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Journal Article
European Urology, ISSN 0302-2838, 2014, Volume 67, Issue 1, pp. 53 - 60
Abstract Background Enzalutamide is a novel antiandrogen with proven efficacy in metastatic castration-resistant prostate cancer (mCRPC). Objective To evaluate... 
Urology | Castration-resistant prostate cancer | Primary resistance to enzalutamide | Androgen signaling inhibition | Bone metastasis | Bone tumor microenvironment | Adaptive feedback mechanism | Androgen receptor | Predictors of outcome | Enzalutamide | Tissue-based research | TESTOSTERONE | CHEMOTHERAPY | RECEPTOR SPLICE VARIANTS | THERAPY | DEPRIVATION | CLINICAL-TRIALS | UROLOGY & NEPHROLOGY | INCREASED SURVIVAL | PROGRESSION | ABIRATERONE | Prospective Studies | Phenylthiohydantoin - therapeutic use | Humans | Middle Aged | Receptors, Androgen - metabolism | Retroviridae Proteins, Oncogenic - metabolism | Bone Neoplasms - secondary | Cytoplasm - metabolism | Drug Resistance, Neoplasm | Ki-67 Antigen - metabolism | Male | Antineoplastic Agents - therapeutic use | Receptors, Glucocorticoid - metabolism | Prostatic Neoplasms, Castration-Resistant - pathology | Bone Neoplasms - metabolism | Cell Nucleus - metabolism | Protein Isoforms - metabolism | Bone Marrow - metabolism | Aged, 80 and over | Adult | Bone Neoplasms - drug therapy | Testosterone - blood | Gene Dosage | Prostatic Neoplasms, Castration-Resistant - drug therapy | Prostatic Neoplasms, Castration-Resistant - metabolism | Bone Marrow Neoplasms - secondary | Phenylthiohydantoin - analogs & derivatives | Prostate-Specific Antigen - blood | Receptors, Androgen - genetics | Signal Transduction - drug effects | Bone Marrow Neoplasms - metabolism | Aged | Bone Marrow Neoplasms - drug therapy | Steroid 17-alpha-Hydroxylase - metabolism | Prostate cancer | Metastasis | Bone marrow biopsy | Androgen | Antiandrogens
Journal Article
Journal Article
BJU International, ISSN 1464-4096, 02/2012, Volume 109, Issue 1, pp. 22 - 29
Journal Article
Chemical Communications, ISSN 1359-7345, 07/2013, Volume 49, Issue 59, pp. 6602 - 6604
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2011, Volume 286, Issue 2, pp. 1248 - 1259
GRP78, a well characterized chaperone in the endoplasmic reticulum, is critical to the unfolded protein response. More recently, it has been identified on the... 
SIGNAL-TRANSDUCTION | ANTIBODIES | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA-MACROGLOBULIN | RECEPTOR | COOH-TERMINAL DOMAIN | ALPHA-2-MACROGLOBULIN | NF-KAPPA-B | EXPRESSION | PSA | Prostatic Neoplasms - metabolism | MAP Kinase Signaling System - physiology | Ribosomal Protein S6 Kinases - metabolism | Humans | Gene Expression Regulation, Neoplastic | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Cell Movement - physiology | Heat-Shock Proteins - genetics | Up-Regulation - physiology | Prostate-Specific Antigen - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Methylamines - pharmacology | Prostate-Specific Antigen - genetics | Prostatic Neoplasms - pathology | Heat-Shock Proteins - metabolism | Prostate-Specific Antigen - secretion | MAP Kinase Kinase Kinases - metabolism | Cell Division - physiology | Up-Regulation - drug effects | alpha-Macroglobulins - metabolism | Cell Line, Tumor | Apoptosis - physiology | Feedback, Physiological - physiology | Cell Migration | Molecular Bases of Disease | GRP78 Interaction with alpha2-Macroglobulin·PSA Complexes | Protein Synthesis | PSA and Prostate Cancer Progression | Akt PKB | Regulation of Prostate Cancer Cell Proliferation | Apoptosis | DNA Synthesis | alpha2-Macroglobulin·PSA Complexes and Prostate Cancer
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2016, Volume 59, Issue 5, pp. 1761 - 1775
Journal Article
ENDOCRINOLOGY, ISSN 0013-7227, 10/2017, Volume 158, Issue 10, pp. 3540 - 3552
Adipose tissue-derived adipokines i.e., leptin/adiponectin/resistin) play important roles in the regulation of several pathophysiologic processes through the... 
LEPTIN | INSULIN | METFORMIN | OBESITY | ADIPONECTIN RECEPTORS | MOUSE | ENDOCRINOLOGY & METABOLISM | GROWTH-HORMONE AXIS | CANCER | ADIPOSE-TISSUE | Prostatic Neoplasms - metabolism | Humans | Leptin - metabolism | Receptors, Adiponectin - metabolism | Ki-67 Antigen - metabolism | Male | Prostate - metabolism | MAP Kinase Signaling System | Prostate-Specific Antigen - drug effects | Adiponectin - metabolism | Fasting - metabolism | Proto-Oncogene Proteins c-myc - drug effects | Real-Time Polymerase Chain Reaction | Cell Line | Resistin - metabolism | Prostate-Specific Antigen - secretion | Tumor Suppressor Protein p53 - metabolism | Adipokines - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Proto-Oncogene Proteins c-myc - metabolism | Tumor Suppressor Protein p53 - drug effects | Blotting, Western | Obesity - metabolism | Cell Movement - drug effects | Animals | Adipokines - pharmacology | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Receptors, Leptin - metabolism | Ki-67 Antigen - drug effects | Regulations | Animal models | Adipose tissue | Leukocyte migration | Prostate-specific antigen | p53 Protein | Glands | c-Myc protein | Homology | Activation | Myc protein | Tissues | Adiponectin | Receptors | Synthesis | Modulation | Tumorigenesis | Coordination compounds | Obesity | Fasting | Secretion | Markers | Extracellular signal-regulated kinase | Cultures | Metabolism | Signaling | Cell lines | Ligands | Prostate | Cell migration
Journal Article
Journal Article