124
dna fragmentation (122) 122
microscopy, fluorescence (121) 121
immunology (120) 120
caspase-3 (119) 119
biochemical research methods (116) 116
rats, sprague-dawley (115) 115
cell proliferation (114) 114
proliferation (109) 109
kinases (107) 107
tumor cells, cultured (107) 107
propidium - chemistry (106) 106
cell membrane - drug effects (105) 105
cell-death (105) 105
phosphorylation (105) 105
biophysics (104) 104
rats, wistar (103) 103
biology (102) 102
in vitro techniques (102) 102
medicine, research & experimental (102) 102
gene expression (101) 101
kinetics (101) 101
mitochondria - drug effects (99) 99
reactive oxygen species (99) 99
polymerase chain reaction (98) 98
deoxyribonucleic acid--dna (96) 96
biochemistry (95) 95
growth (95) 95
staining and labeling (93) 93
chemotherapy (92) 92
health aspects (92) 92
bacteria (91) 91
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e58129
Journal Article
Inflammation Research, ISSN 1023-3830, 7/2005, Volume 54, Issue 7, pp. 273 - 280
Background: The mechanism by which low dose methotrexate (MTX) exerts its anti-inflammatory and immunosuppressive effect in rheumatoid arthritis (RA) patients... 
Allergology | Rheumatoid arthritis (RA) | Neurology | Reactive oxygen species(ROS) | Methotrexate (MTX) | Biomedicine | Immunology | Dermatology | Rheumatology | Leukocytes | Pharmacology/Toxicology | Apoptosis | Reactive oxygen species (ROS) | RHEUMATOID-ARTHRITIS | OXIDATIVE STRESS | FOLATE-DEFICIENCY | STRESS-INDUCED APOPTOSIS | apoptosis | rheumatoid arthritis (RA) | FLUORESCENCE HYPERPOLARIZATION | reactive oxygen species (ROS) | IMMUNOLOGY | ADENOSINE RELEASE | FACTOR-ALPHA | CELL BIOLOGY | TUMOR-NECROSIS-FACTOR | methotrexate (MTX) | leukocytes | HYDROGEN-PEROXIDE | SUPEROXIDE-DISMUTASE | Methotrexate - pharmacology | Cell Proliferation | Immunosuppressive Agents | Reactive Oxygen Species | Oxidative Stress | Annexin A5 - pharmacology | Humans | Antimetabolites, Antineoplastic - administration & dosage | Time Factors | T-Lymphocytes - drug effects | U937 Cells | Monocytes - pathology | Antimetabolites, Antineoplastic - pharmacology | Biological Assay | Fluorescent Dyes - pharmacology | T-Lymphocytes - pathology | Propidium - pharmacology | Fluorescein-5-isothiocyanate - pharmacology | Anti-Inflammatory Agents - pharmacology | Cell Survival | Jurkat Cells | Enzyme Inhibitors - pharmacology | Tetrazolium Salts - pharmacology | Antioxidants - pharmacology | Arthritis, Rheumatoid | Monocytes - drug effects | Acetylcysteine - pharmacology | Cell Line, Tumor | Methotrexate - administration & dosage | Thiazoles - pharmacology | Leukocytes - metabolism | Methotrexate | Dosage and administration
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2006, Volume 26, Issue 11, pp. 2956 - 2963
Excitotoxicity is generally studied in dissociated neurons, cultured hippocampal slices, or intact animals. However, the requirements of dissociated neurons or... 
NR2B | Development | Calpain | Excitotoxicity | Hippocampus | NR2A | HIPPOCAMPAL SLICES | development | hippocampus | CENTRAL NERVOUS-SYSTEM | CRITICAL PERIOD | KAINIC ACID | NEUROSCIENCES | CELL-DEATH | ADULT-RAT BRAIN | calpain | CALPAIN-MEDIATED DEGRADATION | POSTNATAL-DEVELOPMENT | ION CHANNELS | excitotoxicity | METHYL-D-ASPARTATE | Disks Large Homolog 4 Protein | Neurons - pathology | Oxygen - pharmacology | Protein Subunits | Age Factors | Propidium - analysis | Fluorescent Dyes - analysis | Intracellular Signaling Peptides and Proteins - metabolism | Hippocampus - drug effects | Receptors, N-Methyl-D-Aspartate - genetics | Quinoxalines - pharmacology | Calpain - physiology | Piperidines - pharmacology | Gene Expression Regulation, Developmental | L-Lactate Dehydrogenase - analysis | Membrane Proteins - metabolism | Spectrin - metabolism | Neurons - drug effects | Phenols - pharmacology | Receptors, N-Methyl-D-Aspartate - drug effects | Neurons - chemistry | Dipeptides - pharmacology | Valine - analogs & derivatives | Rats | Excitatory Amino Acid Antagonists - pharmacology | Glucose - pharmacology | Hippocampus - pathology | Rats, Sprague-Dawley | Animals | Biomarkers | Receptors, N-Methyl-D-Aspartate - biosynthesis | Enzyme Activation | Valine - pharmacology | Dizocilpine Maleate - pharmacology | In Vitro Techniques | Calpain - antagonists & inhibitors | N-Methylaspartate - toxicity
Journal Article
Toxicology, ISSN 0300-483X, 2009, Volume 258, Issue 2, pp. 148 - 156
Journal Article
Journal Article
Brain Research, ISSN 0006-8993, 2015, Volume 1639, pp. 214 - 227
Abstract Currently available treatment approaches for Parkinson׳s disease (PD) are limited in terms of variety and efficacy. Piper longum L. (PLL; Piperaceae)... 
Neurology | Parkinson׳s disease | Mitochondrial permeability transition pore | Treatment | CANCER-CELLS | RUTHENIUM RED | APOPTOSIS | OXIDATIVE STRESS | Parkinson's disease | RAT-LIVER MITOCHONDRIA | NEUROSCIENCES | MITOCHONDRIAL PERMEABILITY TRANSITION | PROPIDIUM IODIDE | Mitochondrial permeability | transition pore | NEUROBLASTOMA SH-SY5Y CELLS | CYTOCHROME-C RELEASE | PARKINSONS-DISEASE | Neurons - pathology | Antiparkinson Agents - pharmacology | Rats, Wistar | Apoptosis - drug effects | Plant Extracts - pharmacology | Humans | Male | Autophagy - physiology | Autophagy - drug effects | Brain - metabolism | Neuroprotective Agents - pharmacology | Dioxolanes - pharmacology | Piperidines - pharmacology | Parkinsonian Disorders - drug therapy | Neurons - metabolism | Phytotherapy | Drug Evaluation, Preclinical | Neurons - drug effects | Cell Line | Parkinsonian Disorders - physiopathology | Mitochondrial Membrane Transport Proteins - metabolism | Alkaloids - pharmacology | Mitochondrial Membrane Transport Proteins - drug effects | Random Allocation | Rotenone | Brain - drug effects | Animals | Parkinsonian Disorders - pathology | Polyunsaturated Alkamides - pharmacology | Brain - pathology | Mice | Apoptosis - physiology | Piper | Benzodioxoles - pharmacology | Antioxidants | Alkaloids | Nervous system diseases | Neurons | Analysis | Permeability | Neurophysiology
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 06/2013, Volume 68, Issue 6, pp. 1285 - 1296
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2008, Volume 3, Issue 10, pp. e3508 - e3508
Background: Glyoxalases (Glo1 and Glo2) are involved in the glycolytic pathway by detoxifying the reactive methylglyoxal (MGO) into D-lactate in a two-step... 
MULTIDISCIPLINARY SCIENCES | L-Lactate Dehydrogenase - metabolism | Cell Survival - drug effects | Anti-Inflammatory Agents - pharmacology | Humans | Cells, Cultured | Curcumin - pharmacology | Enzyme Inhibitors - pharmacology | Blood Cells - metabolism | Substrate Specificity | Interleukin-1beta - metabolism | Models, Biological | Lipopolysaccharides - pharmacology | Polyphenols | Lactoylglutathione Lyase - antagonists & inhibitors | Cell Proliferation - drug effects | Flavonoids - pharmacology | Antineoplastic Agents, Phytogenic - pharmacology | Drug Evaluation, Preclinical | Neoplasms - pathology | Blood Cells - drug effects | Phenols - pharmacology | Enzymes | Cytokines | Anti-inflammatory drugs | Analysis | Enzyme kinetics | Prostate cancer | Tumors | Brain | Propidium iodide | Biochemistry | Blood | Lipopolysaccharides | Anticancer properties | Proteins | Antitumor agents | Enzymatic activity | Gangrene | Inhibition | Iodides | Cultures | Hepatocytes | Kinetics | Pyruvaldehyde | Cell proliferation | Flow cytometry | Carcinogenic agents | Kinases | Interleukin 6 | Carcinogens | Biological effects | Immunology | Rodents | Reaction kinetics | Tumor necrosis factor-TNF | Curcumin | Astrocytoma | Interleukin 8 | Age | Glutathione | Tumor cells | Kaempferol | Blood cells | Breast cancer | Pharmacology | Inflammation | Tumor cell lines | Chemical compounds | Glycolysis | Annexin V | Lactic acid | ATP | Prostate | Apoptosis | Cancer | Index Medicus
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2010, Volume 53, Issue 13, pp. 4927 - 4937
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 09/2016, Volume 116, pp. 130 - 139
The P2X7 receptor (P2X7R) plays an important role in diverse conditions associated with tissue damage and inflammation, meaning that the human P2X7R (hP2X7R)... 
YO-PRO-1 dye uptake | Virtual screening | hP2X7R antagonists | Patch-clamp recording | Ca2+ imaging | imaging | ACTIVATION | RAT | EFFICACY | SAFETY | DOCKING | CELL-DEATH | P2X RECEPTOR | CHEMISTRY | PHARMACOLOGY & PHARMACY | INHIBITORS | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Purinergic P2X Receptor Antagonists - pharmacology | Thiophenes - metabolism | Structure-Activity Relationship | Hepatocytes - metabolism | Receptors, Purinergic P2X3 - genetics | Receptors, Purinergic P2X7 - genetics | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Adenosine Triphosphate - pharmacology | Hepatocytes - cytology | Indoles - metabolism | Adenosine Triphosphate - metabolism | HEK293 Cells | Amides - metabolism | Indoles - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Single-Cell Analysis | Binding Sites | Hepatocytes - drug effects | Amides - pharmacology | Recombinant Proteins - metabolism | Models, Molecular | Rats | Recombinant Proteins - chemistry | Thiophenes - pharmacology | Adenosine Triphosphate - analogs & derivatives | Patch-Clamp Techniques | Animals | Receptors, Purinergic P2X3 - chemistry | Image Processing, Computer-Assisted | Calcium Signaling - drug effects | Purinergic P2X Receptor Antagonists - chemistry | Receptors, Purinergic P2X3 - metabolism | Small Molecule Libraries | Receptors, Purinergic P2X4 - chemistry | Amides - chemistry | Purinergic P2X Receptor Antagonists - metabolism | Receptors, Purinergic P2X7 - metabolism | Ligands | Receptors, Purinergic P2X7 - chemistry | Adenosine Triphosphate - chemistry | Receptors, Purinergic P2X4 - metabolism | Thiophenes - chemistry | Indoles - chemistry | Microscopy, Fluorescence | Receptors, Purinergic P2X4 - genetics | PI, propidium iodide | zfP2X4R, zebrafish P2X4 receptor | HEK293 cells, human embryonic kidney 293 cells | TNP-ATP, trinitrophenyl-ATP | BzATP, 2,3-O-(4-benzoylbenzoyl)-ATP | BBG, brilliant blue G | rP2X7R, rat P2X7R | P2X7R, P2X7 receptor | hP2X7R, human P2X7R
Journal Article
Neuroscience Letters, ISSN 0304-3940, 2006, Volume 393, Issue 2, pp. 136 - 140
Journal Article