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Journal Article
Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 8, pp. 838 - 849
Interferon-gamma (IFN-gamma) primes macrophages for enhanced microbial killing and inflammatory activation by Toll-like receptors (TLRs), but little is known... 
BACTERIAL PATHOGENS | DENDRITIC CELLS | PATHWAY | IMMUNE-RESPONSES | KINASE | IMMUNOLOGY | POLARIZATION | EXPRESSION | TRYPTOPHAN CATABOLISM | MTOR | I INTERFERON | Toll-Like Receptor 2 - genetics | TOR Serine-Threonine Kinases - metabolism | Homeodomain Proteins - metabolism | Humans | Protein Biosynthesis - immunology | Eukaryotic Initiation Factor-4E - metabolism | Multiprotein Complexes - genetics | Gene Expression Profiling | Intracellular Signaling Peptides and Proteins - metabolism | Multiprotein Complexes - metabolism | TOR Serine-Threonine Kinases - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | RNA Interference | Base Sequence | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Macrophage Activation - immunology | Signal Transduction - genetics | Toll-Like Receptor 2 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Macrophages - metabolism | Signal Transduction - drug effects | Toll-Like Receptor 2 - immunology | Protein Biosynthesis - drug effects | MicroRNAs - genetics | Multiprotein Complexes - immunology | RNA, Messenger - immunology | Transcription Factor HES-1 | Macrophage Activation - genetics | Intracellular Signaling Peptides and Proteins - immunology | Homeodomain Proteins - immunology | Mechanistic Target of Rapamycin Complex 1 | Signal Transduction - immunology | Eukaryotic Initiation Factor-4E - immunology | Protein Biosynthesis - genetics | Eukaryotic Initiation Factor-4E - genetics | Macrophages - immunology | RNA, Messenger - genetics | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Homeodomain Proteins - genetics | TOR Serine-Threonine Kinases - immunology | Interferon-gamma - immunology | Basic Helix-Loop-Helix Transcription Factors - immunology | Macrophages - drug effects | Protein-Serine-Threonine Kinases - immunology | Macrophage Activation - drug effects | Interferon-gamma - pharmacology | Microscopy, Fluorescence
Journal Article
Immunity, ISSN 1074-7613, 10/2013, Volume 39, Issue 4, pp. 633 - 645
Combination antiretroviral therapy for HIV infection improves immune function and eliminates the risk of AIDS-related complications but does not restore full... 
MUCOSAL IMMUNE RECONSTITUTION | RECEIVING ANTIRETROVIRAL THERAPY | MONOCYTE ACTIVATION | INTESTINAL EPITHELIAL BARRIER | CD4(+) T-CELLS | CARDIOVASCULAR-DISEASE EVENTS | RANDOMIZED CONTROLLED-TRIAL | IMMUNOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | MICROBIAL TRANSLOCATION | D-DIMER | Intestinal Mucosa - physiopathology | Age Factors | Humans | Protein Biosynthesis - immunology | HIV - immunology | Monocytes - immunology | Liver - physiopathology | Thrombophilia - etiology | Thrombophilia - immunology | HIV Infections - immunology | Liver - immunology | Intestinal Mucosa - immunology | Monocytes - pathology | Anti-Inflammatory Agents - therapeutic use | Anti-HIV Agents - therapeutic use | Thrombophilia - drug therapy | Thrombophilia - physiopathology | Inflammation - immunology | Immunity, Innate | Inflammation - etiology | Models, Immunological | Multiple Organ Failure - etiology | HIV Infections - complications | Multiple Organ Failure - immunology | HIV Infections - drug therapy | HIV Infections - physiopathology | Multiple Organ Failure - physiopathology | Chronic Disease | Inflammation - physiopathology | Highly active antiretroviral therapy | AIDS vaccines | Analysis | Protein biosynthesis | Inflammation | HIV (Viruses) | Health aspects | HIV infection | Antiretroviral drugs | Acquired immune deficiency syndrome--AIDS | Drug therapy | Human immunodeficiency virus--HIV | Mortality
Journal Article
Journal of experimental medicine, ISSN 0022-1007, 2006, Volume 203, Issue 5, pp. 1259 - 1271
Journal Article
Journal of Immunology, ISSN 0022-1767, 10/2014, Volume 193, Issue 7, pp. 3664 - 3675
Trehalose-6,6-dimycolate (TDM), the mycobacterial cord factor, and its synthetic analog Trehalose-6,6-dibehenate (TDB) bind to the C-type lectin receptors... 
SYK KINASE | MYCOBACTERIUM-TUBERCULOSIS | TARGETED DISRUPTION | CANDIDA-ALBICANS | C-TYPE LECTIN | INDUCIBLE FACTOR 1-ALPHA | GENE-EXPRESSION | NLRP3 INFLAMMASOME | IMMUNOLOGY | NF-KAPPA-B | INNATE IMMUNITY | Dendritic Cells - immunology | Lectins, C-Type - immunology | Protein Biosynthesis - immunology | Intracellular Signaling Peptides and Proteins - immunology | Lectins, C-Type - genetics | Enzyme Activation - immunology | Protein-Tyrosine Kinases - immunology | beta-Glucans - chemistry | Phosphorylation - genetics | Protein-Tyrosine Kinases - genetics | Nitric Oxide Synthase Type II - immunology | Early Growth Response Protein 1 - genetics | Myeloid Differentiation Factor 88 - immunology | Mycobacterium tuberculosis - chemistry | Phosphorylation - immunology | Protein Biosynthesis - genetics | Cord Factors - pharmacology | Phosphorylation - drug effects | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Macrophages - immunology | Hypoxia-Inducible Factor 1, alpha Subunit - immunology | Nitric Oxide - immunology | Early Growth Response Protein 1 - immunology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Membrane Proteins - genetics | CCAAT-Enhancer-Binding Protein-beta - genetics | Cord Factors - chemistry | Toll-Like Receptors - immunology | Myeloid Differentiation Factor 88 - genetics | Membrane Proteins - immunology | Up-Regulation - genetics | Macrophages - cytology | beta-Glucans - pharmacology | Enzyme Activation - drug effects | Mice, Knockout | Up-Regulation - drug effects | Animals | Nitric Oxide Synthase Type II - genetics | Up-Regulation - immunology | CCAAT-Enhancer-Binding Protein-beta - immunology | Nitric Oxide - genetics | Toll-Like Receptors - genetics | Protein Biosynthesis - drug effects | Dendritic Cells - cytology | Mice | Granulocyte Colony-Stimulating Factor - immunology | Enzyme Activation - genetics
Journal Article
Nature, ISSN 0028-0836, 11/2010, Volume 468, Issue 7322, pp. 452 - 456
Cellular messenger RNA (mRNA) of higher eukaryotes and many viral RNAs are methylated at the N-7 and 2'-O positions of the 5' guanosine cap by specific nuclear... 
METHYLTRANSFERASE | INITIATION | MULTIDISCIPLINARY SCIENCES | GENES | ALPHA | NILE-VIRUS-INFECTION | INDUCTION | PROTEINS | TRANSLATION | IDENTIFICATION | PROTECTS | Poxviridae - genetics | RNA Caps - immunology | Humans | Methyltransferases - metabolism | Immunity, Innate - genetics | Protein Biosynthesis - immunology | Interferons - immunology | Neoplasm Proteins - metabolism | RNA Caps - metabolism | RNA, Viral - genetics | West Nile virus - genetics | Fibroblasts | Poxviridae - physiology | RNA, Viral - metabolism | Receptor, Interferon alpha-beta - genetics | Interferons - genetics | Neoplasm Proteins - genetics | Coronavirus - physiology | RNA Caps - genetics | West Nile virus - physiology | Poxviridae - enzymology | West Nile virus - immunology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Receptor, Interferon alpha-beta - deficiency | Mice, Inbred C57BL | Cells, Cultured | Survival Rate | Poxviridae - immunology | Interferons - deficiency | Coronavirus - immunology | Proteins - genetics | Carrier Proteins - genetics | Immunity, Innate - immunology | Models, Immunological | Animals | Carrier Proteins - metabolism | Proteins - metabolism | Virus Replication | Coronavirus - genetics | RNA, Viral - immunology | West Nile virus - enzymology | Mice | Models, Genetic | Coronavirus - enzymology | Methylation | 3T3 Cells | West Nile fever | Interferon | Messenger RNA | Methyltransferases | Mortality | Viruses | Infections | Pattern recognition | Experiments | Viral infections | Cytoplasm | Evacuations & rescues
Journal Article