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Science, ISSN 0036-8075, 03/2016, Volume 351, Issue 6279, pp. 1333 - 1338
Journal Article
STEM CELLS, ISSN 1066-5099, 10/2012, Volume 30, Issue 10, pp. 2283 - 2296
Culturing cells in three dimension (3D) provides an insight into their characteristics in vivo. We previously reported that human mesenchymal stem/stromal... 
Sphere | Caspase | COX2 | MSC | LPS | Macrophage | PROTEIN TSG-6 | STEM-CELLS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | IN-VITRO | MSCS | BACTERIAL CLEARANCE | ONCOLOGY | HUMAN BONE-MARROW | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | INFLAMMATION | ENDOTHELIAL-CELLS | TNF-ALPHA | HEMATOLOGY | MARROW STROMAL CELLS | Mannose-Binding Lectins - metabolism | RNA, Small Interfering - genetics | Humans | NF-kappa B - metabolism | Spheroids, Cellular - cytology | Lectins, C-Type - genetics | Lectins, C-Type - metabolism | Dinoprostone - isolation & purification | Mesenchymal Stromal Cells - cytology | Caspases - metabolism | Cyclooxygenase 2 - genetics | Spheroids, Cellular - drug effects | Cell Culture Techniques | Fibroblasts - metabolism | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Receptors, Prostaglandin E, EP4 Subtype - genetics | Dinoprostone - pharmacology | Mesenchymal Stromal Cells - drug effects | Cyclooxygenase 2 Inhibitors - pharmacology | Caspases - genetics | Spheroids, Cellular - metabolism | Mesenchymal Stromal Cells - metabolism | Receptors, Cell Surface - metabolism | Antibodies - pharmacology | Gene Expression Regulation - drug effects | Culture Media, Conditioned | Macrophages - metabolism | Mannose-Binding Lectins - genetics | NF-kappa B - genetics | Signal Transduction - drug effects | Fibroblasts - drug effects | Cyclooxygenase 2 - metabolism | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Dinoprostone - antagonists & inhibitors | Macrophage Activation - drug effects | Cytokines - biosynthesis | Receptors, Cell Surface - genetics | Anti-inflammatory drugs | RNA | Analysis | Prostaglandins E | Stem cells | Genetic aspects | Information management | Macrophages | Cytokines | Genotype & phenotype | Molecular weight | Index Medicus | Antibodies | macrophage | spheroid | caspase
Journal Article
Journal of Immunology, ISSN 0022-1767, 05/2017, Volume 198, Issue 9, pp. 3558 - 3564
PGE2 has been shown to increase the transcription of pro–IL-1β. However, recently it has been demonstrated that PGE2 can block the maturation of IL-1β by... 
Protein kinase A | Transcription | Prostaglandin E2 | Blocking | Septic shock | Feedback loops | Tumor necrosis factor-α | Positive feedback | Macrophages | Kinases | IL-1β | Fever | Lipopolysaccharides | Monocytes | Feedback | Bone marrow | Indomethacin | Inhibition | ATP | Index Medicus | Abridged Index Medicus
Journal Article
European Journal of Immunology, ISSN 0014-2980, 05/2009, Volume 39, Issue 5, pp. 1301 - 1312
The contribution of Th1 and Th17 cells in chronic inflammatory conditions leading to autoimmunity remains highly controversial. In inflamed tissues, production... 
Memory T cells | IFN-γ | Prostaglandin | Th17 | IL-17 | RHEUMATOID-ARTHRITIS | COLLAGEN-INDUCED ARTHRITIS | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | IMMUNOLOGY | JOINT INFLAMMATION | GROWTH-FACTOR-BETA | PROSTANOID RECEPTORS | INFLAMMATORY-BOWEL-DISEASE | IFN-gamma | MULTIPLE-SCLEROSIS | ROR-GAMMA | CENTRAL-NERVOUS-SYSTEM | T-Lymphocyte Subsets - immunology | Humans | Interleukin-17 - immunology | T-Box Domain Proteins - immunology | RNA, Messenger - metabolism | Th1 Cells - immunology | Dinoprostone - immunology | Receptors, Retinoic Acid - genetics | CD4-Positive T-Lymphocytes - immunology | Receptors, Prostaglandin E, EP4 Subtype | Receptors, Thyroid Hormone - genetics | Autoimmunity - immunology | T-Lymphocyte Subsets - drug effects | Receptors, Retinoic Acid - immunology | Receptors, Prostaglandin E - immunology | Interferon-gamma - genetics | Receptors, Thyroid Hormone - immunology | Immunologic Memory - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 | Dinoprostone - pharmacology | Th1 Cells - drug effects | RNA, Messenger - genetics | Interleukin-17 - genetics | Interleukin-17 - biosynthesis | Reverse Transcriptase Polymerase Chain Reaction | T-Box Domain Proteins - genetics | Interleukin-17 - antagonists & inhibitors | Interferon-gamma - immunology | Receptors, Prostaglandin E, EP2 Subtype | Autoimmunity - drug effects | CD4-Positive T-Lymphocytes - drug effects | Interferon-gamma - biosynthesis | Index Medicus
Journal Article
European Journal of Immunology, ISSN 0014-2980, 09/2015, Volume 45, Issue 9, pp. 2661 - 2671
Macrophages have important functions in tissue homeostasis, but the exact mechanisms regarding wide spectrum of macrophage phenotype remain unresolved. In this... 
Homeostasis | CREB | Prostaglandin E | Macrophages | C/EBP‐β | C/EBP-β | ACTIVATION | PHOSPHORYLATION | Prostaglandin E-2 | IL-10 PRODUCTION | RECEPTOR | E-2 | IMMUNOLOGY | BINDING PROTEIN-BETA | CYCLIC-AMP | C/EBP-beta | GENE-EXPRESSION | TISSUE MACROPHAGES | POLARIZATION | Dinoprostone - biosynthesis | Prostaglandin-Endoperoxide Synthases - immunology | Arginase - immunology | Cyclic AMP-Dependent Protein Kinases - genetics | Isoquinolines - pharmacology | Cyclic AMP Response Element-Binding Protein - immunology | Macrophage Colony-Stimulating Factor - pharmacology | Female | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Membrane Glycoproteins - immunology | Macrophages - immunology | Prostaglandin-Endoperoxide Synthases - genetics | Cell Line | Signal Transduction | Colforsin - pharmacology | CCAAT-Enhancer-Binding Protein-beta - genetics | Mice, Inbred C57BL | Gene Expression Regulation | Arginase - genetics | Macrophages - cytology | Sulfonamides - pharmacology | Receptors, Cell Surface - immunology | Indomethacin - pharmacology | Membrane Glycoproteins - genetics | Cyclic AMP Response Element-Binding Protein - genetics | Phenotype | Animals | CCAAT-Enhancer-Binding Protein-beta - immunology | Cell Differentiation - drug effects | Cyclic AMP-Dependent Protein Kinases - immunology | Interleukin-10 - genetics | Macrophages - drug effects | Mice | Primary Cell Culture | Interleukin-10 - immunology | Receptors, Cell Surface - genetics | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 06/2007, Volume 447, Issue 7147, pp. 1007 - 1011
Journal Article
Journal Article