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Journal Article
Journal Article
Journal Article
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 10/2009, Volume 86, Issue 4, pp. 863 - 875
Endotoxin tolerance interferes with TLR4 signalosome assembly, kinase/transcription factor activation, and increases negative TLR pathway regulators. Endotoxin... 
monocytes/macrophages | lipopolysaccharide | signal transduction | suppression/anergy | cell activation | Lipopolysaccharide | Signal transduction | Cell activation | Monocytes/macrophages | Suppression/anergy | STRANDED-RNA | ACTIVATION | DOWN-REGULATION | NECROSIS-FACTOR-ALPHA | BACTERIAL FLAGELLIN | IMMUNOLOGY | CUTTING EDGE | CELL BIOLOGY | RECEPTOR-ASSOCIATED KINASE | TOLL-LIKE RECEPTORS | HEMATOLOGY | NF-KAPPA-B | INNATE IMMUNITY | Protein Kinase C - genetics | Cytoskeletal Proteins - genetics | Humans | Adaptor Proteins, Vesicular Transport - genetics | Suppressor of Cytokine Signaling 1 Protein | Monocytes - metabolism | Monocytes - immunology | Armadillo Domain Proteins - genetics | Adaptor Proteins, Vesicular Transport - metabolism | Interferon Regulatory Factor-3 - genetics | Lipopolysaccharides - immunology | Signal Transduction - immunology | Protein Kinase C - metabolism | Myeloid Differentiation Factor 88 - immunology | Cytoskeletal Proteins - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Cytokines - genetics | Protein-Serine-Threonine Kinases - metabolism | Cytokines - immunology | Interferon Regulatory Factor-3 - immunology | Cell Line | Cytokines - metabolism | Gene Expression Regulation - immunology | Suppressor of Cytokine Signaling Proteins - immunology | Myeloid Differentiation Factor 88 - genetics | Protein-Serine-Threonine Kinases - genetics | Suppressor of Cytokine Signaling Proteins - genetics | Toll-Like Receptor 4 - genetics | p38 Mitogen-Activated Protein Kinases - genetics | Protein Kinase C - immunology | Toll-Like Receptor 4 - immunology | p38 Mitogen-Activated Protein Kinases - immunology | Adaptor Proteins, Vesicular Transport - immunology | Armadillo Domain Proteins - immunology | Toll-Like Receptor 4 - metabolism | Gene Expression Regulation - drug effects | Cytoskeletal Proteins - immunology | Signal Transduction - drug effects | Armadillo Domain Proteins - metabolism | Lipopolysaccharides - pharmacology | Interferon Regulatory Factor-3 - metabolism | Protein-Serine-Threonine Kinases - immunology | Suppressor of Cytokine Signaling Proteins - metabolism | Myeloid Differentiation Factor 88 - metabolism | monocytes | macrophages | suppression | Receptors, Signal Transduction, & Genes | anergy
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2011, Volume 128, Issue 6, pp. 1216 - 1224.e11
Background Disruption of the epithelial barrier might be a risk factor for allergen sensitization and asthma. Viral respiratory tract infections are strongly... 
Allergy and Immunology | Toll-like receptor 3 | epithelial permeability | polyI:C | tight junctions | adherens junctions | protein kinase C | Asthma | SELECTIVE-INHIBITION | APOPTOSIS | ACTIVATION | E-CADHERIN | IMMUNOLOGY | MYOSIN-II | ALLERGY | STRUCTURAL BASIS | C-ALPHA | SECRETION | EXPRESSION | Asthma - metabolism | Epithelial Cells - metabolism | Interferon Inducers - metabolism | Humans | Immunoblotting | Respiratory Mucosa - pathology | Signal Transduction - immunology | RNA Interference | Protein Kinase C - metabolism | Respiratory Mucosa - immunology | Asthma - immunology | Poly I-C - immunology | Interferon Inducers - immunology | Respiratory Tract Infections - pathology | Tight Junctions - metabolism | Cell Line | Respiratory Tract Infections - metabolism | Epithelial Cells - pathology | Protein Kinase C - immunology | Permeability | Tight Junctions - immunology | Poly I-C - metabolism | Epithelial Cells - immunology | Respiratory Tract Infections - immunology | Respiratory Mucosa - metabolism | Asthma - pathology | Microscopy, Fluorescence | Tight Junctions - pathology | Allergens | Antiviral agents | RNA | Genes | Myosin | Melanoma | Universities and colleges | Muscle proteins | Health aspects | Protein kinases | Risk factors | Proteins | Cell culture | Membranes | Acids | Biopsy | Cytotoxicity | Kinases | Actin
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 05/2018, Volume 141, Issue 5, pp. 1774 - 1785.e7
Sialic acid–binding immunoglobulin-like lectin (Siglec)-8 is a cell-surface protein expressed selectively on human eosinophils, mast cells, and basophils,... 
Siglec-8 | targeting | chronic eosinophilic leukemia | mast cell | immunotoxin | endocytosis | eosinophil | systemic mastocytosis | allergic diseases | HYPERTONIC MEDIUM | COATED PIT FORMATION | IMMUNOLOGY | POTASSIUM-DEPLETION | IN-VITRO | RECEPTOR-MEDIATED ENDOCYTOSIS | IMMUNE-SYSTEM | ALLERGY | CD22 SIGLEC-2 | DEPENDENT ENDOCYTOSIS | RIBOSOME-INACTIVATING PROTEINS | Antigens, CD - immunology | Cell Line | Clathrin - immunology | Mast Cells - immunology | Flow Cytometry - methods | Lectins - immunology | Humans | Cell Death - immunology | Protein Kinase C - immunology | Actins - immunology | Eosinophils - immunology | Protein-Tyrosine Kinases - immunology | Membrane Microdomains - immunology | Basophils - immunology | HEK293 Cells | Antigens, Differentiation, B-Lymphocyte - immunology | Cell Line, Tumor | Ligands | Endocytosis - immunology | Allergy | Cell death | Leukemia | Therapeutics | Lectins | Allergic reaction | Protein kinases | Homeopathy | Materia medica and therapeutics | Flow cytometry | Clathrin | Protein kinase C | Saporin | Trafficking | Rafts | Confocal microscopy | Lipid rafts | Cell surface | Endocytosis | Spacecraft components | Actin | Penicillin | Peripheral blood | Protein-tyrosine kinase | Tyrosine | Blood & organ donations | Leukocytes (eosinophilic) | Medical treatment | Cloning | Pharmacology | Chemical compounds | Histamine | Cytometry | Microscopy | Cell lines | Mast cells | Immunoreceptor tyrosine-based inhibition motif | Leukocytes (basophilic) | Mast cell leukemia | Apoptosis | Payloads | Eosinophils
Journal Article