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Cellular Signalling, ISSN 0898-6568, 2006, Volume 18, Issue 3, pp. 276 - 284
Journal Article
Hepatology, ISSN 0270-9139, 04/2014, Volume 59, Issue 4, pp. 1543 - 1554
This study examines the role of protein kinase C (PKC) and AMP‐activated kinase (AMPK) in acetaminophen (APAP) hepatotoxicity. Treatment of primary mouse... 
OXIDATIVE STRESS | ACTIVATION | INHIBITION | RAT HEPATOCYTES | PHORBOL 12-MYRISTATE 13-ACETATE | AUTOPHAGY | GASTROENTEROLOGY & HEPATOLOGY | ISOENZYMES | INDUCED LIVER-INJURY | EXTENDED FAMILY | CELL-DEATH | Acetaminophen - adverse effects | Mitochondria, Liver - metabolism | Maleimides - pharmacology | Hepatocytes - pathology | Male | Hepatocytes - metabolism | Necrosis - pathology | AMP-Activated Protein Kinases - drug effects | Indoles - pharmacology | Chemical and Drug Induced Liver Injury - pathology | Hepatocytes - drug effects | Disease Models, Animal | JNK Mitogen-Activated Protein Kinases - drug effects | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Protein Kinase C - physiology | AMP-Activated Protein Kinases - antagonists & inhibitors | Mice, Inbred C57BL | Protein Kinase C - drug effects | Cells, Cultured | Necrosis - metabolism | Protein Kinase C - antagonists & inhibitors | Chemical and Drug Induced Liver Injury - physiopathology | Mitochondria, Liver - drug effects | AMP-Activated Protein Kinases - physiology | Animals | Chemical and Drug Induced Liver Injury - metabolism | JNK Mitogen-Activated Protein Kinases - physiology | Signal Transduction - physiology | Mice | Protein Kinase Inhibitors - pharmacology | In Vitro Techniques | Cytotoxicity | Mitochondria | Kinases | Autophagy | Liver | Hepatology | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 2123 - 2135
The G protein coupled estrogen receptor (GPER) mediates both the genomic and nongenomic effects of estrogen and has been implicated in breast cancer... 
MIGRATION | MEDICINE, RESEARCH & EXPERIMENTAL | DRUG-THERAPY | ACTIVATION | PATHWAY | GROWTH | GPR30 | PROTEIN-COUPLED RECEPTORS | SIZE-CONTROL | TAZ | 17-BETA-ESTRADIOL | Carcinoma, Ductal, Breast - genetics | Neoplasms, Hormone-Dependent - metabolism | Protein-Serine-Threonine Kinases - analysis | Phosphorylation | Estrogens - pharmacology | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Neoplasms, Hormone-Dependent - physiopathology | Breast Neoplasms - physiopathology | Breast Neoplasms - metabolism | Neoplasms, Hormone-Dependent - genetics | RNA Interference | Phospholipase C beta - physiology | Cell Division | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Female | Transcription, Genetic | Phosphoproteins - physiology | Receptors, G-Protein-Coupled - drug effects | Carcinoma, Ductal, Breast - metabolism | Protein-Serine-Threonine Kinases - metabolism | Receptors, G-Protein-Coupled - physiology | Estrogens - physiology | GTP-Binding Protein alpha Subunits, Gq-G11 - genetics | rho-Associated Kinases - physiology | Transcription Factors - physiology | Protein Kinase C - physiology | Carcinoma, Ductal, Breast - physiopathology | Protein-Serine-Threonine Kinases - physiology | GTP-Binding Protein alpha Subunits, Gq-G11 - antagonists & inhibitors | GTP-Binding Protein alpha Subunits, Gq-G11 - physiology | Tumor Suppressor Proteins - physiology | Adaptor Proteins, Signal Transducing - physiology | Receptors, Estrogen - drug effects | Animals | Breast Neoplasms - genetics | Cell Transformation, Neoplastic | Signal Transduction - physiology | Mice | Mice, Inbred BALB C | Protein Processing, Post-Translational | Cell Movement | Receptors, Estrogen - physiology | Tumor Suppressor Proteins - analysis | Cell receptors | Estrogen | Physiological aspects | Development and progression | Breast cancer | Cellular signal transduction | Research | Studies | Kinases | Rodents | Oncology
Journal Article