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Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 514 - 527
Interleukin-21 (IL-21) has broad actions on T and B cells, but its actions in innate immunity are poorly understood. Here we show that IL-21 induced apoptosis... 
NKT CELLS | HOMEOSTASIS | FOLLICULAR-HELPER-CELLS | HUMAN B-CELLS | STEADY-STATE | INTERLEUKIN-21 | DIFFERENTIATION | IMMUNOLOGY | IMMUNE TOLERANCE | T-CELLS | NEGATIVE REGULATOR | Natural Killer T-Cells - drug effects | Oligonucleotide Array Sequence Analysis | Apoptosis - drug effects | Dendritic Cells - immunology | STAT5 Transcription Factor - immunology | Receptors, Interleukin-21 - genetics | Interferon-gamma - metabolism | CD4-Positive T-Lymphocytes - immunology | Interleukins - genetics | Gene Expression - immunology | STAT3 Transcription Factor - genetics | Apoptosis Regulatory Proteins - immunology | DNA-Binding Proteins - immunology | Membrane Proteins - genetics | CD4-Positive T-Lymphocytes - metabolism | Mice, Transgenic | DNA, Intergenic - genetics | Protein Binding - immunology | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Mice, Knockout | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Galactosylceramides - immunology | Mice | STAT3 Transcription Factor - immunology | Gene Expression - drug effects | Galactosylceramides - pharmacology | DNA-Binding Proteins - deficiency | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | Receptors, Interleukin-21 - deficiency | Flow Cytometry | Bcl-2-Like Protein 11 | Natural Killer T-Cells - metabolism | DNA, Intergenic - metabolism | Interleukins - immunology | Proto-Oncogene Proteins - immunology | Apoptosis Regulatory Proteins - genetics | Dendritic Cells - drug effects | Membrane Proteins - metabolism | Interleukins - pharmacology | Dendritic Cells - metabolism | STAT3 Transcription Factor - metabolism | Proto-Oncogene Proteins - metabolism | Receptors, Interleukin-21 - immunology | Mice, Inbred C57BL | Cells, Cultured | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Membrane Proteins - immunology | Proto-Oncogene Proteins - genetics | DNA-Binding Proteins - genetics | Animals | Apoptosis - immunology | Interferon-gamma - immunology | CD4-Positive T-Lymphocytes - drug effects | DNA, Intergenic - immunology | Natural Killer T-Cells - immunology | Interleukins | Dendritic cells | Analysis | Genomics | Macrophage colony stimulating factor | Biological response modifiers | T cells | Apoptosis | Cytokines | Genes | Genomes | Kinases | Binding sites | Deoxyribonucleic acid--DNA | Index Medicus | apoptosis | dendritic cells | GM-CSF | IL-21
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2011, Volume 187, Issue 1, pp. 424 - 433
Journal Article
Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 596 - 605
T follicular helper (Tfh) cells provide help to B cells and are crucial for establishment of germinal center (GC) reactions, including production of... 
CXC CHEMOKINE RECEPTOR-5 | DENDRITIC CELLS | BCL6 | ANTIBODY-PRODUCTION | IN-VIVO DEPLETION | IMMUNE-RESPONSES | DYNAMICS | GENERATION | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION | Ovalbumin - immunology | Germinal Center - immunology | Humans | CD40 Ligand - immunology | CD3 Complex - genetics | CD40 Antigens - metabolism | CD40 Ligand - metabolism | Flow Cytometry | Inducible T-Cell Co-Stimulator Ligand - metabolism | T-Lymphocytes, Helper-Inducer - immunology | Antibodies - immunology | B-Lymphocytes - metabolism | Inducible T-Cell Co-Stimulator Protein - immunology | Inducible T-Cell Co-Stimulator Ligand - immunology | Receptors, CXCR5 - metabolism | T-Lymphocytes, Helper-Inducer - metabolism | Receptors, CXCR5 - genetics | Immunization - methods | Mice, Inbred C57BL | Immunophenotyping | Mice, Transgenic | Protein Binding - immunology | CD3 Complex - metabolism | Receptors, CXCR5 - immunology | Mice, Knockout | Animals | B-Lymphocytes - immunology | Germinal Center - metabolism | Ovalbumin - administration & dosage | CD3 Complex - immunology | Cell Line, Tumor | Lymphocyte Count | Antigens - immunology | Luminescent Proteins - genetics | Mice | Inducible T-Cell Co-Stimulator Protein - metabolism | CD40 Antigens - immunology | Luminescent Proteins - metabolism | Antigen-antibody reactions | Antigens | Genetic aspects | Genotype & phenotype | Rodents | Software | Experiments | Chemokines | Immune system | Index Medicus
Journal Article
Journal Article
The Journal of experimental medicine, ISSN 0022-1007, 2013, Volume 210, Issue 6, pp. 1117 - 1124
Journal Article
Immunity, ISSN 1074-7613, 09/2014, Volume 41, Issue 3, pp. 402 - 413
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2013, Volume 110, Issue 9, pp. 3304 - 3309
Mapping of epitopes recognized by functional monoclonal antibodies (mAbs) is essential for understanding the nature of immune responses and designing improved... 
Proteins | Antigens | Pathogens | Carrier proteins | Vaccination | Epitope mapping | Antibodies | Neisseria meningitidis | Libraries | Epitopes | Surface plasmon resonance | Structural mass spectrometry | Structure | Antigen-antibody complex | Meningococcus | SURVIVAL | SITE | BACTERICIDAL ANTIBODY | MULTIDISCIPLINARY SCIENCES | NEISSERIA-MENINGITIDIS | SEROGROUP-B | MONOCLONAL-ANTIBODY | structural mass spectrometry | structure | REGION | FHBP | antigen-antibody complex | surface plasmon resonance | meningococcus | RESPIRATORY SYNCYTIAL VIRUS | BLOOD | Meningococcal Infections - immunology | Surface Plasmon Resonance | Epitope Mapping | Antigens, Bacterial - immunology | Bacterial Proteins - chemistry | Crystallography, X-Ray | Virulence Factors - immunology | Meningococcal Infections - microbiology | Epitopes - immunology | Neisseria meningitidis - immunology | Deuterium Exchange Measurement | Antibody Specificity - immunology | Mass Spectrometry | Bacterial Proteins - immunology | Antibodies, Monoclonal - immunology | Neisseria meningitidis - pathogenicity | Antigens, Bacterial - chemistry | Peptides - chemistry | Peptides - immunology | Models, Molecular | Meningococcal Infections - prevention & control | Virulence Factors - chemistry | Protein Binding - immunology | Cell Surface Display Techniques | Epitopes - chemistry | Meningococcal Vaccines - immunology | Physiological aspects | Virulence (Microbiology) | Research | Binding proteins | Drug therapy | Health aspects | Meningococcal infections | Peptides | Monoclonal antibodies | Bacteria | Vaccines | Mass spectrometry | Crystallography | Index Medicus | Biological Sciences
Journal Article
Immunity, ISSN 1074-7613, 01/2013, Volume 38, Issue 1, pp. 176 - 186
Journal Article
Immunity, ISSN 1074-7613, 11/2012, Volume 37, Issue 5, pp. 827 - 839
Journal Article