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1. Full Text Exosome targeting of tumor antigens expressed by cancer vaccines can improve antigen immunogenicity and therapeutic efficacy
by Rountree, Ryan B and Mandl, Stefanie J and Nachtwey, James M and Dalpozzo, Katie and Do, Lisa and Lombardo, John R and Schoonmaker, Peter L and Brinkmann, Kay and Dirmeier, Ulrike and Laus, Reiner and Delcayre, Alain
Cancer research (Chicago, Ill.), ISSN 0008-5472, 08/2011, Volume 71, Issue 15, pp. 5235 - 5244
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Tumors | Adenocarcinoma - pathology | Humans | Male | Th1 Cells - immunology | Vaccinia virus - immunology | Drug Delivery Systems | Prostatic Neoplasms - immunology | Prostatic Neoplasms - therapy | Protein Tyrosine Phosphatases - immunology | Cancer Vaccines - therapeutic use | Milk Proteins - immunology | Exosomes - immunology | Immunotherapy, Active - methods | Antibodies, Neoplasm - biosynthesis | Milk Proteins - pharmacokinetics | Protein Structure, Tertiary | Prostate-Specific Antigen - administration & dosage | Prostatic Neoplasms - pathology | Antigens, Neoplasm - immunology | Adenocarcinoma - immunology | Cancer Vaccines - administration & dosage | Mice, Inbred C57BL | Xenograft Model Antitumor Assays | Cancer Vaccines - immunology | Vaccines, Attenuated - immunology | Animals | Adenocarcinoma - therapy | Acid Phosphatase | Mice | Mice, Inbred BALB C | Prostate-Specific Antigen - immunology | Antigens, Surface - immunology | Index Medicus
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2. Full Text Lactobacilli secreting a tumor antigen and IL15 activates neutrophils and dendritic cells and generates cytotoxic T lymphocytes against cancer cells
by Kandasamy, Matheswaran and Bay, Boon-Huat and Lee, Yuan-Kun and Mahendran, Ratha
Cellular immunology, ISSN 0008-8749, 2011, Volume 271, Issue 1, pp. 89 - 96
IL-15 | CTL | Neutrophils | PSA | Lactobacillus | DC | Immunology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Antigens, CD - immunology | Cell Proliferation | Immunoglobulins - immunology | Membrane Glycoproteins - metabolism | Dendritic Cells - immunology | Lactobacillus rhamnosus - genetics | Interleukin-15 - immunology | Antigens, CD - metabolism | Histocompatibility Antigens Class I - metabolism | Immunoglobulins - metabolism | CD40 Antigens - metabolism | T-Lymphocytes - metabolism | Urinary Bladder Neoplasms - pathology | Female | Histocompatibility Antigens Class II - metabolism | Prostate-Specific Antigen - metabolism | Membrane Glycoproteins - immunology | B7-2 Antigen - immunology | Lactobacillus rhamnosus - immunology | Neutrophils - metabolism | Dendritic Cells - metabolism | Cytokines - immunology | Prostate-Specific Antigen - genetics | T-Lymphocytes, Cytotoxic - immunology | Cytokines - metabolism | B7-1 Antigen - immunology | Mice, Inbred C57BL | Cells, Cultured | Histocompatibility Antigens Class I - immunology | Neutrophils - immunology | B7-1 Antigen - metabolism | B7-2 Antigen - metabolism | Animals | Histocompatibility Antigens Class II - immunology | Interleukin-15 - genetics | T-Lymphocytes, Cytotoxic - metabolism | Interleukin-15 - metabolism | Urinary Bladder Neoplasms - therapy | Urinary Bladder Neoplasms - immunology | Cell Line, Tumor | Lactobacillus rhamnosus - metabolism | T-Lymphocytes - immunology | Mice | Prostate-Specific Antigen - immunology | Cytotoxicity, Immunologic - immunology | CD40 Antigens - immunology | Index Medicus
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3. The application of prostate specific membrane antigen in CART-cell therapy for treatment of prostate carcinoma (Review)
by Ullah, Kifayat and Peprah, Frank Addai and Yu, Feng and Shi, Haifeng
Oncology reports, ISSN 1021-335X, 12/2018, Volume 40, Issue 6, pp. 3136 - 3143
Antigen | Chimeric antigen receptors | Prostate specific antigen | T-cell | Prostate cancer | Life Sciences & Biomedicine | Oncology | Science & Technology | Glutamate Carboxypeptidase II - immunology | Prostatic Neoplasms - pathology | Immunotherapy, Adoptive - methods | Antigens, Neoplasm - immunology | Humans | Neoplasm Invasiveness - immunology | Neoplasm Invasiveness - prevention & control | Male | Treatment Outcome | Prostatic Neoplasms - immunology | Prostatic Neoplasms - therapy | Prostate - pathology | Prostate - immunology | Receptors, Chimeric Antigen - immunology | Antigens, Surface - immunology
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4. Full Text Anti-tumor effect of the alphavirus-based virus-like particle vector expressing prostate-specific antigen in a HLA–DR transgenic mouse model of prostate cancer
by Riabov, V and Tretyakova, I and Alexander, R.B and Pushko, P and Klyushnenkova, E.N
Vaccine, ISSN 0264-410X, 2015, Volume 33, Issue 41, pp. 5386 - 5395
Allergy and Immunology | Vaccine | TC-83 virus | VLPV | Prostate cancer | DR2b mice | PSA | Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Alphavirus - immunology | Dendritic Cells - immunology | Humans | Male | Immunity | HLA-DR Antigens - genetics | Prostatic Neoplasms - immunology | Prostatic Neoplasms - therapy | Cancer Vaccines - genetics | Vaccines, Virus-Like Particle - genetics | Prostatic Neoplasms - genetics | Lymphocytes, Tumor-Infiltrating - metabolism | Gene Order | Dendritic Cells - metabolism | Disease Models, Animal | Prostate-Specific Antigen - genetics | Cell Line | Prostatic Neoplasms - pathology | Alphavirus - genetics | Gene Expression | Immunization | Mice, Transgenic | Genetic Vectors - genetics | Cancer Vaccines - immunology | Animals | Vaccines, Virus-Like Particle - immunology | HLA-DR Antigens - immunology | Mice | Prostate-Specific Antigen - immunology | Lymphocytes, Tumor-Infiltrating - immunology | Tumor Burden - immunology | Antigens | Genetic vectors | Analysis | Vaccination | Genetic engineering | Tumors | Immunohistochemistry | Dendritic cells | HLA histocompatibility antigens | Antibodies | T cells | Viral antibodies | Histocompatibility antigens | Stem cells | Adenocarcinoma | Prostate-specific antigen | CD8 antigen | Immunoglobulin G | Genes | Immune clearance | Clinical trials | Viruses | Lymphocytes T | Genomes | Histocompatibility antigen H-2 | Vaccines | Metastasis | Experiments | Cancer therapies | Virus-like particles | Anticancer properties | Metastases | Lymphocytes | Coding | Immunotherapy | Drb1 protein | Immune system | Spleen | Immune response | Tumor cells | Transgenic mice | Glycoproteins | Immunological tolerance | Immune response (humoral) | Studies | γ-Interferon | In vivo methods and tests | Infiltration | Histocompatibility antigen HLA | Prostate | Viral infections | Cancer | Index Medicus | prostate cancer | vaccine
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5. Full Text Bovine papillomavirus prostate cancer antigen virus-like particle vaccines are efficacious in advanced cancers in the TRAMP mouse spontaneous prostate cancer model
by Simons, Brian W and Cannella, Fabiana and Rowley, Dayana T and Viscidi, Raphael P
CANCER IMMUNOLOGY IMMUNOTHERAPY, ISSN 0340-7004, 04/2020, Volume 69, Issue 4, pp. 641 - 651
Oncology | Immunology | Life Sciences & Biomedicine | Science & Technology | Acid Phosphatase - immunology | GPI-Linked Proteins - immunology | Antigens, Neoplasm - immunology | Cancer Vaccines - administration & dosage | Humans | Vaccination | Neoplasm Proteins - immunology | Male | Mice, Transgenic | Treatment Outcome | Interferon-gamma - metabolism | Prostatic Neoplasms - immunology | Prostatic Neoplasms - therapy | Cancer Vaccines - immunology | Acid Phosphatase - metabolism | Animals | Interferon-gamma - immunology | CD8-Positive T-Lymphocytes - metabolism | Capsid Proteins - immunology | Vaccines, Virus-Like Particle - immunology | Prostate-Specific Antigen - immunology | Epitopes, T-Lymphocyte - immunology | CD8-Positive T-Lymphocytes - immunology | Disease Models, Animal | Adenocarcinoma | Animal models | CD8 antigen | Clinical trials | Lymphocytes T | Vaccines | Carcinogenesis | Virus-like particles | Metastases | Cancer vaccines | Lymphocytes | Immunotherapy | Antigens | Immunization | Therapeutic applications | L1 protein | CD3 antigen | Epitopes | Immune checkpoint | Antigen (tumor-associated) | γ-Interferon | Stem cells | Infiltration | Prostate cancer | Acid phosphatase | Index Medicus
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6. Full Text Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial
by Madan, Ravi A, MD and Mohebtash, Mahsa, MD and Arlen, Philip M, MD and Vergati, Matteo, MD and Rauckhorst, Myrna, RN and Steinberg, Seth M, PhD and Tsang, Kwong Y, PhD and Poole, Diane J and Parnes, Howard L, MD and Wright, John J, MD PhD and Dahut, William L, MD and Schlom, Jeffrey, PhD and Gulley, James L, Dr
The lancet oncology, ISSN 1470-2045, 2012, Volume 13, Issue 5, pp. 501 - 508
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Antigens, CD - immunology | Viral Vaccines - therapeutic use | Humans | Ipilimumab | Middle Aged | Antibodies, Monoclonal - therapeutic use | Immunotherapy, Active | Male | Antineoplastic Agents - therapeutic use | Poxviridae - immunology | Orchiectomy | Prostatic Neoplasms - immunology | Prostatic Neoplasms - therapy | Dose-Response Relationship, Drug | Cancer Vaccines - immunology | Cancer Vaccines - therapeutic use | Prostatic Neoplasms - secondary | Aged, 80 and over | Aged | Prostate-Specific Antigen - immunology | Viral Vaccines - immunology | Antigens | Care and treatment | Oncology, Experimental | Clinical trials | Vaccines | Research | Metastasis | T cells | Cancer vaccines | Monoclonal antibodies | Product development | Prostate cancer | Cancer | Protein binding | Index Medicus
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7. Full Text Functional Specialty of CD40 and Dendritic Cell Surface Lectins for Exogenous Antigen Presentation to CD8+ and CD4+ T Cells
by Yin, Wenjie and Gorvel, Laurent and Zurawski, Sandra and Li, Dapeng and Ni, Ling and Duluc, Dorothée and Upchurch, Katherine and Kim, JongRok and Gu, Chao and Ouedraogo, Richard and Wang, Zhiqing and Xue, Yaming and Joo, HyeMee and Gorvel, Jean-Pierre and Zurawski, Gerard and Oh, SangKon
EBioMedicine, ISSN 2352-3964, 03/2016, Volume 5, Issue C, pp. 46 - 58
Cross-presentation | Lectins | Dendritic cell | CD40 | Vaccine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Recombinant Fusion Proteins - immunology | Lectins - immunology | Scavenger Receptors, Class E - immunology | Dendritic Cells - immunology | Humans | Lectins, C-Type - immunology | Immunotherapy, Active | Mice, Transgenic | Antigen Presentation - immunology | CD40 Ligand - immunology | CD4-Positive T-Lymphocytes - immunology | Cell Differentiation - immunology | Lymphocyte Activation - immunology | Animals | Mice | CD8-Positive T-Lymphocytes - immunology | Index Medicus | Life Sciences | Immunology
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8. Full Text Breaking immune tolerance by targeting CD25+ regulatory T cells is essential for the anti‐tumor effect of the CTLA‐4 blockade in an HLA‐DR transgenic mouse model of prostate cancer
by Klyushnenkova, Elena N and Riabov, Vladimir B and Kouiavskaia, Diana V and Wietsma, Ashley and Zhan, Min and Alexander, Richard B
The Prostate, ISSN 0270-4137, 10/2014, Volume 74, Issue 14, pp. 1423 - 1432
regulatory T cells | CTL‐associated antigen‐4 | HLA‐DR2 transgenic mice | prostate‐specific antigen | TRAMP tumor | CTL-associated antigen-4 | HLA-DR2 transgenic mice | prostate-specific antigen | Endocrinology & Metabolism | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Antibodies, Monoclonal - pharmacology | Humans | Immune Tolerance | Male | Mice, Transgenic | Random Allocation | CTLA-4 Antigen - immunology | Prostate-Specific Antigen - blood | Prostatic Neoplasms - immunology | Prostatic Neoplasms - therapy | T-Lymphocytes, Regulatory - immunology | HLA-DR2 Antigen - immunology | Animals | Mice | Prostate-Specific Antigen - immunology | CD8-Positive T-Lymphocytes - immunology | CTLA-4 Antigen - antagonists & inhibitors | HLA-DR2 Antigen - genetics | Antibodies, Monoclonal - immunology | Disease Models, Animal | Interleukin-2 Receptor alpha Subunit - immunology | Histocompatibility antigens | Analysis | Immunotherapy | Tumor antigens | HLA histocompatibility antigens | Genetic engineering | T cells | Prostate cancer | Tumors | Index Medicus
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9. Full Text 3D label-free prostate specific antigen (PSA) immunosensor based on graphene–gold composites
by Jang, Hee Dong and Kim, Sun Kyung and Chang, Hankwon and Choi, Jeong-Woo
Biosensors & bioelectronics, ISSN 0956-5663, 01/2015, Volume 63, pp. 546 - 551
Aerosol spray pyrolysis | Crumpled graphene–gold composite | Label-free immunosensor | Prostate specific antigen (PSA) | Crumpled graphene-gold composite | Physical Sciences | Chemistry | Nanoscience & Nanotechnology | Life Sciences & Biomedicine | Electrochemistry | Science & Technology - Other Topics | Biophysics | Chemistry, Analytical | Biotechnology & Applied Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biotechnology | Biological and medical sciences | Biosensors | Methods. Procedures. Technologies | Various methods and equipments | Gold - chemistry | Immunoassay - instrumentation | Nanocomposites - chemistry | Antibodies - chemistry | Metal Nanoparticles - chemistry | Oxides - chemistry | Equipment Design | Prostate-Specific Antigen - analysis | Conductometry - instrumentation | Staining and Labeling | Antibodies - immunology | Biosensing Techniques - instrumentation | Nanocomposites - ultrastructure | Prostate-Specific Antigen - immunology | Graphite - chemistry | Prostate-Specific Antigen - chemistry | Equipment Failure Analysis | Pyrolysis | Composite materials industry | Graphene | Prostate-specific antigen | Graphite | Prostate cancer | Electric properties | Index Medicus | Electrodes | Antigens | Gold | Immunosensors | Prostate | Three dimensional
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10. Full Text Phase II study of lutetium-177-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 for metastatic castration-resistant prostate cancer
by Tagawa, Scott T and Milowsky, Matthew I and Morris, Michael and Vallabhajosula, Shankar and Christos, Paul and Akhtar, Naveed H and Osborne, Joseph and Goldsmith, Stanley J and Larson, Steve and Taskar, Neeta Pandit and Scher, Howard I and Bander, Neil H and Nanus, David M
Clinical cancer research, ISSN 1078-0432, 09/2013, Volume 19, Issue 18, pp. 5182 - 5191
Life Sciences & Biomedicine | Oncology | Science & Technology | Tumors of the urinary system | Urinary tract. Prostate gland | Gynecology. Andrology. Obstetrics | Pharmacology. Drug treatments | Nephrology. Urinary tract diseases | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Antineoplastic agents | Male genital diseases | Tumors | Glutamate Carboxypeptidase II - immunology | Prognosis | Prospective Studies | Follow-Up Studies | Glutamate Carboxypeptidase II - antagonists & inhibitors | Prostatic Neoplasms, Castration-Resistant - radiotherapy | Humans | Middle Aged | Antibodies, Monoclonal - therapeutic use | Male | Survival Rate | Prostate-Specific Antigen - blood | Prostatic Neoplasms, Castration-Resistant - secondary | Neoplasm Metastasis | Neoplasm Grading | Image Processing, Computer-Assisted | Aged, 80 and over | Aged | Prostatic Neoplasms, Castration-Resistant - mortality | Neoplasm Staging | Antigens, Surface - immunology | Index Medicus | Prostate-specific Membrane Antigen | Prostate Cancer | Monoclonal Antibody | Radioimmunotherapy
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