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Prostaglandins and Other Lipid Mediators, ISSN 1098-8823, 2002, Volume 68, pp. 401 - 407
Journal Article
PROSTAGLANDINS & OTHER LIPID MEDIATORS, ISSN 1098-8823, 08/2002, Volume 68-9, pp. 401 - 407
Prostaglandin (PG) F-2 is synthesized via three pathways from PGE(2), PGD(2), or PGH(2) by PGE 9-ketoreductase, PGD 11-ketoreductase, or PGH 9-,... 
TRANSFORMATION | 9-KETOREDUCTASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | reductase PGF(2 alpha) | CARBONYL REDUCTASE | E-2 | IDENTIFICATION | CELL BIOLOGY | 9(alpha) | aldo-keta reductase family | BOVINE LUNG | LIVER | PURIFICATION | 11 beta-PGF | PGF synthase | CDNA CLONING | ACID 9-ALPHA,11-BETA-PROSTAGLANDIN-F2
Journal Article
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 2008, Volume 75, Issue 2, pp. 484 - 493
Aldo-keto reductase (AKR) 1C3 (type 2 3α-HSD, type 5 17β-HSD, and prostaglandin F synthase) regulates ligand access to steroid hormone and prostaglandin... 
Prostaglandin metabolism | Inhibitor design | Steroid hormone metabolism | Cancer treatment | NSAIDs | Chemoprevention | cancer treatment | ANDROGEN RECEPTOR | SIGNALING PATHWAYS | INCREASED EXPRESSION | CRYSTAL-STRUCTURE | prostaglandin metabolism | 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J | PROLIFERATOR-ACTIVATED RECEPTOR | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | chemoprevention | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | ACID-BINDING PROTEIN | CYCLOOXYGENASE-2 INHIBITORS | inhibitor design | PHARMACOLOGY & PHARMACY | steroid hormone metabolism | Indomethacin - analogs & derivatives | Oxidation-Reduction | Humans | Enzyme Inhibitors - pharmacology | Hydroxyprostaglandin Dehydrogenases - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Hydroxyprostaglandin Dehydrogenases - antagonists & inhibitors | Melatonin - analogs & derivatives | Aldo-Keto Reductase Family 1 Member C3 | 3-Hydroxysteroid Dehydrogenases - metabolism | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Catalysis | Neoplasms, Hormone-Dependent - drug therapy | Melatonin - pharmacology | Phenanthrenes - metabolism | Dihydrotestosterone - metabolism | Enzymes | Care and treatment | Synthetic prostaglandins F | Crystals | Hormones | Organic acids | Heterocyclic compounds | Physiological aspects | Glycols | Hormones, Sex | Indomethacin | Structure | Cancer
Journal Article
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 2009, Volume 178, Issue 1, pp. 221 - 227
Aldo-keto reductase (AKR) 1C3 catalyzes the NADPH-dependent reduction of Δ -androstene-3,17-dione to yield testosterone, reduction of estrone to yield... 
Indomethacin | Prostaglandin metabolism | Steroid hormone metabolism | N-Phenylanthranilic acids | Aldo-keto reductase | CELLS | SIGNALING PATHWAYS | ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | DEHYDROGENASE | SELECTIVE COX-2 INHIBITORS | STEROID-PRODUCING ENZYMES | PROGNOSTIC MARKER | PHARMACOLOGY & PHARMACY | TOXICOLOGY | EXPRESSION
Journal Article
Journal Article
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 2012, Volume 3, p. 98
Prostaglandins are important regulators of female reproductive functions to which aldose reductases exhibiting hydroxysteroid dehydrogenase activity also... 
Prostaglandins | Biosynthesis | Regulation | Menstrual cycle | Endometrium | endometrium | prostaglandins | PHARMACOLOGY & PHARMACY | regulation | biosynthesis | menstrual cycle | Endothelial Cells | Aldose reductase inhibitors | Human endometrium | Glucose | Prostaglandin biosynthesis | Ischemia
Journal Article
Biology of Reproduction, ISSN 0006-3363, 2014, Volume 90, Issue 5
ABSTRACT Prostaglandins (PGs) are important lipid mediators regulating various reproductive processes in many species. In pigs, the expression pattern of PGE2... 
implantation | uterus | prostaglandin | endometrium | AKR1B1 | female reproductive tract | pig
Journal Article
Journal Article
Acta Crystallographica Section F, ISSN 2053-230X, 05/2015, Volume 71, Issue 5, pp. 609 - 614
The crystal structures of prostaglandin F synthase (PGF) from both Leishmania major and Trypanosoma cruzi with and without their cofactor NADP have been... 
Chagas disease | SSGCID | leishmaniasis |