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PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, p. e81773
Vascular endothelial growth factor (VEGF) is supposed to contribute to the pathogenesis of allergic airway disease. VEGF expression is regulated by a variety... 
MAMMALIAN TARGET | RAPAMYCIN MTOR | INDUCIBLE FACTOR-I | EPITHELIAL-CELLS | MULTIDISCIPLINARY SCIENCES | E-SELECTIN | ASTHMA | NF-KAPPA-B | ADHESION MOLECULE-1 ICAM-1 | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | Bronchoalveolar Lavage Fluid | RNA, Small Interfering - genetics | Asthma - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Protein Kinase C-delta - deficiency | Phosphatidylinositol 3-Kinases - metabolism | Vascular Endothelial Growth Factor A - metabolism | Hypersensitivity - complications | Phosphoproteins - metabolism | Th2 Cells - drug effects | RNA Interference | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Ovalbumin - adverse effects | Protein Kinase C-delta - antagonists & inhibitors | Female | Lung - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Cell Line | Lung - pathology | Cytokines - metabolism | Asthma - drug therapy | Th2 Cells - metabolism | Gene Expression Regulation - drug effects | Animals | Signal Transduction - drug effects | Asthma - complications | Protein Kinase Inhibitors - therapeutic use | Lung - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Asthma - pathology | Protein Kinase C-delta - genetics | Lung - immunology | Type 2 diabetes | Analysis | Nitric oxide | Inflammation | B cells | Permeability | Vascular endothelial growth factor | Protein kinases | Asthma | TOR protein | Animal models | Protein kinase C | Phosphorylation | Hypoxia-inducible factor 1 | Disease | Pathogenesis | Medical innovations | AKT protein | Smooth muscle | Kinases | Proteins | Angiogenesis | Airway management | Embryology | Hypoxia-inducible factor 1a | Cell growth | Rodents | Tumor necrosis factor-TNF | Respiratory tract diseases | Inhibition | Growth factors | Hypoxia-inducible factors | Cytokines | Leukocytes (eosinophilic) | Medical treatment | Hypersensitivity | Histology | Rapamycin | Allergies | 1-Phosphatidylinositol 3-kinase | Signaling | Protein synthesis | Hypoxia | Regulation | Laboratory animals | Apoptosis
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 6/2014, Volume 49, Issue 3, pp. 1400 - 1421
Journal Article
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 12/2016, Volume 55, Issue 50, pp. 15672 - 15679
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2016, Volume 478, Issue 2, pp. 721 - 726
The molecular bases of disease provide exceptional prospect to translate research findings into new drugs. Nevertheless, to develop new and novel chemical... 
Shikimate kinase | Rottlerin | PKC-δ | Mycobacteria | BIOPHYSICS | PKC-delta | PATHWAY | TUBERCULOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GREEN TEA POLYPHENOL | Phosphotransferases (Alcohol Group Acceptor) - chemistry | Monocytes - cytology | Humans | Monocytes - metabolism | Mycobacterium tuberculosis - drug effects | Benzopyrans - chemistry | Microbial Sensitivity Tests | Protein Kinase Inhibitors - chemistry | Acetophenones - pharmacology | Cloning, Molecular | Escherichia coli - metabolism | Protein Kinase C-delta - antagonists & inhibitors | Benzopyrans - pharmacology | Mycobacterium smegmatis - enzymology | Recombinant Proteins - metabolism | Cell Line | Mycobacterium smegmatis - growth & development | Gene Expression | Protein Structure, Secondary | Recombinant Proteins - chemistry | Phosphotransferases (Alcohol Group Acceptor) - genetics | Recombinant Proteins - genetics | Drug Repositioning | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Monocytes - drug effects | Protein Kinase C-delta - metabolism | Phosphotransferases (Alcohol Group Acceptor) - antagonists & inhibitors | Acetophenones - chemistry | Escherichia coli - genetics | Mycobacterium tuberculosis - enzymology | Mycobacterium smegmatis - drug effects | Molecular Docking Simulation | Protein Kinase Inhibitors - pharmacology | Kinetics | Protein Kinase C-delta - genetics | Mycobacterium tuberculosis - growth & development | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 05/2017, Volume 31, Issue 5, pp. 685 - 696.e6
Constitutive activation of Gαq signaling by mutations in GNAQ or GNA11 occurs in over 80% of uveal melanomas (UMs) and activates MAPK. Protein kinase C (PKC)... 
uveal melanoma | GNAQ | GNA11 | PKC | RasGRP3 | melanoma | DAG | MAPK | RasGEF | CELLS | PROTEIN-KINASE-C | INHIBITION | ONCOLOGY | RAS | PHOSPHORYLATION | COUPLED RECEPTORS | MUTATIONS | MANNER | CANCER | SIGNALING SYSTEMS | CELL BIOLOGY | Phosphorylation | Cell Proliferation | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Melanoma - enzymology | Extracellular Signal-Regulated MAP Kinases - metabolism | Uveal Neoplasms - enzymology | Transfection | Diglycerides - metabolism | RNA Interference | Time Factors | Guanine Nucleotide Exchange Factors - metabolism | Melanoma - genetics | Protein Kinase C-delta - antagonists & inhibitors | Protein Kinase C-epsilon - antagonists & inhibitors | GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism | GTP-Binding Protein alpha Subunits, Gq-G11 - genetics | Uveal Neoplasms - genetics | Guanine Nucleotide Exchange Factors - genetics | Uveal Neoplasms - pathology | Protein Kinase C-epsilon - genetics | GTP-Binding Protein alpha Subunits - genetics | Melanoma - pathology | Tumor Burden | Uveal Neoplasms - drug therapy | Protein Kinase C-delta - metabolism | Animals | MAP Kinase Signaling System - drug effects | Mice, Nude | Melanoma - drug therapy | Protein Kinase C-epsilon - metabolism | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Mutation | Protein Kinase C-delta - genetics | Protein kinases | Melanoma
Journal Article
Journal Article
Archives of Toxicology, ISSN 0340-5761, 4/2016, Volume 90, Issue 4, pp. 937 - 953
Journal Article
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 11/2016, Volume 100, Issue 5, pp. 1027 - 1035
Journal Article