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signal transduction (249) 249
prostaglandin-endoperoxide synthases - genetics (247) 247
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isoenzymes - genetics (180) 180
oncology (180) 180
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receptors, prostaglandin e - genetics (176) 176
reverse transcriptase polymerase chain reaction (176) 176
abridged index medicus (172) 172
cytokines (172) 172
gene-expression (172) 172
cells (170) 170
receptors, prostaglandin e - metabolism (168) 168
cell line, tumor (166) 166
dinoprostone - pharmacology (162) 162
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neurosciences (157) 157
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blotting, western (149) 149
inhibition (149) 149
mitogens (148) 148
immunohistochemistry (146) 146
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activation (145) 145
dose-response relationship, drug (145) 145
nitric-oxide synthase (145) 145
endocrinology & metabolism (144) 144
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Journal Article
Animal Science Journal, ISSN 1344-3941, 11/2018, Volume 89, Issue 11, pp. 1540 - 1548
The spleen is a unique lymphoid organ that plays a key role in immune regulation. Interferon‐tau induces upregulation of interferon‐stimulated gene 15‐kDa... 
prostaglandin synthase | ISG15 | spleen | sheep | pregnancy | CELLS | AGRICULTURE, DAIRY & ANIMAL SCIENCE | PROGESTERONE | UTERUS | BONE-MARROW | TAU | RECEPTOR | MECHANISMS | MATERNAL RECOGNITION | IDENTIFICATION | Up-Regulation | Aldehyde Reductase - genetics | Spleen - immunology | Ubiquitins - genetics | Uterus - metabolism | Pregnancy, Animal - genetics | Cyclooxygenase 2 - genetics | Prostaglandin-E Synthases - genetics | Pregnancy, Animal - immunology | Aldehyde Reductase - metabolism | Female | Placentation - genetics | Sheep - genetics | Cytokines - genetics | Ubiquitins - metabolism | Cyclooxygenase 1 - genetics | Gene Expression | Cytokines - metabolism | Prostaglandin-E Synthases - metabolism | Placentation - physiology | Pregnancy | Animals | Spleen - metabolism | Cyclooxygenase 2 - metabolism | Sheep - metabolism | Cyclooxygenase 1 - metabolism | COX-2 inhibitors | Pregnant women | Prostaglandins E | Genes | Genetic research | Interferon | Biological response modifiers | Spleen | Immunohistochemistry | Estrus | Immune response | Immunoregulation | Paracrine signalling | mRNA | Estrus cycle | Gene expression | Prostaglandin endoperoxide synthase | Proteins | Immune systems | Cords | Prostaglandins | Uterus | Cyclooxygenase-1 | Sheep | Dimers | Prostaglandin E | Autocrine signalling | Reductase | Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 07/2016, Volume 134, Issue 4, pp. 328 - 338
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 02/2017, Volume 195, Issue 4, pp. 456 - 463
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2011, Volume 286, Issue 3, pp. 2331 - 2342
A major immunological response during neuroinflammation is the activation of microglia, which subsequently release proinflammatory mediators such as... 
RAT SPINAL-CORD | TUMOR-NECROSIS-FACTOR | ISCHEMIC TOLERANCE | LIGAND-BINDING | NEONATAL-RAT | E RECEPTOR SUBTYPES | MESSENGER-RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | PAIN HYPERSENSITIVITY | LIPOPOLYSACCHARIDE | INNATE IMMUNITY | Inflammation - chemically induced | Tumor Necrosis Factor-alpha - metabolism | Microglia - metabolism | Myelitis - chemically induced | Myelitis - enzymology | Tumor Necrosis Factor-alpha - genetics | Interleukin-1beta - genetics | Receptors, Prostaglandin E - genetics | Cyclooxygenase 2 - genetics | Interleukin-1beta - metabolism | Intramolecular Oxidoreductases - metabolism | Prostaglandins - genetics | Disease Models, Animal | Prostaglandin-Endoperoxide Synthases - genetics | Receptors, Epoprostenol - metabolism | Lipopolysaccharides - toxicity | Myelitis - genetics | Receptors, Thromboxane A2, Prostaglandin H2 - metabolism | Cells, Cultured | Rats | Receptors, Thromboxane A2, Prostaglandin H2 - genetics | Rats, Sprague-Dawley | Mice, Knockout | Up-Regulation - drug effects | Receptors, Epoprostenol - genetics | Animals | Intramolecular Oxidoreductases - genetics | Prostaglandin-Endoperoxide Synthases - metabolism | Prostaglandin-E Synthases | Cyclooxygenase 2 - metabolism | Inflammation - genetics | Mice | Inflammation - enzymology | Receptors, Prostaglandin E - metabolism | Prostaglandins - metabolism | Index Medicus | Prostaglandins | mPGES-1 | Immunology | Spinal Cord | Innate Immunity | Tumor Necrosis Factor (TNF) | Inflammation | Cyclooxygenase (COX) Pathway | Cyclic AMP (cAMP) | Microglia
Journal Article
Journal Article
Apoptosis, ISSN 1360-8185, 11/2017, Volume 22, Issue 11, pp. 1431 - 1440
We previously reported that microsomal prostaglandin E synthase-1 (mPGES-1) contributed to adriamycin (Adr)-induced podocyte apoptosis. However, the molecular... 
Biochemistry, general | PGE2 | mPGES-1 | Podocyte apoptosis | Biomedicine | Adriamycin | Stat3 | Cancer Research | Oncology | Cell Biology | Virology | FIBROSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INJURY | DAMAGE | CELL BIOLOGY | URSOLIC ACID | INHIBITION | INFLAMMATION | INTERSTITIAL FIBROBLAST ACTIVATION | KIDNEY | CONTRIBUTES | RNA, Small Interfering - genetics | Apoptosis - drug effects | Dinoprostone - biosynthesis | STAT3 Transcription Factor - agonists | Apoptosis - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Dose-Response Relationship, Drug | Benzenesulfonates - pharmacology | Prostaglandin-E Synthases - antagonists & inhibitors | Prostaglandin-E Synthases - genetics | Chemokine CCL2 - metabolism | Membrane Proteins - metabolism | Phosphorylation - drug effects | Interleukin-6 - metabolism | Intracellular Signaling Peptides and Proteins - genetics | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Dinoprostone - pharmacology | Aminosalicylic Acids - pharmacology | Podocytes - metabolism | Interleukin-6 - genetics | Prostaglandin-E Synthases - metabolism | Signal Transduction | Membrane Proteins - genetics | Gene Expression Regulation | Interleukin-17 - genetics | Chemokine CCL2 - genetics | Podocytes - cytology | Interleukin-17 - metabolism | Intercellular Adhesion Molecule-1 - metabolism | Animals | Podocytes - drug effects | Intercellular Adhesion Molecule-1 - genetics | Mice | STAT3 Transcription Factor - antagonists & inhibitors | Cell Line, Transformed | Doxorubicin - pharmacology | RNA, Small Interfering - metabolism | Synthetic prostaglandins E | Medical colleges | Anthracyclines | Apoptosis | Phosphorylation | Cytokines | Intercellular adhesion molecule 1 | Stat3 protein | Prostaglandin E2 | siRNA | Inflammation | Kinases | Prostaglandin-E synthase | Interleukin 17 | Interleukin 6 | Reduction | Prostaglandin E | Monocyte chemoattractant protein 1 | Index Medicus
Journal Article
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 09/2016, Volume 116, pp. 120 - 129
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 06/2017, Volume 102, Issue 6, pp. 1971 - 1982
Context: In animal models, the luteinizing hormone surge increases progesterone (P4) and progesterone receptor (PGR), prostaglandins (PTGs), and epidermal... 
HUMAN GRANULOSA-CELLS | ENDOPEROXIDE SYNTHASE-2 | MESSENGER-RIBONUCLEIC-ACID | INHIBITION | GROWTH-FACTORS | ENDOCRINOLOGY & METABOLISM | BOVINE PREOVULATORY FOLLICLES | RECEPTOR | PERIOVULATORY INTERVAL | HUMAN CHORIONIC-GONADOTROPIN | EXPRESSION | Immunohistochemistry | Humans | Gene Expression Profiling | Receptors, Progesterone - genetics | RNA, Messenger - metabolism | Organic Anion Transporters - metabolism | Chorionic Gonadotropin - pharmacology | Receptors, Progesterone - metabolism | Organic Anion Transporters - genetics | Cyclooxygenase 2 - genetics | Prostaglandin-E Synthases - genetics | Polymerase Chain Reaction | Amphiregulin - metabolism | Adult | Female | Ovarian Follicle - metabolism | Amphiregulin - genetics | Luteal Cells | Prostaglandin-E Synthases - metabolism | Cells, Cultured | Prostaglandin-E Synthases - drug effects | Epidermal Growth Factor - metabolism | Cyclooxygenase 2 - drug effects | Ovulation | Blotting, Western | Luteinizing Hormone | Fertilization in Vitro | Receptors, Progesterone - drug effects | Cyclooxygenase 2 - metabolism | Progesterone - metabolism | Granulosa Cells | Organic Anion Transporters - drug effects | Prostaglandins - metabolism | In vitro fertilization | Potentiation | Animal models | Chorionic gonadotropin | Fertilization | Genes | Lutein | Cultures | Pituitary (anterior) | Gonadotropins | mRNA | Ovaries | Follicles | Ribonucleic acid--RNA | Mimicry | Signaling | Prostaglandins | Epidermal growth factor | Granulosa cells | Luteinizing hormone | Conditioning | Progesterone | Index Medicus | Abridged Index Medicus | growth-factors | expression | messenger-ribonucleic-acid | bovine preovulatory follicles | inhibition | human chorionic-gonadotropin | periovulatory interval | synthase-2 | receptor | Endokrinologi och diabetes | human granulosa-cells | endoperoxide | Endocrinology & Metabolism | Endocrinology and Diabetes
Journal Article