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Psychopharmacology, ISSN 0033-3158, 8/2015, Volume 232, Issue 15, pp. 2647 - 2657
Journal Article
FASEB Journal, ISSN 0892-6638, 03/2017, Volume 31, Issue 3, pp. 1193 - 1203
VEGF inhibitors, including receptor tyrosine kinase inhibitors, are used as adjunct therapies in a number of cancer treatments. An emerging issue with these... 
Hypertension | Cancer therapy | Regional hemodynamics | RTKI | VEGF | SIGNALING PATHWAY INHIBITORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TOXICITY | CANCER | RENAL-CELL CARCINOMA | BLOOD-PRESSURE | CELL BIOLOGY | cancer therapy | GROWTH-FACTOR RECEPTOR | INDUCED HYPERTENSION | TARGETED THERAPIES | regional hemodynamics | BIOLOGY | SUNITINIB | hypertension | FACTOR VEGF RECEPTORS | Niacinamide - analogs & derivatives | Male | Angiotensin II Type 1 Receptor Blockers - pharmacology | Adrenergic beta-Antagonists - pharmacology | Propranolol - pharmacology | Regional Blood Flow - drug effects | Piperidines - pharmacology | Propranolol - administration & dosage | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Quinazolines - administration & dosage | Adrenergic beta-Antagonists - administration & dosage | Angiotensin II Type 1 Receptor Blockers - administration & dosage | Piperidines - administration & dosage | Consciousness | Pyrimidines - administration & dosage | Losartan - pharmacology | Rats | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Rats, Sprague-Dawley | Niacinamide - administration & dosage | Protein Kinase Inhibitors - administration & dosage | Animals | Phenylurea Compounds - administration & dosage | Hemodynamics - drug effects | Phenylurea Compounds - pharmacology | Protein Kinase Inhibitors - pharmacology | Losartan - administration & dosage | Niacinamide - pharmacology | Quinazolines - pharmacology | Sulfonamides - administration & dosage | Drugs | Physiological effects | Drug development | Arteries | Rodents | Aorta | Protein-tyrosine kinase receptors | Blood pressure | Propranolol | Vascular endothelial growth factor | Protein-tyrosine kinase | Tyrosine | Jugular vein | Kidneys | Regional analysis | Catheters | Inhibitors | Coronary vessels | Phentolamine | Hemodynamics | Circulatory system | Cancer | Peritoneum | Research
Journal Article
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2015, Volume 372, Issue 8, pp. 735 - 746
Journal Article
Cephalalgia, ISSN 0333-1024, 7/2018, Volume 38, Issue 8, pp. 1471 - 1484
Background Nitric oxide (NO) has been heavily implicated in migraine. Nitroglycerin is a prototypic NO-donor, and triggers migraine in humans. However,... 
cGMP | nitric oxide | Trigeminovascular pain | mouse model | CGRP | OXIDATIVE STRESS | GENE-RELATED PEPTIDE | C-FOS | NITRIC-OXIDE SYNTHASE | MITOCHONDRIAL ALDEHYDE DEHYDROGENASE | CORTICAL SPREADING DEPRESSION | FOS EXPRESSION | GLYCERYL TRINITRATE INFUSION | NEUROSCIENCES | CLINICAL NEUROLOGY | EXPERIMENTAL-MODEL | HEADACHE | Hyperalgesia - chemically induced | Oxadiazoles - administration & dosage | Soluble Guanylyl Cyclase - metabolism | Allosteric Regulation | Propranolol - therapeutic use | Sumatriptan - therapeutic use | Proto-Oncogene Proteins c-fos - biosynthesis | Sumatriptan - administration & dosage | Topiramate - therapeutic use | Anticonvulsants - administration & dosage | Male | Nitric Oxide - adverse effects | Molecular Targeted Therapy | Nitroglycerin - pharmacology | Enzyme Inhibitors - administration & dosage | Migraine Disorders - chemically induced | Migraine Disorders - enzymology | Propranolol - administration & dosage | Female | Nitric Oxide Donors - pharmacology | Adrenergic beta-Antagonists - administration & dosage | Adrenergic beta-Antagonists - therapeutic use | Disease Models, Animal | Quinoxalines - therapeutic use | Topiramate - administration & dosage | Enzyme Inhibitors - metabolism | Quinoxalines - administration & dosage | Mice, Inbred C57BL | Anticonvulsants - therapeutic use | Quinoxalines - metabolism | Soluble Guanylyl Cyclase - physiology | Serotonin 5-HT1 Receptor Agonists - therapeutic use | Enzyme Inhibitors - therapeutic use | Migraine Disorders - drug therapy | Oxadiazoles - therapeutic use | Animals | Hyperalgesia - drug therapy | Migraine Disorders - etiology | Calcitonin Gene-Related Peptide - biosynthesis | Serotonin 5-HT1 Receptor Agonists - administration & dosage | Mice | Nitric Oxide - metabolism | Hyperalgesia - enzymology | Oxadiazoles - metabolism | trigeminovascular pain
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 10/2000, Volume 36, Issue 4, pp. 1233 - 1238
OBJECTIVES The goal of this study was to investigate the mechanism of reduced vasoconstrictor sensitivity to norepinephrine in women compared with men.... 
MENSTRUAL-CYCLE | NOREPINEPHRINE SPILLOVER | MEDIATED RELAXATION | SMOOTH-MUSCLE | HEART-DISEASE | CARDIAC & CARDIOVASCULAR SYSTEMS | CANINE CORONARY-ARTERIES | ENDOTHELIAL-CELLS | NITRIC-OXIDE | PERIMENOPAUSAL WOMEN | SEX-DIFFERENCES | Humans | Nitric Oxide Synthase - antagonists & inhibitors | Norepinephrine - administration & dosage | Male | Reference Values | Receptors, Adrenergic, beta-2 - drug effects | Verapamil - administration & dosage | Vascular Resistance - physiology | Enzyme Inhibitors - administration & dosage | Adrenergic alpha-Agonists - administration & dosage | Propranolol - administration & dosage | Adrenergic beta-Agonists - administration & dosage | Albuterol - administration & dosage | Forearm - blood supply | Vascular Resistance - drug effects | Adult | Female | Brachial Artery - drug effects | Adrenergic beta-Antagonists - administration & dosage | Nitroprusside - administration & dosage | Sex Characteristics | omega-N-Methylarginine - administration & dosage | Vasodilation - drug effects | Vasodilator Agents - administration & dosage | Plethysmography | Blood Flow Velocity - drug effects | Brachial Artery - physiology | Injections, Intra-Arterial | Substance P - administration & dosage | Propranolol hydrochloride | Dilatation | Analysis | Vasodilators | Nitric oxide | Sympathomimetic agents | Blood vessels | Noradrenaline
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2010, Volume 184, Issue 5, pp. 2449 - 2457
Journal Article
Journal of Gastroenterology and Hepatology, ISSN 0815-9319, 05/2016, Volume 31, Issue 5, pp. 1037 - 1044
Background and Aims: AG490, the specific inhibitor of JAK2/STAT3 signaling, has been shown to decrease portal pressure, splanchnic hyperdynamic circulation and... 
AG490 | portal hypertension | JAK2/STAT3 signaling | cirrhosis | propranolol | Cirrhosis | Propranolol | Portal hypertension | FIBROSIS | KINASE | STAT3 signaling | PATHOPHYSIOLOGY | LIVER-CIRRHOSIS | PRESSURE | INHIBITION | SIGNALING PATHWAY | BACTERIAL-INFECTION | JAK2 | BETA-BLOCKERS | GASTROENTEROLOGY & HEPATOLOGY | ENDOTHELIAL GROWTH-FACTOR | Intestines - drug effects | Antihypertensive Agents - pharmacology | Phosphorylation | Hypertension, Portal - physiopathology | Membrane Glycoproteins - metabolism | Neovascularization, Pathologic | Male | Intestines - metabolism | Spleen - drug effects | Bacterial Translocation - drug effects | Portal Pressure - drug effects | Adrenergic beta-Antagonists - pharmacology | Propranolol - pharmacology | Hypertension, Portal - etiology | Ligation | Liver - drug effects | Common Bile Duct - surgery | Drug Therapy, Combination | Interleukin-6 - metabolism | STAT3 Transcription Factor - metabolism | Disease Models, Animal | Liver Cirrhosis, Biliary - physiopathology | Splanchnic Circulation - drug effects | Acute-Phase Proteins - metabolism | Liver - metabolism | Tyrphostins - pharmacology | Rats, Sprague-Dawley | Hypertension, Portal - drug therapy | Animals | Carrier Proteins - metabolism | Spleen - metabolism | Hypertension, Portal - metabolism | Protein Kinase Inhibitors - pharmacology | Liver Cirrhosis, Biliary - complications | Liver Cirrhosis, Biliary - metabolism | Hypertension | Propranolol hydrochloride | Liver cirrhosis | Liver | Enzyme-linked immunosorbent assay | Protein binding
Journal Article