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Journal Article
Neuroscience, ISSN 0306-4522, 2011, Volume 193, pp. 440 - 451
Abstract Paclitaxel chemotherapy is limited by a long-lasting painful neuropathy that lacks an effective therapy. In this study, we tested the hypothesis that... 
Neurology | mast cell tryptase | paclitaxel-induced pain | TRPV1 | TRPA1 | proteinase-activated receptor 2 | TRPV4 | Proteinase-activated receptor 2 | Mast cell tryptase | Paclitaxel-induced pain | NEUROSCIENCES | SENSORY NEURONS | CAPSAICIN RECEPTOR | MECHANICAL HYPERALGESIA | IN-VIVO | KINASE-C-EPSILON | ION-CHANNEL | PERIPHERAL NEUROPATHY | INFLAMMATORY PAIN | PROTEASE-ACTIVATED-RECEPTOR-2 SENSITIZES | IRRITABLE-BOWEL-SYNDROME | Tryptases - metabolism | Central Nervous System - metabolism | Capsaicin - pharmacology | Receptor, PAR-2 - metabolism | Type C Phospholipases - metabolism | Male | Neuralgia - pathology | Dose-Response Relationship, Drug | TRPV Cation Channels - metabolism | Receptor, PAR-2 - antagonists & inhibitors | Drug Interactions | Paclitaxel - toxicity | Time Factors | Protein Kinase C - metabolism | TRPV Cation Channels - antagonists & inhibitors | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Neuralgia - chemically induced | Neuralgia - physiopathology | Disease Models, Animal | Cyclic AMP-Dependent Protein Kinases - metabolism | Enzyme Inhibitors - pharmacology | Capsaicin - analogs & derivatives | Sulfonamides - pharmacology | Cinnamates - pharmacology | Mice, Inbred ICR | Hyperalgesia - physiopathology | Antineoplastic Agents, Phytogenic - toxicity | Gene Expression Regulation - drug effects | Pain Measurement - methods | Pyrroles - pharmacology | Animals | Analysis of Variance | Ankyrins - antagonists & inhibitors | Anilides - pharmacology | Ankyrins - metabolism | Central Nervous System - drug effects | Mice | Physical Stimulation - adverse effects | Carbazoles - pharmacology | Oligopeptides - pharmacology | Protein Kinase C - pharmacology | Enzymes | Care and treatment | Neurosciences | Paclitaxel | Phospholipases | Protein kinases | Cancer
Journal Article
Neuron, ISSN 0896-6273, 2006, Volume 49, Issue 4, pp. 589 - 601
Dopamine neurons in the ventral tegmental area (VTA) represent a critical site of synaptic plasticity induced by addictive drugs. Orexin/hypocretin-containing... 
SYSNEURO | HUMDISEASE | MOLNEURO | PROTEIN-KINASE-C | AMPA RECEPTORS | NMDA RECEPTORS | HYPOTHALAMIC NEUROPEPTIDES | LONG-TERM POTENTIATION | RAT-BRAIN | NEUROSCIENCES | MIDBRAIN DOPAMINERGIC-NEURONS | VENTRAL TEGMENTAL AREA | METHYL-D-ASPARTATE | NUCLEUS-ACCUMBENS | Benzoxazoles - pharmacology | Neuronal Plasticity - drug effects | Male | N-Methylaspartate - pharmacology | Drug Interactions | Neuronal Plasticity - physiology | Cyclic AMP - analogs & derivatives | Time Factors | Neuropeptides - pharmacology | Behavior, Animal - drug effects | Lysine - metabolism | Anesthetics, Local - administration & dosage | Dopamine - metabolism | Animals, Newborn | Lysine - analogs & derivatives | Synapses - drug effects | Neuronal Plasticity - radiation effects | Enzyme Inhibitors - pharmacology | Rats | Behavior, Animal - physiology | Excitatory Amino Acid Agonists - pharmacology | Thionucleotides - pharmacology | Rats, Sprague-Dawley | Immunohistochemistry - methods | Cocaine - administration & dosage | Analysis of Variance | Urea - pharmacology | Intracellular Signaling Peptides and Proteins - pharmacology | Motor Activity - physiology | Tyrosine 3-Monooxygenase - metabolism | Excitatory Postsynaptic Potentials - radiation effects | Motor Activity - drug effects | Ventral Tegmental Area - cytology | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Dose-Response Relationship, Drug | Excitatory Postsynaptic Potentials - physiology | Quinoxalines - pharmacology | Urea - analogs & derivatives | Neurons - physiology | Neurons - drug effects | Electric Stimulation - methods | Orexins | Synapses - physiology | Calcium Channel Blockers - pharmacology | Cyclic AMP - pharmacology | Animals | In Vitro Techniques | Protein Kinase C - pharmacology | Methyl aspartate | Dopamine | Universities and colleges | Neurons | Brain | Neurosciences | Rodents | Addictive behaviors | Cocaine | Behavior | Kinases
Journal Article
Diabetes, ISSN 0012-1797, 11/2000, Volume 49, Issue 11, pp. 1939 - 1945
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, p. e104200
Elevated levels of erythrocyte-derived microparticles are present in the circulation in medical conditions affecting the red blood cells. Erythrocyte-derived... 
FACTOR XA | THROMBIN GENERATION | FACTOR-IXA | TISSUE FACTOR PATHWAY | FACTOR VA | MULTIDISCIPLINARY SCIENCES | VITAMIN-K | TFPI-ALPHA | SICKLE-CELL-DISEASE | FLOW-CYTOMETRY | FACTOR PATHWAY INHIBITOR | Thromboplastin - pharmacology | Factor Va - pharmacology | Annexin A5 - pharmacology | Humans | Cell-Derived Microparticles - chemistry | Ultracentrifugation | Erythrocytes - chemistry | Protein C - pharmacology | Protein S - metabolism | Lipoproteins - antagonists & inhibitors | Factor VIIIa - metabolism | Thrombin - biosynthesis | Cell-Derived Microparticles - drug effects | Lipoproteins - metabolism | Antigens, Surface - metabolism | Protein S - pharmacology | Cell-Derived Microparticles - metabolism | Factor VIIIa - pharmacology | Milk Proteins - metabolism | Factor V - metabolism | Phosphatidylserines - metabolism | Cells, Cultured | Phosphatidylserines - chemistry | Calcimycin - pharmacology | Factor Xa - metabolism | Antibodies - pharmacology | Blood Coagulation - drug effects | Factor Va - metabolism | Blood Coagulation Tests | Protein C - metabolism | Thromboplastin - metabolism | Monoclonal antibodies | Thrombin | Protein C | Ionophores | Protein binding | Flow cytometry | Blood coagulation | Sickle cell anemia | Laboratories | Prothrombinase | Erythrocytes | Tissue factor | Coagulation | Assaying | Blood | Microparticles | Cofactors | Proteins | Red blood cells | Blood platelets | Inhibition | Calcimycin | Sickle cell disease | Phosphatidylserine | Anticoagulants | Enzymes | Incubation | Blood cells | Activated protein C | Medicine | Cytometry | Hospitals | Blood circulation | Protein S | In vivo methods and tests | Annexin V | Medicinal Chemistry | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Läkemedelskemi | Medicinska och farmaceutiska grundvetenskaper
Journal Article