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Journal Article
Nature, ISSN 0028-0836, 2014, Volume 514, Issue 7521, pp. 187 - 192
The murine caspase-11 non-canonical inflammasome responds to various bacterial infections. Caspase-11 activation-induced pyroptosis, in response to cytoplasmic... 
ACTIVATION | GRAM-NEGATIVE BACTERIA | MULTIDISCIPLINARY SCIENCES | CYTOPLASMIC LPS | NLRP3 | LIPID IVA | MECHANISMS | PYROPTOSIS | PROTEINS | TLR4 | LIPOPOLYSACCHARIDE RECOGNITION | Surface Plasmon Resonance | Epithelial Cells - metabolism | Caspases - immunology | Humans | Lipopolysaccharides - metabolism | Substrate Specificity | Caspases, Initiator - genetics | Genetic Complementation Test | Lipopolysaccharides - immunology | Caspases - metabolism | Caspases, Initiator - metabolism | Protein Multimerization - genetics | Cell Death - drug effects | Caspases - chemistry | Epithelial Cells - cytology | Caspases, Initiator - immunology | Lipid A - metabolism | Caspases - genetics | Cells, Cultured | Rhodobacter sphaeroides - chemistry | Mutant Proteins - metabolism | Keratinocytes - cytology | Macrophages - cytology | Enzyme Activation - drug effects | Immunity, Innate | Necrosis - chemically induced | Macrophages - metabolism | Animals | Rhodobacter sphaeroides - immunology | Keratinocytes - metabolism | Caspases, Initiator - chemistry | Mutant Proteins - chemistry | Lipopolysaccharides - pharmacology | Protein Binding | Macrophages - drug effects | Mice | Enzyme Activation - genetics | Inflammation - enzymology | Protein Multimerization - drug effects | Lipids | Septic shock | Immune response | Health aspects | Analysis | Proteins | Salmonella | Bacterial infections | E coli | Bacteria | Cytotoxicity | Mutation | Apoptosis | Index Medicus
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2013, Volume 288, Issue 22, pp. 15813 - 15820
Journal Article
Nature, ISSN 0028-0836, 12/2011, Volume 480, Issue 7377, pp. 387 - 390
Journal Article
Nature, ISSN 0028-0836, 05/2016, Volume 534, Issue 7605, pp. 129 - 132
The epidermal growth factor receptor (EGFR)-directed tyrosine kinase inhibitors (TKIs) gefitinib, erlotinib and afatinib are approved treatments for non-small... 
CELL LUNG-CANCER | EGFR KINASE | GROWTH-FACTOR RECEPTOR | TARGETED THERAPIES | GEFITINIB | ACTIVATION | MECHANISM | MULTIDISCIPLINARY SCIENCES | MUTATIONS | AZD9291 | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Drug Resistance, Multiple - drug effects | Protein Conformation - drug effects | Lung Neoplasms - pathology | Receptor, Epidermal Growth Factor - metabolism | Antineoplastic Agents - pharmacology | Benzeneacetamides - pharmacology | Mutant Proteins - antagonists & inhibitors | Disease Models, Animal | Allosteric Regulation - drug effects | Carcinoma, Non-Small-Cell Lung - pathology | Drug Resistance, Multiple - genetics | Lung Neoplasms - enzymology | Allosteric Site - drug effects | Mutant Proteins - genetics | Cetuximab - pharmacology | Mutant Proteins - metabolism | Receptor, Epidermal Growth Factor - chemistry | Drug Synergism | Drug Resistance, Neoplasm - genetics | Animals | Mutant Proteins - chemistry | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Protein Multimerization - drug effects | Drug Resistance, Neoplasm - drug effects | Studies | Phosphorylation | Nuclear magnetic resonance--NMR | Epidermal growth factor | Mutation | Kinases | Enzyme kinetics | Tumors | Index Medicus
Journal Article
Journal Article
Journal Article