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Hypertension (Dallas, Tex. 1979), ISSN 0194-911X, 07/2015, Volume 66, Issue 1, pp. 149 - 157
prostaglandin D2 synthase 21kDa, brain | spironolactone | aldosterone | obesity | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Intramolecular Oxidoreductases - biosynthesis | Lipocalins - biosynthesis | Metabolic Syndrome - etiology | Receptors, Mineralocorticoid - genetics | Up-Regulation | Intra-Abdominal Fat - physiopathology | Humans | Male | Metabolic Syndrome - drug therapy | Obesity - genetics | Receptors, Mineralocorticoid - biosynthesis | Receptors, Mineralocorticoid - physiology | RNA, Messenger - biosynthesis | Subcutaneous Fat - metabolism | Spironolactone - pharmacology | Piperidines - pharmacology | Lipocalins - genetics | Metabolic Syndrome - physiopathology | Mineralocorticoid Receptor Antagonists - pharmacology | Enzyme Induction - drug effects | Dibenzocycloheptenes - pharmacology | Spironolactone - therapeutic use | RNA, Messenger - genetics | Insulin Resistance | Aldosterone - pharmacology | Mice, Transgenic | Obesity - physiopathology | 3T3-L1 Cells | Intra-Abdominal Fat - metabolism | Mineralocorticoid Receptor Antagonists - therapeutic use | Receptors, Leptin - deficiency | Animals | Intramolecular Oxidoreductases - genetics | Cell Line, Tumor | Mice, Obese | Adipocytes, White | Mice | Intra-Abdominal Fat - pathology | Index Medicus | Life Sciences
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 04/2014, Volume 133, Issue 4, pp. 1184 - 1194.e7
Group 2 innate lymphoid cell | PGD2 | chemoattractant receptor-homologous molecule expressed on TH2 cells | adaptive type 2 immunity | IL-25 | IL-33 | innate type 2 immunity | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Immunopathology | Biological and medical sciences | Medical sciences | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Mast Cells - immunology | Lymphocyte Subsets - drug effects | Humans | Immunophenotyping | Receptors, Prostaglandin - metabolism | Lymphocyte Subsets - immunology | Dose-Response Relationship, Drug | Gene Expression Regulation - drug effects | Lymphocyte Subsets - metabolism | Lymphocyte Activation - immunology | Phenotype | Receptors, Prostaglandin - genetics | Lymphocyte Activation - drug effects | Mast Cells - metabolism | Prostaglandin D2 - pharmacology | Chemotaxis - immunology | Receptors, Immunologic - genetics | Cytokines - biosynthesis | Receptors, Immunologic - metabolism | Index Medicus | Abridged Index Medicus | CRTH2, Chemoattractant receptor-homologous molecule expressed on TH2 cells | PGD2, Prostaglandin D2 | cysLT, Cysteinyl leukotriene | CSF-1, Macrophage colony-stimulating factor | CysLT1, Cysteinyl leukotriene receptor 1 | EC50, Median effective concentration | ILC2, Group 2 innate lymphoid cell | ILC, Innate lymphoid cell | Mechanisms of Allergy and Clinical Immunology | Medicin och hälsovetenskap
Journal Article
Journal of medicinal chemistry, ISSN 0022-2623, 02/2007, Volume 50, Issue 4, pp. 794 - 806
Biological and medical sciences | Medical sciences | Histamine and antagonists. Allergy | Pharmacology. Drug treatments | Microsomes - metabolism | Nasal Decongestants - pharmacokinetics | Stereoisomerism | Humans | Nasal Decongestants - chemical synthesis | Indoles - chemical synthesis | Macaca fascicularis | Bile - metabolism | Male | Structure-Activity Relationship | Hepatocytes - metabolism | Receptors, Immunologic - antagonists & inhibitors | Indoles - pharmacology | Receptors, Prostaglandin - antagonists & inhibitors | Binding, Competitive | Nasal Decongestants - pharmacology | Rats | Rats, Sprague-Dawley | Animals | Dogs | Protein Binding | Indoles - pharmacokinetics | Sheep | Mice | Airway Obstruction - drug therapy | In Vitro Techniques | Index Medicus
Journal Article
Pain (Amsterdam), ISSN 0304-3959, 05/2011, Volume 152, Issue 5, pp. 1114 - 1126
Excitability | CRTH2 | Sensory neuron | DP2 receptor | Sodium channel | DP1 receptor | Neurology | Analgesics | Pharmacology. Drug treatments | Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction | Biological and medical sciences | Medical sciences | Neuropharmacology | Nervous system (semeiology, syndromes) | Membrane Potentials - drug effects | Prostaglandin D2 - antagonists & inhibitors | Hydantoins - pharmacology | Rats, Wistar | Cells, Cultured | Rats | Male | Sodium Channel Blockers - pharmacology | Ganglia, Spinal - cytology | Sulfonamides - pharmacology | Receptors, Prostaglandin - metabolism | Dose-Response Relationship, Drug | Patch-Clamp Techniques | Animals | Sensory Receptor Cells - drug effects | Platelet Aggregation Inhibitors - pharmacology | Prostaglandin D2 - pharmacology | Tetrodotoxin - pharmacology | Carbazoles - pharmacology | Action Potentials - drug effects | Receptors, Immunologic - metabolism | Ganglia, Spinal - metabolism | Index Medicus
Journal Article
Hypertension (Dallas, Tex. 1979), ISSN 0194-911X, 01/2014, Volume 63, Issue 1, pp. 80 - 87
Oxidative stress | receptor | Nrf2 | Prostaglandin F | Prostaglandin D2 | PPAR gamma | 15-deoxyprostaglandin J2 | Cardiology. Vascular system | Biological and medical sciences | Arterial hypertension. Arterial hypotension | Medical sciences | Blood and lymphatic vessels | Lipocalins - metabolism | PPAR gamma - metabolism | Receptors, Prostaglandin - metabolism | Mice, Knockout | Myocardial Reperfusion Injury - metabolism | Animals | Dexamethasone - pharmacology | Prostaglandin D2 - metabolism | Myocardium - metabolism | NF-E2-Related Factor 2 - metabolism | Glucocorticoids - pharmacology | Heart - drug effects | Myocytes, Cardiac - metabolism | Prostaglandin D2 - analogs & derivatives | NF-E2-Related Factor 2 - genetics | Mice | Intramolecular Oxidoreductases - metabolism | Index Medicus
Journal Article
Respiratory research, ISSN 1465-9921, 02/2007, Volume 8, Issue 1, pp. 16 - 16
Inflammation - pathology | Bronchial Hyperreactivity - immunology | Receptors, Immunologic - antagonists & inhibitors | Inflammation - drug therapy | Bronchial Hyperreactivity - physiopathology | Sensitivity and Specificity | Asthma - immunology | Female | Prostaglandin Antagonists - pharmacology | Bronchoalveolar Lavage Fluid - cytology | Radioligand Assay | Receptors, Prostaglandin - antagonists & inhibitors | Disease Models, Animal | Pulmonary Eosinophilia - immunology | Immunization | Enzyme-Linked Immunosorbent Assay | Cells, Cultured | Sulfonamides - pharmacology | Asthma - drug therapy | Pulmonary Eosinophilia - pathology | Animals | Mice | Mice, Inbred BALB C | Carbazoles - pharmacology | In Vitro Techniques | Asthma - pathology | Allergens | Prostaglandins | Inflammation | Histochemistry | Asthma | Index Medicus | Research | Disease Models | Inflammation: pathology | Inbred BALB C | Medical and Health Sciences | Prostaglandin Antagonists: pharmacology | Medicin och hälsovetenskap | Pulmonary Eosinophilia: immunology | Klinisk medicin | Asthma: drug therapy | Receptors | Pulmonary Eosinophilia: pathology | Cultured | Lungmedicin och allergi | Asthma: immunology | Bronchoalveolar Lavage Fluid: cytology | Bronchial Hyperreactivity: immunology | Respiratory Medicine and Allergy | Immunologic: antagonists & inhibitors | Prostaglandin: antagonists & inhibitors | Sulfonamides: pharmacology | Cells | Inflammation: drug therapy | Clinical Medicine | Carbazoles: pharmacology | Bronchial Hyperreactivity: physiopathology | Animal | Asthma: pathology
Journal Article
Clinical pharmacology and therapeutics, ISSN 0009-9236, 06/2007, Volume 81, Issue 6, pp. 849 - 857
Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Humans | Middle Aged | Male | Regional Blood Flow | Indoles - administration & dosage | Receptors, Immunologic - antagonists & inhibitors | Cross-Over Studies | Dose-Response Relationship, Drug | Niacin - administration & dosage | Skin - blood supply | Indoles - adverse effects | Adolescent | Niacin - adverse effects | Adult | Female | Indoles - therapeutic use | Aspirin - pharmacology | Vasodilation - drug effects | Vasodilator Agents - adverse effects | Delayed-Action Preparations | Receptors, Prostaglandin - antagonists & inhibitors | Vasodilator Agents - administration & dosage | Index Medicus | Abridged Index Medicus
Journal Article
Journal of investigative dermatology, ISSN 0022-202X, 12/2006, Volume 126, Issue 12, pp. 2637 - 2646
Dermatology | Biological and medical sciences | Medical sciences | Receptors, Nicotinic - metabolism | Oligonucleotide Array Sequence Analysis | Receptors, G-Protein-Coupled - metabolism | Skin - metabolism | Humans | Mice, Inbred C57BL | Cells, Cultured | Male | Hypolipidemic Agents - pharmacology | RNA, Messenger - metabolism | Niacin - pharmacology | Tissue Distribution | Animals | Prostaglandin D2 - metabolism | Mice | Receptors, G-Protein-Coupled - genetics | Flushing - chemically induced | In Vitro Techniques | Langerhans Cells - drug effects | Langerhans Cells - metabolism | Receptors, Nicotinic - genetics | Index Medicus
Journal Article
Nature reviews. Drug discovery, ISSN 1474-1776, 04/2007, Volume 6, Issue 4, pp. 313 - 325
Animals | Hypersensitivity - metabolism | Hypersensitivity - physiopathology | Prostaglandin D2 - metabolism | Humans | Prostaglandin Antagonists - pharmacology | Asthma - drug therapy | Hypersensitivity - drug therapy | Receptors, Prostaglandin - antagonists & inhibitors | Receptors, Immunologic - antagonists & inhibitors | Prostaglandins | Regulation | Immune response | Research | Analysis | Central nervous system | Index Medicus
Journal Article
Journal of ethnopharmacology, ISSN 0378-8741, 12/2015, Volume 175, pp. 470 - 480
Traditional Chinese medicines | Docking | Androgenic alopecia | Hair loss | Prostaglandin D2 synthase | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Integrative & Complementary Medicine | Plant Sciences | Science & Technology | Dermatologic Agents - toxicity | Humans | Drugs, Chinese Herbal - pharmacology | Intramolecular Oxidoreductases - antagonists & inhibitors | Dermatologic Agents - therapeutic use | Cyclooxygenase Inhibitors - toxicity | Lipocalins - antagonists & inhibitors | Computer Simulation | Drugs, Chinese Herbal - therapeutic use | Quantitative Structure-Activity Relationship | Dermatologic Agents - pharmacology | Medicine, Chinese Traditional | Skin Absorption | Cyclooxygenase Inhibitors - chemistry | Cyclooxygenase Inhibitors - pharmacology | Dermatologic Agents - chemistry | Drugs, Chinese Herbal - toxicity | Animals | Drugs, Chinese Herbal - chemistry | Models, Biological | Alopecia - drug therapy | ROC Curve | Molecular Docking Simulation | Cyclooxygenase Inhibitors - therapeutic use | Skin - drug effects | Baldness | Prostaglandins | Alopecia | Index Medicus
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 05/2015, Volume 135, Issue 5, pp. 1358 - 1366.e11
leukotriene E4 | TH2 cells | Prostaglandin D2 | chemoattractant receptor-homologous molecule expressed on TH2 cells | neutrophils | leukotriene E | Prostaglandin D | chemoattractant receptor-homologous molecule expressed on T | 2 cells | Leukotriene E4 - metabolism | Cell Communication - immunology | Cell Adhesion Molecules - genetics | Apoptosis - drug effects | Humans | Gene Expression Profiling | Th2 Cells - immunology | Th2 Cells - drug effects | Leukotriene E4 - pharmacology | Chemotaxis, Leukocyte - genetics | Chemotaxis, Leukocyte - drug effects | Prostaglandin D2 - metabolism | Inflammation Mediators - metabolism | Neutrophils - metabolism | Gene Expression | Neutrophils - drug effects | Neutrophils - immunology | Cell Communication - genetics | Cell Adhesion Molecules - metabolism | Th2 Cells - metabolism | Drug Synergism | Apoptosis - immunology | Cell Communication - drug effects | Prostaglandin D2 - pharmacology | Chemotaxis, Leukocyte - immunology | Cluster Analysis | Index Medicus | Abridged Index Medicus | LTE4, Cysteinyl leukotriene E4 | CysLT2, Cysteinyl leukotriene receptor 2 | CRTH2, Chemoattractant receptor-homologous molecule expressed on TH2 cells | PMA, Phorbol 12-myristate 13-acetate | LTC4, Cysteinyl leukotriene C4 | PGD2, Prostaglandin D2 | CAIA, Cell activation–induced aggregation | cysLT, Cysteinyl leukotriene | qPCR, Quantitative PCR | PI3K, Phosphoinositide 3-kinase | LTD4, Cysteinyl leukotriene D4 | CysLT1, Cysteinyl leukotriene receptor 1 | ICAM, Intercellular adhesion molecule | RORγt, Retinoic acid–related orphan receptor γt | Mechanisms of Allergy and Clinical Immunology
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 137, Issue 3, pp. 833 - 843
Allergy and Immunology | macrophages | prostaglandin D2 | hematopoietic prostaglandin D synthase | pulmonary inflammation | D-type prostanoid receptor 2/chemoattractant receptor–homologous molecule expressed on TH2 cells | D-type prostanoid receptor 1 | neutrophils | D-type prostanoid receptor 2/chemoattractant receptor-homologous molecule expressed on T | 2 cells | prostaglandin D | Respiratory Distress Syndrome, Adult - pathology | Lung Injury - pathology | Humans | Respiratory Distress Syndrome, Adult - metabolism | Receptors, Prostaglandin - metabolism | Lung Injury - etiology | Respiratory Distress Syndrome, Adult - etiology | Receptors, Prostaglandin - genetics | Inflammation Mediators - metabolism | Lung Injury - metabolism | Lung - metabolism | Neutrophils - metabolism | Calcium Signaling | Macrophages - immunology | Neutrophil Infiltration - immunology | Gene Expression | Lung - pathology | Neutrophils - drug effects | Neutrophils - immunology | Macrophages - metabolism | Animals | Endotoxins - immunology | Macrophages - drug effects | Mice | Prostaglandin D2 - pharmacology | Chemotaxis, Leukocyte - immunology | Receptors, Immunologic - genetics | Tumor Necrosis Factor-alpha - biosynthesis | Cytokines - biosynthesis | Lung - immunology | Receptors, Immunologic - metabolism | Endotoxins - adverse effects | Index Medicus | Abridged Index Medicus | D-type prostanoid receptor 2 | chemoattractant receptor–homologous molecule expressed on TH2 cells | Medicin och hälsovetenskap
Journal Article