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Endocrinology, ISSN 0013-7227, 01/2018, Volume 159, Issue 1, pp. 490 - 505
Cyclooxygenase (COX)-derived prostaglandins stimulate uterine contractions and prepare the cervix for parturition. Prior reports suggest Cox-1 knockout (KO)... 
RECEPTOR-DEFICIENT MICE | F RECEPTOR | CYTOSOLIC PHOSPHOLIPASE A | MURINE PARTURITION | EMBRYO IMPLANTATION | ENDOCRINOLOGY & METABOLISM | DELAYED PARTURITION | KNOCKOUT MICE | MOUSE UTERUS | PRETERM LABOR | PROGESTERONE WITHDRAWAL | Cervical Ripening - drug effects | Luteolysis - drug effects | Myometrium - drug effects | Ovariectomy - adverse effects | Cervix Uteri - metabolism | Oxytocin - pharmacology | Abortifacient Agents, Steroidal - pharmacology | Pregnancy, Prolonged - pathology | Pregnancy, Prolonged - prevention & control | Pregnancy, Prolonged - drug therapy | Myometrium - metabolism | Cervix Uteri - pathology | Female | Membrane Proteins - metabolism | Oxytocics - therapeutic use | Cervix Uteri - drug effects | Oxytocics - pharmacology | Cyclooxygenase 1 - genetics | Abortifacient Agents, Steroidal - therapeutic use | Myometrium - pathology | Membrane Proteins - genetics | Cells, Cultured | Mice, Inbred Strains | Mice, Knockout | Uterine Contraction - drug effects | Pregnancy | Pregnancy, Prolonged - metabolism | Animals | Progesterone - metabolism | Cyclooxygenase 1 - metabolism | In Vitro Techniques | Mifepristone - pharmacology | Mifepristone - therapeutic use | Oxytocin - therapeutic use | Parturition | Surgical implants | Myometrium | Calcium (intracellular) | Calcium | Oxytocin | Ovariectomy | Contractility | Implantation | Cervix | Contraction | Prostaglandin endoperoxide synthase | Proteins | Genotype & phenotype | Prostaglandins | Cyclooxygenase-1 | Uterus | Rodents | Dilation | Mice | Progesterone | Females | Delivery contracts | Index Medicus | Abridged Index Medicus
Journal Article
Biochimie, ISSN 0300-9084, 05/2019, Volume 160, pp. 28 - 33
Osteoarthritis (OA) is one of the main locomotor disorders in horses. Although nonsteroidal anti-inflammatory drugs are the first-line treatment for OA,... 
mPGES-1 | Arthritis | PTGS2 | LPS | Opioids | APOPTOSIS | CELLS | INDUCED SYNOVITIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | E-2 | ENDOCYTOSIS | INFLAMMATION | EXPRESSION | RECEPTOR DESENSITIZATION | ANTIINFLAMMATORY DRUGS | Synthetic prostaglandins E | Morphine | Mitogens | Analysis | Index Medicus
Journal Article
Brazilian Journal of Medical and Biological Research, ISSN 0100-879X, 2018, Volume 51, Issue 2, pp. e6546 - e6546
The inducible inflammatory enzyme cycloxigenase-2 is up-regulated in cancer, and favors tumor progression. Cycloxigenase-2 is encoded by the... 
Haplotypes | COX-2 | Gene expression | PTGS2 | HEK293FT | MCF-7 | MEDICINE, RESEARCH & EXPERIMENTAL | CYCLOOXYGENASE-2 | RISK | CELL-LINES | BREAST-CANCER | POLYMORPHISMS | BIOLOGY | ASSOCIATION | Prostaglandins | Research | Index Medicus
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2004, Volume 101, Issue 30, pp. 11165 - 11169
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 03/2014, Volume 53, Issue 3, pp. 192 - 200
Because proprotein convertases (PCSKs) activate growth factors and matrix metalloproteinase, these enzymes have been implicated in non-small cell lung cancer... 
proprotein convertase | FURIN | cancer | PTGS2 | prostaglandin E2 | Prostaglandin E2 | Proprotein convertase | Cancer | TUMOR PROGRESSION | INCREASED EXPRESSION | CARCINOMA CELLS | CANCER CELLS | PACE4 | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VITRO | ONCOLOGY | MOUSE MODEL | GROWTH | GENE-EXPRESSION | PROPROTEIN CONVERTASES FURIN | RNA, Small Interfering - genetics | Cell Proliferation | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Promoter Regions, Genetic - genetics | Immunoenzyme Techniques | Furin - genetics | Cyclooxygenase 2 - genetics | E2F1 Transcription Factor - antagonists & inhibitors | Lung - metabolism | Real-Time Polymerase Chain Reaction | Furin - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Lung - pathology | Carcinoma, Non-Small-Cell Lung - genetics | Cyclooxygenase 2 - chemistry | RNA, Messenger - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Cells, Cultured | E2F1 Transcription Factor - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Cell Adhesion | Blotting, Western | Cyclooxygenase 2 - metabolism | E2F1 Transcription Factor - genetics | Apoptosis | Cell Movement | Lung cancer, Non-small cell | Development and progression | Prostaglandins | Enzymes | Protein expression | Cellular biology | Lung cancer | Index Medicus
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 09/2012, Volume 26, Issue 9, pp. 3800 - 3810
Female mice lacking group IVA phospholipase A(2) (Pla2g4a(-/-)) have a smaller litter size, which is due, in part, to defective implantation. We examined... 
FEEDBACK-CONTROL | PRIMED IMMATURE RATS | GRANULOSA-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ARACHIDONIC-ACID | HUMAN CHORIONIC-GONADOTROPIN | REDUCED FERTILITY | MICE LACKING | prostaglandin E-2 | female reproduction | CELL BIOLOGY | EICOSANOID GENERATION | BIOLOGY | GENE DISRUPTION | preovulatory follicle | CYCLOOXYGENASE-2 EXPRESSION | PLA isoforms
Journal Article